Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	9928
Gene name	Kinesin family member 14
Gene symbol	KIF14
Synonyms (NCBI Gene)	MCPH20MKS12
Chromosome	1
Chromosome location	1q32.1
Summary	This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and

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SNP ID	Visualize variation	Clinical significance	Consequence
rs786201012	CT>-	Pathogenic	Coding sequence variant, frameshift variant
rs786201013	T>A	Pathogenic	Coding sequence variant, stop gained
rs981349334	C>A	Pathogenic	Coding sequence variant, missense variant
rs1553253022	T>-	Pathogenic	Frameshift variant, coding sequence variant
rs1553254322	C>T	Pathogenic	Synonymous variant, coding sequence variant
rs1553259528	G>C	Pathogenic	Coding sequence variant, missense variant
rs1553259539	AAC>-	Pathogenic	Coding sequence variant, inframe deletion
rs1553264033	A>T	Pathogenic	Intron variant, coding sequence variant, 5 prime UTR variant, stop gained
rs1553264036	A>-	Pathogenic	Intron variant, frameshift variant, coding sequence variant, 5 prime UTR variant

360

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miRTarBase ID	miRNA	Experiments	Reference
MIRT016143	hsa-miR-615-3p	Sequencing	20371350
MIRT021036	hsa-miR-155-5p	Proteomics	18668040
MIRT024477	hsa-miR-215-5p	Microarray	19074876
MIRT026918	hsa-miR-192-5p	Microarray	19074876
MIRT032038	hsa-miR-16-5p	Proteomics	18668040
MIRT509232	hsa-miR-3133	PAR-CLIP	20371350
MIRT509231	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT509230	hsa-miR-4523	PAR-CLIP	20371350
MIRT509229	hsa-miR-4255	PAR-CLIP	20371350
MIRT509228	hsa-miR-6513-3p	PAR-CLIP	20371350
MIRT509226	hsa-miR-2116-5p	PAR-CLIP	20371350
MIRT509225	hsa-miR-22-5p	PAR-CLIP	20371350
MIRT509224	hsa-miR-4677-5p	PAR-CLIP	20371350
MIRT509232	hsa-miR-3133	PAR-CLIP	20371350
MIRT509231	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT509230	hsa-miR-4523	PAR-CLIP	20371350
MIRT509229	hsa-miR-4255	PAR-CLIP	20371350
MIRT509228	hsa-miR-6513-3p	PAR-CLIP	20371350
MIRT509227	hsa-miR-1976	PAR-CLIP	20371350
MIRT509226	hsa-miR-2116-5p	PAR-CLIP	20371350
MIRT509225	hsa-miR-22-5p	PAR-CLIP	20371350
MIRT509224	hsa-miR-4677-5p	PAR-CLIP	20371350
MIRT509232	hsa-miR-3133	PAR-CLIP	20371350
MIRT509231	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT509230	hsa-miR-4523	PAR-CLIP	20371350
MIRT509229	hsa-miR-4255	PAR-CLIP	20371350
MIRT509228	hsa-miR-6513-3p	PAR-CLIP	20371350
MIRT509226	hsa-miR-2116-5p	PAR-CLIP	20371350
MIRT509225	hsa-miR-22-5p	PAR-CLIP	20371350
