Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9922
Gene name Gene Name - the full gene name approved by the HGNC.	IQ motif and Sec7 domain ArfGEF 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	IQSEC1
Synonyms (NCBI Gene) Gene synonyms aliases	ARF-GEP100, ARFGEP100, BRAG2, GEP100, IDDSSBA
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3p25.2-p25.1

Show/Hide all(409)

miRTarBase ID	miRNA	Experiments	Reference
MIRT044004	hsa-miR-378a-5p	CLASH	23622248
MIRT040506	hsa-miR-589-3p	CLASH	23622248
MIRT038915	hsa-miR-92a-1-5p	CLASH	23622248
MIRT649174	hsa-miR-4436b-3p	HITS-CLIP	23824327
MIRT649173	hsa-miR-4632-5p	HITS-CLIP	23824327
MIRT649171	hsa-miR-6735-5p	HITS-CLIP	23824327
MIRT649172	hsa-miR-6879-5p	HITS-CLIP	23824327
MIRT649170	hsa-miR-7843-5p	HITS-CLIP	23824327
MIRT649169	hsa-miR-4650-5p	HITS-CLIP	23824327
MIRT649168	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT649167	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT649166	hsa-miR-5193	HITS-CLIP	23824327
MIRT649165	hsa-miR-1914-5p	HITS-CLIP	23824327
MIRT649164	hsa-miR-4469	HITS-CLIP	23824327
MIRT649163	hsa-miR-3655	HITS-CLIP	23824327
MIRT649162	hsa-miR-3616-3p	HITS-CLIP	23824327
MIRT649161	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT649160	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT649159	hsa-miR-6721-5p	HITS-CLIP	23824327
MIRT649158	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT649157	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT649156	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT649155	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT440431	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT440430	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT440431	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT727430	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT727429	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT727428	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT727427	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT440430	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT649174	hsa-miR-4436b-3p	HITS-CLIP	23824327
MIRT649173	hsa-miR-4632-5p	HITS-CLIP	23824327
MIRT649171	hsa-miR-6735-5p	HITS-CLIP	23824327
