Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
CARCINOMA, HEPATOCELLULAR	MESH:D006528	STMN1	Unknown	28284560	CTD	MAPK signaling pathway MicroRNAs in cancer Nuclear signaling by ERBB4
		TACC3	Unknown	28284560	CTD	—
		TAGLN2	Unknown	21472284	CTD	Platelet degranulation
		TALDO1	Unknown	19436114	CTD	Pentose phosphate pathway Metabolic pathways Carbon metabolism +6 more
		TATDN1	Unknown	21472284	CTD	—
		TCF19	Unknown	28284560	CTD	—
		TCIM	Unknown	28284560	CTD	—
		TEDC2	Unknown	28284560	CTD	—
		TERT	Unknown	16651430 22634754 25362482 25822088	CTD	Human papillomavirus infection Human T-cell leukemia virus 1 infection Pathways in cancer +4 more
		TFPI2	Unknown	17464989 28284560	CTD	—
		TGFA	Unknown	15565109 9029167	CTD	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway ErbB signaling pathway +31 more
		TGFB1	Unknown	9029167	CTD	MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway +49 more
		TGFB2	Unknown	33010264	CTD	MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway +30 more
		TGM3	Unknown	28284560	CTD	—
		TH	Unknown	21472284	CTD	Tyrosine metabolism Folate biosynthesis Metabolic pathways +7 more
		THEM4	Unknown	23392203	CTD	Fatty acid elongation Metabolic pathways PI3K-Akt signaling pathway +6 more
		THY1	Unknown	28284560	CTD	Leukocyte transendothelial migration Post-translational modification: synthesis of GPI-anchored proteins
		TICRR	Unknown	28284560	CTD	Cell cycle
		TIMD4	Unknown	28284560	CTD	Efferocytosis
		TK1	Unknown	28284560	CTD	Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways +2 more
		TLR4	Unknown	27022031	CTD	NF-kappa B signaling pathway HIF-1 signaling pathway Phagosome +41 more
		TLR7	Unknown	24990399	CTD	Neutrophil extracellular trap formation Toll-like receptor signaling pathway Measles +7 more
		TLR9	Unknown	24990399	CTD	Toll-like receptor signaling pathway Salmonella infection Chagas disease +12 more
		TMEM70	Unknown	27914986	CTD	—
		TNF	Unknown	27022031	CTD	Antifolate resistance MAPK signaling pathway Cytokine-cytokine receptor interaction +72 more
		TNFSF10	Unknown	17326159	CTD	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor FoxO signaling pathway +13 more
		TONSL	Unknown	28284560	CTD	—
		TOP2A	Unknown	28284560	CTD	Platinum drug resistance Transcription of E2F targets under negative control by DREAM complex SUMOylation of DNA replication proteins
		TP53	Unknown	17191126 18477611 22675488 25822088 8033108 9029167	CTD	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TPX2	Unknown	28284560	CTD	Regulation of TP53 Activity through Phosphorylation AURKA Activation by TPX2
		TRAIP	Unknown	28284560	CTD	Antigen processing: Ubiquitination & Proteasome degradation
		TRIM24	Unknown	18026104	CTD	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Signaling by BRAF and RAF fusions
		TRIP13	Unknown	28284560	CTD	Cell cycle
		TROAP	Unknown	28284560	CTD	—
		TSC1	Unknown	21499249	CTD	Phospholipase D signaling pathway Autophagy - animal mTOR signaling pathway +15 more
		TSLP	Unknown	28284560	CTD	Cytokine-cytokine receptor interaction JAK-STAT signaling pathway Interleukin-7 signaling
		TST	Unknown	21472284	CTD	Cysteine and methionine metabolism Sulfur metabolism Metabolic pathways +2 more
		TTC36	Unknown	28284560	CTD	—
		TTK	Unknown	28284560	CTD	Cell cycle
		TYMS	Unknown	18019677 18230555	CTD	Pyrimidine metabolism One carbon pool by folate Metabolic pathways +5 more
		UBD	Unknown	19363144	CTD	Neddylation
		UBE2C	Unknown	28284560	CTD	Ubiquitin mediated proteolysis Inactivation of APC/C via direct inhibition of the APC/C complex APC/C:Cdc20 mediated degradation of Cyclin B +15 more
		UBE2E2	Unknown	27914986	CTD	Ubiquitin mediated proteolysis Antigen processing: Ubiquitination & Proteasome degradation
		UBE2T	Unknown	28284560	CTD	Fanconi anemia pathway Fanconi Anemia Pathway Synthesis of active ubiquitin: roles of E1 and E2 enzymes
		UCHL1	Unknown	18666234	CTD	Parkinson disease Pathways of neurodegeneration - multiple diseases UCH proteinases
		UHRF1	Unknown	28284560	CTD	—
		UMPS	Unknown	18230555	CTD	Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways +2 more
		UROC1	Unknown	28284560	CTD	Histidine metabolism Metabolic pathways Histidine catabolism
		USP2	Unknown	21147110	CTD	TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway +2 more
		USP4	Unknown	35841383	CTD	TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway +1 more
HEPATOCELLULAR CARCINOMA	EFO_0000182	TGM3	Unknown	34290314 37340002	GWAS catalog	—

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Hepatocellular carcinoma

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