Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
LUNG ADENOCARCINOMA	EFO_0000571	CLK1	Unknown	34290314	GWAS catalog	Legionellosis
		CLPTM1L	Unknown	18978787 18978790 19654303 19836008 28604730 31009812 31326317 32887889 34290314 37340002 39366959	GWAS catalog	—
		CLSTN2	Unknown	28604730	GWAS catalog	—
		CLYBL	Unknown	34290314	GWAS catalog	—
		CMSS1	Unknown	32887889	GWAS catalog	—
		CNR1	Unknown	40341939	GWAS catalog	Rap1 signaling pathway Neuroactive ligand-receptor interaction Thermogenesis +3 more
		CNTLN	Unknown	28604730	GWAS catalog	—
		CNTNAP5	Unknown	40341939	GWAS catalog	—
		COL11A1	Unknown	40341939	GWAS catalog	Cytoskeleton in muscle cells Protein digestion and absorption Collagen degradation +5 more
		COL11A2	Unknown	28604730	GWAS catalog	Cytoskeleton in muscle cells Protein digestion and absorption Collagen degradation +5 more
		COL2A1	Unknown	27393504	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +14 more
		COL6A3	Unknown	28604730	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +11 more
		COL6A5	Unknown	28604730	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +11 more
		COL6A6	Unknown	28604730	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +11 more
		COPS2	Unknown	28604730 31326317 32889700 35915169 39366959	GWAS catalog	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis +1 more
		COPS8	Unknown	28604730	GWAS catalog	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis +1 more
		COX6C	Unknown	40829600	GWAS catalog	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction +12 more
		CPNE4	Unknown	40341939	GWAS catalog	—
		CRACD	Unknown	40341939	GWAS catalog	—
		CROT	Unknown	28604730	GWAS catalog	Peroxisome Beta-oxidation of pristanoyl-CoA Peroxisomal protein import
		CRP	Unknown	18385676	GWAS catalog	Classical antibody-mediated complement activation
		CSK	Unknown	28604730	GWAS catalog	Epithelial cell signaling in Helicobacter pylori infection GAB1 signalosome Phosphorylation of CD3 and TCR zeta chains +8 more
		CSMD1	Unknown	34062886	GWAS catalog	—
		CSMD3	Unknown	40341939	GWAS catalog	—
		CYBRD1	Unknown	32887889	GWAS catalog	Mineral absorption Iron uptake and transport
		CYP1A1	Unknown	32889700	GWAS catalog	Steroid hormone biosynthesis Tryptophan metabolism Retinol metabolism +12 more
		CYP1A2	Unknown	28604730 32889700	GWAS catalog	Steroid hormone biosynthesis Caffeine metabolism Tryptophan metabolism +15 more
		CYP2A6	Unknown	28604730 32889700 34594039 35915169 37167549 37340002 38970920 39366959 40341939 40783572	GWAS catalog	Caffeine metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 +7 more
		CYP8B1	Unknown	35915169	GWAS catalog	Primary bile acid biosynthesis Metabolic pathways PPAR signaling pathway +7 more
		DAZL	Unknown	28604730	GWAS catalog	—
		DCAF4	Unknown	34290314	GWAS catalog	Neddylation
		DCBLD1	Unknown	23143601 28604730 31326317 34594039 35915169 37340002 39366959 40783572	GWAS catalog	—
		DCTN4	Unknown	28604730	GWAS catalog	Motor proteins Vasopressin-regulated water reabsorption Amyotrophic lateral sclerosis +7 more
		DDR1	Unknown	28604730	GWAS catalog	Non-integrin membrane-ECM interactions
		DLC1	Unknown	32887889	GWAS catalog	Rho GTPase cycle
		DLG2	Unknown	32699080 40341939	GWAS catalog	Hippo signaling pathway Tight junction Human papillomavirus infection +3 more
		DLGAP2	Unknown	28604730	GWAS catalog	—
		DLGAP4	Unknown	34290314	GWAS catalog	Neurexins and neuroligins
		DNAAF10	Unknown	32887889	GWAS catalog	—
		DNAJB4	Unknown	28604730 35915169	GWAS catalog	—
		DNAJC1	Unknown	32887889	GWAS catalog	Protein processing in endoplasmic reticulum
		DOCK1	Unknown	40341939	GWAS catalog	Efferocytosis Focal adhesion Fc gamma R-mediated phagocytosis +10 more
		DOCK8	Unknown	26732429	GWAS catalog	Factors involved in megakaryocyte development and platelet production