MIRT649172	hsa-miR-6879-5p	HITS-CLIP	23824327
MIRT649170	hsa-miR-7843-5p	HITS-CLIP	23824327
MIRT649169	hsa-miR-4650-5p	HITS-CLIP	23824327
MIRT649168	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT649167	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT649166	hsa-miR-5193	HITS-CLIP	23824327
MIRT649165	hsa-miR-1914-5p	HITS-CLIP	23824327
MIRT649164	hsa-miR-4469	HITS-CLIP	23824327
MIRT649163	hsa-miR-3655	HITS-CLIP	23824327
MIRT649162	hsa-miR-3616-3p	HITS-CLIP	23824327
MIRT649161	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT649160	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT649159	hsa-miR-6721-5p	HITS-CLIP	23824327
MIRT649158	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT649157	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT649156	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT649155	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT1070074	hsa-miR-101	CLIP-seq
MIRT1070075	hsa-miR-103a	CLIP-seq
MIRT1070076	hsa-miR-106a	CLIP-seq
MIRT1070077	hsa-miR-106b	CLIP-seq
MIRT1070078	hsa-miR-107	CLIP-seq
MIRT1070079	hsa-miR-1179	CLIP-seq
MIRT1070080	hsa-miR-1197	CLIP-seq
MIRT1070081	hsa-miR-1227	CLIP-seq
MIRT1070082	hsa-miR-1231	CLIP-seq
MIRT1070083	hsa-miR-1234	CLIP-seq
MIRT1070084	hsa-miR-1253	CLIP-seq
MIRT1070085	hsa-miR-1270	CLIP-seq
MIRT1070086	hsa-miR-1276	CLIP-seq
MIRT1070087	hsa-miR-128	CLIP-seq
MIRT1070088	hsa-miR-1284	CLIP-seq
MIRT1070089	hsa-miR-129-5p	CLIP-seq
MIRT1070090	hsa-miR-133a	CLIP-seq
MIRT1070091	hsa-miR-133b	CLIP-seq
MIRT1070092	hsa-miR-1343	CLIP-seq
MIRT1070093	hsa-miR-143	CLIP-seq
MIRT1070094	hsa-miR-144	CLIP-seq
MIRT1070095	hsa-miR-17	CLIP-seq
MIRT1070096	hsa-miR-185	CLIP-seq
MIRT1070097	hsa-miR-18a	CLIP-seq
MIRT1070098	hsa-miR-18b	CLIP-seq
MIRT1070099	hsa-miR-1910	CLIP-seq
MIRT1070100	hsa-miR-1915	CLIP-seq
MIRT1070101	hsa-miR-197	CLIP-seq
MIRT1070102	hsa-miR-1976	CLIP-seq
MIRT1070103	hsa-miR-2052	CLIP-seq
MIRT1070104	hsa-miR-20a	CLIP-seq
MIRT1070105	hsa-miR-20b	CLIP-seq
MIRT1070106	hsa-miR-2110	CLIP-seq
MIRT1070107	hsa-miR-219-5p	CLIP-seq
MIRT1070108	hsa-miR-2681	CLIP-seq
MIRT1070109	hsa-miR-27a	CLIP-seq
MIRT1070110	hsa-miR-27b	CLIP-seq
MIRT1070111	hsa-miR-2909	CLIP-seq
MIRT1070112	hsa-miR-296-3p	CLIP-seq
