Metabolic syndrome

Factors involved in megakaryocyte development and platelet production

Rap1 signaling pathway PI3K-Akt signaling pathway

Notch signaling pathway Th1 and Th2 cell differentiation Human papillomavirus infection Pre-NOTCH Transcription and Translation NOTCH1 Intracellular Domain Regulates Transcription NOTCH2 intracellular domain regulates transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway RUNX3 regulates NOTCH signaling NOTCH3 Intracellular Domain Regulates Transcription NOTCH4 Intracellular Domain Regulates Transcription +9 more

N-Glycan biosynthesis Various types of N-glycan biosynthesis Metabolic pathways Protein processing in endoplasmic reticulum Intra-Golgi traffic Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 +3 more

N-Glycan biosynthesis Various types of N-glycan biosynthesis Metabolic pathways Protein processing in endoplasmic reticulum Intra-Golgi traffic Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 +3 more

EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway ErbB signaling pathway Ras signaling pathway Rap1 signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway HIF-1 signaling pathway FoxO signaling pathway Sphingolipid signaling pathway Phospholipase D signaling pathway Autophagy - animal Efferocytosis mTOR signaling pathway PI3K-Akt signaling pathway Apoptosis Cellular senescence Vascular smooth muscle contraction VEGF signaling pathway Apelin signaling pathway Gap junction Signaling pathways regulating pluripotency of stem cells Neutrophil extracellular trap formation Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Estrogen signaling pathway Melanogenesis Prolactin signaling pathway Thyroid hormone signaling pathway Oxytocin signaling pathway Relaxin signaling pathway GnRH secretion Cushing syndrome Growth hormone synthesis, secretion and action Alzheimer disease Pathways of neurodegeneration - multiple diseases Salmonella infection Yersinia infection Hepatitis C Hepatitis B Human cytomegalovirus infection Influenza A Human papillomavirus infection Human T-cell leukemia virus 1 infection Kaposi sarcoma-associated herpesvirus infection Human immunodeficiency virus 1 infection Pathways in cancer Proteoglycans in cancer MicroRNAs in cancer Chemical carcinogenesis - receptor activation Chemical carcinogenesis - reactive oxygen species Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer Breast cancer Hepatocellular carcinoma Gastric cancer Central carbon metabolism in cancer Choline metabolism in cancer PD-L1 expression and PD-1 checkpoint pathway in cancer MAPK1 (ERK2) activation Frs2-mediated activation Signal transduction by L1 Uptake and function of anthrax toxins RAF activation MAP2K and MAPK activation Negative feedback regulation of MAPK pathway Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Signaling downstream of RAS mutants +87 more

MAPK signaling pathway Rap1 signaling pathway Cellular senescence Toll-like receptor signaling pathway Fc epsilon RI signaling pathway TNF signaling pathway Thermogenesis Inflammatory mediator regulation of TRP channels GnRH signaling pathway Growth hormone synthesis, secretion and action Alcoholic liver disease Amyotrophic lateral sclerosis Pathways of neurodegeneration - multiple diseases Salmonella infection Yersinia infection Toxoplasmosis Hepatitis B Epstein-Barr virus infection Human immunodeficiency virus 1 infection PD-L1 expression and PD-1 checkpoint pathway in cancer Lipid and atherosclerosis Oxidative Stress Induced Senescence activated TAK1 mediates p38 MAPK activation Uptake and function of anthrax toxins +21 more

MAPK signaling pathway Gap junction Neurotrophin signaling pathway Oxytocin signaling pathway Fluid shear stress and atherosclerosis +2 more

