Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9926
Gene name Gene Name - the full gene name approved by the HGNC.
Lysophosphatidylglycerol acyltransferase 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
LPGAT1
Synonyms (NCBI Gene) Gene synonyms aliases
FAM34A, FAM34A1, LPLAT7, NET8
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q32.3
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the lysophospholipid acyltransferase family. The encoded protein catalyzes the reacylation of lysophosphatidylglycerol to phosphatidylglycerol, a membrane phospholipid that is an important precursor for the synthesis of cardi
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020116 hsa-miR-130b-3p Sequencing 20371350
MIRT020554 hsa-miR-155-5p Proteomics 18668040
MIRT025088 hsa-miR-181a-5p Microarray 17612493
MIRT030680 hsa-miR-21-5p Microarray 18591254
MIRT031111 hsa-miR-19b-3p Sequencing 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003846 Function 2-acylglycerol O-acyltransferase activity ISS
GO:0005737 Component Cytoplasm IDA 10942595
GO:0005783 Component Endoplasmic reticulum IBA 21873635
GO:0005789 Component Endoplasmic reticulum membrane IMP 15485873
GO:0005789 Component Endoplasmic reticulum membrane TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
610473 28985 ENSG00000123684
Protein
UniProt ID Q92604
Protein name Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (2-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.62) (Acyl-CoA:monoacylglycerol acyltransferase LPGAT1) (EC 2.3.1.22) (Lysophospholipid acyltransferase 7) (LPLAT7) (EC 2.3.1.-) (Stearoyl-CoA:1-l
Protein function Lysophospholipid acyltransferase involved in fatty acyl chain remodeling of glycerophospholipids in the endoplasmic reticulum membrane (By similarity). Selectively catalyzes the transfer and esterification of saturated long-chain fatty acids fro
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01553 Acyltransferase 80 228 Acyltransferase Family
PF16076 Acyltransf_C 271 345 Acyltransferase C-terminus Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed in liver and placenta. Also expressed in peripheral blood, lung, kidney and brain. Detected at lower levels in colon. High expression is detected in brain and testis. {ECO:0000269|PubMed:15485873}.
Sequence
Sequence length 370
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Glycerophospholipid metabolism   Acyl chain remodelling of PG
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Mental depression Major Depressive Disorder 29495898 ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Colorectal Neoplasms Associate 31796117
Obesity Associate 23505186