MIRT509224	hsa-miR-4677-5p	PAR-CLIP	20371350
MIRT509232	hsa-miR-3133	PAR-CLIP	21572407
MIRT509231	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT509230	hsa-miR-4523	PAR-CLIP	21572407
MIRT509229	hsa-miR-4255	PAR-CLIP	21572407
MIRT509228	hsa-miR-6513-3p	PAR-CLIP	21572407
MIRT509227	hsa-miR-1976	PAR-CLIP	21572407
MIRT509226	hsa-miR-2116-5p	PAR-CLIP	21572407
MIRT509225	hsa-miR-22-5p	PAR-CLIP	21572407
MIRT509224	hsa-miR-4677-5p	PAR-CLIP	21572407
MIRT509232	hsa-miR-3133	PAR-CLIP	23446348
MIRT509231	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT509230	hsa-miR-4523	PAR-CLIP	23446348
MIRT509229	hsa-miR-4255	PAR-CLIP	23446348
MIRT509228	hsa-miR-6513-3p	PAR-CLIP	23446348
MIRT509227	hsa-miR-1976	PAR-CLIP	23446348
MIRT509226	hsa-miR-2116-5p	PAR-CLIP	23446348
MIRT509225	hsa-miR-22-5p	PAR-CLIP	23446348
MIRT509224	hsa-miR-4677-5p	PAR-CLIP	23446348
MIRT509232	hsa-miR-3133	PAR-CLIP	23446348
MIRT509231	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT509230	hsa-miR-4523	PAR-CLIP	23446348
MIRT509229	hsa-miR-4255	PAR-CLIP	23446348
MIRT509228	hsa-miR-6513-3p	PAR-CLIP	23446348
MIRT509227	hsa-miR-1976	PAR-CLIP	23446348
MIRT509226	hsa-miR-2116-5p	PAR-CLIP	23446348
MIRT509225	hsa-miR-22-5p	PAR-CLIP	23446348
MIRT509224	hsa-miR-4677-5p	PAR-CLIP	23446348
MIRT509232	hsa-miR-3133	PAR-CLIP	20371350
MIRT509231	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT509230	hsa-miR-4523	PAR-CLIP	20371350
MIRT509229	hsa-miR-4255	PAR-CLIP	20371350
MIRT509228	hsa-miR-6513-3p	PAR-CLIP	20371350
MIRT509226	hsa-miR-2116-5p	PAR-CLIP	20371350
MIRT509225	hsa-miR-22-5p	PAR-CLIP	20371350
MIRT509224	hsa-miR-4677-5p	PAR-CLIP	20371350
MIRT509232	hsa-miR-3133	PAR-CLIP	20371350
MIRT509231	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT509230	hsa-miR-4523	PAR-CLIP	20371350
MIRT509229	hsa-miR-4255	PAR-CLIP	20371350
MIRT509228	hsa-miR-6513-3p	PAR-CLIP	20371350
MIRT509227	hsa-miR-1976	PAR-CLIP	20371350
MIRT509226	hsa-miR-2116-5p	PAR-CLIP	20371350
MIRT509225	hsa-miR-22-5p	PAR-CLIP	20371350
MIRT509224	hsa-miR-4677-5p	PAR-CLIP	20371350
MIRT509232	hsa-miR-3133	PAR-CLIP	20371350
MIRT509231	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT509230	hsa-miR-4523	PAR-CLIP	20371350
MIRT509229	hsa-miR-4255	PAR-CLIP	20371350
MIRT509228	hsa-miR-6513-3p	PAR-CLIP	20371350
MIRT509226	hsa-miR-2116-5p	PAR-CLIP	20371350
MIRT509225	hsa-miR-22-5p	PAR-CLIP	20371350
MIRT509224	hsa-miR-4677-5p	PAR-CLIP	20371350
MIRT509232	hsa-miR-3133	PAR-CLIP	21572407
