Subtype of: Breast cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
breast carcinoma by gene expression profile	MONDO_0006116	MDM4	Unknown	30537512	Open Targets	p53 signaling pathway MicroRNAs in cancer Oxidative Stress Induced Senescence +6 more
		MED12	Unknown	30062102 25850943 28270497 26563128 27502118 30181556 30537512	Open Targets	Thyroid hormone signaling pathway PPARA activates gene expression Generic Transcription Pathway +1 more
		MEN1	Unknown	30205045 30537512	Open Targets	Cushing syndrome Transcriptional misregulation in cancer Formation of the beta-catenin:TCF transactivating complex +5 more
		MET	Unknown	30181556 30914635 26527317 24185512 28270497 30375428 30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +37 more
		MITF	Unknown	30537512 30531871	Open Targets	Mitophagy - animal Osteoclast differentiation Melanogenesis +4 more
		MLH1	Unknown	30537512 26527317 30062102 25850943	Open Targets	Platinum drug resistance Mismatch repair Fanconi anemia pathway +8 more
		MNX1	Unknown	30531871	Open Targets	Maturity onset diabetes of the young
		MPL	Unknown	30205045 24185512 25850943 30537512	Open Targets	Cytokine-cytokine receptor interaction Hormone signaling JAK-STAT signaling pathway
		MSH6	Unknown	24185512 30537512	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +4 more
		MTOR	Unknown	28270497 30181556 29807833 26563128 27502118 24185510 30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +61 more
		MUC16	Unknown	27406316 24185510 30531871	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUC4	Unknown	24185510 30531871	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MYB	Unknown	25850943 27502118 28270497	Open Targets	PI3K-Akt signaling pathway RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression
		MYC	Unknown	30914635 30537512	Open Targets	MAPK signaling pathway ErbB signaling pathway Cell cycle +45 more
		MYCN	Unknown	25850943 30537512	Open Targets	Transcriptional misregulation in cancer
		MYD88	Unknown	30537512	Open Targets	MAPK signaling pathway NF-kappa B signaling pathway Toll-like receptor signaling pathway +39 more
		MYH9	Unknown	27406316 30531871	Open Targets	Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction +8 more
		NBEA	Unknown	30531871	Open Targets	—
		NBN	Unknown	30537512	Open Targets	Homologous recombination Cellular senescence DNA Damage/Telomere Stress Induced Senescence +13 more
		NCOA1	Unknown	24185510	Open Targets	Estrogen signaling pathway Thyroid hormone signaling pathway Pathways in cancer +18 more
		NCOA2	Unknown	24185512	Open Targets	Estrogen signaling pathway Thyroid hormone signaling pathway RORA activates gene expression +14 more
		NCOR1	Unknown	30062102 30205045 27195705 28270497 26563128 27135926 27502118 30181556 30537512	Open Targets	Endocrine resistance TGF-beta signaling pathway Thyroid hormone signaling pathway +16 more
		NCOR2	Unknown	26563128 31854063 27502118 30181556 28270497	Open Targets	Notch signaling pathway Epstein-Barr virus infection PPARA activates gene expression +11 more
		NF1	Unknown	28270497 31854063 30914635 30205045 24185512 30531871 24185510 29807833 27502118 30181556 30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +2 more
		NFE2L2	Unknown	30537512 25850943	Open Targets	Protein processing in endoplasmic reticulum Parkinson disease Pathways in cancer +4 more
		NFKBIE	Unknown	30531871	Open Targets	Th1 and Th2 cell differentiation Th17 cell differentiation T cell receptor signaling pathway +6 more
		NKX2-1	Unknown	30205045 30062102 30537512	Open Targets	—
		NOTCH1	Unknown	22101766 30537512 29807833 25850943	Open Targets	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +20 more
		NOTCH2	Unknown	30205045 30537512 30062102 25850943	Open Targets	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +13 more
		NPM1	Unknown	30537512	Open Targets	Nuclear import of Rev protein SUMOylation of transcription cofactors Deposition of new CENPA-containing nucleosomes at the centromere +2 more
		NRAS	Unknown	30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +130 more
		NSD1	Unknown	30531871 30062102 30537512	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		NTRK1	Unknown	30531871 30537512 27502118 28270497	Open Targets	MAPK signaling pathway Ras signaling pathway Calcium signaling pathway +13 more
		NTRK2	Unknown	30537512	Open Targets	MAPK signaling pathway Ras signaling pathway Calcium signaling pathway +6 more
		NTRK3	Unknown	30537512 25850943	Open Targets	Calcium signaling pathway Neurotrophin signaling pathway Central carbon metabolism in cancer +4 more
		NUTM2D	Unknown	24185510	Open Targets	—
		P2RY8	Unknown	27406316	Open Targets	Neuroactive ligand-receptor interaction
		PABPC1	Unknown	27406316	Open Targets	mRNA surveillance pathway RNA degradation L13a-mediated translational silencing of Ceruloplasmin expression +5 more
		PALB2	Unknown	30062102 30537512	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Homologous Recombination (HRR) +3 more
		PATZ1	Unknown	24185510	Open Targets	—
		PAX5	Unknown	30537512	Open Targets	Transcriptional misregulation in cancer RUNX1 regulates transcription of genes involved in BCR signaling
		PBRM1	Unknown	24185512 30062102 30537512	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		PCM1	Unknown	27406316	Open Targets	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes +4 more
		PDE4DIP	Unknown	24185510	Open Targets	—
		PDGFRA	Unknown	30914635 26527317 30531871 29807833 26563128 30181556 30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +30 more
		PDGFRB	Unknown	30537512 31854063 25850943	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +22 more
		PIK3CA	Unknown	27406316 25979954 24185512 26527317 25243101 32723837 28270497 25850943 27135926 30062102 21512767 30914635 22213219 26960396 29807833 23982433 26563128 28446508 30181556 24185510 30205045 24663045 30531871 27126994 27502118 30537512	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +149 more
		PIK3CB	Unknown	30205045 27547031 30537512	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +126 more
		PIK3R1	Unknown	27502118 30537512 25850943 30181556 28270497	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +150 more
		PIK3R2	Unknown	30062102 30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +129 more

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Breast carcinoma by gene expression profile

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