NR1D2 (nuclear receptor subfamily 1 group D member 2)

Gene

• Entrez ID: 9975
• Gene name: Nuclear receptor subfamily 1 group D member 2
• Gene symbol: NR1D2
• Synonyms (NCBI Gene): BD73, EAR-1R, REVERBB, REVERBbeta, RVR
• Chromosome: 3
• Chromosome location: 3p24.2
• Summary: This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Al

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs1358487339	C>T	Likely-pathogenic	Non coding transcript variant, coding sequence variant, missense variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT021292	hsa-miR-125a-5p	Sequencing	20371350
MIRT021733	hsa-miR-132-3p	Microarray	17612493
MIRT025595	hsa-miR-10a-5p	Sequencing	20371350
MIRT037578	hsa-miR-744-5p	CLASH	23622248
MIRT120695	hsa-miR-216a-3p	PAR-CLIP	21572407
MIRT120701	hsa-miR-3681-3p	PAR-CLIP	21572407
MIRT120696	hsa-miR-27b-3p	PAR-CLIP	21572407
MIRT120694	hsa-miR-27a-3p	PAR-CLIP	21572407
MIRT120697	hsa-miR-128-3p	PAR-CLIP	21572407
MIRT547311	hsa-miR-412-3p	PAR-CLIP	21572407
MIRT547310	hsa-miR-6754-3p	PAR-CLIP	21572407
MIRT547309	hsa-miR-6837-3p	PAR-CLIP	21572407
MIRT547308	hsa-miR-3185	PAR-CLIP	21572407
MIRT120698	hsa-miR-513a-5p	PAR-CLIP	21572407
MIRT120700	hsa-miR-3611	PAR-CLIP	21572407
MIRT472010	hsa-miR-519a-3p	PAR-CLIP	23592263
MIRT472009	hsa-miR-519b-3p	PAR-CLIP	23592263
MIRT472008	hsa-miR-519c-3p	PAR-CLIP	23592263
MIRT472007	hsa-miR-302a-3p	PAR-CLIP	23592263
MIRT472006	hsa-miR-302b-3p	PAR-CLIP	23592263
MIRT472005	hsa-miR-302c-3p	PAR-CLIP	23592263
MIRT472004	hsa-miR-302d-3p	PAR-CLIP	23592263
MIRT472003	hsa-miR-302e	PAR-CLIP	23592263
MIRT472002	hsa-miR-372-3p	PAR-CLIP	23592263
MIRT472001	hsa-miR-373-3p	PAR-CLIP	23592263
MIRT472000	hsa-miR-520a-3p	PAR-CLIP	23592263
MIRT471999	hsa-miR-520b	PAR-CLIP	23592263
MIRT471998	hsa-miR-520c-3p	PAR-CLIP	23592263
MIRT471997	hsa-miR-520d-3p	PAR-CLIP	23592263
MIRT471996	hsa-miR-520e	PAR-CLIP	23592263
MIRT390101	hsa-miR-766-3p	PAR-CLIP	23592263
MIRT390102	hsa-miR-3925-3p	PAR-CLIP	23592263
MIRT209722	hsa-miR-509-3p	PAR-CLIP	23592263
MIRT471995	hsa-miR-1273c	PAR-CLIP	23592263
MIRT471994	hsa-miR-3683	PAR-CLIP	23592263
MIRT471993	hsa-miR-601	PAR-CLIP	23592263
MIRT390100	hsa-miR-145-5p	PAR-CLIP	23592263
MIRT390103	hsa-miR-5195-3p	PAR-CLIP	23592263
MIRT471992	hsa-miR-515-5p	PAR-CLIP	23592263
MIRT471991	hsa-miR-519e-5p	PAR-CLIP	23592263
MIRT471990	hsa-miR-6843-3p	PAR-CLIP	23592263
MIRT471989	hsa-miR-6848-3p	PAR-CLIP	23592263
MIRT735848	hsa-miR-195-3p	Microarray, qRT-PCR	31799078
MIRT735849	hsa-miR-340-3p	Microarray	31799078
MIRT120695	hsa-miR-216a-3p	PAR-CLIP	21572407
MIRT120701	hsa-miR-3681-3p	PAR-CLIP	21572407
MIRT120696	hsa-miR-27b-3p	PAR-CLIP	21572407
MIRT120694	hsa-miR-27a-3p	PAR-CLIP	21572407
MIRT120697	hsa-miR-128-3p	PAR-CLIP	21572407
MIRT547311	hsa-miR-412-3p	PAR-CLIP	21572407
MIRT547310	hsa-miR-6754-3p	PAR-CLIP	21572407
MIRT547309	hsa-miR-6837-3p	PAR-CLIP	21572407
MIRT547308	hsa-miR-3185	PAR-CLIP	21572407
MIRT120698	hsa-miR-513a-5p	PAR-CLIP	21572407
MIRT120700	hsa-miR-3611	PAR-CLIP	21572407
MIRT472010	hsa-miR-519a-3p	PAR-CLIP	23592263
MIRT472009	hsa-miR-519b-3p	PAR-CLIP	23592263
MIRT472008	hsa-miR-519c-3p	PAR-CLIP	23592263
MIRT472007	hsa-miR-302a-3p	PAR-CLIP	23592263
MIRT472006	hsa-miR-302b-3p	PAR-CLIP	23592263
MIRT472005	hsa-miR-302c-3p	PAR-CLIP	23592263
MIRT472004	hsa-miR-302d-3p	PAR-CLIP	23592263
MIRT472003	hsa-miR-302e	PAR-CLIP	23592263
MIRT472002	hsa-miR-372-3p	PAR-CLIP	23592263
MIRT472001	hsa-miR-373-3p	PAR-CLIP	23592263