MAPK signaling pathway ErbB signaling pathway Protein processing in endoplasmic reticulum Osteoclast differentiation Tight junction Toll-like receptor signaling pathway T cell receptor signaling pathway Fc epsilon RI signaling pathway TNF signaling pathway Neurotrophin signaling pathway GnRH signaling pathway Relaxin signaling pathway Alcoholic liver disease Alzheimer disease Huntington disease Pathways of neurodegeneration - multiple diseases Salmonella infection Yersinia infection Hepatitis B Kaposi sarcoma-associated herpesvirus infection Epstein-Barr virus infection Human immunodeficiency virus 1 infection Chemical carcinogenesis - reactive oxygen species Lipid and atherosclerosis Fluid shear stress and atherosclerosis Oxidative Stress Induced Senescence FCERI mediated MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 Uptake and function of anthrax toxins +26 more

MAPK signaling pathway Ubiquitin mediated proteolysis Tight junction RIG-I-like receptor signaling pathway Neurotrophin signaling pathway GnRH signaling pathway Growth hormone synthesis, secretion and action Hepatitis B Human T-cell leukemia virus 1 infection MyD88:MAL(TIRAP) cascade initiated on plasma membrane FCERI mediated MAPK activation TRAF6 mediated NF-kB activation TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation MyD88 cascade initiated on plasma membrane +11 more

MAPK signaling pathway

MAPK signaling pathway Alzheimer disease Parkinson disease Pathways of neurodegeneration - multiple diseases Caspase-mediated cleavage of cytoskeletal proteins +2 more

RAF activation MAP2K and MAPK activation Negative regulation of MAPK pathway Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Signaling downstream of RAS mutants +5 more

Anchoring of the basal body to the plasma membrane

Neuroactive ligand-receptor interaction Hormone signaling Peptide ligand-binding receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production +2 more

Wnt signaling pathway

Viral life cycle - HIV-1

Post-translational modification: synthesis of GPI-anchored proteins

Pyruvate metabolism Metabolic pathways Carbon metabolism PPAR signaling pathway Citric acid cycle (TCA cycle) +2 more

PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation

Thyroid hormone signaling pathway PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation +1 more

MAPK signaling pathway cGMP-PKG signaling pathway Apelin signaling pathway Oxytocin signaling pathway Parathyroid hormone synthesis, secretion and action Transcriptional misregulation in cancer Fluid shear stress and atherosclerosis Transcriptional activation of mitochondrial biogenesis Circadian Clock Myogenesis +7 more

Efferocytosis Cell surface interactions at the vascular wall

EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway Calcium signaling pathway PI3K-Akt signaling pathway Axon guidance Focal adhesion Adherens junction Bacterial invasion of epithelial cells Epithelial cell signaling in Helicobacter pylori infection Malaria Pathways in cancer Transcriptional misregulation in cancer Proteoglycans in cancer MicroRNAs in cancer Chemical carcinogenesis - reactive oxygen species Renal cell carcinoma Melanoma Non-small cell lung cancer Hepatocellular carcinoma Gastric cancer Central carbon metabolism in cancer PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer Sema4D mediated inhibition of cell attachment and migration RAF/MAP kinase cascade MET Receptor Activation Negative regulation of MET activity PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling MET activates RAS signaling MET activates PI3K/AKT signaling MET activates PTPN11 MET activates PTK2 signaling InlB-mediated entry of Listeria monocytogenes into host cell MET interacts with TNS proteins MET activates RAP1 and RAC1 MET receptor recycling MET activates STAT3 MECP2 regulates neuronal receptors and channels +37 more

Molecules associated with elastic fibres

Synthesis of PC

Polycomb repressive complex Transcriptional Regulation by E2F6

Insulin resistance Non-alcoholic fatty liver disease PKA-mediated phosphorylation of key metabolic factors ChREBP activates metabolic gene expression +1 more

Parathyroid hormone synthesis, secretion and action Activation of Matrix Metalloproteinases

MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway Phospholipase D signaling pathway Mitophagy - animal Autophagy - animal Cellular senescence Apelin signaling pathway C-type lectin receptor signaling pathway Regulation of actin cytoskeleton Proteoglycans in cancer +8 more

rRNA modification in the mitochondrion

Ribosome Mitochondrial translation elongation Mitochondrial translation termination

Ribosome Mitochondrial translation elongation Mitochondrial translation termination