Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9920
Gene name Gene Name - the full gene name approved by the HGNC.	Kelch repeat and BTB domain containing 11
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	KBTBD11
Synonyms (NCBI Gene) Gene synonyms aliases	KLHDC7C
Chromosome Chromosome number	8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	8p23.3

Show/Hide all(208)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016377	hsa-miR-193b-3p	Microarray	20304954
MIRT024631	hsa-miR-215-5p	Microarray	19074876
MIRT026418	hsa-miR-192-5p	Microarray	19074876
MIRT714300	hsa-miR-128-3p	HITS-CLIP	19536157
MIRT714299	hsa-miR-216a-3p	HITS-CLIP	19536157
MIRT714298	hsa-miR-3681-3p	HITS-CLIP	19536157
MIRT714297	hsa-miR-6733-3p	HITS-CLIP	19536157
MIRT714296	hsa-miR-4722-3p	HITS-CLIP	19536157
MIRT714295	hsa-miR-6727-3p	HITS-CLIP	19536157
MIRT714294	hsa-miR-6747-3p	HITS-CLIP	19536157
MIRT714293	hsa-miR-6889-3p	HITS-CLIP	19536157
MIRT714292	hsa-miR-5008-3p	HITS-CLIP	19536157
MIRT714291	hsa-miR-6737-3p	HITS-CLIP	19536157
MIRT714290	hsa-miR-7157-3p	HITS-CLIP	19536157
MIRT714289	hsa-miR-3194-5p	HITS-CLIP	19536157
MIRT714288	hsa-miR-1202	HITS-CLIP	19536157
MIRT714287	hsa-miR-3972	HITS-CLIP	19536157
MIRT663887	hsa-miR-4700-3p	HITS-CLIP	23824327
MIRT663888	hsa-miR-138-2-3p	HITS-CLIP	23824327
MIRT663885	hsa-miR-5095	HITS-CLIP	23824327
MIRT663886	hsa-miR-7151-3p	HITS-CLIP	23824327
MIRT714300	hsa-miR-128-3p	HITS-CLIP	19536157
MIRT714299	hsa-miR-216a-3p	HITS-CLIP	19536157
MIRT714298	hsa-miR-3681-3p	HITS-CLIP	19536157
MIRT714297	hsa-miR-6733-3p	HITS-CLIP	19536157
MIRT714296	hsa-miR-4722-3p	HITS-CLIP	19536157
MIRT714295	hsa-miR-6727-3p	HITS-CLIP	19536157
MIRT714294	hsa-miR-6747-3p	HITS-CLIP	19536157
MIRT714293	hsa-miR-6889-3p	HITS-CLIP	19536157
MIRT714292	hsa-miR-5008-3p	HITS-CLIP	19536157
MIRT714291	hsa-miR-6737-3p	HITS-CLIP	19536157
MIRT714290	hsa-miR-7157-3p	HITS-CLIP	19536157
MIRT714289	hsa-miR-3194-5p	HITS-CLIP	19536157
MIRT714288	hsa-miR-1202	HITS-CLIP	19536157
MIRT714287	hsa-miR-3972	HITS-CLIP	19536157
MIRT663887	hsa-miR-4700-3p	HITS-CLIP	23824327
MIRT663888	hsa-miR-138-2-3p	HITS-CLIP	23824327
MIRT663885	hsa-miR-5095	HITS-CLIP	23824327
MIRT663886	hsa-miR-7151-3p	HITS-CLIP	23824327
MIRT1079369	hsa-miR-103a	CLIP-seq
MIRT1079370	hsa-miR-107	CLIP-seq
MIRT1079371	hsa-miR-1184	CLIP-seq
MIRT1079372	hsa-miR-1245b-3p	CLIP-seq
MIRT1079373	hsa-miR-129-5p	CLIP-seq
MIRT1079374	hsa-miR-1305	CLIP-seq
MIRT1079375	hsa-miR-1324	CLIP-seq
MIRT1079376	hsa-miR-146a	CLIP-seq
MIRT1079377	hsa-miR-146b-3p	CLIP-seq
MIRT1079378	hsa-miR-146b-5p	CLIP-seq
MIRT1079379	hsa-miR-219-1-3p	CLIP-seq
MIRT1079380	hsa-miR-22	CLIP-seq
MIRT1079381	hsa-miR-2278	CLIP-seq
MIRT1079382	hsa-miR-298	CLIP-seq
