Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
LUNG ADENOCARCINOMA	EFO_0000571	LDLRAD4	Unknown	34290314	GWAS catalog	—
		LEPROT	Unknown	40341939	GWAS catalog	—
		LHX3	Unknown	29924316	GWAS catalog	—
		LINC02210-CRHR1	Unknown	32887889	GWAS catalog	Class B/2 (Secretin family receptors) G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
		LMTK2	Unknown	32887889	GWAS catalog	—
		LPAR1	Unknown	32889700	GWAS catalog	Rap1 signaling pathway Phospholipase D signaling pathway Neuroactive ligand-receptor interaction +8 more
		LPCAT1	Unknown	28604730	GWAS catalog	Glycerophospholipid metabolism Ether lipid metabolism Metabolic pathways +5 more
		LRFN1	Unknown	28604730	GWAS catalog	Synaptic adhesion-like molecules
		LRRC2	Unknown	40341939	GWAS catalog	—
		LRRC8D	Unknown	28604730	GWAS catalog	Miscellaneous transport and binding events
		LRRIQ4	Unknown	34290314	GWAS catalog	—
		LSAMP	Unknown	39366959	GWAS catalog	Post-translational modification: synthesis of GPI-anchored proteins
		LUZP2	Unknown	34594039	GWAS catalog	—
		LY6K	Unknown	37340002	GWAS catalog	Post-translational modification: synthesis of GPI-anchored proteins
		MAGI3	Unknown	31577861	GWAS catalog	Rap1 signaling pathway
		MALRD1	Unknown	29924316	GWAS catalog	—
		MAP3K1	Unknown	27197191 32887889 37340002	GWAS catalog	MAPK signaling pathway Ubiquitin mediated proteolysis Tight junction +11 more
		MAP3K20	Unknown	28604730	GWAS catalog	MAPK signaling pathway
		MAP7	Unknown	34062886	GWAS catalog	—
		MATN1	Unknown	40341939	GWAS catalog	ECM proteoglycans
		MCL1	Unknown	34290314	GWAS catalog	PI3K-Akt signaling pathway Apoptosis JAK-STAT signaling pathway +2 more
		MDGA2	Unknown	28604730	GWAS catalog	Post-translational modification: synthesis of GPI-anchored proteins
		MECOM	Unknown	27197191	GWAS catalog	Lysine degradation Metabolic pathways MAPK signaling pathway +4 more
		MEGF9	Unknown	28604730	GWAS catalog	—
		METTL4	Unknown	28604730	GWAS catalog	—
		MICAL2	Unknown	28604730	GWAS catalog	—
		MIER3	Unknown	32887889	GWAS catalog	—
		MIGA1	Unknown	28604730	GWAS catalog	Synthesis of PA
		MINDY4	Unknown	40341939	GWAS catalog	—
		MIPEP	Unknown	21725308	GWAS catalog	—
		MLC1	Unknown	34290314	GWAS catalog	—
		MLLT10	Unknown	32887889	GWAS catalog	—
		MLLT3	Unknown	40341939	GWAS catalog	Viral life cycle - HIV-1 Transcriptional misregulation in cancer Formation of RNA Pol II elongation complex +2 more
		MMP9	Unknown	34290314	GWAS catalog	Endocrine resistance IL-17 signaling pathway TNF signaling pathway +22 more
		MOG	Unknown	28604730 39366959	GWAS catalog	—
		MORF4L1	Unknown	28604730 31577861	GWAS catalog	ATP-dependent chromatin remodeling
		MPZL2	Unknown	28604730 31577861 39366959	GWAS catalog	—
		MPZL3	Unknown	31326317 32889700 35915169 39366959	GWAS catalog	—
		MRPS30	Unknown	34594039	GWAS catalog	Mitochondrial translation elongation Mitochondrial translation termination
		MRTFA	Unknown	32887889 37340002	GWAS catalog	SUMOylation of transcription cofactors RHO GTPases Activate Formins
		MSH5	Unknown	28604730	GWAS catalog	—
		MSLN	Unknown	40341939	GWAS catalog	Post-translational modification: synthesis of GPI-anchored proteins Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
		MSMB	Unknown	32887889	GWAS catalog	—
