MED13 (mediator complex subunit 13)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9969 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Mediator complex subunit 13 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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MED13 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ARC250, DRIP250, HSPC221, MRD61, THRAP1, TRAP240 |
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Chromosome
Chromosome number
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17 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17q23.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activ |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q9UHV7 | |||||||||||||||
| Protein name | Mediator of RNA polymerase II transcription subunit 13 (Activator-recruited cofactor 250 kDa component) (ARC250) (Mediator complex subunit 13) (Thyroid hormone receptor-associated protein 1) (Thyroid hormone receptor-associated protein complex 240 kDa com | |||||||||||||||
| Protein function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RN | |||||||||||||||
| PDB | 8T9D , 8TQ2 , 8TQC , 8TQW , 8TRH | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:10198638}. | |||||||||||||||
| Sequence |
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| Sequence length | 2174 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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