MIRT1079383	hsa-miR-3074-3p	CLIP-seq
MIRT1079384	hsa-miR-3150b-3p	CLIP-seq
MIRT1079385	hsa-miR-3154	CLIP-seq
MIRT1079386	hsa-miR-3155	CLIP-seq
MIRT1079387	hsa-miR-3155b	CLIP-seq
MIRT1079388	hsa-miR-3173-5p	CLIP-seq
MIRT1079389	hsa-miR-3179	CLIP-seq
MIRT1079390	hsa-miR-3198	CLIP-seq
MIRT1079391	hsa-miR-323-3p	CLIP-seq
MIRT1079392	hsa-miR-342-3p	CLIP-seq
MIRT1079393	hsa-miR-361-5p	CLIP-seq
MIRT1079394	hsa-miR-3646	CLIP-seq
MIRT1079395	hsa-miR-365	CLIP-seq
MIRT1079396	hsa-miR-3660	CLIP-seq
MIRT1079397	hsa-miR-3662	CLIP-seq
MIRT1079398	hsa-miR-3674	CLIP-seq
MIRT1079399	hsa-miR-3678-3p	CLIP-seq
MIRT1079400	hsa-miR-3974	CLIP-seq
MIRT1079401	hsa-miR-3978	CLIP-seq
MIRT1079402	hsa-miR-4272	CLIP-seq
MIRT1079403	hsa-miR-4274	CLIP-seq
MIRT1079404	hsa-miR-4283	CLIP-seq
MIRT1079405	hsa-miR-4309	CLIP-seq
MIRT1079406	hsa-miR-4324	CLIP-seq
MIRT1079407	hsa-miR-433	CLIP-seq
MIRT1079408	hsa-miR-4448	CLIP-seq
MIRT1079409	hsa-miR-4468	CLIP-seq
MIRT1079410	hsa-miR-4499	CLIP-seq
MIRT1079411	hsa-miR-4508	CLIP-seq
MIRT1079412	hsa-miR-450b-5p	CLIP-seq
MIRT1079413	hsa-miR-4513	CLIP-seq
MIRT1079414	hsa-miR-4524	CLIP-seq
MIRT1079415	hsa-miR-4526	CLIP-seq
MIRT1079416	hsa-miR-4539	CLIP-seq
MIRT1079417	hsa-miR-4653-3p	CLIP-seq
MIRT1079418	hsa-miR-4662a-5p	CLIP-seq
MIRT1079419	hsa-miR-4672	CLIP-seq
MIRT1079420	hsa-miR-4689	CLIP-seq
MIRT1079421	hsa-miR-4695-3p	CLIP-seq
MIRT1079422	hsa-miR-4698	CLIP-seq
MIRT1079423	hsa-miR-4707-5p	CLIP-seq
MIRT1079424	hsa-miR-4717-3p	CLIP-seq
MIRT1079425	hsa-miR-4775	CLIP-seq
MIRT1079426	hsa-miR-4784	CLIP-seq
MIRT1079427	hsa-miR-4789-5p	CLIP-seq
MIRT1079428	hsa-miR-484	CLIP-seq
MIRT1079429	hsa-miR-505	CLIP-seq
MIRT1079430	hsa-miR-507	CLIP-seq
MIRT1079431	hsa-miR-548p	CLIP-seq
MIRT1079432	hsa-miR-550b	CLIP-seq
MIRT1079433	hsa-miR-557	CLIP-seq
MIRT1079434	hsa-miR-589	CLIP-seq
MIRT1079435	hsa-miR-606	CLIP-seq
MIRT1079436	hsa-miR-626	CLIP-seq
MIRT1079437	hsa-miR-767-5p	CLIP-seq
MIRT1079438	hsa-miR-874	CLIP-seq
MIRT1079439	hsa-miR-95	CLIP-seq
MIRT2019744	hsa-miR-101	CLIP-seq
MIRT2019745	hsa-miR-10a	CLIP-seq
MIRT2019746	hsa-miR-10b	CLIP-seq
MIRT2019747	hsa-miR-1238	CLIP-seq
MIRT2019748	hsa-miR-128	CLIP-seq
MIRT2019749	hsa-miR-1281	CLIP-seq
MIRT2019750	hsa-miR-1307	CLIP-seq
MIRT2019751	hsa-miR-144	CLIP-seq
MIRT2019752	hsa-miR-1976	CLIP-seq
MIRT2019753	hsa-miR-2467-5p	CLIP-seq
MIRT2019754	hsa-miR-3130-3p	CLIP-seq
MIRT2019755	hsa-miR-3145-3p	CLIP-seq
MIRT2019756	hsa-miR-3194-3p	CLIP-seq
MIRT2019757	hsa-miR-340	CLIP-seq
MIRT2019758	hsa-miR-3545-3p	CLIP-seq
MIRT2019759	hsa-miR-3647-3p	CLIP-seq
MIRT2019760	hsa-miR-3664-5p	CLIP-seq
MIRT2019761	hsa-miR-3909	CLIP-seq
MIRT2019762	hsa-miR-3940-5p	CLIP-seq
MIRT2019763	hsa-miR-4252	CLIP-seq