MIRT509231	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT509230	hsa-miR-4523	PAR-CLIP	21572407
MIRT509229	hsa-miR-4255	PAR-CLIP	21572407
MIRT509228	hsa-miR-6513-3p	PAR-CLIP	21572407
MIRT509227	hsa-miR-1976	PAR-CLIP	21572407
MIRT509226	hsa-miR-2116-5p	PAR-CLIP	21572407
MIRT509225	hsa-miR-22-5p	PAR-CLIP	21572407
MIRT509224	hsa-miR-4677-5p	PAR-CLIP	21572407
MIRT509232	hsa-miR-3133	PAR-CLIP	23446348
MIRT509231	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT509230	hsa-miR-4523	PAR-CLIP	23446348
MIRT509229	hsa-miR-4255	PAR-CLIP	23446348
MIRT509228	hsa-miR-6513-3p	PAR-CLIP	23446348
MIRT509227	hsa-miR-1976	PAR-CLIP	23446348
MIRT509226	hsa-miR-2116-5p	PAR-CLIP	23446348
MIRT509225	hsa-miR-22-5p	PAR-CLIP	23446348
MIRT509224	hsa-miR-4677-5p	PAR-CLIP	23446348
MIRT509232	hsa-miR-3133	PAR-CLIP	23446348
MIRT509231	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT509230	hsa-miR-4523	PAR-CLIP	23446348
MIRT509229	hsa-miR-4255	PAR-CLIP	23446348
MIRT509228	hsa-miR-6513-3p	PAR-CLIP	23446348
MIRT509227	hsa-miR-1976	PAR-CLIP	23446348
MIRT509226	hsa-miR-2116-5p	PAR-CLIP	23446348
MIRT509225	hsa-miR-22-5p	PAR-CLIP	23446348
MIRT509224	hsa-miR-4677-5p	PAR-CLIP	23446348
MIRT755334	hsa-miR-144-3p	Luciferase reporter assayqRT-PCRin vitro cullelar assays	38033864
MIRT1093327	hsa-miR-101	CLIP-seq
MIRT1093328	hsa-miR-1182	CLIP-seq
MIRT1093329	hsa-miR-1276	CLIP-seq
MIRT1093330	hsa-miR-1298	CLIP-seq
MIRT1093331	hsa-miR-144	CLIP-seq
MIRT1093332	hsa-miR-148a	CLIP-seq
MIRT1093333	hsa-miR-148b	CLIP-seq
MIRT1093334	hsa-miR-152	CLIP-seq
MIRT1093335	hsa-miR-154	CLIP-seq
MIRT1093336	hsa-miR-186	CLIP-seq
MIRT1093337	hsa-miR-1913	CLIP-seq
MIRT1093338	hsa-miR-193a-5p	CLIP-seq
MIRT1093339	hsa-miR-197	CLIP-seq
MIRT1093340	hsa-miR-200b	CLIP-seq
MIRT1093341	hsa-miR-200c	CLIP-seq
MIRT1093342	hsa-miR-221	CLIP-seq
MIRT1093343	hsa-miR-222	CLIP-seq
MIRT1093344	hsa-miR-223	CLIP-seq
MIRT1093345	hsa-miR-3143	CLIP-seq
MIRT1093346	hsa-miR-3145-3p	CLIP-seq
MIRT1093347	hsa-miR-3148	CLIP-seq
MIRT1093348	hsa-miR-3149	CLIP-seq
MIRT1093349	hsa-miR-3187-3p	CLIP-seq
MIRT1093350	hsa-miR-3190	CLIP-seq
MIRT1093351	hsa-miR-320a	CLIP-seq
MIRT1093352	hsa-miR-320b	CLIP-seq
MIRT1093353	hsa-miR-320c	CLIP-seq
MIRT1093354	hsa-miR-320d	CLIP-seq
MIRT1093355	hsa-miR-323b-3p	CLIP-seq
MIRT1093356	hsa-miR-324-3p	CLIP-seq
MIRT1093357	hsa-miR-3591-3p	CLIP-seq
MIRT1093358	hsa-miR-3607-3p	CLIP-seq
MIRT1093359	hsa-miR-3613-3p	CLIP-seq
MIRT1093360	hsa-miR-3617	CLIP-seq
MIRT1093361	hsa-miR-3622a-5p	CLIP-seq
