Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
LUNG ADENOCARCINOMA	EFO_0000571	ABT1	Unknown	28604730	GWAS catalog	—
		ACKR2	Unknown	35915169	GWAS catalog	Chemokine receptors bind chemokines
		ACTA2	Unknown	19654303	GWAS catalog	Vascular smooth muscle contraction Apelin signaling pathway Motor proteins +3 more
		ACTR2	Unknown	28604730 31326317 32889700 35915169	GWAS catalog	Endocytosis Tight junction Fc gamma R-mediated phagocytosis +12 more
		ACTRT3	Unknown	28604730 39366959	GWAS catalog	—
		ACVR1B	Unknown	26732429 40783572	GWAS catalog	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +1 more
		ADAMTS7	Unknown	28604730	GWAS catalog	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
		ADAMTS9	Unknown	40341939	GWAS catalog	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
		ADAR	Unknown	28604730	GWAS catalog	RIG-I-like receptor signaling pathway Cytosolic DNA-sensing pathway Measles +5 more
		ADH1B	Unknown	28604730	GWAS catalog	Glycolysis / Gluconeogenesis Fatty acid degradation Tyrosine metabolism +7 more
		ADH1C	Unknown	28604730	GWAS catalog	Glycolysis / Gluconeogenesis Fatty acid degradation Tyrosine metabolism +8 more
		AGER	Unknown	32887889	GWAS catalog	Efferocytosis Neutrophil extracellular trap formation AGE-RAGE signaling pathway in diabetic complications +7 more
		AHR	Unknown	32887889	GWAS catalog	Th17 cell differentiation Cushing syndrome Chemical carcinogenesis - receptor activation +6 more
		AIF1	Unknown	32887889	GWAS catalog	—
		AJAP1	Unknown	40341939	GWAS catalog	—
		AK5	Unknown	28604730 39366959	GWAS catalog	Purine metabolism Thiamine metabolism Metabolic pathways +3 more
		AKR1B10	Unknown	29924316	GWAS catalog	Pentose and glucuronate interconversions Fructose and mannose metabolism Galactose metabolism +4 more
		ANKRD11	Unknown	34290314	GWAS catalog	—
		ANKRD24	Unknown	32887889	GWAS catalog	—
		ANKRD44	Unknown	40341939	GWAS catalog	—
		ANP32A	Unknown	40341939	GWAS catalog	HuR (ELAVL1) binds and stabilizes mRNA
		ANXA9	Unknown	32887889	GWAS catalog	—
		APOM	Unknown	18978787 19654303 19836008 28604730	GWAS catalog	Retinoid metabolism and transport
		AQP3	Unknown	28604730 31326317 32889700 39366959	GWAS catalog	Vasopressin-regulated water reabsorption Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins
		AQP7	Unknown	28604730 31326317 32889700 39366959	GWAS catalog	PPAR signaling pathway Regulation of lipolysis in adipocytes Transport of glycerol from adipocytes to the liver by Aquaporins +1 more
		ARAP3	Unknown	28604730	GWAS catalog	Rap1 signaling pathway cAMP signaling pathway Endocytosis +1 more
		ARHGEF10L	Unknown	33893285	GWAS catalog	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
		ASCL4	Unknown	40341939	GWAS catalog	—
		ASIC2	Unknown	40341939	GWAS catalog	Taste transduction Inflammatory mediator regulation of TRP channels Stimuli-sensing channels
		ASIP	Unknown	27197191 34290314	GWAS catalog	Melanogenesis
		ATAD5	Unknown	32887889	GWAS catalog	—
		ATE1	Unknown	32887889	GWAS catalog	—
		ATM	Unknown	35915169	GWAS catalog	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		ATP8B1	Unknown	34062886 36929942	GWAS catalog	Ion transport by P-type ATPases
		ATP8B4	Unknown	28604730	GWAS catalog	Neutrophil degranulation Ion transport by P-type ATPases
		ATXN2	Unknown	27197191 34290314	GWAS catalog	Amyotrophic lateral sclerosis Spinocerebellar ataxia Pathways of neurodegeneration - multiple diseases
		AZGP1	Unknown	37340002	GWAS catalog	Miscellaneous transport and binding events
		B3GAT1	Unknown	40341939	GWAS catalog	Mannose type O-glycan biosynthesis Metabolic pathways A tetrasaccharide linker sequence is required for GAG synthesis