MIRT472000	hsa-miR-520a-3p	PAR-CLIP	23592263
MIRT471999	hsa-miR-520b	PAR-CLIP	23592263
MIRT471998	hsa-miR-520c-3p	PAR-CLIP	23592263
MIRT471997	hsa-miR-520d-3p	PAR-CLIP	23592263
MIRT471996	hsa-miR-520e	PAR-CLIP	23592263
MIRT390101	hsa-miR-766-3p	PAR-CLIP	23592263
MIRT390102	hsa-miR-3925-3p	PAR-CLIP	23592263
MIRT209722	hsa-miR-509-3p	PAR-CLIP	23592263
MIRT471995	hsa-miR-1273c	PAR-CLIP	23592263
MIRT471994	hsa-miR-3683	PAR-CLIP	23592263
MIRT471993	hsa-miR-601	PAR-CLIP	23592263
MIRT390100	hsa-miR-145-5p	PAR-CLIP	23592263
MIRT390103	hsa-miR-5195-3p	PAR-CLIP	23592263
MIRT471992	hsa-miR-515-5p	PAR-CLIP	23592263
MIRT471991	hsa-miR-519e-5p	PAR-CLIP	23592263
MIRT471990	hsa-miR-6843-3p	PAR-CLIP	23592263
MIRT471989	hsa-miR-6848-3p	PAR-CLIP	23592263
MIRT1191996	hsa-miR-1207-5p	CLIP-seq
MIRT1191997	hsa-miR-142-5p	CLIP-seq
MIRT1191998	hsa-miR-145	CLIP-seq
MIRT1191999	hsa-miR-150	CLIP-seq
MIRT1192000	hsa-miR-183	CLIP-seq
MIRT1192001	hsa-miR-186	CLIP-seq
MIRT1192002	hsa-miR-194	CLIP-seq
MIRT1192003	hsa-miR-199a-3p	CLIP-seq
MIRT1192004	hsa-miR-199b-3p	CLIP-seq
MIRT1192005	hsa-miR-203	CLIP-seq
MIRT1192006	hsa-miR-2054	CLIP-seq
MIRT1192007	hsa-miR-25	CLIP-seq
MIRT1192008	hsa-miR-302a	CLIP-seq
MIRT1192009	hsa-miR-302b	CLIP-seq
MIRT1192010	hsa-miR-302c	CLIP-seq
MIRT1192011	hsa-miR-302d	CLIP-seq
MIRT1192012	hsa-miR-3074-5p	CLIP-seq
MIRT1192013	hsa-miR-3129-5p	CLIP-seq
MIRT1192014	hsa-miR-3140-5p	CLIP-seq
MIRT1192015	hsa-miR-3163	CLIP-seq
MIRT1192016	hsa-miR-32	CLIP-seq
MIRT1192017	hsa-miR-323-3p	CLIP-seq
MIRT1192018	hsa-miR-363	CLIP-seq
MIRT1192019	hsa-miR-365	CLIP-seq
MIRT1192020	hsa-miR-367	CLIP-seq
MIRT1192021	hsa-miR-372	CLIP-seq
MIRT1192022	hsa-miR-373	CLIP-seq
MIRT1192023	hsa-miR-3908	CLIP-seq
MIRT1192024	hsa-miR-3914	CLIP-seq
MIRT1192025	hsa-miR-4270	CLIP-seq
MIRT1192026	hsa-miR-4325	CLIP-seq
MIRT1192027	hsa-miR-4422	CLIP-seq
MIRT1192028	hsa-miR-4427	CLIP-seq
MIRT1192029	hsa-miR-4441	CLIP-seq
MIRT1192030	hsa-miR-450b-5p	CLIP-seq
MIRT1192031	hsa-miR-4633-5p	CLIP-seq
MIRT1192032	hsa-miR-4684-3p	CLIP-seq
MIRT1192033	hsa-miR-4708-5p	CLIP-seq
MIRT1192034	hsa-miR-4713-5p	CLIP-seq
MIRT1192035	hsa-miR-4736	CLIP-seq
MIRT1192036	hsa-miR-4756-3p	CLIP-seq
MIRT1192037	hsa-miR-4763-3p	CLIP-seq
MIRT1192038	hsa-miR-4789-3p	CLIP-seq
MIRT1192039	hsa-miR-4795-3p	CLIP-seq
MIRT1192040	hsa-miR-4797-5p	CLIP-seq
MIRT1192041	hsa-miR-486-5p	CLIP-seq
MIRT1192042	hsa-miR-511	CLIP-seq
MIRT1192043	hsa-miR-518a-5p	CLIP-seq
MIRT1192044	hsa-miR-519a	CLIP-seq
MIRT1192045	hsa-miR-527	CLIP-seq
MIRT1192046	hsa-miR-532-3p	CLIP-seq
MIRT1192047	hsa-miR-595	CLIP-seq
MIRT1192048	hsa-miR-628-5p	CLIP-seq
MIRT1192049	hsa-miR-656	CLIP-seq
MIRT1192050	hsa-miR-766	CLIP-seq
MIRT1192051	hsa-miR-873	CLIP-seq
MIRT1192052	hsa-miR-92a	CLIP-seq
MIRT1192053	hsa-miR-92b	CLIP-seq
MIRT1192054	hsa-miR-936	CLIP-seq
MIRT1192055	hsa-miR-938	CLIP-seq
MIRT1192056	hsa-miR-1245b-3p	CLIP-seq
MIRT1192057	hsa-miR-1256	CLIP-seq
MIRT1192058	hsa-miR-1271	CLIP-seq
MIRT1192059	hsa-miR-1294	CLIP-seq
MIRT1192060	hsa-miR-1297	CLIP-seq
MIRT1192061	hsa-miR-1305	CLIP-seq
MIRT1192062	hsa-miR-138	CLIP-seq
MIRT1192063	hsa-miR-140-3p	CLIP-seq
MIRT1191998	hsa-miR-145	CLIP-seq
MIRT1192064	hsa-miR-147b	CLIP-seq
MIRT1192065	hsa-miR-1587	CLIP-seq
MIRT1192066	hsa-miR-182	CLIP-seq
MIRT1192001	hsa-miR-186	CLIP-seq
MIRT1192005	hsa-miR-203	CLIP-seq
MIRT1192067	hsa-miR-210	CLIP-seq
MIRT1192068	hsa-miR-2110	CLIP-seq
MIRT1192069	hsa-miR-219-5p	CLIP-seq
MIRT1192007	hsa-miR-25	CLIP-seq
MIRT1192070	hsa-miR-26a	CLIP-seq