		DPEP1	Unknown	34290314	GWAS catalog	Synthesis of Leukotrienes (LT) and Eoxins (EX) Aflatoxin activation and detoxification LTC4-CYSLTR mediated IL4 production
		DPP6	Unknown	34290314	GWAS catalog	—
		DSP	Unknown	37340002	GWAS catalog	Cytoskeleton in muscle cells Arrhythmogenic right ventricular cardiomyopathy Apoptotic cleavage of cell adhesion proteins +3 more
		DTNB	Unknown	37236969	GWAS catalog	—
		DTWD1	Unknown	28604730	GWAS catalog	—
		DVL1	Unknown	27197191	GWAS catalog	mTOR signaling pathway Wnt signaling pathway Notch signaling pathway +18 more
		EBF1	Unknown	32887889	GWAS catalog	—
LUNG CANCER	MONDO_0008903 MONDO:0008903	CLK1	Unknown	34290314	GWAS catalog	Legionellosis
		CLPTM1L	Unknown	18978787 18978790 19654303 28604730 32887889 34290314 36819030 37340002 39366959 40155373	GWAS catalog	—
		CLSTN2	Unknown	28604730	GWAS catalog	—
		CLYBL	Unknown	34290314	GWAS catalog	—
		CNR1	Unknown	40341939	GWAS catalog	Rap1 signaling pathway Neuroactive ligand-receptor interaction Thermogenesis +3 more
		COL11A2	Unknown	28604730	GWAS catalog	Cytoskeleton in muscle cells Protein digestion and absorption Collagen degradation +5 more
		COL2A1	Unknown	27393504	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +14 more
		COL6A3	Unknown	28604730	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +11 more
		COL6A5	Unknown	28604730	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +11 more
		COL6A6	Unknown	28604730	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +11 more
		COPS2	Unknown	28604730 35915169 39366959	GWAS catalog	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis +1 more
		COPS8	Unknown	28604730	GWAS catalog	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis +1 more
		COX6C	Unknown	40829600	GWAS catalog	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction +12 more
		CRACD	Unknown	40341939	GWAS catalog	—
		CROT	Unknown	28604730	GWAS catalog	Peroxisome Beta-oxidation of pristanoyl-CoA Peroxisomal protein import
		CRP	Unknown	18385676	GWAS catalog	Classical antibody-mediated complement activation
		CSK	Unknown	28604730	GWAS catalog	Epithelial cell signaling in Helicobacter pylori infection GAB1 signalosome Phosphorylation of CD3 and TCR zeta chains +8 more
		CSMD1	Unknown	34062886	GWAS catalog	—
		CYP1A2	Unknown	28604730	GWAS catalog	Steroid hormone biosynthesis Caffeine metabolism Tryptophan metabolism +15 more
		CYP2A6	Unknown	28604730 34594039 35915169 37167549 37340002 38970920 39024449 39366959 40341939 40783572	ClinVar, GWAS catalog	Caffeine metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 +7 more
		CYP8B1	Unknown	35915169	GWAS catalog	Primary bile acid biosynthesis Metabolic pathways PPAR signaling pathway +7 more
		DAZL	Unknown	28604730	GWAS catalog	—
		DCAF4	Unknown	34290314	GWAS catalog	Neddylation
		DCBLD1	Unknown	23143601 34594039 35915169 37340002 40783572	GWAS catalog	—
		DDR1	Unknown	28604730	GWAS catalog	Non-integrin membrane-ECM interactions
		DLC1	Unknown	32887889	GWAS catalog	Rho GTPase cycle
		DLG2	Unknown	40341939	GWAS catalog	Hippo signaling pathway Tight junction Human papillomavirus infection +3 more
		DLGAP2	Unknown	28604730	GWAS catalog	—
		DLGAP4	Unknown	34290314	GWAS catalog	Neurexins and neuroligins
		DNAAF10	Unknown	32887889	GWAS catalog	—
		DNAJB4	Unknown	28604730 35915169	GWAS catalog	—
		DOCK8	Unknown	26732429	GWAS catalog	Factors involved in megakaryocyte development and platelet production
		DPEP1	Unknown	34290314	GWAS catalog	Synthesis of Leukotrienes (LT) and Eoxins (EX) Aflatoxin activation and detoxification LTC4-CYSLTR mediated IL4 production
		DPP6	Unknown	34290314	GWAS catalog	—