		BABAM1	Unknown	27197191	GWAS catalog	Homologous recombination Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks +3 more
		BACH1	Unknown	34062886	GWAS catalog	—
		BAD	Unknown	34290314	GWAS catalog	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +44 more
		BAG6	Unknown	18978787 19654303 19836008	GWAS catalog	Protein export
		BAZ1A	Unknown	31326317 32889700	GWAS catalog	ATP-dependent chromatin remodeling
		BCL2L11	Unknown	34290314	GWAS catalog	EGFR tyrosine kinase inhibitor resistance FoxO signaling pathway PI3K-Akt signaling pathway +13 more
		BIK	Unknown	32887889	GWAS catalog	Endocrine resistance
		BNC2	Unknown	33893285	GWAS catalog	—
		BPIFA3	Unknown	34290314	GWAS catalog	—
		BPTF	Unknown	22797724 23143601 27501781 31326317	GWAS catalog	ATP-dependent chromatin remodeling
		BRCA2	Unknown	24880342 27197191 28604730 34290314 35915169 39366959	GWAS catalog	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BTN2A1	Unknown	31577861	GWAS catalog	Butyrophilin (BTN) family interactions
LUNG CANCER	MONDO_0008903	ABT1	Unknown	28604730	GWAS catalog	—
		ACKR2	Unknown	35915169	GWAS catalog	Chemokine receptors bind chemokines
		ACTA2	Unknown	19654303	GWAS catalog	Vascular smooth muscle contraction Apelin signaling pathway Motor proteins +3 more
		ACTR2	Unknown	28604730	GWAS catalog	Endocytosis Tight junction Fc gamma R-mediated phagocytosis +12 more
		ACVR1B	Unknown	26732429 40783572	GWAS catalog	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +1 more
		ADAMTS7	Unknown	28604730	GWAS catalog	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
		ADAMTS9	Unknown	40341939	GWAS catalog	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
		ADAR	Unknown	28604730	GWAS catalog	RIG-I-like receptor signaling pathway Cytosolic DNA-sensing pathway Measles +5 more
		ADH1B	Unknown	28604730	GWAS catalog	Glycolysis / Gluconeogenesis Fatty acid degradation Tyrosine metabolism +7 more
		ADH1C	Unknown	28604730	GWAS catalog	Glycolysis / Gluconeogenesis Fatty acid degradation Tyrosine metabolism +8 more
		AK5	Unknown	28604730 39366959	GWAS catalog	Purine metabolism Thiamine metabolism Metabolic pathways +3 more
		ANKRD11	Unknown	34290314	GWAS catalog	—
		ANKRD44	Unknown	40341939	GWAS catalog	—
		APOM	Unknown	18978787 19654303 28604730	GWAS catalog	Retinoid metabolism and transport
		ARAP3	Unknown	28604730	GWAS catalog	Rap1 signaling pathway cAMP signaling pathway Endocytosis +1 more
		ARHGEF10L	Unknown	33893285	GWAS catalog	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
		ASCL4	Unknown	40341939	GWAS catalog	—
		ASIP	Unknown	27197191 34290314	GWAS catalog	Melanogenesis
		ATP8B1	Unknown	34062886	GWAS catalog	Ion transport by P-type ATPases
		ATP8B4	Unknown	28604730	GWAS catalog	Neutrophil degranulation Ion transport by P-type ATPases
		ATXN2	Unknown	27197191 34290314	GWAS catalog	Amyotrophic lateral sclerosis Spinocerebellar ataxia Pathways of neurodegeneration - multiple diseases
		AZGP1	Unknown	37340002	GWAS catalog	Miscellaneous transport and binding events
		BABAM1	Unknown	27197191	GWAS catalog	Homologous recombination Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks +3 more
		BACH1	Unknown	34062886	GWAS catalog	—
		BAD	Unknown	34290314	GWAS catalog	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +44 more
		BAG6	Unknown	18978787 19654303	GWAS catalog	Protein export
		BCL2L11	Unknown	34290314	GWAS catalog	EGFR tyrosine kinase inhibitor resistance FoxO signaling pathway PI3K-Akt signaling pathway +13 more
		BNC2	Unknown	33893285	GWAS catalog	—
		BPIFA3	Unknown	34290314	GWAS catalog	—
		BPTF	Unknown	23143601	GWAS catalog	ATP-dependent chromatin remodeling