MIRT1192071	hsa-miR-26b	CLIP-seq
MIRT1192072	hsa-miR-28-3p	CLIP-seq
MIRT1192073	hsa-miR-299-5p	CLIP-seq
MIRT1192008	hsa-miR-302a	CLIP-seq
MIRT1192009	hsa-miR-302b	CLIP-seq
MIRT1192010	hsa-miR-302c	CLIP-seq
MIRT1192011	hsa-miR-302d	CLIP-seq
MIRT1192074	hsa-miR-3144-5p	CLIP-seq
MIRT1192075	hsa-miR-3148	CLIP-seq
MIRT1192076	hsa-miR-3150a-3p	CLIP-seq
MIRT1192077	hsa-miR-3151	CLIP-seq
MIRT1192078	hsa-miR-3161	CLIP-seq
MIRT1192015	hsa-miR-3163	CLIP-seq
MIRT1192079	hsa-miR-3168	CLIP-seq
MIRT1192080	hsa-miR-3180-5p	CLIP-seq
MIRT1192081	hsa-miR-3191	CLIP-seq
MIRT1192016	hsa-miR-32	CLIP-seq
MIRT1192017	hsa-miR-323-3p	CLIP-seq
MIRT1192082	hsa-miR-340	CLIP-seq
MIRT1192018	hsa-miR-363	CLIP-seq
MIRT1192019	hsa-miR-365	CLIP-seq
MIRT1192083	hsa-miR-3664-5p	CLIP-seq
MIRT1192020	hsa-miR-367	CLIP-seq
MIRT1192084	hsa-miR-3671	CLIP-seq
MIRT1192021	hsa-miR-372	CLIP-seq
MIRT1192022	hsa-miR-373	CLIP-seq
MIRT1192085	hsa-miR-376c	CLIP-seq
MIRT1192086	hsa-miR-377	CLIP-seq
MIRT1192087	hsa-miR-3929	CLIP-seq
MIRT1192088	hsa-miR-3941	CLIP-seq
MIRT1192089	hsa-miR-3978	CLIP-seq
MIRT1192090	hsa-miR-409-5p	CLIP-seq
MIRT1192091	hsa-miR-4263	CLIP-seq
MIRT1192025	hsa-miR-4270	CLIP-seq
MIRT1192092	hsa-miR-4316	CLIP-seq
MIRT1192026	hsa-miR-4325	CLIP-seq
MIRT1192093	hsa-miR-4419b	CLIP-seq
MIRT1192029	hsa-miR-4441	CLIP-seq
MIRT1192094	hsa-miR-4445	CLIP-seq
MIRT1192095	hsa-miR-4453	CLIP-seq
MIRT1192096	hsa-miR-4461	CLIP-seq
MIRT1192097	hsa-miR-4465	CLIP-seq
MIRT1192098	hsa-miR-4478	CLIP-seq
MIRT1192030	hsa-miR-450b-5p	CLIP-seq
MIRT1192099	hsa-miR-4538	CLIP-seq
MIRT1192100	hsa-miR-4643	CLIP-seq
MIRT1192101	hsa-miR-4652-5p	CLIP-seq
MIRT1192102	hsa-miR-466	CLIP-seq
MIRT1192103	hsa-miR-4672	CLIP-seq
MIRT1192104	hsa-miR-4674	CLIP-seq
MIRT1192105	hsa-miR-4677-3p	CLIP-seq
MIRT1192106	hsa-miR-4679	CLIP-seq
MIRT1192107	hsa-miR-4683	CLIP-seq
MIRT1192032	hsa-miR-4684-3p	CLIP-seq
MIRT1192108	hsa-miR-4698	CLIP-seq
MIRT1192109	hsa-miR-4699-3p	CLIP-seq
MIRT1192110	hsa-miR-4704-5p	CLIP-seq
MIRT1192111	hsa-miR-4716-5p	CLIP-seq
MIRT1192112	hsa-miR-4724-3p	CLIP-seq
MIRT1192113	hsa-miR-4744	CLIP-seq
MIRT1192036	hsa-miR-4756-3p	CLIP-seq
MIRT1192114	hsa-miR-4775	CLIP-seq
MIRT1192115	hsa-miR-4782-3p	CLIP-seq
MIRT1192038	hsa-miR-4789-3p	CLIP-seq
MIRT1192040	hsa-miR-4797-5p	CLIP-seq
MIRT1192116	hsa-miR-486-3p	CLIP-seq
MIRT1192117	hsa-miR-508-3p	CLIP-seq
MIRT1192043	hsa-miR-518a-5p	CLIP-seq
MIRT1192044	hsa-miR-519a	CLIP-seq
MIRT1192118	hsa-miR-520a-5p	CLIP-seq
MIRT1192119	hsa-miR-522	CLIP-seq
MIRT1192120	hsa-miR-525-5p	CLIP-seq
MIRT1192045	hsa-miR-527	CLIP-seq
MIRT1192121	hsa-miR-548u	CLIP-seq
MIRT1192122	hsa-miR-561	CLIP-seq
MIRT1192123	hsa-miR-576-5p	CLIP-seq
MIRT1192124	hsa-miR-579	CLIP-seq
MIRT1192125	hsa-miR-587	CLIP-seq
MIRT1192126	hsa-miR-590-3p	CLIP-seq
MIRT1192047	hsa-miR-595	CLIP-seq
MIRT1192127	hsa-miR-603	CLIP-seq
MIRT1192128	hsa-miR-607	CLIP-seq
MIRT1192129	hsa-miR-618	CLIP-seq
MIRT1192048	hsa-miR-628-5p	CLIP-seq
MIRT1192130	hsa-miR-659	CLIP-seq
MIRT1192050	hsa-miR-766	CLIP-seq
MIRT1192131	hsa-miR-802	CLIP-seq
MIRT1192052	hsa-miR-92a	CLIP-seq
MIRT1192053	hsa-miR-92b	CLIP-seq
MIRT1192055	hsa-miR-938	CLIP-seq
MIRT1192132	hsa-miR-96	CLIP-seq
MIRT2055639	hsa-miR-101	CLIP-seq
MIRT2055640	hsa-miR-103a	CLIP-seq
MIRT2055641	hsa-miR-107	CLIP-seq
MIRT2055642	hsa-miR-1184	CLIP-seq
MIRT2055643	hsa-miR-1224-3p	CLIP-seq
MIRT1192057	hsa-miR-1256	CLIP-seq
MIRT2055644	hsa-miR-1260	CLIP-seq
MIRT2055645	hsa-miR-1260b	CLIP-seq
MIRT2055646	hsa-miR-128	CLIP-seq