MIRT1093362	hsa-miR-3646	CLIP-seq
MIRT1093363	hsa-miR-3655	CLIP-seq
MIRT1093364	hsa-miR-3671	CLIP-seq
MIRT1093365	hsa-miR-3686	CLIP-seq
MIRT1093366	hsa-miR-371-5p	CLIP-seq
MIRT1093367	hsa-miR-371b-5p	CLIP-seq
MIRT1093368	hsa-miR-3910	CLIP-seq
MIRT1093369	hsa-miR-411	CLIP-seq
MIRT1093370	hsa-miR-4269	CLIP-seq
MIRT1093371	hsa-miR-429	CLIP-seq
MIRT1093372	hsa-miR-4311	CLIP-seq
MIRT1093373	hsa-miR-4426	CLIP-seq
MIRT1093374	hsa-miR-4427	CLIP-seq
MIRT1093375	hsa-miR-4429	CLIP-seq
MIRT1093376	hsa-miR-4435	CLIP-seq
MIRT1093377	hsa-miR-4438	CLIP-seq
MIRT1093378	hsa-miR-4457	CLIP-seq
MIRT1093379	hsa-miR-4477a	CLIP-seq
MIRT1093380	hsa-miR-4484	CLIP-seq
MIRT1093381	hsa-miR-4633-5p	CLIP-seq
MIRT1093382	hsa-miR-4645-3p	CLIP-seq
MIRT1093383	hsa-miR-4647	CLIP-seq
MIRT1093384	hsa-miR-4662b	CLIP-seq
MIRT1093385	hsa-miR-4697-3p	CLIP-seq
MIRT1093386	hsa-miR-4699-5p	CLIP-seq
MIRT1093387	hsa-miR-4701-5p	CLIP-seq
MIRT1093388	hsa-miR-4707-3p	CLIP-seq
MIRT1093389	hsa-miR-4716-5p	CLIP-seq
MIRT1093390	hsa-miR-4724-5p	CLIP-seq
MIRT1093391	hsa-miR-4731-3p	CLIP-seq
MIRT1093392	hsa-miR-4753-3p	CLIP-seq
MIRT1093393	hsa-miR-4755-3p	CLIP-seq
MIRT1093394	hsa-miR-4772-5p	CLIP-seq
MIRT1093395	hsa-miR-4781-3p	CLIP-seq
MIRT1093396	hsa-miR-4801	CLIP-seq
MIRT1093397	hsa-miR-4802-3p	CLIP-seq
MIRT1093398	hsa-miR-483-5p	CLIP-seq
MIRT1093399	hsa-miR-488	CLIP-seq
MIRT1093400	hsa-miR-5095	CLIP-seq
MIRT1093401	hsa-miR-5096	CLIP-seq
MIRT1093402	hsa-miR-539	CLIP-seq
MIRT1093403	hsa-miR-543	CLIP-seq
MIRT1093404	hsa-miR-545	CLIP-seq
MIRT1093405	hsa-miR-548an	CLIP-seq
MIRT1093406	hsa-miR-548s	CLIP-seq
MIRT1093407	hsa-miR-548v	CLIP-seq
MIRT1093408	hsa-miR-570	CLIP-seq
MIRT1093409	hsa-miR-577	CLIP-seq
MIRT1093410	hsa-miR-578	CLIP-seq
MIRT1093411	hsa-miR-580	CLIP-seq
MIRT1093412	hsa-miR-583	CLIP-seq
MIRT1093413	hsa-miR-588	CLIP-seq
MIRT1093414	hsa-miR-607	CLIP-seq
MIRT1093415	hsa-miR-624	CLIP-seq
MIRT1093416	hsa-miR-641	CLIP-seq
MIRT1093417	hsa-miR-664	CLIP-seq
MIRT2025035	hsa-miR-106a	CLIP-seq
MIRT2025036	hsa-miR-106b	CLIP-seq
MIRT2025037	hsa-miR-1236	CLIP-seq
MIRT2025038	hsa-miR-1281	CLIP-seq
MIRT1093332	hsa-miR-148a	CLIP-seq
MIRT1093333	hsa-miR-148b	CLIP-seq
MIRT2025039	hsa-miR-150	CLIP-seq
MIRT1093334	hsa-miR-152	CLIP-seq
MIRT2025040	hsa-miR-17	CLIP-seq
MIRT1093337	hsa-miR-1913	CLIP-seq
MIRT2025041	hsa-miR-20a	CLIP-seq
MIRT2025042	hsa-miR-20b	CLIP-seq
MIRT1093344	hsa-miR-223	CLIP-seq
MIRT2025043	hsa-miR-302a	CLIP-seq
MIRT2025044	hsa-miR-302b	CLIP-seq
MIRT2025045	hsa-miR-302c	CLIP-seq
