Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9901
Gene name Gene Name - the full gene name approved by the HGNC.	SLIT-ROBO Rho GTPase activating protein 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SRGAP3
Synonyms (NCBI Gene) Gene synonyms aliases	ARHGAP14, MEGAP, SRGAP2, WRP
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3p25.3

Show/Hide all(311)

miRTarBase ID	miRNA	Experiments
MIRT1388873	hsa-let-7a	CLIP-seq
MIRT1388874	hsa-let-7b	CLIP-seq
MIRT1388875	hsa-let-7c	CLIP-seq
MIRT1388876	hsa-let-7d	CLIP-seq
MIRT1388877	hsa-let-7e	CLIP-seq
MIRT1388878	hsa-let-7f	CLIP-seq
MIRT1388879	hsa-let-7g	CLIP-seq
MIRT1388880	hsa-let-7i	CLIP-seq
MIRT1388881	hsa-miR-1178	CLIP-seq
MIRT1388882	hsa-miR-1285	CLIP-seq
MIRT1388883	hsa-miR-132	CLIP-seq
MIRT1388884	hsa-miR-144	CLIP-seq
MIRT1388885	hsa-miR-19a	CLIP-seq
MIRT1388886	hsa-miR-19b	CLIP-seq
MIRT1388887	hsa-miR-202	CLIP-seq
MIRT1388888	hsa-miR-203	CLIP-seq
MIRT1388889	hsa-miR-212	CLIP-seq
MIRT1388890	hsa-miR-2861	CLIP-seq
MIRT1388891	hsa-miR-3145-5p	CLIP-seq
MIRT1388892	hsa-miR-3150b-3p	CLIP-seq
MIRT1388893	hsa-miR-3155	CLIP-seq
MIRT1388894	hsa-miR-3155b	CLIP-seq
MIRT1388895	hsa-miR-3187-5p	CLIP-seq
MIRT1388896	hsa-miR-3200-5p	CLIP-seq
MIRT1388897	hsa-miR-326	CLIP-seq
MIRT1388898	hsa-miR-330-5p	CLIP-seq
MIRT1388899	hsa-miR-342-3p	CLIP-seq
MIRT1388900	hsa-miR-3591-5p	CLIP-seq
MIRT1388901	hsa-miR-3616-3p	CLIP-seq
MIRT1388902	hsa-miR-3622b-5p	CLIP-seq
MIRT1388903	hsa-miR-3653	CLIP-seq
MIRT1388904	hsa-miR-3658	CLIP-seq
MIRT1388905	hsa-miR-3660	CLIP-seq
MIRT1388906	hsa-miR-3677-5p	CLIP-seq
MIRT1388907	hsa-miR-3689a-3p	CLIP-seq
MIRT1388908	hsa-miR-3689c	CLIP-seq
MIRT1388909	hsa-miR-377	CLIP-seq
MIRT1388910	hsa-miR-378g	CLIP-seq
MIRT1388911	hsa-miR-411	CLIP-seq
MIRT1388912	hsa-miR-4457	CLIP-seq
MIRT1388913	hsa-miR-4458	CLIP-seq
MIRT1388914	hsa-miR-4460	CLIP-seq
MIRT1388915	hsa-miR-4468	CLIP-seq
MIRT1388916	hsa-miR-4486	CLIP-seq
MIRT1388917	hsa-miR-4500	CLIP-seq
MIRT1388918	hsa-miR-4526	CLIP-seq
MIRT1388919	hsa-miR-4649-3p	CLIP-seq
MIRT1388920	hsa-miR-4663	CLIP-seq
MIRT1388921	hsa-miR-4710	CLIP-seq
MIRT1388922	hsa-miR-4727-3p	CLIP-seq