MIRT2055647	hsa-miR-1280	CLIP-seq
MIRT1192059	hsa-miR-1294	CLIP-seq
MIRT2055648	hsa-miR-129-5p	CLIP-seq
MIRT1192060	hsa-miR-1297	CLIP-seq
MIRT2055649	hsa-miR-132	CLIP-seq
MIRT1191997	hsa-miR-142-5p	CLIP-seq
MIRT2055650	hsa-miR-144	CLIP-seq
MIRT1191998	hsa-miR-145	CLIP-seq
MIRT2055651	hsa-miR-1912	CLIP-seq
MIRT1192002	hsa-miR-194	CLIP-seq
MIRT1192005	hsa-miR-203	CLIP-seq
MIRT1192068	hsa-miR-2110	CLIP-seq
MIRT2055652	hsa-miR-212	CLIP-seq
MIRT1192007	hsa-miR-25	CLIP-seq
MIRT2055653	hsa-miR-2681	CLIP-seq
MIRT1192070	hsa-miR-26a	CLIP-seq
MIRT1192071	hsa-miR-26b	CLIP-seq
MIRT2055654	hsa-miR-27a	CLIP-seq
MIRT2055655	hsa-miR-27b	CLIP-seq
MIRT1192008	hsa-miR-302a	CLIP-seq
MIRT1192009	hsa-miR-302b	CLIP-seq
MIRT1192010	hsa-miR-302c	CLIP-seq
MIRT1192011	hsa-miR-302d	CLIP-seq
MIRT1192012	hsa-miR-3074-5p	CLIP-seq
MIRT2055656	hsa-miR-3130-5p	CLIP-seq
MIRT2055657	hsa-miR-3143	CLIP-seq
MIRT1192074	hsa-miR-3144-5p	CLIP-seq
MIRT1192076	hsa-miR-3150a-3p	CLIP-seq
MIRT1192077	hsa-miR-3151	CLIP-seq
MIRT1192080	hsa-miR-3180-5p	CLIP-seq
MIRT1192081	hsa-miR-3191	CLIP-seq
MIRT1192016	hsa-miR-32	CLIP-seq
MIRT1192017	hsa-miR-323-3p	CLIP-seq
MIRT2055658	hsa-miR-3613-3p	CLIP-seq
MIRT2055659	hsa-miR-361-3p	CLIP-seq
MIRT1192018	hsa-miR-363	CLIP-seq
MIRT2055660	hsa-miR-3657	CLIP-seq
MIRT1192083	hsa-miR-3664-5p	CLIP-seq
MIRT1192020	hsa-miR-367	CLIP-seq
MIRT1192084	hsa-miR-3671	CLIP-seq
MIRT2055661	hsa-miR-3685	CLIP-seq
MIRT1192021	hsa-miR-372	CLIP-seq
MIRT1192022	hsa-miR-373	CLIP-seq
MIRT2055662	hsa-miR-384	CLIP-seq
MIRT1192023	hsa-miR-3908	CLIP-seq
MIRT2055663	hsa-miR-3936	CLIP-seq
MIRT1192088	hsa-miR-3941	CLIP-seq
MIRT2055664	hsa-miR-410	CLIP-seq
MIRT2055665	hsa-miR-412	CLIP-seq
MIRT2055666	hsa-miR-421	CLIP-seq
MIRT1192091	hsa-miR-4263	CLIP-seq
MIRT1192025	hsa-miR-4270	CLIP-seq
MIRT2055667	hsa-miR-4276	CLIP-seq
MIRT2055668	hsa-miR-4302	CLIP-seq
MIRT1192092	hsa-miR-4316	CLIP-seq
MIRT1192029	hsa-miR-4441	CLIP-seq
MIRT1192097	hsa-miR-4465	CLIP-seq
MIRT2055669	hsa-miR-4477a	CLIP-seq
MIRT2055670	hsa-miR-4482	CLIP-seq
MIRT1192030	hsa-miR-450b-5p	CLIP-seq
MIRT2055671	hsa-miR-4524	CLIP-seq
MIRT2055672	hsa-miR-4528	CLIP-seq
MIRT1192100	hsa-miR-4643	CLIP-seq
MIRT1192101	hsa-miR-4652-5p	CLIP-seq
MIRT2055673	hsa-miR-4666-5p	CLIP-seq
MIRT1192105	hsa-miR-4677-3p	CLIP-seq
MIRT1192106	hsa-miR-4679	CLIP-seq
MIRT2055674	hsa-miR-4688	CLIP-seq
MIRT1192109	hsa-miR-4699-3p	CLIP-seq
MIRT1192033	hsa-miR-4708-5p	CLIP-seq
MIRT2055675	hsa-miR-4709-3p	CLIP-seq
MIRT2055676	hsa-miR-4709-5p	CLIP-seq
MIRT1192036	hsa-miR-4756-3p	CLIP-seq
MIRT2055677	hsa-miR-4760-3p	CLIP-seq
MIRT2055678	hsa-miR-4789-5p	CLIP-seq
MIRT1192040	hsa-miR-4797-5p	CLIP-seq
MIRT2055679	hsa-miR-485-3p	CLIP-seq
MIRT1192116	hsa-miR-486-3p	CLIP-seq
MIRT1192041	hsa-miR-486-5p	CLIP-seq
MIRT2055680	hsa-miR-507	CLIP-seq
MIRT1192042	hsa-miR-511	CLIP-seq
MIRT2055681	hsa-miR-513c	CLIP-seq
MIRT2055682	hsa-miR-514b-5p	CLIP-seq
MIRT1192044	hsa-miR-519a	CLIP-seq
MIRT1192118	hsa-miR-520a-5p	CLIP-seq
MIRT1192120	hsa-miR-525-5p	CLIP-seq
MIRT2055683	hsa-miR-548ag	CLIP-seq
MIRT2055684	hsa-miR-548ai	CLIP-seq
MIRT2055685	hsa-miR-557	CLIP-seq
MIRT1192122	hsa-miR-561	CLIP-seq
MIRT2055686	hsa-miR-568	CLIP-seq
MIRT2055687	hsa-miR-584	CLIP-seq
MIRT2055688	hsa-miR-586	CLIP-seq
MIRT1192126	hsa-miR-590-3p	CLIP-seq
MIRT1192127	hsa-miR-603	CLIP-seq
MIRT2055689	hsa-miR-605	CLIP-seq
MIRT1192128	hsa-miR-607	CLIP-seq
MIRT1192129	hsa-miR-618	CLIP-seq
MIRT1192049	hsa-miR-656	CLIP-seq
MIRT2055690	hsa-miR-718	CLIP-seq
MIRT1192050	hsa-miR-766	CLIP-seq
