Subtype of: Breast cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
HER2 positive breast carcinoma	MONDO_0006244	MUC16	Unknown	27406316 20668451 22722202 33004031	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUC4	Unknown	28027327 21493686	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MYB	Unknown	22722202 25850943	Open Targets	PI3K-Akt signaling pathway RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression
		MYC	Unknown	30205045 25850943	Open Targets	MAPK signaling pathway ErbB signaling pathway Cell cycle +45 more
		MYCN	Unknown	25591616	Open Targets	Transcriptional misregulation in cancer
		MYD88	Unknown	20668451	Open Targets	MAPK signaling pathway NF-kappa B signaling pathway Toll-like receptor signaling pathway +39 more
		MYH11	Unknown	27406316 28027327 20668451	Open Targets	Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction +6 more
		MYH9	Unknown	27406316 25591616	Open Targets	Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction +8 more
		MYO5A	Unknown	22722202	Open Targets	Motor proteins Pathogenic Escherichia coli infection Regulation of actin dynamics for phagocytic cup formation +1 more
		N4BP2	Unknown	22722201	Open Targets	—
		NACA	Unknown	27406316	Open Targets	Parathyroid hormone synthesis, secretion and action
		NCOA1	Unknown	27406316 28027327 22722201	Open Targets	Estrogen signaling pathway Thyroid hormone signaling pathway Pathways in cancer +18 more
		NCOA2	Unknown	20668451	Open Targets	Estrogen signaling pathway Thyroid hormone signaling pathway RORA activates gene expression +14 more
		NCOR1	Unknown	30205045 22722201	Open Targets	Endocrine resistance TGF-beta signaling pathway Thyroid hormone signaling pathway +16 more
		NCOR2	Unknown	27406316 22722202	Open Targets	Notch signaling pathway Epstein-Barr virus infection PPARA activates gene expression +11 more
		NF1	Unknown	27406316 28027327 20668451	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +2 more
		NIN	Unknown	21493686	Open Targets	—
		NOTCH1	Unknown	25591616 22101766 20668451	Open Targets	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +20 more
		NOTCH2	Unknown	27406316 25591616 22722202	Open Targets	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +13 more
		NPM1	Unknown	27406316	Open Targets	Nuclear import of Rev protein SUMOylation of transcription cofactors Deposition of new CENPA-containing nucleosomes at the centromere +2 more
		NR4A3	Unknown	22722202	Open Targets	Transcriptional misregulation in cancer Nuclear Receptor transcription pathway RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
		NRG1	Unknown	27406316 22722202	Open Targets	EGFR tyrosine kinase inhibitor resistance ErbB signaling pathway Amyotrophic lateral sclerosis +18 more
		NSD1	Unknown	21493686 30205045 22722202	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		NSD3	Unknown	22722202	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		NT5C2	Unknown	27406316	Open Targets	Purine metabolism Pyrimidine metabolism Nicotinate and nicotinamide metabolism +4 more
		NTRK1	Unknown	27406316 22722202	Open Targets	MAPK signaling pathway Ras signaling pathway Calcium signaling pathway +13 more
		NTRK2	Unknown	38895905 22722202	Open Targets	MAPK signaling pathway Ras signaling pathway Calcium signaling pathway +6 more
		NTRK3	Unknown	28027327	Open Targets	Calcium signaling pathway Neurotrophin signaling pathway Central carbon metabolism in cancer +4 more
		NUMA1	Unknown	22722202	Open Targets	Recruitment of NuMA to mitotic centrosomes Mitotic Prophase
		NUP214	Unknown	20668451	Open Targets	Nucleocytoplasmic transport Amyotrophic lateral sclerosis ISG15 antiviral mechanism +26 more
		NUP98	Unknown	27406316 22722202	Open Targets	Nucleocytoplasmic transport Amyotrophic lateral sclerosis Influenza A +33 more
		OMD	Unknown	27406316	Open Targets	Keratan sulfate biosynthesis Keratan sulfate degradation Defective CHST6 causes MCDC1 +2 more
		PABPC1	Unknown	27406316	Open Targets	mRNA surveillance pathway RNA degradation L13a-mediated translational silencing of Ceruloplasmin expression +5 more
		PALB2	Unknown	27406316 28027327 20668451 30062102	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Homologous Recombination (HRR) +3 more
		PATZ1	Unknown	22722201	Open Targets	—
		PAX3	Unknown	27406316 28027327	Open Targets	Transcriptional misregulation in cancer HATs acetylate histones
		PBRM1	Unknown	27406316 33004031	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		PCBP1	Unknown	27406316	Open Targets	Spliceosome Ferroptosis Cytosolic DNA-sensing pathway +2 more
		PCM1	Unknown	20668451	Open Targets	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes +4 more
		PDE4DIP	Unknown	27406316	Open Targets	—
		PDGFRA	Unknown	25850943	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +30 more
		PDGFRB	Unknown	25850943	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +22 more
		PER1	Unknown	27406316 25591616	Open Targets	Circadian rhythm Circadian entrainment
		PIK3CA	Unknown	27406316 22722201 22172323 24416132 20616362 26527317 28750640 22454081 19372580 25850943 25757876 22744290 30062102 33004031 21512767 25056500 25467032 28027327 23601657 29807833 23982433 20668451 23665199 30205045 25591616 22722202	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +149 more
		PIK3CB	Unknown	20668451	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +126 more
		PIK3R1	Unknown	27406316 22722202	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +150 more
		PIK3R2	Unknown	38970069	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +129 more
		PLCG1	Unknown	25850943	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +70 more
		PLEC	Unknown	27406316 22722202	Open Targets	Cytoskeleton in muscle cells Assembly of collagen fibrils and other multimeric structures Caspase-mediated cleavage of cytoskeletal proteins +1 more
		PML	Unknown	27406316	Open Targets	Ubiquitin mediated proteolysis Endocytosis Influenza A +12 more

«‹1…3 456 7 8 ›»

Her2 positive breast carcinoma

Bookmark This Disease