MIRT1388923	hsa-miR-4728-5p	CLIP-seq
MIRT1388924	hsa-miR-4743	CLIP-seq
MIRT1388925	hsa-miR-4766-5p	CLIP-seq
MIRT1388926	hsa-miR-4773	CLIP-seq
MIRT1388927	hsa-miR-4784	CLIP-seq
MIRT1388928	hsa-miR-4792	CLIP-seq
MIRT1388929	hsa-miR-4802-5p	CLIP-seq
MIRT1388930	hsa-miR-484	CLIP-seq
MIRT1388931	hsa-miR-490-5p	CLIP-seq
MIRT1388932	hsa-miR-518a-5p	CLIP-seq
MIRT1388933	hsa-miR-527	CLIP-seq
MIRT1388934	hsa-miR-549	CLIP-seq
MIRT1388935	hsa-miR-607	CLIP-seq
MIRT1388936	hsa-miR-612	CLIP-seq
MIRT1388937	hsa-miR-642b	CLIP-seq
MIRT1388938	hsa-miR-767-3p	CLIP-seq
MIRT1388939	hsa-miR-885-3p	CLIP-seq
MIRT1388940	hsa-miR-98	CLIP-seq
MIRT1388941	hsa-miR-1262	CLIP-seq
MIRT1388942	hsa-miR-1470	CLIP-seq
MIRT1388943	hsa-miR-199a-5p	CLIP-seq
MIRT1388944	hsa-miR-199b-5p	CLIP-seq
MIRT1388945	hsa-miR-204	CLIP-seq
MIRT1388946	hsa-miR-211	CLIP-seq
MIRT1388947	hsa-miR-24	CLIP-seq
MIRT1388948	hsa-miR-3153	CLIP-seq
MIRT1388949	hsa-miR-3179	CLIP-seq
MIRT1388950	hsa-miR-3180	CLIP-seq
MIRT1388951	hsa-miR-3180-3p	CLIP-seq
MIRT1388952	hsa-miR-3193	CLIP-seq
MIRT1388953	hsa-miR-3196	CLIP-seq
MIRT1388954	hsa-miR-3202	CLIP-seq
MIRT1388900	hsa-miR-3591-5p	CLIP-seq
MIRT1388955	hsa-miR-3614-5p	CLIP-seq
MIRT1388906	hsa-miR-3677-5p	CLIP-seq
MIRT1388956	hsa-miR-3692	CLIP-seq
MIRT1388957	hsa-miR-3922-5p	CLIP-seq
MIRT1388958	hsa-miR-4268	CLIP-seq
MIRT1388959	hsa-miR-4287	CLIP-seq
MIRT1388960	hsa-miR-4330	CLIP-seq
MIRT1388961	hsa-miR-4436b-5p	CLIP-seq
MIRT1388962	hsa-miR-4448	CLIP-seq
MIRT1388963	hsa-miR-4455	CLIP-seq
MIRT1388912	hsa-miR-4457	CLIP-seq
MIRT1388914	hsa-miR-4460	CLIP-seq
MIRT1388964	hsa-miR-4481	CLIP-seq
MIRT1388965	hsa-miR-4488	CLIP-seq
MIRT1388920	hsa-miR-4663	CLIP-seq
MIRT1388966	hsa-miR-4667-3p	CLIP-seq
MIRT1388967	hsa-miR-4676-5p	CLIP-seq
MIRT1388968	hsa-miR-4685-3p	CLIP-seq
MIRT1388969	hsa-miR-4697-5p	CLIP-seq
MIRT1388970	hsa-miR-4699-3p	CLIP-seq
MIRT1388971	hsa-miR-4701-3p	CLIP-seq
MIRT1388972	hsa-miR-4716-3p	CLIP-seq
MIRT1388973	hsa-miR-4723-5p	CLIP-seq
MIRT1388974	hsa-miR-4724-3p	CLIP-seq
MIRT1388922	hsa-miR-4727-3p	CLIP-seq
MIRT1388923	hsa-miR-4728-5p	CLIP-seq
MIRT1388975	hsa-miR-4745-5p	CLIP-seq
MIRT1388976	hsa-miR-4747-5p	CLIP-seq
