Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
BREAST CANCER	MONDO_0007254 MONDO:0007254	MYL3	Unknown	29059683 37340002	GWAS catalog	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Apelin signaling pathway +5 more
		MYO9B	Unknown	29059683	GWAS catalog	Motor proteins Rho GTPase cycle Regulation of actin dynamics for phagocytic cup formation +2 more
		MYT1	Unknown	29059683	GWAS catalog	—
		NAA25	Unknown	34018994	GWAS catalog	—
		NAALADL2	Unknown	38538606	GWAS catalog	—
		NALF1	Unknown	29059683	GWAS catalog	—
		NANOS3	Unknown	29059683 32139696	GWAS catalog	—
		NAPEPLD	Unknown	29059683	GWAS catalog	Retrograde endocannabinoid signaling Biosynthesis of A2E, implicated in retinal degradation
		NBPF10	Unknown	29059683	GWAS catalog	—
		NCOA1	Unknown	29058716 29059683	GWAS catalog	Estrogen signaling pathway Thyroid hormone signaling pathway Pathways in cancer +18 more
		NDFIP1	Unknown	29059683	GWAS catalog	—
		NEBL	Unknown	29059683	GWAS catalog	Cytoskeleton in muscle cells
		NEK10	Unknown	19330027 24493630 29059683 32808324 32887889 34290314 34594039 37340002 38538606 39789286	GWAS catalog	—
		NELFA	Unknown	29059683	GWAS catalog	Viral life cycle - HIV-1 Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex +4 more
		NF2	Unknown	29059683	GWAS catalog	Hippo signaling pathway Hippo signaling pathway - multiple species Tight junction +2 more
		NFIX	Unknown	29059683	GWAS catalog	—
		NIPAL1	Unknown	29059683 37340002	GWAS catalog	Miscellaneous transport and binding events
		NIPSNAP1	Unknown	29059683	GWAS catalog	—
		NKD1	Unknown	29059683	GWAS catalog	Wnt signaling pathway Hippo signaling pathway
		NKX2-6	Unknown	29059683	GWAS catalog	—
		NNT	Unknown	29059683	GWAS catalog	Nicotinate and nicotinamide metabolism Metabolic pathways Citric acid cycle (TCA cycle)
		NOL4L	Unknown	37380357	GWAS catalog	—
		NOL7	Unknown	37380357	GWAS catalog	—
		NOTCH2	Unknown	29059683 32424353	GWAS catalog	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +13 more
		NPTXR	Unknown	29059683	GWAS catalog	—
		NR3C1	Unknown	29059683	GWAS catalog	Neuroactive ligand-receptor interaction HSP90 chaperone cycle for steroid hormone receptors (SHR) Nuclear Receptor transcription pathway +2 more
		NRAP	Unknown	29059683	GWAS catalog	Cytoskeleton in muscle cells
		NREP	Unknown	29059683 32139696	GWAS catalog	—
		NRG3	Unknown	29059683	GWAS catalog	ErbB signaling pathway Amyotrophic lateral sclerosis Signaling by ERBB2 +15 more
		NRIP1	Unknown	29059683 32887889 36819030	GWAS catalog	SUMOylation of transcription cofactors Estrogen-dependent gene expression NR1H2 & NR1H3 regulate gene expression linked to lipogenesis +1 more
		NRSN1	Unknown	38538606	GWAS catalog	—
		NRXN3	Unknown	29059683 40229280	GWAS catalog	Cell adhesion molecules Neurexins and neuroligins
		NSF	Unknown	32887889 37380357	GWAS catalog	Synaptic vesicle cycle GABAergic synapse Vasopressin-regulated water reabsorption +6 more
		NTHL1	Unknown	—	GenCC	Base excision repair Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine +3 more
		NYAP2	Unknown	29059683 32139696	GWAS catalog	—
		OBP2B	Unknown	37636041	GWAS catalog	—
		OCIAD1	Unknown	37340002	GWAS catalog	—
		OMA1	Unknown	38538606	GWAS catalog	Spinocerebellar ataxia Regulation of Apoptosis
		OR2J1	Unknown	29059683	GWAS catalog	Olfactory transduction Olfactory Signaling Pathway
		OR2J3	Unknown	29059683	GWAS catalog	Olfactory transduction Olfactory Signaling Pathway
		OR5V1	Unknown	29059683	GWAS catalog	Olfactory transduction Olfactory Signaling Pathway
		OTUD7B	Unknown	25751625 29059683 32139696 37380357	GWAS catalog	TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway +1 more
		OVOL1	Unknown	23535729 25751625 29059683 32139696	GWAS catalog	—
		OXR1	Unknown	38501904	GWAS catalog	—
		P2RY1	Unknown	34290314	GWAS catalog	Rap1 signaling pathway Neuroactive ligand-receptor interaction Platelet activation +4 more
		P3H2	Unknown	29059683 38538606	GWAS catalog	Collagen biosynthesis and modifying enzymes
		P3R3URF-PIK3R3	Unknown	29059683 32139696 36819030	GWAS catalog	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +101 more
		PADI6	Unknown	29059683	GWAS catalog	Chromatin modifying enzymes
		PAG1	Unknown	29059683 38501904	GWAS catalog	GAB1 signalosome Phosphorylation of CD3 and TCR zeta chains