MIRT1070113	hsa-miR-297	CLIP-seq
MIRT1070114	hsa-miR-3115	CLIP-seq
MIRT1070115	hsa-miR-3126-5p	CLIP-seq
MIRT1070116	hsa-miR-3147	CLIP-seq
MIRT1070117	hsa-miR-3149	CLIP-seq
MIRT1070118	hsa-miR-3150a-3p	CLIP-seq
MIRT1070119	hsa-miR-3154	CLIP-seq
MIRT1070120	hsa-miR-3166	CLIP-seq
MIRT1070121	hsa-miR-3170	CLIP-seq
MIRT1070122	hsa-miR-3175	CLIP-seq
MIRT1070123	hsa-miR-329	CLIP-seq
MIRT1070124	hsa-miR-331-5p	CLIP-seq
MIRT1070125	hsa-miR-337-3p	CLIP-seq
MIRT1070126	hsa-miR-342-3p	CLIP-seq
MIRT1070127	hsa-miR-3609	CLIP-seq
MIRT1070128	hsa-miR-3615	CLIP-seq
MIRT1070129	hsa-miR-3617	CLIP-seq
MIRT1070130	hsa-miR-362-3p	CLIP-seq
MIRT1070131	hsa-miR-3647-3p	CLIP-seq
MIRT1070132	hsa-miR-3689a-3p	CLIP-seq
MIRT1070133	hsa-miR-3689c	CLIP-seq
MIRT1070134	hsa-miR-375	CLIP-seq
MIRT1070135	hsa-miR-377	CLIP-seq
MIRT1070136	hsa-miR-384	CLIP-seq
MIRT1070137	hsa-miR-3917	CLIP-seq
MIRT1070138	hsa-miR-3942-5p	CLIP-seq
MIRT1070139	hsa-miR-4260	CLIP-seq
MIRT1070140	hsa-miR-4279	CLIP-seq
MIRT1070141	hsa-miR-4283	CLIP-seq
MIRT1070142	hsa-miR-4284	CLIP-seq
MIRT1070143	hsa-miR-4288	CLIP-seq
MIRT1070144	hsa-miR-4306	CLIP-seq
MIRT1070145	hsa-miR-4326	CLIP-seq
MIRT1070146	hsa-miR-4425	CLIP-seq
MIRT1070147	hsa-miR-4427	CLIP-seq
MIRT1070148	hsa-miR-4445	CLIP-seq
MIRT1070149	hsa-miR-4448	CLIP-seq
MIRT1070150	hsa-miR-4475	CLIP-seq
MIRT1070151	hsa-miR-4480	CLIP-seq
MIRT1070152	hsa-miR-4514	CLIP-seq
MIRT1070153	hsa-miR-4531	CLIP-seq
MIRT1070154	hsa-miR-4633-3p	CLIP-seq
MIRT1070155	hsa-miR-4641	CLIP-seq
MIRT1070156	hsa-miR-4644	CLIP-seq
MIRT1070157	hsa-miR-4645-5p	CLIP-seq
MIRT1070158	hsa-miR-4659a-3p	CLIP-seq
MIRT1070159	hsa-miR-4659b-3p	CLIP-seq
MIRT1070160	hsa-miR-4662a-5p	CLIP-seq
MIRT1070161	hsa-miR-4673	CLIP-seq
MIRT1070162	hsa-miR-4676-5p	CLIP-seq
MIRT1070163	hsa-miR-4680-3p	CLIP-seq
MIRT1070164	hsa-miR-4683	CLIP-seq
MIRT1070165	hsa-miR-4692	CLIP-seq
MIRT1070166	hsa-miR-4694-5p	CLIP-seq
MIRT1070167	hsa-miR-4700-3p	CLIP-seq
MIRT1070168	hsa-miR-4703-5p	CLIP-seq
MIRT1070169	hsa-miR-4722-3p	CLIP-seq
MIRT1070170	hsa-miR-4726-3p	CLIP-seq
MIRT1070171	hsa-miR-4727-5p	CLIP-seq
MIRT1070172	hsa-miR-4728-5p	CLIP-seq
MIRT1070173	hsa-miR-4731-3p	CLIP-seq
MIRT1070174	hsa-miR-4735-3p	CLIP-seq
MIRT1070175	hsa-miR-4749-3p	CLIP-seq