MIRT1388977	hsa-miR-4762-5p	CLIP-seq
MIRT1388978	hsa-miR-548l	CLIP-seq
MIRT1388979	hsa-miR-575	CLIP-seq
MIRT1388980	hsa-miR-609	CLIP-seq
MIRT1388981	hsa-miR-668	CLIP-seq
MIRT1388938	hsa-miR-767-3p	CLIP-seq
MIRT1388939	hsa-miR-885-3p	CLIP-seq
MIRT1557124	hsa-miR-4446-5p	CLIP-seq
MIRT1557125	hsa-miR-4742-3p	CLIP-seq
MIRT2116579	hsa-miR-1245	CLIP-seq
MIRT2116580	hsa-miR-1266	CLIP-seq
MIRT2116581	hsa-miR-1299	CLIP-seq
MIRT2116582	hsa-miR-150	CLIP-seq
MIRT2116583	hsa-miR-192	CLIP-seq
MIRT2116584	hsa-miR-215	CLIP-seq
MIRT2116585	hsa-miR-329	CLIP-seq
MIRT2116586	hsa-miR-362-3p	CLIP-seq
MIRT2116587	hsa-miR-3662	CLIP-seq
MIRT2116588	hsa-miR-3664-3p	CLIP-seq
MIRT2116589	hsa-miR-4310	CLIP-seq
MIRT2116590	hsa-miR-4432	CLIP-seq
MIRT2116591	hsa-miR-4433	CLIP-seq
MIRT2116592	hsa-miR-4459	CLIP-seq
MIRT2116593	hsa-miR-4492	CLIP-seq
MIRT2116594	hsa-miR-4498	CLIP-seq
MIRT2116595	hsa-miR-4505	CLIP-seq
MIRT2116596	hsa-miR-4518	CLIP-seq
MIRT2116597	hsa-miR-4713-5p	CLIP-seq
MIRT1388974	hsa-miR-4724-3p	CLIP-seq
MIRT1388923	hsa-miR-4728-5p	CLIP-seq
MIRT2116598	hsa-miR-4768-3p	CLIP-seq
MIRT2116599	hsa-miR-4782-5p	CLIP-seq
MIRT2116600	hsa-miR-499-5p	CLIP-seq
MIRT2116601	hsa-miR-516b	CLIP-seq
MIRT2116602	hsa-miR-519a	CLIP-seq
MIRT2116603	hsa-miR-519b-3p	CLIP-seq
MIRT2116604	hsa-miR-519c-3p	CLIP-seq
MIRT2116605	hsa-miR-532-3p	CLIP-seq
MIRT2116606	hsa-miR-570	CLIP-seq
MIRT2116607	hsa-miR-760	CLIP-seq
MIRT2116608	hsa-miR-762	CLIP-seq
MIRT2116609	hsa-miR-940	CLIP-seq
MIRT2116579	hsa-miR-1245	CLIP-seq
MIRT2116580	hsa-miR-1266	CLIP-seq
MIRT2338924	hsa-miR-1287	CLIP-seq
MIRT2338925	hsa-miR-1298	CLIP-seq
MIRT2116581	hsa-miR-1299	CLIP-seq
MIRT1388883	hsa-miR-132	CLIP-seq
MIRT2338926	hsa-miR-138	CLIP-seq
MIRT2338927	hsa-miR-151-3p	CLIP-seq
MIRT2338928	hsa-miR-1827	CLIP-seq
MIRT2338929	hsa-miR-1913	CLIP-seq
MIRT2116583	hsa-miR-192	CLIP-seq
MIRT1388943	hsa-miR-199a-5p	CLIP-seq
MIRT1388944	hsa-miR-199b-5p	CLIP-seq
MIRT1388889	hsa-miR-212	CLIP-seq
MIRT2116584	hsa-miR-215	CLIP-seq
MIRT2338930	hsa-miR-23a	CLIP-seq
MIRT2338931	hsa-miR-23b	CLIP-seq
MIRT2338932	hsa-miR-23c	CLIP-seq
MIRT2338933	hsa-miR-30a	CLIP-seq
MIRT2338934	hsa-miR-30b	CLIP-seq