MIRT2025046	hsa-miR-302d	CLIP-seq
MIRT2025047	hsa-miR-302e	CLIP-seq
MIRT1093349	hsa-miR-3187-3p	CLIP-seq
MIRT1093356	hsa-miR-324-3p	CLIP-seq
MIRT1093357	hsa-miR-3591-3p	CLIP-seq
MIRT1093363	hsa-miR-3655	CLIP-seq
MIRT1093366	hsa-miR-371-5p	CLIP-seq
MIRT1093367	hsa-miR-371b-5p	CLIP-seq
MIRT2025048	hsa-miR-372	CLIP-seq
MIRT2025049	hsa-miR-373	CLIP-seq
MIRT1093376	hsa-miR-4435	CLIP-seq
MIRT2025050	hsa-miR-4445	CLIP-seq
MIRT1093378	hsa-miR-4457	CLIP-seq
MIRT2025051	hsa-miR-4532	CLIP-seq
MIRT1093385	hsa-miR-4697-3p	CLIP-seq
MIRT1093387	hsa-miR-4701-5p	CLIP-seq
MIRT1093388	hsa-miR-4707-3p	CLIP-seq
MIRT1093391	hsa-miR-4731-3p	CLIP-seq
MIRT1093393	hsa-miR-4755-3p	CLIP-seq
MIRT1093395	hsa-miR-4781-3p	CLIP-seq
MIRT1093396	hsa-miR-4801	CLIP-seq
MIRT2025052	hsa-miR-519a	CLIP-seq
MIRT2025053	hsa-miR-519b-3p	CLIP-seq
MIRT2025054	hsa-miR-519c-3p	CLIP-seq
MIRT2025055	hsa-miR-519d	CLIP-seq
MIRT2025056	hsa-miR-520a-3p	CLIP-seq
MIRT2025057	hsa-miR-520b	CLIP-seq
MIRT2025058	hsa-miR-520c-3p	CLIP-seq
MIRT2025059	hsa-miR-520d-3p	CLIP-seq
MIRT2025060	hsa-miR-520d-5p	CLIP-seq
MIRT2025061	hsa-miR-520e	CLIP-seq
MIRT2025062	hsa-miR-520g	CLIP-seq
MIRT2025063	hsa-miR-520h	CLIP-seq
MIRT2025064	hsa-miR-524-5p	CLIP-seq
MIRT1093406	hsa-miR-548s	CLIP-seq
MIRT1093408	hsa-miR-570	CLIP-seq
MIRT1093410	hsa-miR-578	CLIP-seq
MIRT1093413	hsa-miR-588	CLIP-seq
MIRT1093415	hsa-miR-624	CLIP-seq
MIRT2025065	hsa-miR-93	CLIP-seq
MIRT1093327	hsa-miR-101	CLIP-seq
MIRT2256145	hsa-miR-105	CLIP-seq
MIRT2025035	hsa-miR-106a	CLIP-seq
MIRT2025036	hsa-miR-106b	CLIP-seq
MIRT2256146	hsa-miR-1202	CLIP-seq
MIRT1093330	hsa-miR-1298	CLIP-seq
MIRT1093331	hsa-miR-144	CLIP-seq
MIRT2025040	hsa-miR-17	CLIP-seq
MIRT1093336	hsa-miR-186	CLIP-seq
MIRT1093339	hsa-miR-197	CLIP-seq
MIRT2025041	hsa-miR-20a	CLIP-seq
MIRT2025042	hsa-miR-20b	CLIP-seq
MIRT2256147	hsa-miR-300	CLIP-seq
MIRT2025043	hsa-miR-302a	CLIP-seq
MIRT2025044	hsa-miR-302b	CLIP-seq
MIRT2025045	hsa-miR-302c	CLIP-seq
MIRT2025046	hsa-miR-302d	CLIP-seq
MIRT2025047	hsa-miR-302e	CLIP-seq
MIRT1093348	hsa-miR-3149	CLIP-seq
MIRT1093349	hsa-miR-3187-3p	CLIP-seq
MIRT1093357	hsa-miR-3591-3p	CLIP-seq
MIRT1093364	hsa-miR-3671	CLIP-seq
MIRT2025048	hsa-miR-372	CLIP-seq
MIRT2025049	hsa-miR-373	CLIP-seq
MIRT2256148	hsa-miR-381	CLIP-seq
MIRT1093368	hsa-miR-3910	CLIP-seq
MIRT2256149	hsa-miR-3972	CLIP-seq
MIRT2256150	hsa-miR-3974	CLIP-seq
MIRT1093369	hsa-miR-411	CLIP-seq
MIRT2256151	hsa-miR-4256	CLIP-seq
MIRT1093376	hsa-miR-4435	CLIP-seq
MIRT1093378	hsa-miR-4457	CLIP-seq