		PAIP1	Unknown	29059683	GWAS catalog	Deadenylation of mRNA
BREAST CARCINOMA	EFO_0000305	MYL3	Unknown	29059683 37340002	GWAS catalog	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Apelin signaling pathway +5 more
		MYO9B	Unknown	29059683 34290314	GWAS catalog	Motor proteins Rho GTPase cycle Regulation of actin dynamics for phagocytic cup formation +2 more
		MYT1	Unknown	29059683	GWAS catalog	—
		NAA25	Unknown	34018994	GWAS catalog	—
		NAALADL2	Unknown	38538606	GWAS catalog	—
		NALF1	Unknown	29059683	GWAS catalog	—
		NANOS3	Unknown	29059683 32139696	GWAS catalog	—
		NAPEPLD	Unknown	29059683	GWAS catalog	Retrograde endocannabinoid signaling Biosynthesis of A2E, implicated in retinal degradation
		NBPF10	Unknown	29059683	GWAS catalog	—
		NCOA1	Unknown	29058716 29059683	GWAS catalog	Estrogen signaling pathway Thyroid hormone signaling pathway Pathways in cancer +18 more
		NDFIP1	Unknown	29059683	GWAS catalog	—
		NEBL	Unknown	24785509 29059683	GWAS catalog	Cytoskeleton in muscle cells
		NEK10	Unknown	19330027 24493630 27197191 29059683 32808324 32887889 34290314 34594039 37340002 38538606 39789286	GWAS catalog	—
		NELFA	Unknown	29059683 32424353	GWAS catalog	Viral life cycle - HIV-1 Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex +4 more
		NF2	Unknown	29059683	GWAS catalog	Hippo signaling pathway Hippo signaling pathway - multiple species Tight junction +2 more
		NFIX	Unknown	29059683	GWAS catalog	—
		NIPAL1	Unknown	29059683 37340002	GWAS catalog	Miscellaneous transport and binding events
		NIPSNAP1	Unknown	29059683	GWAS catalog	—
		NKD1	Unknown	29059683	GWAS catalog	Wnt signaling pathway Hippo signaling pathway
		NKX2-6	Unknown	29059683	GWAS catalog	—
		NNT	Unknown	29059683	GWAS catalog	Nicotinate and nicotinamide metabolism Metabolic pathways Citric acid cycle (TCA cycle)
		NOTCH2	Unknown	29059683 32424353	GWAS catalog	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +13 more
		NPTXR	Unknown	29059683	GWAS catalog	—
		NR3C1	Unknown	29059683	GWAS catalog	Neuroactive ligand-receptor interaction HSP90 chaperone cycle for steroid hormone receptors (SHR) Nuclear Receptor transcription pathway +2 more
		NRAP	Unknown	29059683	GWAS catalog	Cytoskeleton in muscle cells
		NREP	Unknown	29059683 32139696	GWAS catalog	—
		NRG3	Unknown	29059683	GWAS catalog	ErbB signaling pathway Amyotrophic lateral sclerosis Signaling by ERBB2 +15 more
		NRIP1	Unknown	29059683 32887889	GWAS catalog	SUMOylation of transcription cofactors Estrogen-dependent gene expression NR1H2 & NR1H3 regulate gene expression linked to lipogenesis +1 more
		NRSN1	Unknown	38538606	GWAS catalog	—
		NRXN3	Unknown	29059683 40229280	GWAS catalog	Cell adhesion molecules Neurexins and neuroligins
		NSF	Unknown	32887889	GWAS catalog	Synaptic vesicle cycle GABAergic synapse Vasopressin-regulated water reabsorption +6 more
		NYAP2	Unknown	29059683 32139696	GWAS catalog	—
		OCIAD1	Unknown	37340002	GWAS catalog	—
		OMA1	Unknown	38538606	GWAS catalog	Spinocerebellar ataxia Regulation of Apoptosis
		OR2J1	Unknown	29059683	GWAS catalog	Olfactory transduction Olfactory Signaling Pathway
		OR2J3	Unknown	29059683	GWAS catalog	Olfactory transduction Olfactory Signaling Pathway
		OR5V1	Unknown	29059683	GWAS catalog	Olfactory transduction Olfactory Signaling Pathway
		OTUD7B	Unknown	25751625 29059683 32139696	GWAS catalog	TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway +1 more
		OVOL1	Unknown	23535729 25751625 29059683 32139696	GWAS catalog	—
		P2RY1	Unknown	34290314	GWAS catalog	Rap1 signaling pathway Neuroactive ligand-receptor interaction Platelet activation +4 more
		P3H2	Unknown	29059683 38538606	GWAS catalog	Collagen biosynthesis and modifying enzymes
		P3R3URF-PIK3R3	Unknown	29059683 32139696	GWAS catalog	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +101 more
		PADI6	Unknown	29059683 34290314	GWAS catalog	Chromatin modifying enzymes
		PAG1	Unknown	29059683	GWAS catalog	GAB1 signalosome Phosphorylation of CD3 and TCR zeta chains
		PAIP1	Unknown	29059683	GWAS catalog	Deadenylation of mRNA

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Breast cancer

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