MIRT1070176	hsa-miR-4764-5p	CLIP-seq
MIRT1070177	hsa-miR-4770	CLIP-seq
MIRT1070178	hsa-miR-4781-3p	CLIP-seq
MIRT1070179	hsa-miR-4782-3p	CLIP-seq
MIRT1070180	hsa-miR-4790-3p	CLIP-seq
MIRT1070181	hsa-miR-4793-5p	CLIP-seq
MIRT1070182	hsa-miR-4796-3p	CLIP-seq
MIRT1070183	hsa-miR-4801	CLIP-seq
MIRT1070184	hsa-miR-4802-5p	CLIP-seq
MIRT1070185	hsa-miR-490-5p	CLIP-seq
MIRT1070186	hsa-miR-508-3p	CLIP-seq
MIRT1070187	hsa-miR-519d	CLIP-seq
MIRT1070188	hsa-miR-541	CLIP-seq
MIRT1070189	hsa-miR-548ag	CLIP-seq
MIRT1070190	hsa-miR-548ah	CLIP-seq
MIRT1070191	hsa-miR-548ai	CLIP-seq
MIRT1070192	hsa-miR-552	CLIP-seq
MIRT1070193	hsa-miR-575	CLIP-seq
MIRT1070194	hsa-miR-584	CLIP-seq
MIRT1070195	hsa-miR-601	CLIP-seq
MIRT1070196	hsa-miR-618	CLIP-seq
MIRT1070197	hsa-miR-620	CLIP-seq
MIRT1070198	hsa-miR-632	CLIP-seq
MIRT1070199	hsa-miR-641	CLIP-seq
MIRT1070200	hsa-miR-654-5p	CLIP-seq
MIRT1070201	hsa-miR-676	CLIP-seq
MIRT1070202	hsa-miR-93	CLIP-seq
MIRT1070203	hsa-miR-939	CLIP-seq
MIRT1070076	hsa-miR-106a	CLIP-seq
MIRT1070077	hsa-miR-106b	CLIP-seq
MIRT1070085	hsa-miR-1270	CLIP-seq
MIRT1070204	hsa-miR-1294	CLIP-seq
MIRT1070205	hsa-miR-138	CLIP-seq
MIRT1070206	hsa-miR-151-3p	CLIP-seq
MIRT1070095	hsa-miR-17	CLIP-seq
MIRT1070207	hsa-miR-190	CLIP-seq
MIRT1070208	hsa-miR-190b	CLIP-seq
MIRT1070209	hsa-miR-1914	CLIP-seq
MIRT1070104	hsa-miR-20a	CLIP-seq
MIRT1070105	hsa-miR-20b	CLIP-seq
MIRT1070210	hsa-miR-302a	CLIP-seq
MIRT1070211	hsa-miR-302b	CLIP-seq
MIRT1070212	hsa-miR-302c	CLIP-seq
MIRT1070213	hsa-miR-302d	CLIP-seq
MIRT1070214	hsa-miR-302e	CLIP-seq
MIRT1070215	hsa-miR-3150b-3p	CLIP-seq
MIRT1070216	hsa-miR-326	CLIP-seq
MIRT1070217	hsa-miR-330-5p	CLIP-seq
MIRT1070218	hsa-miR-3613-5p	CLIP-seq
MIRT1070219	hsa-miR-3678-3p	CLIP-seq
MIRT1070132	hsa-miR-3689a-3p	CLIP-seq
MIRT1070133	hsa-miR-3689c	CLIP-seq
MIRT1070220	hsa-miR-372	CLIP-seq
MIRT1070221	hsa-miR-373	CLIP-seq
MIRT1070140	hsa-miR-4279	CLIP-seq
MIRT1070222	hsa-miR-4316	CLIP-seq
MIRT1070164	hsa-miR-4683	CLIP-seq
MIRT1070223	hsa-miR-4689	CLIP-seq
MIRT1070224	hsa-miR-4695-3p	CLIP-seq
MIRT1070172	hsa-miR-4728-5p	CLIP-seq
MIRT1070225	hsa-miR-4760-3p	CLIP-seq
MIRT1070176	hsa-miR-4764-5p	CLIP-seq
MIRT1070226	hsa-miR-4779	CLIP-seq
MIRT1070227	hsa-miR-4784	CLIP-seq
