Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
CROHN'S DISEASE	EFO_0000384	DCBLD1	Unknown	37156999	GWAS catalog	—
		DCTD	Unknown	26301688	GWAS catalog	Pyrimidine metabolism Metabolic pathways Nucleotide metabolism +1 more
		DENND3	Unknown	37156999	GWAS catalog	RAB GEFs exchange GTP for GDP on RABs
		DGKH	Unknown	37156999	GWAS catalog	Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways +4 more
		DHX35	Unknown	39024449	GWAS catalog	—
		DLD	Unknown	26192919 26974007 28067908 33608531 37156999	GWAS catalog	Glycolysis / Gluconeogenesis Citrate cycle (TCA cycle) Glycine, serine and threonine metabolism +20 more
		DMRTA1	Unknown	30801121	GWAS catalog	—
		DNMT3B	Unknown	23128233 26192919 26974007	GWAS catalog	Cysteine and methionine metabolism Metabolic pathways MicroRNAs in cancer +2 more
		DOCK7	Unknown	26192919 28067908	GWAS catalog	MET activates RAP1 and RAC1 Factors involved in megakaryocyte development and platelet production
		DOCK8	Unknown	37156999	GWAS catalog	Factors involved in megakaryocyte development and platelet production
		DPH5	Unknown	26192919	GWAS catalog	Synthesis of diphthamide-EEF2
		DR1	Unknown	37156999	GWAS catalog	—
		DTNB	Unknown	35232999	GWAS catalog	—
		DUSP16	Unknown	23128233 26192919	GWAS catalog	MAPK signaling pathway Efferocytosis RAF-independent MAPK1/3 activation +2 more
		DUSP22	Unknown	26192919 37156999	GWAS catalog	—
		DUSP29	Unknown	28008999	GWAS catalog	—
		DUSP7	Unknown	37156999	GWAS catalog	MAPK signaling pathway Efferocytosis RAF-independent MAPK1/3 activation +2 more
		EBLN1	Unknown	38616254	GWAS catalog	—
		EEF1AKMT2	Unknown	28067908 37156999	GWAS catalog	Protein methylation
		EFEMP2	Unknown	37156999	GWAS catalog	Molecules associated with elastic fibres
		ELAC1	Unknown	37156999	GWAS catalog	—
		ELF1	Unknown	23266558 37156999	GWAS catalog	RUNX1 regulates transcription of genes involved in BCR signaling RUNX1 regulates transcription of genes involved in interleukin signaling
		ELL	Unknown	37156999	GWAS catalog	Viral life cycle - HIV-1 Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events +4 more
		ELMO1	Unknown	37156999	GWAS catalog	Chemokine signaling pathway Efferocytosis Bacterial invasion of epithelial cells +8 more
		ELP6	Unknown	39024449	GWAS catalog	—
		EMSY	Unknown	18587394 21102463 23128233 26192919 26974007 28067908 33608531 33686288 37156999 37262302	GWAS catalog	—
		EPHB4	Unknown	26192919	GWAS catalog	Axon guidance EPH-Ephrin signaling EPHB-mediated forward signaling +2 more
		EPO	Unknown	23128233 37156999	GWAS catalog	Cytokine-cytokine receptor interaction HIF-1 signaling pathway Hormone signaling +8 more
		ERAP1	Unknown	26974007	GWAS catalog	Antigen Presentation: Folding, assembly and peptide loading of class I MHC
		ERBB3	Unknown	37156999	GWAS catalog	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway ErbB signaling pathway +19 more
		ERGIC1	Unknown	26192919 28067908 37156999	GWAS catalog	—
		ERN1	Unknown	26974007	GWAS catalog	Autophagy - animal Protein processing in endoplasmic reticulum Apoptosis +9 more
		ETS1	Unknown	26974007 28067908 37156999	GWAS catalog	Ras signaling pathway Cellular senescence Human T-cell leukemia virus 1 infection +3 more
		EXOC6	Unknown	26192919	GWAS catalog	Insulin processing VxPx cargo-targeting to cilium
		F5	Unknown	26192919 37156999	GWAS catalog	Complement and coagulation cascades Platelet degranulation Common Pathway of Fibrin Clot Formation +4 more
		FADS1	Unknown	37156999	GWAS catalog	Biosynthesis of unsaturated fatty acids Metabolic pathways Fatty acid metabolism +3 more
		FADS2	Unknown	23128233 26192919 28067908 37156999 38154582	GWAS catalog	alpha-Linolenic acid metabolism Biosynthesis of unsaturated fatty acids Metabolic pathways +4 more
		FAM118A	Unknown	26974007	GWAS catalog	—
		FAM177A1	Unknown	26974007	GWAS catalog	—
		FAM216B	Unknown	37156999	GWAS catalog	—
		FAP	Unknown	23128233 26974007 37156999	GWAS catalog	—
		FAS	Unknown	26974007	GWAS catalog	Platinum drug resistance MAPK signaling pathway Cytokine-cytokine receptor interaction +36 more
		FCAR	Unknown	23128233 37156999	GWAS catalog	Phagosome Staphylococcus aureus infection Neutrophil degranulation
		FCGR2A	Unknown	23128233 26192919 26974007 28067908 33608531 37156999	GWAS catalog	Phagosome Osteoclast differentiation Platelet activation +14 more
		FCHSD2	Unknown	23266558 23850713 37156999	GWAS catalog	—
		FEN1	Unknown	23128233 28067908	GWAS catalog	DNA replication Base excision repair Non-homologous end-joining +6 more
		FERMT1	Unknown	28067908 37156999	GWAS catalog	—
		FIBP	Unknown	23128233 26192919 26974007	GWAS catalog	—
		FKBP8	Unknown	37156999	GWAS catalog	Mitophagy - animal Ub-specific processing proteases
		FNBP1	Unknown	26301688	GWAS catalog	Shigellosis Clathrin-mediated endocytosis
CROHNS DISEASE OF LARGE BOWEL	C0156147	FCGR2A	Unknown	—	Disgenet	Phagosome Osteoclast differentiation Platelet activation +14 more

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Crohn disease

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