Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
COLONIC NEOPLASMS	MESH:D003110	PCNA	Unknown	19028472 19723570	CTD	DNA replication Base excision repair Nucleotide excision repair +29 more
		PCP4	Unknown	15059925	CTD	—
		PLCB1	Unknown	15059925	CTD	Inositol phosphate metabolism Metabolic pathways Rap1 signaling pathway +67 more
		PLXDC1	Unknown	39267413	CTD	—
		POLB	Unknown	25030372	CTD	Base excision repair Human T-cell leukemia virus 1 infection Viral carcinogenesis +7 more
		PPARG	Unknown	20540935	CTD	PPAR signaling pathway Efferocytosis AMPK signaling pathway +13 more
		PRKN	Unknown	19946270	CTD	Ubiquitin mediated proteolysis Mitophagy - animal Protein processing in endoplasmic reticulum +8 more
		PROM1	Unknown	21188121	CTD	Transcriptional misregulation in cancer
		PRR5-ARHGAP8	Unknown	25279216	CTD	—
		PTGS2	Unknown	12189188 17667525 21081470	CTD	Arachidonic acid metabolism Metabolic pathways NF-kappa B signaling pathway +29 more
		PTP4A3	Unknown	23555575	CTD	—
		RCOR1	Unknown	25043185	CTD	Huntington disease HDACs deacetylate histones Factors involved in megakaryocyte development and platelet production
		RECK	Unknown	17443689	CTD	MicroRNAs in cancer Post-translational modification: synthesis of GPI-anchored proteins
		RELA	Unknown	20715105	CTD	Antifolate resistance MAPK signaling pathway Ras signaling pathway +95 more
		RFC1	Unknown	18926688	CTD	DNA replication Base excision repair Nucleotide excision repair +15 more
		RHOJ	Unknown	15059925	CTD	Salmonella infection Rho GTPase cycle
		RNF34	Unknown	16270526	CTD	Regulation of TP53 Degradation Antigen processing: Ubiquitination & Proteasome degradation
		S100A4	Unknown	21685359	CTD	—
		S100A9	Unknown	15059925	CTD	IL-17 signaling pathway RHO GTPases Activate NADPH Oxidases Regulation of TLR by endogenous ligand +2 more
		SERPINB5	Unknown	15059925	CTD	p53 signaling pathway MicroRNAs in cancer
		SERTAD1	Unknown	18097604	CTD	—
		SH3KBP1	Unknown	15059925	CTD	Endocytosis EGFR downregulation Negative regulation of MET activity +4 more
		SLC16A1	Unknown	11953883	CTD	Efferocytosis Basigin interactions Proton-coupled monocarboxylate transport +2 more
		SLC19A1	Unknown	15705887	CTD	Antifolate resistance Vitamin digestion and absorption Folate transport and metabolism +1 more
		SLC22A1	Unknown	15059925	CTD	Bile secretion Choline metabolism in cancer Neurotransmitter clearance +4 more
		SLC2A1	Unknown	11953883	CTD	HIF-1 signaling pathway Efferocytosis Insulin secretion +15 more
		SLC5A8	Unknown	15090606 16670197	CTD	Nicotinamide salvaging Organic anion transporters
		SLCO1B3	Unknown	22326869 25625007	CTD	Bile secretion Folate transport and metabolism Recycling of bile acids and salts +3 more
		SOD2	Unknown	25279216	CTD	FoxO signaling pathway Peroxisome Longevity regulating pathway +9 more
		SPARC	Unknown	17397030	CTD	Platelet degranulation Nuclear signaling by ERBB4 ECM proteoglycans +1 more
		SRC	Unknown	14569062	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +92 more
		STAT3	Unknown	19028472	CTD	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway HIF-1 signaling pathway +53 more
		SULT1A1	Unknown	15059925	CTD	Chemical carcinogenesis - DNA adducts Cytosolic sulfonation of small molecules
		TAGLN	Unknown	15059925	CTD	—
		TCF19	Unknown	15059925	CTD	—
		TCF7L2	Unknown	21383188	CTD	Wnt signaling pathway Hippo signaling pathway Adherens junction +26 more
		TGFBR2	Unknown	7761852	CTD	MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway +28 more
		TNF	Unknown	12842827 19028472	CTD	Antifolate resistance MAPK signaling pathway Cytokine-cytokine receptor interaction +72 more
		TNFRSF10A	Unknown	17075118	CTD	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor p53 signaling pathway +15 more
		TNFRSF9	Unknown	25279216	CTD	Cytokine-cytokine receptor interaction TNFs bind their physiological receptors
		TNFSF10	Unknown	15993848	CTD	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor FoxO signaling pathway +13 more
		TP53	Unknown	17075118 17192441 26192916	CTD	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TP53BP1	Unknown	30705370	CTD	NOD-like receptor signaling pathway SUMOylation of transcription factors Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks +3 more
		TPM3	Unknown	19369484	CTD	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +7 more
		TRMT11	Unknown	30705370	CTD	—
		TYMP	Unknown	18652704	CTD	Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways +4 more
		TYMS	Unknown	15355913 16284371 16609021 18192902 18652704 19105824	CTD	Pyrimidine metabolism One carbon pool by folate Metabolic pathways +5 more
		UMPS	Unknown	18652704	CTD	Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways +2 more
		USP39	Unknown	34822033	CTD	Spliceosome mRNA Splicing - Major Pathway
		VEGFA	Unknown	18987561	CTD	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +30 more

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Colonic neoplasms

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