MED13 (mediator complex subunit 13)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 9969 |
| Gene name | Mediator complex subunit 13 |
| Gene symbol | MED13 |
| Synonyms (NCBI Gene) |
ARC250DRIP250HSPC221MRD61THRAP1TRAP240
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| Chromosome | 17 |
| Chromosome location | 17q23.2 |
| Summary | This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activ |
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SNPs
SNP information provided by dbSNP.
12
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miRNA
miRNA information provided by mirtarbase database.
945
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
27
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9UHV7 | |||||||||||||||
| Protein name | Mediator of RNA polymerase II transcription subunit 13 (Activator-recruited cofactor 250 kDa component) (ARC250) (Mediator complex subunit 13) (Thyroid hormone receptor-associated protein 1) (Thyroid hormone receptor-associated protein complex 240 kDa com | |||||||||||||||
| Protein function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RN | |||||||||||||||
| PDB | 8T9D , 8TQ2 , 8TQC , 8TQW , 8TRH | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:10198638}. | |||||||||||||||
| Sequence |
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| Sequence length | 2174 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
167
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