MIRT1070228	hsa-miR-495	CLIP-seq
MIRT1070229	hsa-miR-516b	CLIP-seq
MIRT1070187	hsa-miR-519d	CLIP-seq
MIRT1070230	hsa-miR-520a-3p	CLIP-seq
MIRT1070231	hsa-miR-520b	CLIP-seq
MIRT1070232	hsa-miR-520c-3p	CLIP-seq
MIRT1070233	hsa-miR-520d-3p	CLIP-seq
MIRT1070234	hsa-miR-520e	CLIP-seq
MIRT1070235	hsa-miR-520f	CLIP-seq
MIRT1070236	hsa-miR-520g	CLIP-seq
MIRT1070237	hsa-miR-520h	CLIP-seq
MIRT1070238	hsa-miR-582-5p	CLIP-seq
MIRT1070197	hsa-miR-620	CLIP-seq
MIRT1070239	hsa-miR-636	CLIP-seq
MIRT1070240	hsa-miR-642a	CLIP-seq
MIRT1070241	hsa-miR-664	CLIP-seq
MIRT1070201	hsa-miR-676	CLIP-seq
MIRT1070202	hsa-miR-93	CLIP-seq
MIRT1070075	hsa-miR-103a	CLIP-seq
MIRT1070076	hsa-miR-106a	CLIP-seq
MIRT1070077	hsa-miR-106b	CLIP-seq
MIRT1070078	hsa-miR-107	CLIP-seq
MIRT1070080	hsa-miR-1197	CLIP-seq
MIRT2017206	hsa-miR-1224-5p	CLIP-seq
MIRT1070081	hsa-miR-1227	CLIP-seq
MIRT1070082	hsa-miR-1231	CLIP-seq
MIRT2017207	hsa-miR-125a-5p	CLIP-seq
MIRT2017208	hsa-miR-125b	CLIP-seq
MIRT1070085	hsa-miR-1270	CLIP-seq
MIRT2017209	hsa-miR-1271	CLIP-seq
MIRT1070087	hsa-miR-128	CLIP-seq
MIRT2017210	hsa-miR-1291	CLIP-seq
MIRT1070093	hsa-miR-143	CLIP-seq
MIRT2017211	hsa-miR-146b-3p	CLIP-seq
MIRT2017212	hsa-miR-147	CLIP-seq
MIRT1070095	hsa-miR-17	CLIP-seq
MIRT1070099	hsa-miR-1910	CLIP-seq
MIRT1070102	hsa-miR-1976	CLIP-seq
MIRT1070103	hsa-miR-2052	CLIP-seq
MIRT1070104	hsa-miR-20a	CLIP-seq
MIRT1070105	hsa-miR-20b	CLIP-seq
MIRT2017213	hsa-miR-2115	CLIP-seq
MIRT2017214	hsa-miR-221	CLIP-seq
MIRT2017215	hsa-miR-222	CLIP-seq
MIRT2017216	hsa-miR-2277-3p	CLIP-seq
MIRT2017217	hsa-miR-2392	CLIP-seq
MIRT1070113	hsa-miR-297	CLIP-seq
MIRT2017218	hsa-miR-3064-3p	CLIP-seq
MIRT2017219	hsa-miR-3074-3p	CLIP-seq
MIRT1070114	hsa-miR-3115	CLIP-seq
MIRT1070115	hsa-miR-3126-5p	CLIP-seq
MIRT2017220	hsa-miR-3131	CLIP-seq
MIRT1070117	hsa-miR-3149	CLIP-seq
MIRT1070215	hsa-miR-3150b-3p	CLIP-seq
MIRT1070121	hsa-miR-3170	CLIP-seq
MIRT2017221	hsa-miR-3173-5p	CLIP-seq
MIRT1070123	hsa-miR-329	CLIP-seq
MIRT1070125	hsa-miR-337-3p	CLIP-seq
MIRT1070126	hsa-miR-342-3p	CLIP-seq
MIRT1070127	hsa-miR-3609	CLIP-seq
MIRT1070128	hsa-miR-3615	CLIP-seq
MIRT1070129	hsa-miR-3617	CLIP-seq
MIRT2017222	hsa-miR-3620	CLIP-seq
MIRT1070130	hsa-miR-362-3p	CLIP-seq