MIRT1093380	hsa-miR-4484	CLIP-seq
MIRT2025051	hsa-miR-4532	CLIP-seq
MIRT1093387	hsa-miR-4701-5p	CLIP-seq
MIRT1093389	hsa-miR-4716-5p	CLIP-seq
MIRT1093391	hsa-miR-4731-3p	CLIP-seq
MIRT2256152	hsa-miR-4742-5p	CLIP-seq
MIRT1093392	hsa-miR-4753-3p	CLIP-seq
MIRT1093393	hsa-miR-4755-3p	CLIP-seq
MIRT1093395	hsa-miR-4781-3p	CLIP-seq
MIRT1093396	hsa-miR-4801	CLIP-seq
MIRT1093398	hsa-miR-483-5p	CLIP-seq
MIRT1093401	hsa-miR-5096	CLIP-seq
MIRT2025052	hsa-miR-519a	CLIP-seq
MIRT2025053	hsa-miR-519b-3p	CLIP-seq
MIRT2025054	hsa-miR-519c-3p	CLIP-seq
MIRT2025055	hsa-miR-519d	CLIP-seq
MIRT2025056	hsa-miR-520a-3p	CLIP-seq
MIRT2025057	hsa-miR-520b	CLIP-seq
MIRT2025058	hsa-miR-520c-3p	CLIP-seq
MIRT2025059	hsa-miR-520d-3p	CLIP-seq
MIRT2025060	hsa-miR-520d-5p	CLIP-seq
MIRT2025061	hsa-miR-520e	CLIP-seq
MIRT2025062	hsa-miR-520g	CLIP-seq
MIRT2025063	hsa-miR-520h	CLIP-seq
MIRT2025064	hsa-miR-524-5p	CLIP-seq
MIRT1093402	hsa-miR-539	CLIP-seq
MIRT1093405	hsa-miR-548an	CLIP-seq
MIRT1093406	hsa-miR-548s	CLIP-seq
MIRT1093408	hsa-miR-570	CLIP-seq
MIRT1093411	hsa-miR-580	CLIP-seq
MIRT1093413	hsa-miR-588	CLIP-seq
MIRT1093414	hsa-miR-607	CLIP-seq
MIRT1093415	hsa-miR-624	CLIP-seq
MIRT1093417	hsa-miR-664	CLIP-seq
MIRT2025065	hsa-miR-93	CLIP-seq
MIRT1093348	hsa-miR-3149	CLIP-seq
MIRT1093361	hsa-miR-3622a-5p	CLIP-seq
MIRT1093369	hsa-miR-411	CLIP-seq
MIRT1093377	hsa-miR-4438	CLIP-seq
MIRT1093398	hsa-miR-483-5p	CLIP-seq
MIRT1093400	hsa-miR-5095	CLIP-seq
MIRT1093404	hsa-miR-545	CLIP-seq
MIRT2465536	hsa-miR-1972	CLIP-seq
MIRT1093377	hsa-miR-4438	CLIP-seq
MIRT1093400	hsa-miR-5095	CLIP-seq
MIRT2557886	hsa-miR-1266	CLIP-seq
MIRT2025038	hsa-miR-1281	CLIP-seq
MIRT2025039	hsa-miR-150	CLIP-seq
MIRT1093337	hsa-miR-1913	CLIP-seq
MIRT2465536	hsa-miR-1972	CLIP-seq
MIRT1093356	hsa-miR-324-3p	CLIP-seq
MIRT1093361	hsa-miR-3622a-5p	CLIP-seq
MIRT2557887	hsa-miR-3664-3p	CLIP-seq
MIRT1093370	hsa-miR-4269	CLIP-seq
MIRT1093377	hsa-miR-4438	CLIP-seq
MIRT2557888	hsa-miR-4518	CLIP-seq
MIRT1093388	hsa-miR-4707-3p	CLIP-seq
MIRT2557889	hsa-miR-498	CLIP-seq
MIRT1093400	hsa-miR-5095	CLIP-seq
MIRT1093404	hsa-miR-545	CLIP-seq
MIRT2557886	hsa-miR-1266	CLIP-seq
MIRT2465536	hsa-miR-1972	CLIP-seq
MIRT1093361	hsa-miR-3622a-5p	CLIP-seq
MIRT2557887	hsa-miR-3664-3p	CLIP-seq
MIRT1093370	hsa-miR-4269	CLIP-seq
MIRT1093377	hsa-miR-4438	CLIP-seq
MIRT2557888	hsa-miR-4518	CLIP-seq
MIRT2557889	hsa-miR-498	CLIP-seq
MIRT1093400	hsa-miR-5095	CLIP-seq
MIRT1093401	hsa-miR-5096	CLIP-seq
MIRT1093404	hsa-miR-545	CLIP-seq

