Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
COLONIC NEOPLASMS	MESH:D003110	ACTG2	Unknown	15059925	CTD	Vascular smooth muscle contraction Motor proteins Cytoskeleton in muscle cells +1 more
		ALDH1B1	Unknown	25641190	CTD	Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid degradation +13 more
		ALOX12B	Unknown	30258081	CTD	Arachidonic acid metabolism Metabolic pathways Serotonergic synapse +1 more
		ALOX5	Unknown	14569062 18927292 30258081	CTD	Arachidonic acid metabolism Metabolic pathways Efferocytosis +19 more
		APC	Unknown	10383901 12034317 17192441 24431404 25200834 26335331 35362542 7846077 8608549	CTD	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		ASCL2	Unknown	15059925	CTD	—
		ATP7A	Unknown	17510416	CTD	Platinum drug resistance Mineral absorption Ion influx/efflux at host-pathogen interface +1 more
		AXIN2	Unknown	21188121	CTD	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +15 more
		BAK1	Unknown	18349538	CTD	Platinum drug resistance Protein processing in endoplasmic reticulum Apoptosis +32 more
		BAP1	Unknown	25231345	CTD	Polycomb repressive complex UCH proteinases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
		BAX	Unknown	17404573	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +52 more
		BCL2	Unknown	10223192 17404573 19147571	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +46 more
		BECN1	Unknown	20876807	CTD	Autophagy - other Mitophagy - animal Autophagy - animal +11 more
		BIRC5	Unknown	16224667 19147571	CTD	Platinum drug resistance Apoptosis Apoptosis - multiple species +15 more
		BRD4	Unknown	26752646	CTD	—
		CACNA2D1	Unknown	15059925	CTD	MAPK signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +7 more
		CBR1	Unknown	21056497	CTD	Arachidonic acid metabolism Folate biosynthesis Metabolism of xenobiotics by cytochrome P450 +4 more
		CCL20	Unknown	15059925	CTD	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +6 more
		CCL3	Unknown	36346222	CTD	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +7 more
		CCND1	Unknown	18283038 19147571 21081470 21188121	CTD	Endocrine resistance FoxO signaling pathway Cell cycle +58 more
		CCND2	Unknown	15059925	CTD	FoxO signaling pathway Cell cycle p53 signaling pathway +18 more
		CCNH	Unknown	30705370	CTD	Basal transcription factors Nucleotide excision repair Cell cycle +24 more
		CCR1	Unknown	36346222	CTD	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +5 more
		CCR5	Unknown	36346222	CTD	Viral life cycle - HIV-1 Virion - Human immunodeficiency virus Cytokine-cytokine receptor interaction +12 more
		CDKN1A	Unknown	20876807	CTD	Endocrine resistance Platinum drug resistance ErbB signaling pathway +56 more
		CDX2	Unknown	29439001	CTD	Gastric cancer Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
		CKM	Unknown	15059925	CTD	Arginine and proline metabolism Metabolic pathways Cytoskeleton in muscle cells +1 more
		CP	Unknown	23792645	CTD	Porphyrin metabolism Ferroptosis Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) +5 more
		CRYAB	Unknown	15059925	CTD	Protein processing in endoplasmic reticulum Longevity regulating pathway - multiple species HSF1-dependent transactivation
		CTNNB1	Unknown	12628520 12800193 14507667 15459021 17404573 18283038 21081470 22323126 9515794	CTD	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		CXCL10	Unknown	15059925	CTD	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +12 more
		CYP26A1	Unknown	16885356	CTD	Retinol metabolism Metabolic pathways Vitamins +1 more
		DEFA5	Unknown	15844706	CTD	NOD-like receptor signaling pathway Staphylococcus aureus infection Transcriptional misregulation in cancer +2 more
		DMBT1	Unknown	15059925	CTD	Salivary secretion Surfactant metabolism
		DNMT1	Unknown	19723570	CTD	Cysteine and methionine metabolism Metabolic pathways MicroRNAs in cancer +2 more
		DPYD	Unknown	18652704	CTD	Pyrimidine metabolism beta-Alanine metabolism Pantothenate and CoA biosynthesis +3 more
		EGFR	Unknown	14569062 25200834	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Virion - Hepatitis viruses +79 more
		EIF3I	Unknown	24056964	CTD	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits +3 more
		EOMES	Unknown	27539959	CTD	—
		ERBB2	Unknown	11222871	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +48 more
		F5	Unknown	25200834	CTD	Complement and coagulation cascades Platelet degranulation Common Pathway of Fibrin Clot Formation +4 more
		FBP1	Unknown	22039417	CTD	Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism +6 more
		FOLR1	Unknown	15705887 18926688	CTD	Antifolate resistance Endocytosis Folate transport and metabolism +3 more
		FZD2	Unknown	21188121	CTD	mTOR signaling pathway Wnt signaling pathway Hippo signaling pathway +16 more
		GAP43	Unknown	15059925	CTD	L1CAM interactions
		GAST	Unknown	3952654	CTD	Hormone signaling Gastric acid secretion G alpha (q) signalling events +1 more
		GCG	Unknown	22323126	CTD	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +11 more
		GRIK2	Unknown	30705370	CTD	Neuroactive ligand-receptor interaction Glutamatergic synapse Activation of Na-permeable kainate receptors +1 more
		GSTM5	Unknown	15059925	CTD	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 +10 more
		GUCY1A1	Unknown	15059925	CTD	Purine metabolism Metabolic pathways cGMP-PKG signaling pathway +8 more
COLONIC POLYPS	MESH:D003111	ALOX5	Unknown	18927292	CTD	Arachidonic acid metabolism Metabolic pathways Efferocytosis +19 more

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Colonic neoplasms

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