Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
HEART FAILURE	EFO_0003144 C0018801 MESH:D006333	KLB	Unknown	40195560	GWAS catalog	Thermogenesis PI3K Cascade PIP3 activates AKT signaling +9 more
		KLHDC8B	Unknown	36376295	GWAS catalog	—
		KLHL3	Unknown	31919418 36376295 37429843 40195560 41184235	GWAS catalog	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		KY	Unknown	36376295	GWAS catalog	—
		LIPC	Unknown	27790247	GWAS catalog	Glycerolipid metabolism Metabolic pathways Cholesterol metabolism +2 more
		LMF1	Unknown	36376295	GWAS catalog	Assembly of active LPL and LIPC lipase complexes
		LOXL4	Unknown	40195560	GWAS catalog	Elastic fibre formation Crosslinking of collagen fibrils
		LPA	Unknown	31919418 33910581 36376295 36777996 37429843 39024449 40195560 41184235	GWAS catalog	Cholesterol metabolism
		LPL	Unknown	27790247 40195560	GWAS catalog	Glycerolipid metabolism PPAR signaling pathway Cholesterol metabolism +5 more
		LRFN2	Unknown	40195560	GWAS catalog	Synaptic adhesion-like molecules
		LRIG3	Unknown	20445134	GWAS catalog	—
		LRRC10	Unknown	36071497	CTD, Disgenet	—
		LRRC37A	Unknown	40195560	GWAS catalog	—
		LSM3	Unknown	36376295	GWAS catalog	RNA degradation Spliceosome mRNA decay by 5' to 3' exoribonuclease +1 more
		LSP1	Unknown	40195560	GWAS catalog	C-type lectin receptor signaling pathway Tuberculosis
		MAD1L1	Unknown	40465716	GWAS catalog	Cell cycle Oocyte meiosis Progesterone-mediated oocyte maturation +8 more
		MAGI3	Unknown	40195560	GWAS catalog	Rap1 signaling pathway
		MAML3	Unknown	27790247 40195560	GWAS catalog	Notch signaling pathway Th1 and Th2 cell differentiation Human papillomavirus infection +9 more
		MAP2K1	Unknown	36071497	CTD, Disgenet	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +99 more
		MAP2K5	Unknown	40195560	GWAS catalog	MAPK signaling pathway Gap junction Neurotrophin signaling pathway +2 more
		MAP2K7	Unknown	21284947	CTD, Disgenet	MAPK signaling pathway ErbB signaling pathway Protein processing in endoplasmic reticulum +26 more
		MAP3K7CL	Unknown	39024449 40195560	GWAS catalog	—
		MAPK10	Unknown	36071497	CTD, Disgenet	Endocrine resistance MAPK signaling pathway ErbB signaling pathway +74 more
		MAPK7	Unknown	40195560	GWAS catalog	MAPK signaling pathway Gap junction IL-17 signaling pathway +11 more
		MAPT	Unknown	36376295	GWAS catalog	MAPK signaling pathway Alzheimer disease Parkinson disease +2 more
		MECOM	Unknown	40195560	GWAS catalog	Lysine degradation Metabolic pathways MAPK signaling pathway +4 more
		MEF2D	Unknown	40195560	GWAS catalog	cGMP-PKG signaling pathway Apelin signaling pathway Parathyroid hormone synthesis, secretion and action +4 more
		MEI4	Unknown	36376295 40195560 41184235	GWAS catalog	—
		MIA3	Unknown	37429843 40195560	GWAS catalog	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Cargo concentration in the ER Post-translational protein phosphorylation
		MLF1	Unknown	40195560	GWAS catalog	Transcriptional misregulation in cancer
		MLIP	Unknown	36376295 40195560	GWAS catalog	—
		MLXIPL	Unknown	27790247	GWAS catalog	Insulin resistance Non-alcoholic fatty liver disease PKA-mediated phosphorylation of key metabolic factors +1 more
		MMP1	Unknown	—	Disgenet	PPAR signaling pathway IL-17 signaling pathway Relaxin signaling pathway +11 more
		MSTN	Unknown	16968467	CTD, Disgenet	Cytokine-cytokine receptor interaction
		MTHFD2	Unknown	36071497	CTD, Disgenet	One carbon pool by folate Metabolic pathways Biosynthesis of cofactors +1 more
		MX1	Unknown	27790247 36071497	CTD, Disgenet, GWAS catalog	Viral life cycle - HIV-1 Hepatitis C Measles +5 more
		MYH11	Unknown	40195560	GWAS catalog	Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction +6 more
		MYH7	Unknown	—	Disgenet	cGMP-PKG signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +6 more
		MYO1C	Unknown	36376295	GWAS catalog	Motor proteins Pathogenic Escherichia coli infection Regulation of actin dynamics for phagocytic cup formation +2 more
		MYOC	Unknown	36071497	CTD, Disgenet	—
		NEBL	Unknown	41184235	GWAS catalog	Cytoskeleton in muscle cells
		NEDD4L	Unknown	36376295	GWAS catalog	Ubiquitin mediated proteolysis Endocytosis Tight junction +5 more
		NFAT5	Unknown	37429843 40195560	GWAS catalog	—
		NFE2L2	Unknown	28373008	CTD, Disgenet	Protein processing in endoplasmic reticulum Parkinson disease Pathways in cancer +4 more
		NFIA	Unknown	36376295 40195560 41184235	GWAS catalog	—
		NISCH	Unknown	—	Disgenet	—
		NOS2	Unknown	19168511	CTD, Disgenet	Arginine biosynthesis Arginine and proline metabolism Metabolic pathways +21 more
		NOS3	Unknown	19168511 20304815 40195560	CTD, Disgenet, GWAS catalog	Arginine biosynthesis Arginine and proline metabolism Metabolic pathways +24 more
		NOX1	Unknown	20304815	CTD, Disgenet	Osteoclast differentiation AGE-RAGE signaling pathway in diabetic complications Alzheimer disease +6 more
		NOX4	Unknown	20304815	CTD, Disgenet	AGE-RAGE signaling pathway in diabetic complications Alcoholic liver disease Alzheimer disease +3 more
HEART FAILURE, DIASTOLIC	C1135196 MESH:D054144	MYH7	Unknown	29556499	CTD, Disgenet	cGMP-PKG signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +6 more

«‹1…3 456 7…10 ›»

Heart failure

Bookmark This Disease