Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
HEPATOCELLULAR CARCINOMA	EFO_0000182	FARP1	Unknown	34290314	GWAS catalog	—
		FBRSL1	Unknown	34290314	GWAS catalog	Polycomb repressive complex
		FIGLA	Unknown	34290314	GWAS catalog	—
		FOXP1	Unknown	34290314	GWAS catalog	MicroRNAs in cancer Transcriptional regulation of pluripotent stem cells
		FRY	Unknown	27197191	GWAS catalog	—
		FXN	Unknown	29299148	GWAS catalog	Porphyrin metabolism Mitochondrial protein import Mitochondrial iron-sulfur cluster biogenesis
		GLB1	Unknown	21105107	GWAS catalog	Galactose metabolism Other glycan degradation Glycosaminoglycan degradation +11 more
		GOLPH3L	Unknown	34290314	GWAS catalog	—
		GPR137	Unknown	34290314	GWAS catalog	—
		GRHPR	Unknown	29299148	GWAS catalog	Glycine, serine and threonine metabolism Pyruvate metabolism Glyoxylate and dicarboxylate metabolism +2 more
		GRIK1	Unknown	22807686	GWAS catalog	Neuroactive ligand-receptor interaction Glutamatergic synapse Activation of Na-permeable kainate receptors +1 more
		GRM5	Unknown	34290314	GWAS catalog	Calcium signaling pathway Phospholipase D signaling pathway Neuroactive ligand-receptor interaction +10 more
		HLA-B	Unknown	27197191	GWAS catalog	Endocytosis Phagosome Cellular senescence +24 more
		HLA-DQA1	Unknown	22807686	GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HLA-DQB1	Unknown	23242368 27197191 28921602 33893285 34290314 37340002	GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HLA-DQB3	Unknown	21499248	GWAS catalog	—
		HLA-DRA	Unknown	34290314	GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HNF1B	Unknown	27197191 37340002	GWAS catalog	Maturity onset diabetes of the young
		HOXB13	Unknown	34290314	GWAS catalog	—
		IFNL3	Unknown	32514122 37340002	GWAS catalog	Cytokine-cytokine receptor interaction JAK-STAT signaling pathway Interleukin-20 family signaling
		IFNL4	Unknown	32514122	GWAS catalog	—
		IGF2BP2	Unknown	37340002	GWAS catalog	Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
		IRF4	Unknown	33893285 34290314	GWAS catalog	Th17 cell differentiation Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling +1 more
		JRK	Unknown	34290314 37340002	GWAS catalog	—
		KCNH1	Unknown	27197191	GWAS catalog	Voltage gated Potassium channels
		KCNQ1	Unknown	37340002	GWAS catalog	Adrenergic signaling in cardiomyocytes Cholinergic synapse Gastric acid secretion +6 more
		KIF1B	Unknown	20676096 29246937	GWAS catalog	Motor proteins COPI-dependent Golgi-to-ER retrograde traffic Kinesins
		KIF20B	Unknown	37340002	GWAS catalog	Motor proteins COPI-dependent Golgi-to-ER retrograde traffic Kinesins
		KRT5	Unknown	34290314	GWAS catalog	Type I hemidesmosome assembly Keratinization Formation of the cornified envelope
		LCTL	Unknown	34290314	GWAS catalog	—
		LDLRAD4	Unknown	34290314	GWAS catalog	—
		LRRIQ4	Unknown	34290314	GWAS catalog	—
		LY6K	Unknown	37340002	GWAS catalog	Post-translational modification: synthesis of GPI-anchored proteins
		MAP3K1	Unknown	37340002	GWAS catalog	MAPK signaling pathway Ubiquitin mediated proteolysis Tight junction +11 more
		MAU2	Unknown	35788059 37340002	GWAS catalog	Cell cycle Cohesin Loading onto Chromatin
		MCL1	Unknown	34290314	GWAS catalog	PI3K-Akt signaling pathway Apoptosis JAK-STAT signaling pathway +2 more
		MECOM	Unknown	27197191	GWAS catalog	Lysine degradation Metabolic pathways MAPK signaling pathway +4 more
		MLC1	Unknown	34290314	GWAS catalog	—
		MRPS11	Unknown	28662289	GWAS catalog	Ribosome Mitochondrial translation elongation Mitochondrial translation termination
		MRTFA	Unknown	37340002	GWAS catalog	SUMOylation of transcription cofactors RHO GTPases Activate Formins
		MTAP	Unknown	27197191	GWAS catalog	Cysteine and methionine metabolism Metabolic pathways Methionine salvage pathway +1 more
		MTX1	Unknown	27197191	GWAS catalog	Mitophagy - animal
		MYO9B	Unknown	34290314	GWAS catalog	Motor proteins Rho GTPase cycle Regulation of actin dynamics for phagocytic cup formation +2 more
		NCOA6	Unknown	34290314	GWAS catalog	RORA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis +4 more
		NHLRC1	Unknown	29299148	GWAS catalog	Ubiquitin mediated proteolysis Glycogen synthesis Myoclonic epilepsy of Lafora
		OBSCN	Unknown	37340002	GWAS catalog	Cytoskeleton in muscle cells NRAGE signals death through JNK Rho GTPase cycle +1 more
		OCA2	Unknown	34290314	GWAS catalog	Melanin biosynthesis
		OR6C6	Unknown	29299148	GWAS catalog	Olfactory transduction Olfactory Signaling Pathway
		PADI6	Unknown	34290314	GWAS catalog	Chromatin modifying enzymes
		PBX2	Unknown	37340002	GWAS catalog	—

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Hepatocellular carcinoma

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