Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
gastric adenoma	MONDO_0006221	KAT6B	Unknown	29945994	Open Targets	HATs acetylate histones
		KCNJ5	Unknown	27175599 29945994	Open Targets	Circadian entrainment Retrograde endocannabinoid signaling Serotonergic synapse +8 more
		KDM5A	Unknown	29945994	Open Targets	HDMs demethylate histones
		KDM6A	Unknown	27175599 29945994	Open Targets	Transcriptional misregulation in cancer HDMs demethylate histones
		KDR	Unknown	27175599 29945994	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +13 more
		KIAA1549	Unknown	29945994	Open Targets	Signaling by BRAF and RAF fusions
		KIF5B	Unknown	29945994	Open Targets	Endocytosis Dopaminergic synapse Motor proteins +12 more
		KIT	Unknown	29945994	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +15 more
		KLK2	Unknown	27175599	Open Targets	Renin-angiotensin system Endocrine and other factor-regulated calcium reabsorption Activation of Matrix Metalloproteinases +2 more
		KMT2A	Unknown	27175599 29945994	Open Targets	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KMT2C	Unknown	27175599 29945994	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		KMT2D	Unknown	27175599 29945994	Open Targets	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KNL1	Unknown	27175599 29945994	Open Targets	Cell cycle Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids +5 more
		KRAS	Unknown	27175599 26421956 12920223 12163385 2049776 23404616 8387955 23208952 1902452 25832318 9058292 29945994 10980114	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		LARP4B	Unknown	27175599 29945994	Open Targets	—
		LATS1	Unknown	29945994	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo
		LATS2	Unknown	29945994	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo
		LCK	Unknown	29945994	Open Targets	NF-kappa B signaling pathway Osteoclast differentiation Natural killer cell mediated cytotoxicity +27 more
		LIFR	Unknown	29945994	Open Targets	Cytokine-cytokine receptor interaction Signaling pathways regulating pluripotency of stem cells JAK-STAT signaling pathway +2 more
		LMNA	Unknown	27175599 29945994	Open Targets	Apoptosis Cytoskeleton in muscle cells Hypertrophic cardiomyopathy +8 more
		LOC124905021	Unknown	27175599	Open Targets	—
		LRIG3	Unknown	29945994	Open Targets	—
		LRP1B	Unknown	27175599 29945994	Open Targets	—
		LZTR1	Unknown	29945994	Open Targets	—
		MACC1	Unknown	27175599	Open Targets	—
		MAF	Unknown	29945994	Open Targets	Th1 and Th2 cell differentiation Transcriptional misregulation in cancer Inflammatory bowel disease
		MAFB	Unknown	29945994	Open Targets	Parathyroid hormone synthesis, secretion and action
		MAML2	Unknown	27175599	Open Targets	Notch signaling pathway Th1 and Th2 cell differentiation Human papillomavirus infection +9 more
		MAP2K1	Unknown	29945994	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +99 more
		MAP2K4	Unknown	29945994	Open Targets	MAPK signaling pathway ErbB signaling pathway Toll-like receptor signaling pathway +21 more
		MAP3K1	Unknown	29945994	Open Targets	MAPK signaling pathway Ubiquitin mediated proteolysis Tight junction +11 more
		MAP3K13	Unknown	27175599	Open Targets	MAPK signaling pathway
		MAPK1	Unknown	29945994	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +161 more
		MAX	Unknown	27175599 29945994	Open Targets	Polycomb repressive complex MAPK signaling pathway Pathways in cancer +6 more
		MB21D2	Unknown	27175599 29945994	Open Targets	—
		MDM2	Unknown	29945994	Open Targets	Endocrine resistance Platinum drug resistance FoxO signaling pathway +35 more
		MDM4	Unknown	27175599	Open Targets	p53 signaling pathway MicroRNAs in cancer Oxidative Stress Induced Senescence +6 more
		MED12	Unknown	27175599	Open Targets	Thyroid hormone signaling pathway PPARA activates gene expression Generic Transcription Pathway +1 more
		MET	Unknown	27175599 29945994	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +37 more
		MITF	Unknown	29945994	Open Targets	Mitophagy - animal Osteoclast differentiation Melanogenesis +4 more
		MLF1	Unknown	29945994	Open Targets	Transcriptional misregulation in cancer
		MLH1	Unknown	27175599 29945994	Open Targets	Platinum drug resistance Mismatch repair Fanconi anemia pathway +8 more
		MN1	Unknown	27175599 29945994	Open Targets	—
		MSH2	Unknown	27175599 29945994	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +7 more
		MTOR	Unknown	29945994	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +61 more
		MUC16	Unknown	27175599 29945994	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUC4	Unknown	27175599 29945994	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUC6	Unknown	27175599 29945994	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MYB	Unknown	29945994	Open Targets	PI3K-Akt signaling pathway RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression
		MYC	Unknown	29945994	Open Targets	MAPK signaling pathway ErbB signaling pathway Cell cycle +45 more

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Gastric adenoma

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