MIRT1192131	hsa-miR-802	CLIP-seq
MIRT1192052	hsa-miR-92a	CLIP-seq
MIRT1192053	hsa-miR-92b	CLIP-seq
MIRT1191997	hsa-miR-142-5p	CLIP-seq
MIRT2055639	hsa-miR-101	CLIP-seq
MIRT2055640	hsa-miR-103a	CLIP-seq
MIRT2055641	hsa-miR-107	CLIP-seq
MIRT2055642	hsa-miR-1184	CLIP-seq
MIRT2055646	hsa-miR-128	CLIP-seq
MIRT1192059	hsa-miR-1294	CLIP-seq
MIRT1192060	hsa-miR-1297	CLIP-seq
MIRT2055649	hsa-miR-132	CLIP-seq
MIRT1192063	hsa-miR-140-3p	CLIP-seq
MIRT1191997	hsa-miR-142-5p	CLIP-seq
MIRT2055650	hsa-miR-144	CLIP-seq
MIRT1191998	hsa-miR-145	CLIP-seq
MIRT1191999	hsa-miR-150	CLIP-seq
MIRT2284523	hsa-miR-181a	CLIP-seq
MIRT2284524	hsa-miR-181b	CLIP-seq
MIRT2284525	hsa-miR-181c	CLIP-seq
MIRT2284526	hsa-miR-181d	CLIP-seq
MIRT2055651	hsa-miR-1912	CLIP-seq
MIRT1192002	hsa-miR-194	CLIP-seq
MIRT2055652	hsa-miR-212	CLIP-seq
MIRT2055653	hsa-miR-2681	CLIP-seq
MIRT1192070	hsa-miR-26a	CLIP-seq
MIRT1192071	hsa-miR-26b	CLIP-seq
MIRT2055654	hsa-miR-27a	CLIP-seq
MIRT2055655	hsa-miR-27b	CLIP-seq
MIRT1192008	hsa-miR-302a	CLIP-seq
MIRT1192009	hsa-miR-302b	CLIP-seq
MIRT1192010	hsa-miR-302c	CLIP-seq
MIRT1192011	hsa-miR-302d	CLIP-seq
MIRT2055656	hsa-miR-3130-5p	CLIP-seq
MIRT2055657	hsa-miR-3143	CLIP-seq
MIRT1192078	hsa-miR-3161	CLIP-seq
MIRT1192080	hsa-miR-3180-5p	CLIP-seq
MIRT1192017	hsa-miR-323-3p	CLIP-seq
MIRT2284527	hsa-miR-331-5p	CLIP-seq
MIRT2055659	hsa-miR-361-3p	CLIP-seq
MIRT1192083	hsa-miR-3664-5p	CLIP-seq
MIRT2055661	hsa-miR-3685	CLIP-seq
MIRT2284528	hsa-miR-371-3p	CLIP-seq
MIRT2284529	hsa-miR-371b-3p	CLIP-seq
MIRT1192021	hsa-miR-372	CLIP-seq
MIRT1192022	hsa-miR-373	CLIP-seq
MIRT1192085	hsa-miR-376c	CLIP-seq
MIRT2055662	hsa-miR-384	CLIP-seq
MIRT1192088	hsa-miR-3941	CLIP-seq
MIRT2284530	hsa-miR-3973	CLIP-seq
MIRT2055665	hsa-miR-412	CLIP-seq
MIRT2055666	hsa-miR-421	CLIP-seq
MIRT2284531	hsa-miR-4262	CLIP-seq
MIRT1192025	hsa-miR-4270	CLIP-seq
MIRT2284532	hsa-miR-4272	CLIP-seq
MIRT2284533	hsa-miR-4274	CLIP-seq
MIRT2055667	hsa-miR-4276	CLIP-seq
MIRT2284534	hsa-miR-4291	CLIP-seq
MIRT2055668	hsa-miR-4302	CLIP-seq
MIRT1192092	hsa-miR-4316	CLIP-seq
MIRT1192027	hsa-miR-4422	CLIP-seq
MIRT1192029	hsa-miR-4441	CLIP-seq
MIRT1192096	hsa-miR-4461	CLIP-seq
MIRT1192097	hsa-miR-4465	CLIP-seq
MIRT2055669	hsa-miR-4477a	CLIP-seq
MIRT2055670	hsa-miR-4482	CLIP-seq
MIRT2284535	hsa-miR-4519	CLIP-seq
MIRT2055671	hsa-miR-4524	CLIP-seq
MIRT1192100	hsa-miR-4643	CLIP-seq
MIRT2284536	hsa-miR-4668-3p	CLIP-seq
MIRT1192105	hsa-miR-4677-3p	CLIP-seq
MIRT2284537	hsa-miR-4678	CLIP-seq
MIRT1192106	hsa-miR-4679	CLIP-seq
MIRT1192107	hsa-miR-4683	CLIP-seq
MIRT1192108	hsa-miR-4698	CLIP-seq
MIRT1192109	hsa-miR-4699-3p	CLIP-seq
MIRT1192033	hsa-miR-4708-5p	CLIP-seq
MIRT2055675	hsa-miR-4709-3p	CLIP-seq
MIRT2055676	hsa-miR-4709-5p	CLIP-seq
MIRT1192034	hsa-miR-4713-5p	CLIP-seq
MIRT1192111	hsa-miR-4716-5p	CLIP-seq
MIRT2055677	hsa-miR-4760-3p	CLIP-seq
MIRT2284538	hsa-miR-4778-3p	CLIP-seq
MIRT2055679	hsa-miR-485-3p	CLIP-seq
MIRT1192116	hsa-miR-486-3p	CLIP-seq
MIRT2284539	hsa-miR-491-3p	CLIP-seq
MIRT2055681	hsa-miR-513c	CLIP-seq
MIRT2055682	hsa-miR-514b-5p	CLIP-seq
MIRT2284540	hsa-miR-515-3p	CLIP-seq
MIRT1192044	hsa-miR-519a	CLIP-seq
MIRT2284541	hsa-miR-519e	CLIP-seq
MIRT1192118	hsa-miR-520a-5p	CLIP-seq
MIRT2284542	hsa-miR-520g	CLIP-seq
MIRT2284543	hsa-miR-520h	CLIP-seq
MIRT1192120	hsa-miR-525-5p	CLIP-seq
MIRT1192046	hsa-miR-532-3p	CLIP-seq
MIRT2284544	hsa-miR-543	CLIP-seq
MIRT2284545	hsa-miR-545	CLIP-seq
MIRT2284546	hsa-miR-548an	CLIP-seq
MIRT1192122	hsa-miR-561	CLIP-seq