		BRCA2	Unknown	24880342 27197191 28604730 34290314 35915169 39024449 39366959	GWAS catalog	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BTN2A1	Unknown	31577861	GWAS catalog	Butyrophilin (BTN) family interactions
LUNG CARCINOMA	EFO_0001071	ABT1	Unknown	28604730	GWAS catalog	—
		ACKR2	Unknown	35915169	GWAS catalog	Chemokine receptors bind chemokines
		ACTA2	Unknown	19654303	GWAS catalog	Vascular smooth muscle contraction Apelin signaling pathway Motor proteins +3 more
		ACTR2	Unknown	28604730	GWAS catalog	Endocytosis Tight junction Fc gamma R-mediated phagocytosis +12 more
		ACVR1B	Unknown	26732429 40783572	GWAS catalog	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +1 more
		ADAMTS7	Unknown	28604730	GWAS catalog	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
		ADAMTS9	Unknown	40341939	GWAS catalog	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
		ADAR	Unknown	28604730	GWAS catalog	RIG-I-like receptor signaling pathway Cytosolic DNA-sensing pathway Measles +5 more
		ADH1B	Unknown	28604730	GWAS catalog	Glycolysis / Gluconeogenesis Fatty acid degradation Tyrosine metabolism +7 more
		ADH1C	Unknown	28604730	GWAS catalog	Glycolysis / Gluconeogenesis Fatty acid degradation Tyrosine metabolism +8 more
		AGER	Unknown	32887889	GWAS catalog	Efferocytosis Neutrophil extracellular trap formation AGE-RAGE signaling pathway in diabetic complications +7 more
		AHR	Unknown	28604730 32887889	GWAS catalog	Th17 cell differentiation Cushing syndrome Chemical carcinogenesis - receptor activation +6 more
		AIF1	Unknown	32887889	GWAS catalog	—
		AK5	Unknown	28604730 39366959	GWAS catalog	Purine metabolism Thiamine metabolism Metabolic pathways +3 more
		ANKRD11	Unknown	34290314	GWAS catalog	—
		ANKRD24	Unknown	32887889	GWAS catalog	—
		ANKRD44	Unknown	40341939	GWAS catalog	—
		ANXA9	Unknown	32887889	GWAS catalog	—
		APOM	Unknown	18978787 19654303 28604730	GWAS catalog	Retinoid metabolism and transport
		ARAP3	Unknown	28604730	GWAS catalog	Rap1 signaling pathway cAMP signaling pathway Endocytosis +1 more
		ARHGEF10L	Unknown	33893285	GWAS catalog	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
		ASCL4	Unknown	40341939	GWAS catalog	—
		ASIP	Unknown	27197191 34290314	GWAS catalog	Melanogenesis
		ATAD5	Unknown	28604730 32887889	GWAS catalog	—
		ATE1	Unknown	32887889	GWAS catalog	—
		ATP8B1	Unknown	34062886 36929942	GWAS catalog	Ion transport by P-type ATPases
		ATP8B4	Unknown	28604730	GWAS catalog	Neutrophil degranulation Ion transport by P-type ATPases
		ATXN2	Unknown	27197191 34290314	GWAS catalog	Amyotrophic lateral sclerosis Spinocerebellar ataxia Pathways of neurodegeneration - multiple diseases
		AZGP1	Unknown	37340002	GWAS catalog	Miscellaneous transport and binding events
		BABAM1	Unknown	27197191	GWAS catalog	Homologous recombination Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks +3 more
		BACH1	Unknown	34062886 40829600	GWAS catalog	—
		BAD	Unknown	34290314	GWAS catalog	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +44 more
		BAG6	Unknown	18978787 19654303	GWAS catalog	Protein export
		BCL2L11	Unknown	34290314	GWAS catalog	EGFR tyrosine kinase inhibitor resistance FoxO signaling pathway PI3K-Akt signaling pathway +13 more
		BIK	Unknown	32887889	GWAS catalog	Endocrine resistance
		BNC2	Unknown	33893285	GWAS catalog	—
		BPIFA3	Unknown	34290314	GWAS catalog	—
		BPTF	Unknown	23143601 37846649	GWAS catalog	ATP-dependent chromatin remodeling
		BRCA2	Unknown	24880342 27197191 28604730 34290314 35915169 39366959	GWAS catalog	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BTN2A1	Unknown	28604730 31577861	GWAS catalog	Butyrophilin (BTN) family interactions

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Lung cancer

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