Subtype of: Breast cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
breast carcinoma by gene expression profile	MONDO_0006116	ABL1	Unknown	30205045 24185512 30062102 29807833 25850943	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		ACVR2A	Unknown	25850943	Open Targets	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +3 more
		AFDN	Unknown	24185510	Open Targets	Ras signaling pathway Rap1 signaling pathway cAMP signaling pathway +4 more
		AFF4	Unknown	27406316 24185510	Open Targets	Viral life cycle - HIV-1 Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events +1 more
		AKAP9	Unknown	27406316 24185510 30531871	Open Targets	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes +7 more
		AKT1	Unknown	30205045 24663045 25850943 28270497 26563128 27502118 30181556 30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +131 more
		AKT2	Unknown	30537512 30062102 28270497	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +122 more
		AKT3	Unknown	30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +119 more
		ALK	Unknown	24185512 24185510 30537512	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		AMER1	Unknown	24185512 24185510 30537512	Open Targets	Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade Disassembly of the destruction complex and recruitment of AXIN to the membrane +8 more
		APC	Unknown	27406316 30205045 26527317 24185512 30375428 24185510 30537512	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		AR	Unknown	24185510 30537512	Open Targets	Oocyte meiosis Pathways in cancer Chemical carcinogenesis - receptor activation +7 more
		ARAF	Unknown	30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +41 more
		ARHGAP5	Unknown	30375428	Open Targets	Focal adhesion Leukocyte transendothelial migration Rho GTPase cycle
		ARHGEF10	Unknown	27406316	Open Targets	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
		ARID1A	Unknown	22101766 30062102 30914635 30205045 24185512 25850943 30531871 28270497 26563128 27502118 30181556 30537512	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID1B	Unknown	30181556 25850943 28270497 27502118 24185510 30537512	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID2	Unknown	30531871 30205045 25850943 24185510 30537512	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		ASPM	Unknown	24185510	Open Targets	—
		ASXL1	Unknown	30537512 24185512 25850943	Open Targets	Polycomb repressive complex UCH proteinases
		ASXL2	Unknown	30531871 24185510 30537512	Open Targets	Polycomb repressive complex UCH proteinases
		ATF1	Unknown	30531871	Open Targets	Aldosterone synthesis and secretion Transcriptional misregulation in cancer CREB phosphorylation +1 more
		ATM	Unknown	30205045 28580595 24185512 25850943 28270497 26563128 27502118 30181556 30537512	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		ATR	Unknown	28270497 27406316 30205045 29807833 30531871 27502118 30181556 30537512	Open Targets	Fanconi anemia pathway Cell cycle p53 signaling pathway +13 more
		ATRX	Unknown	30205045 24185512 30062102 30537512	Open Targets	Cell cycle
		AXIN1	Unknown	30537512	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		AXIN2	Unknown	30537512	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +15 more
		BAP1	Unknown	30537512	Open Targets	Polycomb repressive complex UCH proteinases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
		BARD1	Unknown	30537512	Open Targets	Homologous recombination HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) +11 more
		BAZ1A	Unknown	24185510	Open Targets	ATP-dependent chromatin remodeling
		BCL11A	Unknown	25850943	Open Targets	—
		BCL11B	Unknown	30062102	Open Targets	Transcriptional misregulation in cancer
		BCL2	Unknown	25850943	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +46 more
		BCL3	Unknown	30062102	Open Targets	C-type lectin receptor signaling pathway TNF signaling pathway
		BCL6	Unknown	25850943 30537512	Open Targets	FoxO signaling pathway Transcriptional misregulation in cancer Chemical carcinogenesis - receptor activation +3 more
		BCL9L	Unknown	32723837	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCOR	Unknown	30537512	Open Targets	Polycomb repressive complex
		BIRC3	Unknown	30537512	Open Targets	Platinum drug resistance NF-kappa B signaling pathway Ubiquitin mediated proteolysis +23 more
		BIRC6	Unknown	27502118 30375428 28270497	Open Targets	Ubiquitin mediated proteolysis Autophagy - animal Apoptosis - multiple species
		BLM	Unknown	25850943 30537512	Open Targets	Homologous recombination Fanconi anemia pathway Processive synthesis on the C-strand of the telomere +10 more
		BRAF	Unknown	28270497 30062102 25850943 26960396 29807833 30181556 30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA1	Unknown	24185512 24185510 28270497 27502118 30181556 30537512	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		BRCA2	Unknown	30914635 24185512 28270497 26563128 27502118 30181556 30537512	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BRD4	Unknown	30537512	Open Targets	—
		BRIP1	Unknown	27406316 30375428 24185510 30537512	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +8 more
		BTK	Unknown	30537512	Open Targets	NF-kappa B signaling pathway Osteoclast differentiation Platelet activation +17 more
		CARD11	Unknown	30537512 25850943	Open Targets	NF-kappa B signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway +4 more
		CASP8	Unknown	30537512 25850943 30181556 28270497	Open Targets	Platinum drug resistance p53 signaling pathway Apoptosis +53 more
		CBFB	Unknown	27406316 30531871 27135926 30537512 28270497	Open Targets	RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) Transcriptional regulation by RUNX2 RUNX1 regulates estrogen receptor mediated transcription +20 more
		CBL	Unknown	24185512 30537512	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +22 more

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Breast carcinoma by gene expression profile

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