MIRT2338935	hsa-miR-30c	CLIP-seq
MIRT2338936	hsa-miR-30d	CLIP-seq
MIRT2338937	hsa-miR-30e	CLIP-seq
MIRT2338938	hsa-miR-3120-3p	CLIP-seq
MIRT1388891	hsa-miR-3145-5p	CLIP-seq
MIRT2338939	hsa-miR-3175	CLIP-seq
MIRT2338940	hsa-miR-3180-5p	CLIP-seq
MIRT1388954	hsa-miR-3202	CLIP-seq
MIRT2338941	hsa-miR-324-3p	CLIP-seq
MIRT1388897	hsa-miR-326	CLIP-seq
MIRT1388898	hsa-miR-330-5p	CLIP-seq
MIRT2338942	hsa-miR-338-3p	CLIP-seq
MIRT2116588	hsa-miR-3664-3p	CLIP-seq
MIRT2338943	hsa-miR-3668	CLIP-seq
MIRT1388906	hsa-miR-3677-5p	CLIP-seq
MIRT2338944	hsa-miR-383	CLIP-seq
MIRT2338945	hsa-miR-384	CLIP-seq
MIRT1388957	hsa-miR-3922-5p	CLIP-seq
MIRT2338946	hsa-miR-3942-5p	CLIP-seq
MIRT1388958	hsa-miR-4268	CLIP-seq
MIRT2338947	hsa-miR-4290	CLIP-seq
MIRT2116589	hsa-miR-4310	CLIP-seq
MIRT2338948	hsa-miR-4316	CLIP-seq
MIRT2338949	hsa-miR-4325	CLIP-seq
MIRT2116590	hsa-miR-4432	CLIP-seq
MIRT2116591	hsa-miR-4433	CLIP-seq
MIRT1388962	hsa-miR-4448	CLIP-seq
MIRT2116592	hsa-miR-4459	CLIP-seq
MIRT2338950	hsa-miR-4463	CLIP-seq
MIRT1388964	hsa-miR-4481	CLIP-seq
MIRT2338951	hsa-miR-4493	CLIP-seq
MIRT2338952	hsa-miR-4494	CLIP-seq
MIRT2338953	hsa-miR-4495	CLIP-seq
MIRT2338954	hsa-miR-4499	CLIP-seq
MIRT2338955	hsa-miR-4503	CLIP-seq
MIRT2116596	hsa-miR-4518	CLIP-seq
MIRT2338956	hsa-miR-4522	CLIP-seq
MIRT2338957	hsa-miR-4530	CLIP-seq
MIRT2338958	hsa-miR-4533	CLIP-seq
MIRT2338959	hsa-miR-4666-5p	CLIP-seq
MIRT1388967	hsa-miR-4676-5p	CLIP-seq
MIRT2338960	hsa-miR-4690-3p	CLIP-seq
MIRT2338961	hsa-miR-4693-3p	CLIP-seq
MIRT2338962	hsa-miR-4703-5p	CLIP-seq
MIRT2338963	hsa-miR-4704-3p	CLIP-seq
MIRT2338964	hsa-miR-4717-5p	CLIP-seq
MIRT2338965	hsa-miR-4732-5p	CLIP-seq
MIRT2338966	hsa-miR-4736	CLIP-seq
MIRT1388975	hsa-miR-4745-5p	CLIP-seq
MIRT2338967	hsa-miR-4753-5p	CLIP-seq
MIRT2116598	hsa-miR-4768-3p	CLIP-seq
MIRT2338968	hsa-miR-4771	CLIP-seq
MIRT2338969	hsa-miR-4772-5p	CLIP-seq
MIRT2116599	hsa-miR-4782-5p	CLIP-seq
MIRT2116600	hsa-miR-499-5p	CLIP-seq
MIRT2338970	hsa-miR-501-3p	CLIP-seq
MIRT2338971	hsa-miR-502-3p	CLIP-seq
MIRT2338972	hsa-miR-507	CLIP-seq
MIRT2116601	hsa-miR-516b	CLIP-seq
MIRT1388934	hsa-miR-549	CLIP-seq
MIRT2338973	hsa-miR-557	CLIP-seq