		MTA3	Unknown	40341939	GWAS catalog	ATP-dependent chromatin remodeling HDACs deacetylate histones RNA Polymerase I Transcription Initiation +1 more
		MTAP	Unknown	27197191 28604730 29924316 31326317 32889700 35915169 39366959	GWAS catalog	Cysteine and methionine metabolism Metabolic pathways Methionine salvage pathway +1 more
		MTMR3	Unknown	21725308	GWAS catalog	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system +3 more
		MTUS1	Unknown	26732429	GWAS catalog	—
		MTX1	Unknown	27197191	GWAS catalog	Mitophagy - animal
		MUC21	Unknown	28604730	GWAS catalog	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUC22	Unknown	28604730	GWAS catalog	—
LUNG CANCER	MONDO_0008903	LDLRAD4	Unknown	34290314	GWAS catalog	—
		LEPROT	Unknown	40341939	GWAS catalog	—
		LRRC8D	Unknown	28604730	GWAS catalog	Miscellaneous transport and binding events
		LRRIQ4	Unknown	34290314	GWAS catalog	—
		LSAMP	Unknown	39366959	GWAS catalog	Post-translational modification: synthesis of GPI-anchored proteins
		LUZP2	Unknown	34594039	GWAS catalog	—
		LY6K	Unknown	37340002	GWAS catalog	Post-translational modification: synthesis of GPI-anchored proteins
		MAGI3	Unknown	31577861	GWAS catalog	Rap1 signaling pathway
		MAP3K1	Unknown	36819030 37340002	GWAS catalog	MAPK signaling pathway Ubiquitin mediated proteolysis Tight junction +11 more
		MAP3K20	Unknown	28604730	GWAS catalog	MAPK signaling pathway
		MAP7	Unknown	34062886	GWAS catalog	—
		MCL1	Unknown	34290314	GWAS catalog	PI3K-Akt signaling pathway Apoptosis JAK-STAT signaling pathway +2 more
		MECOM	Unknown	27197191	GWAS catalog	Lysine degradation Metabolic pathways MAPK signaling pathway +4 more
		MEGF9	Unknown	28604730	GWAS catalog	—
		METTL4	Unknown	28604730	GWAS catalog	—
		MIGA1	Unknown	28604730	GWAS catalog	Synthesis of PA
		MIPEP	Unknown	21725308	GWAS catalog	—
		MLC1	Unknown	34290314	GWAS catalog	—
		MMP9	Unknown	34290314	GWAS catalog	Endocrine resistance IL-17 signaling pathway TNF signaling pathway +22 more
		MOG	Unknown	28604730 39366959	GWAS catalog	—
		MORF4L1	Unknown	28604730 31577861	GWAS catalog	ATP-dependent chromatin remodeling
		MPZL2	Unknown	28604730 31577861 39366959	GWAS catalog	—
		MRPS30	Unknown	34594039	GWAS catalog	Mitochondrial translation elongation Mitochondrial translation termination
		MRTFA	Unknown	37340002	GWAS catalog	SUMOylation of transcription cofactors RHO GTPases Activate Formins
		MSH5	Unknown	28604730 36819030	GWAS catalog	—
		MSLN	Unknown	40341939	GWAS catalog	Post-translational modification: synthesis of GPI-anchored proteins Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
		MTA3	Unknown	40341939	GWAS catalog	ATP-dependent chromatin remodeling HDACs deacetylate histones RNA Polymerase I Transcription Initiation +1 more
		MTAP	Unknown	27197191 28604730 35915169 39366959	GWAS catalog	Cysteine and methionine metabolism Metabolic pathways Methionine salvage pathway +1 more
		MTMR3	Unknown	21725308	GWAS catalog	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system +3 more
		MTUS1	Unknown	26732429	GWAS catalog	—
		MTX1	Unknown	27197191	GWAS catalog	Mitophagy - animal
		MUC21	Unknown	28604730	GWAS catalog	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUC22	Unknown	28604730	GWAS catalog	—