MIRT1079402	hsa-miR-4272	CLIP-seq
MIRT1079404	hsa-miR-4283	CLIP-seq
MIRT2019764	hsa-miR-4286	CLIP-seq
MIRT2019765	hsa-miR-4291	CLIP-seq
MIRT2019766	hsa-miR-4304	CLIP-seq
MIRT2019767	hsa-miR-4320	CLIP-seq
MIRT1079408	hsa-miR-4448	CLIP-seq
MIRT2019768	hsa-miR-4475	CLIP-seq
MIRT2019769	hsa-miR-4506	CLIP-seq
MIRT2019770	hsa-miR-4507	CLIP-seq
MIRT1079411	hsa-miR-4508	CLIP-seq
MIRT2019771	hsa-miR-4520a-5p	CLIP-seq
MIRT2019772	hsa-miR-4520b-5p	CLIP-seq
MIRT2019773	hsa-miR-4638-5p	CLIP-seq
MIRT2019774	hsa-miR-4701-5p	CLIP-seq
MIRT2019775	hsa-miR-4714-5p	CLIP-seq
MIRT2019776	hsa-miR-4742-3p	CLIP-seq
MIRT2019777	hsa-miR-4766-5p	CLIP-seq
MIRT1079425	hsa-miR-4775	CLIP-seq
MIRT1079427	hsa-miR-4789-5p	CLIP-seq
MIRT2019778	hsa-miR-4793-3p	CLIP-seq
MIRT2019779	hsa-miR-502-5p	CLIP-seq
MIRT2019780	hsa-miR-544	CLIP-seq
MIRT2019781	hsa-miR-545	CLIP-seq
MIRT1079431	hsa-miR-548p	CLIP-seq
MIRT2019782	hsa-miR-582-5p	CLIP-seq
MIRT2019783	hsa-miR-588	CLIP-seq
MIRT2019784	hsa-miR-600	CLIP-seq
MIRT2019785	hsa-miR-617	CLIP-seq
MIRT2019786	hsa-miR-633	CLIP-seq
MIRT2019787	hsa-miR-760	CLIP-seq
MIRT2019753	hsa-miR-2467-5p	CLIP-seq
MIRT2251647	hsa-miR-3934	CLIP-seq
MIRT2251648	hsa-miR-421	CLIP-seq
MIRT2251649	hsa-miR-4703-3p	CLIP-seq
MIRT2251650	hsa-miR-4709-5p	CLIP-seq
MIRT1079431	hsa-miR-548p	CLIP-seq
MIRT2251651	hsa-miR-552	CLIP-seq
MIRT2452128	hsa-miR-4282	CLIP-seq
MIRT2019764	hsa-miR-4286	CLIP-seq
MIRT2465501	hsa-miR-181a	CLIP-seq
MIRT2465502	hsa-miR-181b	CLIP-seq
MIRT2465503	hsa-miR-181c	CLIP-seq
MIRT2465504	hsa-miR-181d	CLIP-seq
MIRT1079382	hsa-miR-298	CLIP-seq
MIRT2465505	hsa-miR-3120-3p	CLIP-seq
MIRT2465506	hsa-miR-4262	CLIP-seq
MIRT2465507	hsa-miR-543	CLIP-seq
MIRT2465508	hsa-miR-579	CLIP-seq
MIRT2019784	hsa-miR-600	CLIP-seq
MIRT2465509	hsa-miR-664	CLIP-seq
MIRT2465510	hsa-miR-922	CLIP-seq
MIRT2554951	hsa-miR-1205	CLIP-seq
MIRT1079372	hsa-miR-1245b-3p	CLIP-seq
MIRT2554952	hsa-miR-1283	CLIP-seq
MIRT2554953	hsa-miR-1286	CLIP-seq
MIRT1079381	hsa-miR-2278	CLIP-seq
MIRT2554954	hsa-miR-320a	CLIP-seq
MIRT2554955	hsa-miR-320b	CLIP-seq
MIRT2554956	hsa-miR-320c	CLIP-seq
MIRT2554957	hsa-miR-320d	CLIP-seq
MIRT2554958	hsa-miR-337-5p	CLIP-seq
MIRT2554959	hsa-miR-3616-5p	CLIP-seq
MIRT2554960	hsa-miR-3647-5p	CLIP-seq
MIRT2554961	hsa-miR-4267	CLIP-seq
MIRT1079402	hsa-miR-4272	CLIP-seq
MIRT2554962	hsa-miR-4429	CLIP-seq
MIRT1079409	hsa-miR-4468	CLIP-seq
MIRT2554963	hsa-miR-4519	CLIP-seq
MIRT1079414	hsa-miR-4524	CLIP-seq
MIRT2554964	hsa-miR-4722-5p	CLIP-seq
MIRT2554965	hsa-miR-4724-5p	CLIP-seq
MIRT2554966	hsa-miR-4795-5p	CLIP-seq
MIRT2554967	hsa-miR-520d-5p	CLIP-seq
MIRT2554968	hsa-miR-524-5p	CLIP-seq
MIRT2554969	hsa-miR-573	CLIP-seq
MIRT2554970	hsa-miR-605	CLIP-seq
MIRT1079439	hsa-miR-95	CLIP-seq