MIRT2017223	hsa-miR-3659	CLIP-seq
MIRT2017224	hsa-miR-3660	CLIP-seq
MIRT2017225	hsa-miR-3686	CLIP-seq
MIRT2017226	hsa-miR-369-3p	CLIP-seq
MIRT2017227	hsa-miR-370	CLIP-seq
MIRT2017228	hsa-miR-371b-5p	CLIP-seq
MIRT2017229	hsa-miR-374a	CLIP-seq
MIRT2017230	hsa-miR-374b	CLIP-seq
MIRT1070134	hsa-miR-375	CLIP-seq
MIRT1070135	hsa-miR-377	CLIP-seq
MIRT2017231	hsa-miR-380	CLIP-seq
MIRT1070137	hsa-miR-3917	CLIP-seq
MIRT2017232	hsa-miR-4252	CLIP-seq
MIRT1070139	hsa-miR-4260	CLIP-seq
MIRT2017233	hsa-miR-4268	CLIP-seq
MIRT1070143	hsa-miR-4288	CLIP-seq
MIRT2017234	hsa-miR-4302	CLIP-seq
MIRT2017235	hsa-miR-4310	CLIP-seq
MIRT2017236	hsa-miR-4312	CLIP-seq
MIRT2017237	hsa-miR-4319	CLIP-seq
MIRT2017238	hsa-miR-4418	CLIP-seq
MIRT2017239	hsa-miR-4419a	CLIP-seq
MIRT2017240	hsa-miR-4421	CLIP-seq
MIRT1070147	hsa-miR-4427	CLIP-seq
MIRT2017241	hsa-miR-4436a	CLIP-seq
MIRT2017242	hsa-miR-4438	CLIP-seq
MIRT2017243	hsa-miR-4447	CLIP-seq
MIRT1070149	hsa-miR-4448	CLIP-seq
MIRT2017244	hsa-miR-4472	CLIP-seq
MIRT2017245	hsa-miR-4510	CLIP-seq
MIRT2017246	hsa-miR-4522	CLIP-seq
MIRT2017247	hsa-miR-4526	CLIP-seq
MIRT2017248	hsa-miR-4528	CLIP-seq
MIRT1070153	hsa-miR-4531	CLIP-seq
MIRT2017249	hsa-miR-4658	CLIP-seq
MIRT1070158	hsa-miR-4659a-3p	CLIP-seq
MIRT1070159	hsa-miR-4659b-3p	CLIP-seq
MIRT1070160	hsa-miR-4662a-5p	CLIP-seq
MIRT1070162	hsa-miR-4676-5p	CLIP-seq
MIRT1070163	hsa-miR-4680-3p	CLIP-seq
MIRT1070164	hsa-miR-4683	CLIP-seq
MIRT2017250	hsa-miR-4684-3p	CLIP-seq
MIRT2017251	hsa-miR-4690-3p	CLIP-seq
MIRT2017252	hsa-miR-4708-5p	CLIP-seq
MIRT2017253	hsa-miR-4710	CLIP-seq
MIRT2017254	hsa-miR-4714-5p	CLIP-seq
MIRT2017255	hsa-miR-4717-3p	CLIP-seq
MIRT1070171	hsa-miR-4727-5p	CLIP-seq
MIRT2017256	hsa-miR-4732-3p	CLIP-seq
MIRT2017257	hsa-miR-4742-3p	CLIP-seq
MIRT1070175	hsa-miR-4749-3p	CLIP-seq
MIRT2017258	hsa-miR-4751	CLIP-seq
MIRT1070177	hsa-miR-4770	CLIP-seq
MIRT2017259	hsa-miR-4778-5p	CLIP-seq
MIRT1070227	hsa-miR-4784	CLIP-seq
MIRT1070182	hsa-miR-4796-3p	CLIP-seq
MIRT2017260	hsa-miR-4802-3p	CLIP-seq
MIRT2017261	hsa-miR-509-3-5p	CLIP-seq
MIRT2017262	hsa-miR-509-5p	CLIP-seq
MIRT1070229	hsa-miR-516b	CLIP-seq
MIRT1070187	hsa-miR-519d	CLIP-seq
MIRT2017263	hsa-miR-545	CLIP-seq
MIRT1070189	hsa-miR-548ag	CLIP-seq