MIRT2284547	hsa-miR-578	CLIP-seq
MIRT1192124	hsa-miR-579	CLIP-seq
MIRT2284548	hsa-miR-582-5p	CLIP-seq
MIRT1192125	hsa-miR-587	CLIP-seq
MIRT1192127	hsa-miR-603	CLIP-seq
MIRT2055689	hsa-miR-605	CLIP-seq
MIRT1192129	hsa-miR-618	CLIP-seq
MIRT2284549	hsa-miR-643	CLIP-seq
MIRT2055690	hsa-miR-718	CLIP-seq
MIRT1192050	hsa-miR-766	CLIP-seq
MIRT1192131	hsa-miR-802	CLIP-seq
MIRT1192025	hsa-miR-4270	CLIP-seq
MIRT1192029	hsa-miR-4441	CLIP-seq
MIRT1192033	hsa-miR-4708-5p	CLIP-seq
MIRT1192019	hsa-miR-365	CLIP-seq
MIRT2439072	hsa-miR-3662	CLIP-seq
MIRT2439073	hsa-miR-4495	CLIP-seq
MIRT2284536	hsa-miR-4668-3p	CLIP-seq
MIRT2055639	hsa-miR-101	CLIP-seq
MIRT2055650	hsa-miR-144	CLIP-seq
MIRT2055639	hsa-miR-101	CLIP-seq
MIRT2582406	hsa-miR-1237	CLIP-seq
MIRT2582407	hsa-miR-1248	CLIP-seq
MIRT2582408	hsa-miR-1270	CLIP-seq
MIRT2055648	hsa-miR-129-5p	CLIP-seq
MIRT2055650	hsa-miR-144	CLIP-seq
MIRT1192002	hsa-miR-194	CLIP-seq
MIRT1192012	hsa-miR-3074-5p	CLIP-seq
MIRT1192017	hsa-miR-323-3p	CLIP-seq
MIRT2582409	hsa-miR-3607-3p	CLIP-seq
MIRT1192019	hsa-miR-365	CLIP-seq
MIRT2055660	hsa-miR-3657	CLIP-seq
MIRT2439072	hsa-miR-3662	CLIP-seq
MIRT1192084	hsa-miR-3671	CLIP-seq
MIRT2582410	hsa-miR-3679-3p	CLIP-seq
MIRT2582411	hsa-miR-3686	CLIP-seq
MIRT2284530	hsa-miR-3973	CLIP-seq
MIRT2055666	hsa-miR-421	CLIP-seq
MIRT1192027	hsa-miR-4422	CLIP-seq
MIRT2582412	hsa-miR-4438	CLIP-seq
MIRT2582413	hsa-miR-4446-5p	CLIP-seq
MIRT2055669	hsa-miR-4477a	CLIP-seq
MIRT2439073	hsa-miR-4495	CLIP-seq
MIRT1192030	hsa-miR-450b-5p	CLIP-seq
MIRT2284536	hsa-miR-4668-3p	CLIP-seq
MIRT2582414	hsa-miR-4675	CLIP-seq
MIRT1192107	hsa-miR-4683	CLIP-seq
MIRT2582415	hsa-miR-4687-3p	CLIP-seq
MIRT2055676	hsa-miR-4709-5p	CLIP-seq
MIRT2582416	hsa-miR-4733-5p	CLIP-seq
MIRT2582417	hsa-miR-4735-5p	CLIP-seq
MIRT2582418	hsa-miR-4741	CLIP-seq
MIRT2055677	hsa-miR-4760-3p	CLIP-seq
MIRT1192114	hsa-miR-4775	CLIP-seq
MIRT2582419	hsa-miR-4802-3p	CLIP-seq
MIRT2055679	hsa-miR-485-3p	CLIP-seq
MIRT1192041	hsa-miR-486-5p	CLIP-seq
MIRT2055680	hsa-miR-507	CLIP-seq
MIRT2582420	hsa-miR-513a-3p	CLIP-seq
MIRT2582421	hsa-miR-518a-3p	CLIP-seq
MIRT2582422	hsa-miR-518b	CLIP-seq
MIRT2582423	hsa-miR-518c	CLIP-seq
MIRT2582424	hsa-miR-518d-3p	CLIP-seq
MIRT2582425	hsa-miR-518f	CLIP-seq
MIRT2284542	hsa-miR-520g	CLIP-seq
MIRT2284543	hsa-miR-520h	CLIP-seq
MIRT2582426	hsa-miR-548a-5p	CLIP-seq
MIRT2582427	hsa-miR-548ab	CLIP-seq
MIRT2582428	hsa-miR-548ak	CLIP-seq
MIRT2582429	hsa-miR-548b-5p	CLIP-seq
MIRT2582430	hsa-miR-548c-5p	CLIP-seq
MIRT2582431	hsa-miR-548d-5p	CLIP-seq
MIRT2582432	hsa-miR-548h	CLIP-seq
MIRT2582433	hsa-miR-548i	CLIP-seq
MIRT2582434	hsa-miR-548j	CLIP-seq
MIRT2582435	hsa-miR-548w	CLIP-seq
MIRT2582436	hsa-miR-548y	CLIP-seq
MIRT2055685	hsa-miR-557	CLIP-seq
MIRT2582437	hsa-miR-559	CLIP-seq
MIRT1192123	hsa-miR-576-5p	CLIP-seq
MIRT1192126	hsa-miR-590-3p	CLIP-seq
MIRT2582438	hsa-miR-598	CLIP-seq
MIRT2055689	hsa-miR-605	CLIP-seq
MIRT2582439	hsa-miR-620	CLIP-seq
MIRT1192131	hsa-miR-802	CLIP-seq
MIRT2055639	hsa-miR-101	CLIP-seq
MIRT2582408	hsa-miR-1270	CLIP-seq
MIRT2055646	hsa-miR-128	CLIP-seq
MIRT1191997	hsa-miR-142-5p	CLIP-seq
MIRT2055650	hsa-miR-144	CLIP-seq
MIRT1192002	hsa-miR-194	CLIP-seq
MIRT2055654	hsa-miR-27a	CLIP-seq
MIRT2055655	hsa-miR-27b	CLIP-seq
MIRT1192012	hsa-miR-3074-5p	CLIP-seq
MIRT1192019	hsa-miR-365	CLIP-seq
MIRT2439072	hsa-miR-3662	CLIP-seq
MIRT1192084	hsa-miR-3671	CLIP-seq
MIRT2284530	hsa-miR-3973	CLIP-seq
MIRT2055665	hsa-miR-412	CLIP-seq
MIRT2686529	hsa-miR-4275	CLIP-seq