		DSP	Unknown	37340002	GWAS catalog	Cytoskeleton in muscle cells Arrhythmogenic right ventricular cardiomyopathy Apoptotic cleavage of cell adhesion proteins +3 more
		DTWD1	Unknown	28604730	GWAS catalog	—
LUNG CARCINOMA	EFO_0001071	CLK1	Unknown	34290314	GWAS catalog	Legionellosis
		CLPTM1L	Unknown	18978787 18978790 19654303 28604730 31009812 32887889 34290314 37340002 39366959	GWAS catalog	—
		CLSTN2	Unknown	28604730	GWAS catalog	—
		CLYBL	Unknown	34290314	GWAS catalog	—
		CMSS1	Unknown	32887889	GWAS catalog	—
		CNR1	Unknown	40341939	GWAS catalog	Rap1 signaling pathway Neuroactive ligand-receptor interaction Thermogenesis +3 more
		COL11A2	Unknown	28604730	GWAS catalog	Cytoskeleton in muscle cells Protein digestion and absorption Collagen degradation +5 more
		COL2A1	Unknown	27393504	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +14 more
		COL6A3	Unknown	28604730	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +11 more
		COL6A5	Unknown	28604730	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +11 more
		COL6A6	Unknown	28604730	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +11 more
		COPS2	Unknown	28604730 35915169 39366959	GWAS catalog	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis +1 more
		COPS8	Unknown	28604730	GWAS catalog	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis +1 more
		COX6C	Unknown	40829600	GWAS catalog	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction +12 more
		CRACD	Unknown	40341939	GWAS catalog	—
		CROT	Unknown	28604730	GWAS catalog	Peroxisome Beta-oxidation of pristanoyl-CoA Peroxisomal protein import
		CRP	Unknown	18385676	GWAS catalog	Classical antibody-mediated complement activation
		CSK	Unknown	28604730	GWAS catalog	Epithelial cell signaling in Helicobacter pylori infection GAB1 signalosome Phosphorylation of CD3 and TCR zeta chains +8 more
		CSMD1	Unknown	34062886	GWAS catalog	—
		CYBRD1	Unknown	32887889	GWAS catalog	Mineral absorption Iron uptake and transport
		CYP1A2	Unknown	28604730	GWAS catalog	Steroid hormone biosynthesis Caffeine metabolism Tryptophan metabolism +15 more
		CYP2A6	Unknown	28604730 34594039 35915169 37167549 37340002 38970920 39366959 40341939 40783572 40829600	GWAS catalog	Caffeine metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 +7 more
		CYP8B1	Unknown	35915169	GWAS catalog	Primary bile acid biosynthesis Metabolic pathways PPAR signaling pathway +7 more
		DAZL	Unknown	28604730	GWAS catalog	—
		DCAF4	Unknown	34290314	GWAS catalog	Neddylation
		DCBLD1	Unknown	23143601 34594039 35915169 37340002 37846649 40783572	GWAS catalog	—
		DDR1	Unknown	28604730	GWAS catalog	Non-integrin membrane-ECM interactions
		DLC1	Unknown	32887889	GWAS catalog	Rho GTPase cycle
		DLG2	Unknown	40341939	GWAS catalog	Hippo signaling pathway Tight junction Human papillomavirus infection +3 more
		DLGAP2	Unknown	28604730	GWAS catalog	—
		DLGAP4	Unknown	34290314	GWAS catalog	Neurexins and neuroligins
		DNAAF10	Unknown	32887889	GWAS catalog	—
		DNAJB4	Unknown	28604730 35915169	GWAS catalog	—
		DNAJC1	Unknown	32887889	GWAS catalog	Protein processing in endoplasmic reticulum
		DOCK8	Unknown	26732429	GWAS catalog	Factors involved in megakaryocyte development and platelet production
		DPEP1	Unknown	34290314	GWAS catalog	Synthesis of Leukotrienes (LT) and Eoxins (EX) Aflatoxin activation and detoxification LTC4-CYSLTR mediated IL4 production
		DPP6	Unknown	34290314	GWAS catalog	—
		DSP	Unknown	37340002	GWAS catalog	Cytoskeleton in muscle cells Arrhythmogenic right ventricular cardiomyopathy Apoptotic cleavage of cell adhesion proteins +3 more
		DTWD1	Unknown	28604730	GWAS catalog	—
		DVL1	Unknown	27197191	GWAS catalog	mTOR signaling pathway Wnt signaling pathway Notch signaling pathway +18 more
		EBF1	Unknown	32887889	GWAS catalog	—

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