Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
LUNG CANCER	MONDO_0008903 211980 MONDO:0008903	RIN3	Unknown	36819030	GWAS catalog	RAB GEFs exchange GTP for GDP on RABs
		SLC67A1	Unknown	12460919 9751628 22696596 15457249 16672372 15118125 16533793	ClinVar, HPO	—
		TRIM38	Unknown	36819030	GWAS catalog	Interferon gamma signaling
		ZKSCAN3	Unknown	36819030	GWAS catalog	Generic Transcription Pathway
		ZMIZ1	Unknown	36819030	GWAS catalog	—
LUNG CARCINOMA	EFO_0001071 MONDO:0005138	ACTRT2	Unknown	28604730	GWAS catalog	—
		ADARB2	Unknown	29924316	GWAS catalog	—
		ADCY8	Unknown	28604730	GWAS catalog	Purine metabolism Metabolic pathways Endocrine resistance +61 more
		AK9	Unknown	28604730	GWAS catalog	Purine metabolism Pyrimidine metabolism Metabolic pathways +3 more
		ALKAL1	Unknown	40829600	GWAS catalog	—
		ASB3	Unknown	30104567	GWAS catalog	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		ATRN	Unknown	37167549	GWAS catalog	—
		BRD9	Unknown	28604730	GWAS catalog	ATP-dependent chromatin remodeling
		BTN3A2	Unknown	28604730	GWAS catalog	Butyrophilin (BTN) family interactions
		C11ORF86	Unknown	29924316	GWAS catalog	—
		C15ORF39	Unknown	28604730	GWAS catalog	—
		C1S	Unknown	28604730	GWAS catalog	Complement and coagulation cascades Pertussis Staphylococcus aureus infection +5 more
		CACNA2D3	Unknown	28604730	GWAS catalog	MAPK signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +7 more
		CCDC50	Unknown	28604730	GWAS catalog	—
		CD3E	Unknown	28604730	GWAS catalog	Hematopoietic cell lineage Th1 and Th2 cell differentiation Th17 cell differentiation +14 more
		CDC14C	Unknown	28604730	GWAS catalog	Cell cycle
		CEP170	Unknown	28604730	GWAS catalog	—
		CLIP4	Unknown	28604730	GWAS catalog	—
		CRTAC1	Unknown	28604730	GWAS catalog	—
		CYP2A7	Unknown	40829600	GWAS catalog	Caffeine metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 +8 more
		DEPDC7	Unknown	28604730	GWAS catalog	Rho GTPase cycle
		DNAH11	Unknown	23103227	GWAS catalog	Motor proteins Amyotrophic lateral sclerosis Huntington disease +1 more
		DOK5	Unknown	30104567	GWAS catalog	RET signaling
		ERCC2	Unknown	23108145	GWAS catalog	Basal transcription factors Nucleotide excision repair Formation of RNA Pol II elongation complex +19 more
		EXOC2	Unknown	28604730	GWAS catalog	Ras signaling pathway Salmonella infection Insulin processing +1 more
		FASLG	Unknown	—	ClinVar	Platinum drug resistance MAPK signaling pathway Ras signaling pathway +38 more
		FHL2	Unknown	28604730	GWAS catalog	Osteoclast differentiation Cytoskeleton in muscle cells PPARA activates gene expression
		FUBP1	Unknown	28604730	GWAS catalog	—
		GALNT17	Unknown	28604730	GWAS catalog	Mucin type O-glycan biosynthesis Other types of O-glycan biosynthesis Metabolic pathways +1 more
		GNG2	Unknown	24658283	GWAS catalog	Ras signaling pathway Chemokine signaling pathway Hormone signaling +43 more
		GPATCH2	Unknown	29924316	GWAS catalog	—
		GRM7	Unknown	40829600	GWAS catalog	Phospholipase D signaling pathway Neuroactive ligand-receptor interaction Glutamatergic synapse +2 more
		H2AC6	Unknown	28604730	GWAS catalog	ATP-dependent chromatin remodeling Necroptosis Neutrophil extracellular trap formation +30 more
		HAPLN3	Unknown	28604730	GWAS catalog	—
		HMGN4	Unknown	28604730	GWAS catalog	—
		KCNMA1	Unknown	40829600	GWAS catalog	cGMP-PKG signaling pathway Vascular smooth muscle contraction Insulin secretion +4 more
		KIAA0753	Unknown	29924316	GWAS catalog	—
		LMNA	Unknown	28604730	GWAS catalog	Apoptosis Cytoskeleton in muscle cells Hypertrophic cardiomyopathy +8 more
		LRFN2	Unknown	23103227	GWAS catalog	Synaptic adhesion-like molecules
		MBD2	Unknown	29924316	GWAS catalog	ATP-dependent chromatin remodeling NoRC negatively regulates rRNA expression RNA Polymerase I Promoter Opening
		MBOAT2	Unknown	28604730	GWAS catalog	Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways +2 more
		MKLN1	Unknown	28604730	GWAS catalog	—
		MRPL32	Unknown	28604730	GWAS catalog	Ribosome Mitochondrial translation elongation Mitochondrial translation termination
		MSX2	Unknown	29924316	GWAS catalog	Human T-cell leukemia virus 1 infection
		NMBR	Unknown	29924316	GWAS catalog	Neuroactive ligand-receptor interaction Peptide ligand-binding receptors G alpha (q) signalling events

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Lung cancer

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