MIRT1070190	hsa-miR-548ah	CLIP-seq
MIRT1070191	hsa-miR-548ai	CLIP-seq
MIRT2017264	hsa-miR-567	CLIP-seq
MIRT2017265	hsa-miR-574-5p	CLIP-seq
MIRT1070193	hsa-miR-575	CLIP-seq
MIRT2017266	hsa-miR-576-3p	CLIP-seq
MIRT2017267	hsa-miR-611	CLIP-seq
MIRT1070197	hsa-miR-620	CLIP-seq
MIRT2017268	hsa-miR-621	CLIP-seq
MIRT1070198	hsa-miR-632	CLIP-seq
MIRT1070199	hsa-miR-641	CLIP-seq
MIRT1070240	hsa-miR-642a	CLIP-seq
MIRT2017269	hsa-miR-665	CLIP-seq
MIRT2017270	hsa-miR-670	CLIP-seq
MIRT2017271	hsa-miR-767-3p	CLIP-seq
MIRT2017272	hsa-miR-874	CLIP-seq
MIRT2017273	hsa-miR-885-3p	CLIP-seq
MIRT2017274	hsa-miR-890	CLIP-seq
MIRT1070202	hsa-miR-93	CLIP-seq
MIRT2017275	hsa-miR-96	CLIP-seq
MIRT1070075	hsa-miR-103a	CLIP-seq
MIRT1070078	hsa-miR-107	CLIP-seq
MIRT1070080	hsa-miR-1197	CLIP-seq
MIRT1070081	hsa-miR-1227	CLIP-seq
MIRT2249164	hsa-miR-1265	CLIP-seq
MIRT2249165	hsa-miR-1286	CLIP-seq
MIRT2249166	hsa-miR-1299	CLIP-seq
MIRT1070205	hsa-miR-138	CLIP-seq
MIRT1070096	hsa-miR-185	CLIP-seq
MIRT2017213	hsa-miR-2115	CLIP-seq
MIRT2017217	hsa-miR-2392	CLIP-seq
MIRT2017218	hsa-miR-3064-3p	CLIP-seq
MIRT1070120	hsa-miR-3166	CLIP-seq
MIRT1070123	hsa-miR-329	CLIP-seq
MIRT1070129	hsa-miR-3617	CLIP-seq
MIRT1070130	hsa-miR-362-3p	CLIP-seq
MIRT2017228	hsa-miR-371b-5p	CLIP-seq
MIRT2017231	hsa-miR-380	CLIP-seq
MIRT1070144	hsa-miR-4306	CLIP-seq
MIRT2249167	hsa-miR-4327	CLIP-seq
MIRT2017239	hsa-miR-4419a	CLIP-seq
MIRT2249168	hsa-miR-4495	CLIP-seq
MIRT2249169	hsa-miR-4503	CLIP-seq
MIRT2017245	hsa-miR-4510	CLIP-seq
MIRT2249170	hsa-miR-451b	CLIP-seq
MIRT2249171	hsa-miR-4534	CLIP-seq
MIRT1070154	hsa-miR-4633-3p	CLIP-seq
MIRT1070156	hsa-miR-4644	CLIP-seq
MIRT1070224	hsa-miR-4695-3p	CLIP-seq
MIRT2249172	hsa-miR-4698	CLIP-seq
MIRT2249173	hsa-miR-4722-5p	CLIP-seq
MIRT2249174	hsa-miR-508-5p	CLIP-seq
MIRT2017266	hsa-miR-576-3p	CLIP-seq
MIRT1070199	hsa-miR-641	CLIP-seq
MIRT2249175	hsa-miR-651	CLIP-seq
MIRT2249176	hsa-miR-766	CLIP-seq
MIRT2249177	hsa-miR-875-3p	CLIP-seq
MIRT1070205	hsa-miR-138	CLIP-seq
MIRT2552730	hsa-miR-4766-5p	CLIP-seq
MIRT2682902	hsa-miR-3682-5p	CLIP-seq
MIRT2017231	hsa-miR-380	CLIP-seq
MIRT2682903	hsa-miR-4315	CLIP-seq
MIRT2249168	hsa-miR-4495	CLIP-seq
MIRT2682904	hsa-miR-4790-5p	CLIP-seq
MIRT2682905	hsa-miR-888	CLIP-seq

