LPGAT1 (lysophosphatidylglycerol acyltransferase 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9926 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Lysophosphatidylglycerol acyltransferase 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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LPGAT1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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FAM34A, FAM34A1, LPLAT7, NET8 |
Chromosome
Chromosome number
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1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1q32.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the lysophospholipid acyltransferase family. The encoded protein catalyzes the reacylation of lysophosphatidylglycerol to phosphatidylglycerol, a membrane phospholipid that is an important precursor for the synthesis of cardi |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q92604 | |||||||||||||||
Protein name | Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (2-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.62) (Acyl-CoA:monoacylglycerol acyltransferase LPGAT1) (EC 2.3.1.22) (Lysophospholipid acyltransferase 7) (LPLAT7) (EC 2.3.1.-) (Stearoyl-CoA:1-l | |||||||||||||||
Protein function | Lysophospholipid acyltransferase involved in fatty acyl chain remodeling of glycerophospholipids in the endoplasmic reticulum membrane (By similarity). Selectively catalyzes the transfer and esterification of saturated long-chain fatty acids fro | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Highly expressed in liver and placenta. Also expressed in peripheral blood, lung, kidney and brain. Detected at lower levels in colon. High expression is detected in brain and testis. {ECO:0000269|PubMed:15485873}. | |||||||||||||||
Sequence |
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Sequence length | 370 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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