MIM	HGNC	e!Ensembl
618794	29104	ENSG00000176595

Protein

UniProt ID

O94819

Protein name

Kelch repeat and BTB domain-containing protein 11 (Chronic myelogenous leukemia-associated protein) (Kelch domain-containing protein 7B)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00651	BTB	138 → 231	BTB/POZ domain	Domain
PF01344	Kelch_1	348 → 399	Kelch motif	Repeat
PF01344	Kelch_1	401 → 442	Kelch motif	Repeat

Sequence

MEHAVAPCVLYPGTEPGAAGESESEGAASPAQTPCSLGASLCFSSGEESPPQSLASAAEG
AATSPPSSGGPRVVERQWEAGSAGAASPEELASPEERACPEEPAAPSPEPRVWLEDPASP
EEPGEPAPVPPGFGAVYGEPDLVLEVSGRRLRAHKAVLAARSDYFRARASRDVLRVQGVS
LTALRLLLADAYSGRMAGVRPDNVAEVVAGARRLQLPGAAQRATDAVGPQLSLANCYEVL
SAAKRQRLNELRDAAYCFMSDHYLEVLREPAVFGRLSGAERDLLLRRRLRAGRAHLLAAA
LGPAGERAGSRPQSPSGDADARGDAAVYCFHAAAGEWRELTRLPEGAPARGCGLCVLYNY
LFVAGGVAPAGPDGRARPSDQVFCYNPATDSWSAVRPLRQARSQLRLLALDGHLYAVGGE
CLLSVERYDPRADRWAPVAPLPRGAFAVAHEATTCHGEIYVSGGSLFYRLLKYDPRRDEW
QECPCSSSRERSADMVALDGFIYRFDLSGSRGEAQAAGPSGVSVSRYHCLAKQWSPCVAP
LRLPGGPTGLQPFRCAALDGAIYCVSRAGTWRFQPAREGEAGGDAGQGGGFEALGAPLDV
RGVLIPFALSLPEKPPRGEQGAP

Sequence length

623

Interactions

View interactions

Show/Hide Unknown Diseases (6)

Disease term	Disease name	Evidence	Source
Unknown
Cervical Cancer	Cervical Cancer	Our screens identified 10 miRNAs that enhance fitness of HeLa cells and have been reported to be up-regulated in cervical cancer (Table2).	GWAS, CBGDA
Multiple Sclerosis	Multiple Sclerosis		GWAS
Mental Depression	Mental Depression		GWAS
Colorectal Cancer	Colorectal Cancer	In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1.	GWAS, CBGDA
Dementia	Dementia		GWAS
Schizophrenia	Schizophrenia		GWAS

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References
Associations from Text Mining
Carcinogenesis	Associate	29267898
Colorectal Neoplasms	Associate	29267898
Neoplasms	Inhibit	29267898

KBTBD11 (kelch repeat and BTB domain containing 11)