MIRT1192027	hsa-miR-4422	CLIP-seq
MIRT2582412	hsa-miR-4438	CLIP-seq
MIRT2439073	hsa-miR-4495	CLIP-seq
MIRT2686530	hsa-miR-4536	CLIP-seq
MIRT2284536	hsa-miR-4668-3p	CLIP-seq
MIRT1192107	hsa-miR-4683	CLIP-seq
MIRT2055677	hsa-miR-4760-3p	CLIP-seq
MIRT1192114	hsa-miR-4775	CLIP-seq
MIRT2582419	hsa-miR-4802-3p	CLIP-seq
MIRT2055679	hsa-miR-485-3p	CLIP-seq
MIRT1192041	hsa-miR-486-5p	CLIP-seq
MIRT2582421	hsa-miR-518a-3p	CLIP-seq
MIRT2582422	hsa-miR-518b	CLIP-seq
MIRT2582423	hsa-miR-518c	CLIP-seq
MIRT2582424	hsa-miR-518d-3p	CLIP-seq
MIRT2582425	hsa-miR-518f	CLIP-seq
MIRT2284542	hsa-miR-520g	CLIP-seq
MIRT2284543	hsa-miR-520h	CLIP-seq
MIRT2582426	hsa-miR-548a-5p	CLIP-seq
MIRT2582427	hsa-miR-548ab	CLIP-seq
MIRT2582428	hsa-miR-548ak	CLIP-seq
MIRT2582429	hsa-miR-548b-5p	CLIP-seq
MIRT2582430	hsa-miR-548c-5p	CLIP-seq
MIRT2582431	hsa-miR-548d-5p	CLIP-seq
MIRT2582432	hsa-miR-548h	CLIP-seq
MIRT2582433	hsa-miR-548i	CLIP-seq
MIRT2582434	hsa-miR-548j	CLIP-seq
MIRT2582435	hsa-miR-548w	CLIP-seq
MIRT2582436	hsa-miR-548y	CLIP-seq
MIRT2582437	hsa-miR-559	CLIP-seq
MIRT1192122	hsa-miR-561	CLIP-seq
MIRT2686531	hsa-miR-581	CLIP-seq
MIRT1192125	hsa-miR-587	CLIP-seq
MIRT1192126	hsa-miR-590-3p	CLIP-seq
MIRT2582438	hsa-miR-598	CLIP-seq
MIRT2055689	hsa-miR-605	CLIP-seq
MIRT2582439	hsa-miR-620	CLIP-seq
MIRT1192131	hsa-miR-802	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IBA
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	17892483, 17996965
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0000987	Function	Cis-regulatory region sequence-specific DNA binding	IEA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0004879	Function	Nuclear receptor activity	IBA
GO:0004879	Function	Nuclear receptor activity	TAS	7997240
GO:0005515	Function	Protein binding	IPI	17892483, 17996965, 23455924, 23555304, 26392558, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	17892483, 17996965
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	7997240
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	TAS	7997240
GO:0008270	Function	Zinc ion binding	IEA
GO:0009755	Process	Hormone-mediated signaling pathway	IBA
GO:0019216	Process	Regulation of lipid metabolic process	IEA
GO:0019216	Process	Regulation of lipid metabolic process	ISS
GO:0030154	Process	Cell differentiation	IBA
GO:0030522	Process	Intracellular receptor signaling pathway	IBA
GO:0042752	Process	Regulation of circadian rhythm	IEA
GO:0042752	Process	Regulation of circadian rhythm	ISS
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0045892	Process	Negative regulation of DNA-templated transcription	IDA	17892483, 17996965
GO:0045892	Process	Negative regulation of DNA-templated transcription	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	ISS
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0048511	Process	Rhythmic process	IEA
GO:0048512	Process	Circadian behavior	IEA
GO:0048512	Process	Circadian behavior	ISS
GO:0050727	Process	Regulation of inflammatory response	IEA
GO:0050727	Process	Regulation of inflammatory response	ISS
GO:0050728	Process	Negative regulation of inflammatory response	IEA
GO:0055088	Process	Lipid homeostasis	IEA
GO:0055088	Process	Lipid homeostasis	ISS
GO:0097009	Process	Energy homeostasis	IEA
GO:0097009	Process	Energy homeostasis	ISS
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:2001014	Process	Regulation of skeletal muscle cell differentiation	IEA
GO:2001014	Process	Regulation of skeletal muscle cell differentiation	ISS

