Subtype of: Breast cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
breast carcinoma by gene expression profile	MONDO_0006116	CCNC	Unknown	30531871	Open Targets	PPARA activates gene expression Generic Transcription Pathway SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription +3 more
		CCND2	Unknown	30537512 25850943	Open Targets	FoxO signaling pathway Cell cycle p53 signaling pathway +18 more
		CCNE1	Unknown	30537512	Open Targets	Cell cycle Oocyte meiosis p53 signaling pathway +24 more
		CCR4	Unknown	27406316	Open Targets	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +4 more
		CD209	Unknown	30531871	Open Targets	Virion - Human immunodeficiency virus Virion - Flavivirus and Alphavirus Virion - Ebolavirus, Lyssavirus and Morbillivirus +7 more
		CD274	Unknown	30537512	Open Targets	Cell adhesion molecules PD-L1 expression and PD-1 checkpoint pathway in cancer PD-1 signaling
		CD79B	Unknown	25850943	Open Targets	B cell receptor signaling pathway CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
		CDC73	Unknown	24185512	Open Targets	Formation of RNA Pol II elongation complex Formation of the beta-catenin:TCF transactivating complex Hedgehog 'on' state +3 more
		CDH1	Unknown	27406316 31854063 21512767 30205045 24185512 28580595 30914635 25850943 30531871 28270497 26563128 27135926 27502118 30181556 30537512	Open Targets	Rap1 signaling pathway Apelin signaling pathway Hippo signaling pathway +15 more
		CDH10	Unknown	30375428 30531871	Open Targets	Adherens junctions interactions
		CDH17	Unknown	32723837	Open Targets	Gastric cancer Adherens junctions interactions
		CDK12	Unknown	30375428 30062102 30537512	Open Targets	TP53 Regulates Transcription of DNA Repair Genes
		CDKN1A	Unknown	30537512	Open Targets	Endocrine resistance Platinum drug resistance ErbB signaling pathway +56 more
		CDKN1B	Unknown	28270497 30062102 27502118 30181556 30537512	Open Targets	Endocrine resistance ErbB signaling pathway HIF-1 signaling pathway +28 more
		CDKN2A	Unknown	24185512 30537512	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CEBPA	Unknown	30537512 24185512 25850943	Open Targets	Non-alcoholic fatty liver disease Pathways in cancer Transcriptional misregulation in cancer +3 more
		CHD4	Unknown	30531871 30062102 32723837	Open Targets	ATP-dependent chromatin remodeling Human papillomavirus infection Viral carcinogenesis +5 more
		CHEK2	Unknown	28580595 30062102 30537512	Open Targets	Cell cycle p53 signaling pathway Cellular senescence +9 more
		CIC	Unknown	30062102 30537512	Open Targets	Spinocerebellar ataxia
		CLTC	Unknown	27406316 24185510	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +18 more
		COL3A1	Unknown	32723837	Open Targets	Platelet activation Cytoskeleton in muscle cells Relaxin signaling pathway +16 more
		CPEB3	Unknown	27406316	Open Targets	Oocyte meiosis Progesterone-mediated oocyte maturation
		CREBBP	Unknown	27406316 30537512 24185512 25850943 30531871	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		CSF1R	Unknown	30531871 30537512 27502118 30181556 28270497	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +10 more
		CSF3R	Unknown	30537512	Open Targets	Cytokine-cytokine receptor interaction PI3K-Akt signaling pathway JAK-STAT signaling pathway +3 more
		CSMD3	Unknown	27406316	Open Targets	—
		CTCF	Unknown	30205045 25850943 30531871 28270497 27502118 30181556 30537512	Open Targets	—
		CTNNB1	Unknown	30537512 30531871	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		CUL3	Unknown	30537512	Open Targets	Ubiquitin mediated proteolysis Hedgehog signaling pathway Degradation of DVL +4 more
		CUX1	Unknown	30062102 24185510 32723837	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Intra-Golgi traffic
		CYP2C8	Unknown	30375428	Open Targets	Arachidonic acid metabolism Linoleic acid metabolism Retinol metabolism +10 more
		DAXX	Unknown	24185512 30537512	Open Targets	MAPK signaling pathway Apoptosis Parkinson disease +6 more
		DCC	Unknown	30375428 30531871	Open Targets	Axon guidance Pathways in cancer Colorectal cancer +3 more
		DDR2	Unknown	30537512 29807833 28270497	Open Targets	Non-integrin membrane-ECM interactions
		DEK	Unknown	24185510	Open Targets	B-WICH complex positively regulates rRNA expression Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors Transcriptional regulation of granulopoiesis
		DICER1	Unknown	30537512 24185512 25850943	Open Targets	MicroRNAs in cancer MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
		DNAJB1	Unknown	30205045	Open Targets	Protein processing in endoplasmic reticulum Influenza A Regulation of HSF1-mediated heat shock response +4 more
		DNMT3A	Unknown	30205045 30537512 24185510 25850943	Open Targets	Cysteine and methionine metabolism Metabolic pathways Efferocytosis +3 more
		DROSHA	Unknown	30531871	Open Targets	Ribosome biogenesis in eukaryotes Proteoglycans in cancer MicroRNA (miRNA) biogenesis
		EBF1	Unknown	30531871	Open Targets	—
		ECT2L	Unknown	27406316	Open Targets	—
		EED	Unknown	30537512	Open Targets	Polycomb repressive complex PRC2 methylates histones and DNA Oxidative Stress Induced Senescence +4 more
		EGFR	Unknown	30537512 24185512 30531871	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Virion - Hepatitis viruses +79 more
		EIF1AX	Unknown	30537512	Open Targets	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits +3 more
		EIF4A2	Unknown	30537512	Open Targets	ISG15 antiviral mechanism L13a-mediated translational silencing of Ceruloplasmin expression Deadenylation of mRNA +4 more
		ELK4	Unknown	24185510	Open Targets	MAPK signaling pathway Human T-cell leukemia virus 1 infection Transcriptional misregulation in cancer
		ELL	Unknown	24185510	Open Targets	Viral life cycle - HIV-1 Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events +4 more
		EP300	Unknown	30537512 24185512 25850943	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +66 more
		EPAS1	Unknown	30537512	Open Targets	HIF-1 signaling pathway Pathways in cancer Renal cell carcinoma +6 more
		EPHA3	Unknown	27406316 30537512	Open Targets	Axon guidance EPH-Ephrin signaling EPHA-mediated growth cone collapse +1 more

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Breast carcinoma by gene expression profile

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