Subtype of: Breast cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
breast carcinoma by gene expression profile	MONDO_0006116	EPHA7	Unknown	30537512	Open Targets	Axon guidance EPH-Ephrin signaling EPHA-mediated growth cone collapse +1 more
		ERBB2	Unknown	27406316 28270497 30914635 24185512 26960396 30531871 29807833 26563128 27502118 30181556 30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +48 more
		ERBB3	Unknown	28270497 24185512 29807833 26563128 27502118 30181556 30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway ErbB signaling pathway +19 more
		ERBB4	Unknown	30375428 30537512 27502118 30181556 28270497	Open Targets	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway +22 more
		ERCC2	Unknown	26960396 30537512	Open Targets	Basal transcription factors Nucleotide excision repair Formation of RNA Pol II elongation complex +19 more
		ERCC3	Unknown	30537512	Open Targets	Basal transcription factors Nucleotide excision repair Formation of RNA Pol II elongation complex +19 more
		ERCC4	Unknown	30205045	Open Targets	Nucleotide excision repair Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +4 more
		ERCC5	Unknown	30531871	Open Targets	Nucleotide excision repair Formation of Incision Complex in GG-NER Dual Incision in GG-NER +1 more
		ERG	Unknown	30205045 30062102	Open Targets	Transcriptional misregulation in cancer Prostate cancer
		ESR1	Unknown	24398047 26648736 25979954 30181556 26500237 26434753 29166868 30914635 24185512 28580595 28283903 37261814 27551012 29807833 28270497 37226020 26563128 27502118 24185510 30537512	Open Targets	Endocrine resistance Hormone signaling Estrogen signaling pathway +21 more
		ETV5	Unknown	30531871	Open Targets	Transcriptional misregulation in cancer Prostate cancer
		ETV6	Unknown	30537512	Open Targets	Transcriptional misregulation in cancer Signaling by membrane-tethered fusions of PDGFRA or PDGFRB
		EZH2	Unknown	25850943 30537512	Open Targets	Lysine degradation Metabolic pathways Polycomb repressive complex +7 more
		FANCA	Unknown	30537512	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FANCD2	Unknown	30062102 24185510	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
		FAS	Unknown	25850943	Open Targets	Platinum drug resistance MAPK signaling pathway Cytokine-cytokine receptor interaction +36 more
		FAT1	Unknown	30205045 32723837 30537512	Open Targets	—
		FAT3	Unknown	30062102 24185510	Open Targets	—
		FAT4	Unknown	27406316 24185510 30531871	Open Targets	Hippo signaling pathway - multiple species
		FBXO11	Unknown	24185512 30537512	Open Targets	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		FBXW7	Unknown	26563128 30537512 30181556 25850943	Open Targets	Ubiquitin mediated proteolysis Constitutive Signaling by NOTCH1 PEST Domain Mutants Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling +3 more
		FGFR1	Unknown	30914635 24185512 30537512	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +32 more
		FGFR2	Unknown	30531871 30914635 24185512 25850943 30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +26 more
		FGFR3	Unknown	30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +27 more
		FGFR4	Unknown	30205045 30537512	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +20 more
		FH	Unknown	30537512	Open Targets	Citrate cycle (TCA cycle) Pyruvate metabolism Metabolic pathways +5 more
		FIP1L1	Unknown	30537512	Open Targets	mRNA surveillance pathway Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway +4 more
		FLCN	Unknown	30205045 30537512	Open Targets	mTOR signaling pathway Renal cell carcinoma Amino acids regulate mTORC1
		FLNA	Unknown	27406316 24185510	Open Targets	MAPK signaling pathway Focal adhesion Salmonella infection +6 more
		FLT3	Unknown	30537512 24185512 25850943	Open Targets	MAPK signaling pathway Ras signaling pathway PI3K-Akt signaling pathway +8 more
		FLT4	Unknown	30537512 24185510 29807833	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +6 more
		FOXA1	Unknown	27406316 30205045 25850943 29807833 28270497 26563128 27502118 30181556 30537512	Open Targets	Estrogen-dependent gene expression
		FOXL2	Unknown	24185512	Open Targets	SUMOylation of transcription factors
		FOXO1	Unknown	30537512	Open Targets	FoxO signaling pathway AMPK signaling pathway Longevity regulating pathway +23 more
		FOXO3	Unknown	27406316	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway FoxO signaling pathway +26 more
		FOXP1	Unknown	30537512 30531871	Open Targets	MicroRNAs in cancer Transcriptional regulation of pluripotent stem cells
		FUBP1	Unknown	30537512	Open Targets	—
		GATA1	Unknown	30537512 25850943	Open Targets	RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 regulates transcription of genes involved in differentiation of HSCs Factors involved in megakaryocyte development and platelet production
		GATA2	Unknown	30375428	Open Targets	RUNX1 regulates transcription of genes involved in differentiation of HSCs Factors involved in megakaryocyte development and platelet production
		GATA3	Unknown	28270497 30062102 30914635 30205045 24185512 28580595 25850943 27566247 30531871 26960396 32723837 26563128 27135926 27502118 30181556 30537512	Open Targets	Th1 and Th2 cell differentiation Th17 cell differentiation Parathyroid hormone synthesis, secretion and action +6 more
		GLI1	Unknown	30205045 30537512	Open Targets	cAMP signaling pathway Hedgehog signaling pathway Pathways in cancer +5 more
		GNA11	Unknown	30537512	Open Targets	Calcium signaling pathway cGMP-PKG signaling pathway Hormone signaling +23 more
		GNAQ	Unknown	26527317	Open Targets	Rap1 signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway +52 more
		GNAS	Unknown	30914635 30537512	Open Targets	Endocrine resistance Rap1 signaling pathway Calcium signaling pathway +58 more
		GRIN2A	Unknown	30205045 24185512 30062102 30537512	Open Targets	Ras signaling pathway Rap1 signaling pathway Calcium signaling pathway +19 more
		GSK3B	Unknown	30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance ErbB signaling pathway Chemokine signaling pathway +59 more
		H3-3A	Unknown	25850943	Open Targets	Neutrophil extracellular trap formation Alcoholism Shigellosis +18 more
		H3C2	Unknown	30205045 30537512	Open Targets	Neutrophil extracellular trap formation Alcoholism Shigellosis +27 more
		HGF	Unknown	30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +29 more
		HIP1	Unknown	30531871	Open Targets	Huntington disease Pathways of neurodegeneration - multiple diseases Clathrin-mediated endocytosis

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Breast carcinoma by gene expression profile

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