OXSR1 (oxidative stress responsive kinase 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9943 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Oxidative stress responsive kinase 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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OXSR1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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OSR1 |
Chromosome
Chromosome number
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3 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3p22.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. [provided by RefSeq, Jul 2008] |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | O95747 | |||||||||||||||
Protein name | Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein) | |||||||||||||||
Protein function | Effector serine/threonine-protein kinase component of the WNK-SPAK/OSR1 kinase cascade, which is involved in various processes, such as ion transport, response to hypertonic stress and blood pressure (PubMed:16669787, PubMed:18270262, PubMed:213 | |||||||||||||||
PDB | 2V3S , 2VWI , 3DAK , 7OKW | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Ubiquitously expressed in all tissue examined. {ECO:0000269|PubMed:10083736}. | |||||||||||||||
Sequence |
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Sequence length | 527 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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