Show/Hide all (78)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0001558	Process	Regulation of cell growth	IMP	24854087
GO:0003777	Function	Microtubule motor activity	IBA
GO:0003777	Function	Microtubule motor activity	IEA
GO:0005515	Function	Protein binding	IPI	16431929, 16820410, 20309963
GO:0005524	Function	ATP binding	IEA
GO:0005524	Function	ATP binding	ISS
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005819	Component	Spindle	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005871	Component	Kinesin complex	IBA
GO:0005874	Component	Microtubule	IBA
GO:0005874	Component	Microtubule	IDA	23209302
GO:0005874	Component	Microtubule	IEA
GO:0005886	Component	Plasma membrane	IPI	24784001
GO:0007018	Process	Microtubule-based movement	IBA
GO:0007018	Process	Microtubule-based movement	IEA
GO:0007019	Process	Microtubule depolymerization	ISS
GO:0007080	Process	Mitotic metaphase chromosome alignment	IMP	15843429
GO:0008017	Function	Microtubule binding	IBA
GO:0008017	Function	Microtubule binding	IEA
GO:0008017	Function	Microtubule binding	ISS
GO:0008284	Process	Positive regulation of cell population proliferation	IDA	24784001
GO:0008284	Process	Positive regulation of cell population proliferation	IMP	24854087
GO:0008574	Function	Plus-end-directed microtubule motor activity	IEA
GO:0008574	Function	Plus-end-directed microtubule motor activity	ISS
GO:0010389	Process	Regulation of G2/M transition of mitotic cell cycle	IMP	24854087
GO:0015631	Function	Tubulin binding	IEA
GO:0015631	Function	Tubulin binding	ISS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016887	Function	ATP hydrolysis activity	IBA
GO:0016887	Function	ATP hydrolysis activity	IEA
GO:0016887	Function	ATP hydrolysis activity	ISS
GO:0019901	Function	Protein kinase binding	IPI	16431929, 24784001
GO:0021685	Process	Cerebellar granular layer structural organization	IEA
GO:0021685	Process	Cerebellar granular layer structural organization	ISS
GO:0021693	Process	Cerebellar Purkinje cell layer structural organization	IEA
GO:0021693	Process	Cerebellar Purkinje cell layer structural organization	ISS
GO:0021695	Process	Cerebellar cortex development	IEA
GO:0021695	Process	Cerebellar cortex development	ISS
GO:0021766	Process	Hippocampus development	IEA
GO:0021766	Process	Hippocampus development	ISS
GO:0021772	Process	Olfactory bulb development	IEA
GO:0021772	Process	Olfactory bulb development	ISS
GO:0021846	Process	Cell proliferation in forebrain	IEA
GO:0021846	Process	Cell proliferation in forebrain	ISS
GO:0021987	Process	Cerebral cortex development	IEA
GO:0021987	Process	Cerebral cortex development	ISS
GO:0030155	Process	Regulation of cell adhesion	IMP	23209302
GO:0030165	Function	PDZ domain binding	IDA	23209302
GO:0030334	Process	Regulation of cell migration	IMP	23209302
GO:0030496	Component	Midbody	IDA	16431929, 20309963
GO:0030496	Component	Midbody	IEA
GO:0031146	Process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IMP	24854087
GO:0031641	Process	Regulation of myelination	IEA
GO:0031641	Process	Regulation of myelination	ISS
GO:0032147	Process	Activation of protein kinase activity	IMP	24784001
GO:0032467	Process	Positive regulation of cytokinesis	IMP	16431929, 24854087
GO:0032487	Process	Regulation of Rap protein signal transduction	IMP	23209302
GO:0033624	Process	Negative regulation of integrin activation	IMP	23209302
GO:0034446	Process	Substrate adhesion-dependent cell spreading	IDA	23209302
GO:0043066	Process	Negative regulation of apoptotic process	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IMP	24784001
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IMP	24854087
GO:0043523	Process	Regulation of neuron apoptotic process	IEA
GO:0043523	Process	Regulation of neuron apoptotic process	ISS
GO:0043524	Process	Negative regulation of neuron apoptotic process	IEA
GO:0043524	Process	Negative regulation of neuron apoptotic process	ISS
GO:0045184	Process	Establishment of protein localization	IDA	23209302
GO:0051233	Component	Spindle midzone	IDA	16431929
GO:0051301	Process	Cell division	IEA
GO:0090543	Component	Flemming body	IDA
GO:1903429	Process	Regulation of cell maturation	IEA
GO:2000045	Process	Regulation of G1/S transition of mitotic cell cycle	IMP	24854087