LUNG CARCINOMA	EFO_0001071	LDLRAD4	Unknown	34290314	GWAS catalog	—
		LEPROT	Unknown	40341939	GWAS catalog	—
		LINC02210-CRHR1	Unknown	32887889	GWAS catalog	Class B/2 (Secretin family receptors) G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
		LMTK2	Unknown	32887889	GWAS catalog	—
		LPCAT1	Unknown	28604730	GWAS catalog	Glycerophospholipid metabolism Ether lipid metabolism Metabolic pathways +5 more
		LRRC8D	Unknown	28604730	GWAS catalog	Miscellaneous transport and binding events
		LRRIQ4	Unknown	34290314	GWAS catalog	—
		LSAMP	Unknown	39366959	GWAS catalog	Post-translational modification: synthesis of GPI-anchored proteins
		LUZP2	Unknown	34594039	GWAS catalog	—
		LY6K	Unknown	37340002	GWAS catalog	Post-translational modification: synthesis of GPI-anchored proteins
		MAGI3	Unknown	31577861	GWAS catalog	Rap1 signaling pathway
		MALRD1	Unknown	29924316	GWAS catalog	—
		MAP3K1	Unknown	27197191 32887889 37340002	GWAS catalog	MAPK signaling pathway Ubiquitin mediated proteolysis Tight junction +11 more
		MAP3K20	Unknown	28604730	GWAS catalog	MAPK signaling pathway
		MAP7	Unknown	34062886	GWAS catalog	—
		MCL1	Unknown	34290314	GWAS catalog	PI3K-Akt signaling pathway Apoptosis JAK-STAT signaling pathway +2 more
		MECOM	Unknown	27197191	GWAS catalog	Lysine degradation Metabolic pathways MAPK signaling pathway +4 more
		MEGF9	Unknown	28604730	GWAS catalog	—
		METTL4	Unknown	28604730	GWAS catalog	—
		MIER3	Unknown	32887889	GWAS catalog	—
		MIGA1	Unknown	28604730	GWAS catalog	Synthesis of PA
		MIPEP	Unknown	21725308	GWAS catalog	—
		MLC1	Unknown	34290314	GWAS catalog	—
		MLLT10	Unknown	32887889	GWAS catalog	—
		MMP9	Unknown	34290314	GWAS catalog	Endocrine resistance IL-17 signaling pathway TNF signaling pathway +22 more
		MOG	Unknown	28604730 39366959	GWAS catalog	—
		MORF4L1	Unknown	28604730 31577861	GWAS catalog	ATP-dependent chromatin remodeling
		MPZL2	Unknown	28604730 31577861 39366959	GWAS catalog	—
		MPZL3	Unknown	37846649	GWAS catalog	—
		MRPS30	Unknown	34594039	GWAS catalog	Mitochondrial translation elongation Mitochondrial translation termination
		MRTFA	Unknown	32887889 37340002	GWAS catalog	SUMOylation of transcription cofactors RHO GTPases Activate Formins
		MSH5	Unknown	28604730	GWAS catalog	—
		MSLN	Unknown	40341939	GWAS catalog	Post-translational modification: synthesis of GPI-anchored proteins Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
		MSMB	Unknown	32887889	GWAS catalog	—
		MTA3	Unknown	40341939	GWAS catalog	ATP-dependent chromatin remodeling HDACs deacetylate histones RNA Polymerase I Transcription Initiation +1 more
		MTAP	Unknown	27197191 28604730 35915169 39366959	GWAS catalog	Cysteine and methionine metabolism Metabolic pathways Methionine salvage pathway +1 more
		MTMR3	Unknown	21725308	GWAS catalog	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system +3 more
		MTUS1	Unknown	26732429	GWAS catalog	—
		MTX1	Unknown	27197191	GWAS catalog	Mitophagy - animal
		MUC21	Unknown	28604730	GWAS catalog	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUC22	Unknown	28604730	GWAS catalog	—

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Lung cancer

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