DMTF1 (cyclin D binding myb like transcription factor 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 9988 |
| Gene name | Cyclin D binding myb like transcription factor 1 |
| Gene symbol | DMTF1 |
| Synonyms (NCBI Gene) |
DMP1DMTFMRULhDMP1
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| Chromosome | 7 |
| Chromosome location | 7q21.12 |
| Summary | This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathwa |
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miRNA
miRNA information provided by mirtarbase database.
458
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
11
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9Y222 | ||||||||||
| Protein name | Cyclin-D-binding Myb-like transcription factor 1 (hDMTF1) (Cyclin-D-interacting Myb-like protein 1) (hDMP1) | ||||||||||
| Protein function | Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest (By similarity). Binds to the consensus sequence 5'-CCCG[GT]ATGT-3' (By similarity). Isoform 1 ma | ||||||||||
| PDB | 2LLK | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed at relatively low levels in colonic mucosa, ovary, peripheral leukocytes, prostate and small intestine, and at higher levels in spleen, testis and thymus. Expressed in multiple regions of the brain and CNS including amygdala, | ||||||||||
| Sequence |
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| Sequence length | 760 | ||||||||||
| Interactions | View interactions | ||||||||||