Hepatocellular carcinoma

HATs acetylate histones Regulation of TP53 Degradation Regulation of TP53 Activity through Association with Co-factors Stabilization of p53 +1 more

Glycosylphosphatidylinositol (GPI)-anchor biosynthesis Metabolic pathways Attachment of GPI anchor to uPAR

Glycerolipid metabolism Metabolic pathways Acyl chain remodeling of DAG and TAG

Signaling pathways regulating pluripotency of stem cells

RMTs methylate histone arginines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

RMTs methylate histone arginines

Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation

Post-translational modification: synthesis of GPI-anchored proteins

Homologous recombination HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Presynaptic phase of homologous DNA pairing and strand exchange Factors involved in megakaryocyte development and platelet production +4 more

Spliceosome

Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation +3 more

Rho GTPase cycle Interleukin-4 and Interleukin-13 signaling

Antigen processing: Ubiquitination & Proteasome degradation

Mitophagy - animal

Apoptosis Apoptosis - multiple species Release of apoptotic factors from the mitochondria SMAC, XIAP-regulated apoptotic response +1 more

Neurotrophin signaling pathway Regulation of KIT signaling Factors involved in megakaryocyte development and platelet production

Melanin biosynthesis

Oocyte meiosis

TGF-beta signaling pathway Hippo signaling pathway Signaling by BMP Downregulation of TGF-beta receptor signaling SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Ub-specific processing proteases +3 more

Condensation of Prophase Chromosomes Condensation of Prometaphase Chromosomes

Telomere C-strand synthesis initiation

MAPK signaling pathway NF-kappa B signaling pathway Osteoclast differentiation Toll-like receptor signaling pathway NOD-like receptor signaling pathway IL-17 signaling pathway TNF signaling pathway Alcoholic liver disease Pathogenic Escherichia coli infection Shigellosis Salmonella infection Yersinia infection Leishmaniasis Toxoplasmosis Hepatitis B Measles Herpes simplex virus 1 infection Epstein-Barr virus infection Human immunodeficiency virus 1 infection Coronavirus disease - COVID-19 Lipid and atherosclerosis Nuclear signaling by ERBB4 NOD1/2 Signaling Pathway Downstream TCR signaling FCERI mediated NF-kB activation TAK1 activates NFkB by phosphorylation and activation of IKKs complex activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 TNFR1-induced NFkappaB signaling pathway CLEC7A (Dectin-1) signaling TICAM1,TRAF6-dependent induction of TAK1 complex Interleukin-1 signaling IRAK2 mediated activation of TAK1 complex TRAF6-mediated induction of TAK1 complex within TLR4 complex Alpha-protein kinase 1 signaling pathway IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation +33 more

Degradation of the extracellular matrix Collagen biosynthesis and modifying enzymes Anchoring fibril formation Crosslinking of collagen fibrils +1 more

GABAergic synapse

Antigen processing: Ubiquitination & Proteasome degradation

Interferon gamma signaling

Interferon gamma signaling

TRP channels

Tyrosine metabolism Metabolic pathways Melanogenesis Melanin biosynthesis +1 more

mTOR signaling pathway Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells Melanogenesis Cushing syndrome Alzheimer disease Pathways of neurodegeneration - multiple diseases Human papillomavirus infection Pathways in cancer Proteoglycans in cancer MicroRNAs in cancer Basal cell carcinoma Breast cancer Hepatocellular carcinoma Gastric cancer TCF dependent signaling in response to WNT WNT ligand biogenesis and trafficking Disassembly of the destruction complex and recruitment of AXIN to the membrane Regulation of FZD by ubiquitination RNF mutants show enhanced WNT signaling and proliferation +18 more