Other IDs

• MIM: 602304
• HGNC: 7963
• e!Ensembl: ENSG00000174738

Protein

• UniProt ID: Q14995
• Protein name: Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear hormone receptor BD73) (Rev-erb alpha-related receptor) (RVR) (Rev-erb-beta) (V-erbA-related protein 1-related) (EAR-1R)
• Protein function: Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of th
• PDB: 2V0V, 2V7C, 3CQV, 4N73, 6WMQ, 6WMS
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00105	zf-C4	101 → 171	Zinc finger, C4 type (two domains)	Domain
  PF00104	Hormone_recep	399 → 578	Ligand-binding domain of nuclear hormone receptor	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. Expressed at high levels in the liver, adipose tissue, skeletal muscle and brain. Expression oscillates diurnally in the suprachiasmatic nucleus (SCN) of the hypothalamus as well as in peripheral tissues.
• Sequence:

  MEVNAGGVIAYISSSSSASSPASCHSEGSENSFQSSSSSVPSSPNSSNSDTNGNPKNGDL
  ANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHAC
  EGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIP
  KREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKS
  SSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDH
  CGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPI
  DGFSQNENKNSYLCNTGGRMHLVCPLSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFA
  KRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAG
  DLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLI
  MKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP

• Sequence length: 579

Pathways

KEGG:

Circadian rhythm

Reactome:

Nuclear Receptor transcription pathway

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Familial atrioventricular septal defect	Likely pathogenic	rs1358487339	RCV000851272

Associations from Text Mining
Disease Name	Relationship Type	References
Atherosclerosis	Associate	19243223
Breast Neoplasms	Associate	24785096, 25023698, 26074263, 39193850
Carcinoma Small Cell	Associate	33664492
Cardiomyopathy Restrictive	Stimulate	35912794
Diabetes Mellitus	Associate	19243223
Diabetes Mellitus Type 2	Associate	37904700
Disease	Associate	38255844
Drug Related Side Effects and Adverse Reactions	Associate	25023698
Inflammation	Associate	19243223
Melanoma	Associate	34783160
Melanoma Cutaneous Malignant	Associate	37373286
Mental Retardation Autosomal Dominant 1	Associate	25271084
Metabolic Syndrome	Associate	38255844
Neoplasms	Associate	19243223, 24785096, 38255844
Pre Eclampsia	Associate	36284122
Shock	Associate	36198442
Sleep Deprivation	Associate	23440187
Small Cell Lung Carcinoma	Associate	34741430