Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
gastric adenoma	MONDO_0006221	A1CF	Unknown	29945994	Open Targets	mRNA Editing: C to U Conversion Formation of the Editosome
		ABL1	Unknown	29945994	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		ACKR3	Unknown	27175599	Open Targets	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine receptors bind chemokines +1 more
		ACSL6	Unknown	27175599 29945994	Open Targets	Fatty acid biosynthesis Fatty acid degradation Metabolic pathways +7 more
		ACVR1B	Unknown	27175599	Open Targets	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +1 more
		ACVR2A	Unknown	27175599 29945994	Open Targets	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +3 more
		AFDN	Unknown	29945994	Open Targets	Ras signaling pathway Rap1 signaling pathway cAMP signaling pathway +4 more
		AFF3	Unknown	29945994	Open Targets	—
		AKAP9	Unknown	29945994	Open Targets	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes +7 more
		ALK	Unknown	29945994	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		AMER1	Unknown	29945994	Open Targets	Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade Disassembly of the destruction complex and recruitment of AXIN to the membrane +8 more
		ANK1	Unknown	27175599 29945994	Open Targets	Proteoglycans in cancer Interaction between L1 and Ankyrins Neurofascin interactions +1 more
		APC	Unknown	27175599 7606737 12920223 16760271 25832318 8242071 8118796 12414520 22287596 15494708 29945994 22741528 10980114	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		AR	Unknown	29945994	Open Targets	Oocyte meiosis Pathways in cancer Chemical carcinogenesis - receptor activation +7 more
		ARAF	Unknown	29945994	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +41 more
		ARHGAP26	Unknown	29945994	Open Targets	Rho GTPase cycle
		ARHGAP5	Unknown	29945994	Open Targets	Focal adhesion Leukocyte transendothelial migration Rho GTPase cycle
		ARHGEF10	Unknown	27175599 29945994	Open Targets	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
		ARHGEF10L	Unknown	27175599 29945994	Open Targets	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
		ARHGEF12	Unknown	27175599 29945994	Open Targets	Vascular smooth muscle contraction Axon guidance Platelet activation +12 more
		ARID1A	Unknown	29945994	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID2	Unknown	27175599 29945994	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		ASPM	Unknown	29945994	Open Targets	—
		ASPSCR1	Unknown	27175599 29945994	Open Targets	Transcriptional misregulation in cancer
		ASXL1	Unknown	29945994	Open Targets	Polycomb repressive complex UCH proteinases
		ASXL2	Unknown	29945994	Open Targets	Polycomb repressive complex UCH proteinases
		ATM	Unknown	27175599 29945994	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		ATR	Unknown	29945994	Open Targets	Fanconi anemia pathway Cell cycle p53 signaling pathway +13 more
		ATRX	Unknown	29945994	Open Targets	Cell cycle
		AXIN1	Unknown	29945994	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		AXIN2	Unknown	29945994	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +15 more
		BAP1	Unknown	29945994	Open Targets	Polycomb repressive complex UCH proteinases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
		BARD1	Unknown	27175599	Open Targets	Homologous recombination HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) +11 more
		BAX	Unknown	29945994 10653003	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +52 more
		BCL11A	Unknown	29945994	Open Targets	—
		BCL11B	Unknown	27175599 29945994	Open Targets	Transcriptional misregulation in cancer
		BCL2	Unknown	27175599	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +46 more
		BCL2L12	Unknown	29945994	Open Targets	—
		BCL6	Unknown	29945994	Open Targets	FoxO signaling pathway Transcriptional misregulation in cancer Chemical carcinogenesis - receptor activation +3 more
		BCL9	Unknown	29945994	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCL9L	Unknown	27175599 29945994	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCOR	Unknown	29945994	Open Targets	Polycomb repressive complex
		BCORL1	Unknown	29945994	Open Targets	Polycomb repressive complex
		BCR	Unknown	29945994	Open Targets	Pathways in cancer Chronic myeloid leukemia Signaling by cytosolic FGFR1 fusion mutants +2 more
		BLM	Unknown	27175599 29945994	Open Targets	Homologous recombination Fanconi anemia pathway Processive synthesis on the C-strand of the telomere +10 more
		BRAF	Unknown	29945994	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA2	Unknown	27175599 29945994	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BRD3	Unknown	29945994	Open Targets	—
		BRD4	Unknown	27175599 29945994	Open Targets	—
		BRIP1	Unknown	27175599 29945994	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +8 more

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Gastric adenoma

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