MIM	HGNC	e!Ensembl
611279	19181	ENSG00000118193

Q15058

Protein name

Kinesin-like protein KIF14

Protein function

Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation an

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00225	Kinesin	364 → 701	Kinesin motor domain	Domain
PF16183	Kinesin_assoc	743 → 824	Kinesin-associated	Family
PF00498	FHA	825 → 891	FHA domain	Family

Sequence

MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV
RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT
LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP
LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT
QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA
PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT
VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ
TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR
KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS
SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN
LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW
LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK
AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK
LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL
SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH
PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI
AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ
EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT
VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL
EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS
GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE
RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL
MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ
AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ
HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA
PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE
SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG
VPKRVYELHGSSPAVSSEECTPSRIQWV

Sequence length

1648

Interactions

View interactions

	KEGG		Reactome
	Motor proteins		RHO GTPases activate CIT

Show/Hide Causal Diseases (5)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Clear cell carcinoma of kidney	Likely pathogenic	rs151249558	RCV005925488
Joubert syndrome and related disorders	Likely pathogenic	rs151249558, rs2527664861, rs764882468, rs2527565495, rs981349334	RCV003155454 RCV002302543 RCV003123487 RCV003123488 RCV005418240
KIF14-related disorder	Likely pathogenic	rs151249558	RCV003408047
Lethal fetal cerebrorenogenitourinary agenesis/hypoplasia syndrome	Pathogenic; Likely pathogenic	rs786201012, rs786201013, rs1660016633	RCV000162210 RCV000162211 RCV001283756
Microcephaly 20, primary, autosomal recessive	Likely pathogenic; Pathogenic	rs774318019, rs1558080206, rs2527564762, rs2527210283, rs1553264033, rs1553259539, rs1553254322, rs1553259528, rs981349334, rs1553264036, rs1553253022	RCV003147739 RCV003317908 RCV003445370 RCV004577424 RCV000599549 RCV000598713 RCV000599202 RCV000599574 RCV000598873 RCV000599230 RCV000599597

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Likely benign	rs144267058	RCV005908751
Cervical cancer	Benign; Likely benign	rs146996720, rs144267058	RCV005921369 RCV005908752
Gastric cancer	Likely benign; Benign	rs769164545, rs146095892	RCV005925955 RCV005904595
Malignant tumor of esophagus	Benign	rs146095892	RCV005904594

Show/Hide Text Mining Associations (39)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	31322267, 35810236
Adenocarcinoma of Lung	Stimulate	36227151
Astrocytoma	Associate	26536004
Autism Spectrum Disorder	Stimulate	26290361
Breast Neoplasms	Associate	16648480, 24784001
Carcinogenesis	Associate	26536004, 32623389
Carcinoma Hepatocellular	Associate	18803288, 24854087, 25106407
Carcinoma Ovarian Epithelial	Associate	28165566
Carcinoma Pancreatic Ductal	Associate	29483831
Carcinoma Renal Cell	Associate	34699322
Carcinoma Renal Cell	Inhibit	40186141
Colorectal Neoplasms	Associate	33190424, 34575892
Developmental Disabilities	Associate	29343805
Endometrial Neoplasms	Associate	33859719
Esophageal Squamous Cell Carcinoma	Associate	32546690, 34605738, 35156510
Fetal Diseases	Associate	29343805
Genomic Instability	Associate	34575892
Glioblastoma	Associate	26536004
Gliosarcoma	Associate	35381788
Intellectual Disability	Associate	29343805
Lung Neoplasms	Associate	31789390
Lymphatic Metastasis	Associate	27128470
Lymphatic Metastasis	Stimulate	30404039
Lymphoma Non Hodgkin	Associate	26933822
Medulloblastoma	Stimulate	28504687
Microcephaly	Associate	29343805
Neoplasm Metastasis	Associate	28165566, 30404039, 38070277, 40186141
Neoplasms	Associate	19190782, 24074379, 24626475, 24854087, 25106407, 27128470, 28165566, 28504687, 28525372, 29343805, 30404039, 32623389, 33190424, 34575892, 35439960, 36822388, 38070277, 40186141 View all (3 more)
Neoplasms	Stimulate	23542236, 26536004, 36227151
Optic Nerve Glioma	Associate	26536004
Ovarian Neoplasms	Associate	23542236, 24626475
Pancreatic Neoplasms	Associate	29483831
Prostatic Neoplasms	Associate	28525372, 36245556, 36822388
Retinoblastoma	Associate	19190782, 33217867
Stomach Neoplasms	Associate	30404039
Tissue Adhesions	Associate	40217245
Triple Negative Breast Neoplasms	Associate	24784001
Urinary Bladder Neoplasms	Associate	38070277
Uterine Cervical Neoplasms	Associate	27128470, 34495250, 35439960

KIF14 (kinesin family member 14)