Show/Hide all(19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IBA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IEA
GO:0005515	Function	Protein binding	IPI	27265506, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA
GO:0005829	Component	Cytosol	IDA
GO:0008021	Component	Synaptic vesicle	IEA
GO:0008289	Function	Lipid binding	IEA
GO:0014069	Component	Postsynaptic density	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0030036	Process	Actin cytoskeleton organization	IBA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0032012	Process	Regulation of ARF protein signal transduction	IEA
GO:0045202	Component	Synapse	IEA
GO:0051549	Process	Positive regulation of keratinocyte migration	ISS
GO:0060996	Process	Dendritic spine development	ISS
GO:0120183	Process	Positive regulation of focal adhesion disassembly	ISS

MIM	HGNC	e!Ensembl
610166	29112	ENSG00000144711

Protein

UniProt ID

Q6DN90

Protein name

IQ motif and SEC7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein) (BRAG2)

Protein function

Guanine nucleotide exchange factor for ARF1 and ARF6 (PubMed:11226253, PubMed:24058294). Guanine nucleotide exchange factor activity is enhanced by lipid binding (PubMed:24058294). Accelerates GTP binding by ARFs of all three classes. Guanine nu

PDB

3QWM , 4C0A , 5NLV , 5NLY , 6FNE , 7VMB

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01369	Sec7	524 → 712	Sec7 domain	Domain
PF16453	IQ_SEC7_PH	743 → 879	PH domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis. {ECO:0000269|PubMed:11226253, ECO:0000269|Pub

Sequence

MWCLHCNSERTQSLLELELDSGVEGEAPSSETGTSLDSPSAYPQGPLVPGSSLSPDHYEH
TSVGAYGLYSGPPGQQQRTRRPKLQHSTSILRKQAEEEAIKRSRSLSESYELSSDLQDKQ
VEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLRSSMSENRMSRRIVLSNMRMQFS
FEGPEKVHSSYFEGKQVSVTNDGSQLGALVSPECGDLSEPTTLKSPAPSSDFADAITELE
DAFSRQVKSLAESIDDALNCRSLHTEEAPALDAARARDTEPQTALHGMDHRKLDEMTASY
SDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRAGGAAPDYWALAHKEDKADTDTSCR
STPSLERQEQRLRVEHLPLLTIEPPSDSSVDLSDRSERGSLKRQSAYERSLGGQQGSPKH
GPHSGAPKSLPREEPELRPRPPRPLDSHLAINGSANRQSKSESDYSDGDNDSINSTSNSN
DTINCSSESSSRDSLREQTLSKQTYHKEARNSWDSPAFSNDVIRKRHYRIGLNLFNKKPE
KGVQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFS
TMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCICNPGVVRQFRNPDTIFILAFAII
LLNTDMYSPNVKPERKMKLEDFIKNLRGVDDGEDIPREMLMGIYERIRKRELKTNEDHVS
QVQKVEKLIVGKKPIGSLHPGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFL
FNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSSVPGADIKVLI
NFNAPNPQDRKKFTDDLRESIAEVQEMEKHRIESELEKQKGVVRPSMSQCSSLKKESGNG
TLSRACLDDSYASGEGLKRSALSSSLRDLSEAGKRGRRSSAGSLESNVEFQPFEPLQPSV
LCS

Sequence length

963

Interactions

View interactions

	KEGG
	Endocytosis

Show/Hide Causal Diseases (1)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Mental retardation	Intellectual developmental disorder with short stature and behavioral abnormalities	rs765723607, rs758170522	N/A

Show/Hide Unknown Diseases (4)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Glioblastoma	Glioblastoma	N/A	N/A	GWAS
Metabolic Syndrome	Metabolic syndrome	N/A	N/A	GWAS
Non-Syndromic Intellectual Disability	autosomal recessive non-syndromic intellectual disability	N/A	N/A	GenCC

Show/Hide Text Mining Associations (16)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	21966491
Atrophy	Associate	33319642
Breast Neoplasms	Associate	23747719, 24116160
Carcinoma Hepatocellular	Associate	22701712
Carcinoma Non Small Cell Lung	Associate	22491060
Carcinoma Squamous Cell	Associate	22491060
Epilepsy	Associate	37246165
Fibrosis	Associate	24516231, 33319642
Glomerulonephritis IGA	Associate	33319642
Kidney Neoplasms	Associate	24516231
Lymphatic Metastasis	Associate	21966491
Neoplasm Metastasis	Associate	22491060
Neoplasm Recurrence Local	Associate	24116160
Neoplasms	Associate	21966491, 22491060
Ovarian Neoplasms	Associate	23202957
Periodontitis	Associate	35179257

IQSEC1 (IQ motif and Sec7 domain ArfGEF 1)