MIRT2116606	hsa-miR-570	CLIP-seq
MIRT1388979	hsa-miR-575	CLIP-seq
MIRT2338974	hsa-miR-635	CLIP-seq
MIRT2338975	hsa-miR-648	CLIP-seq
MIRT1388938	hsa-miR-767-3p	CLIP-seq
MIRT2338976	hsa-miR-875-3p	CLIP-seq
MIRT2338977	hsa-miR-935	CLIP-seq
MIRT2460543	hsa-miR-3190	CLIP-seq
MIRT2460544	hsa-miR-3911	CLIP-seq
MIRT2338949	hsa-miR-4325	CLIP-seq
MIRT2338972	hsa-miR-507	CLIP-seq
MIRT2338973	hsa-miR-557	CLIP-seq
MIRT2338975	hsa-miR-648	CLIP-seq
MIRT2632524	hsa-miR-1245b-3p	CLIP-seq
MIRT2632525	hsa-miR-1292	CLIP-seq
MIRT2632526	hsa-miR-153	CLIP-seq
MIRT2632527	hsa-miR-3065-5p	CLIP-seq
MIRT2632528	hsa-miR-3173-3p	CLIP-seq
MIRT1388950	hsa-miR-3180	CLIP-seq
MIRT1388951	hsa-miR-3180-3p	CLIP-seq
MIRT2632529	hsa-miR-3187-3p	CLIP-seq
MIRT1388953	hsa-miR-3196	CLIP-seq
MIRT2632530	hsa-miR-3689d	CLIP-seq
MIRT2632531	hsa-miR-371-3p	CLIP-seq
MIRT2632532	hsa-miR-371b-3p	CLIP-seq
MIRT1388909	hsa-miR-377	CLIP-seq
MIRT2632533	hsa-miR-3915	CLIP-seq
MIRT2632534	hsa-miR-3928	CLIP-seq
MIRT2632535	hsa-miR-4276	CLIP-seq
MIRT2632536	hsa-miR-4311	CLIP-seq
MIRT2116591	hsa-miR-4433	CLIP-seq
MIRT2632537	hsa-miR-4471	CLIP-seq
MIRT1388965	hsa-miR-4488	CLIP-seq
MIRT2632538	hsa-miR-4514	CLIP-seq
MIRT2632539	hsa-miR-4529-5p	CLIP-seq
MIRT2632540	hsa-miR-4688	CLIP-seq
MIRT2632541	hsa-miR-4692	CLIP-seq
MIRT1388969	hsa-miR-4697-5p	CLIP-seq
MIRT2632542	hsa-miR-4722-5p	CLIP-seq
MIRT1388923	hsa-miR-4728-5p	CLIP-seq
MIRT2632543	hsa-miR-4795-5p	CLIP-seq
MIRT2632544	hsa-miR-486-3p	CLIP-seq
MIRT2632545	hsa-miR-505	CLIP-seq
MIRT2632546	hsa-miR-515-3p	CLIP-seq
MIRT2632547	hsa-miR-519e	CLIP-seq
MIRT1388939	hsa-miR-885-3p	CLIP-seq
MIRT2116609	hsa-miR-940	CLIP-seq
MIRT2632524	hsa-miR-1245b-3p	CLIP-seq
MIRT2691959	hsa-miR-1252	CLIP-seq
MIRT2632525	hsa-miR-1292	CLIP-seq
MIRT2632526	hsa-miR-153	CLIP-seq
MIRT2691960	hsa-miR-2110	CLIP-seq
MIRT2632527	hsa-miR-3065-5p	CLIP-seq
MIRT2691961	hsa-miR-3121-3p	CLIP-seq
MIRT2691962	hsa-miR-3150a-3p	CLIP-seq
MIRT2632528	hsa-miR-3173-3p	CLIP-seq
MIRT2338939	hsa-miR-3175	CLIP-seq
MIRT2632530	hsa-miR-3689d	CLIP-seq
MIRT2632531	hsa-miR-371-3p	CLIP-seq
MIRT2632532	hsa-miR-371b-3p	CLIP-seq
MIRT1388909	hsa-miR-377	CLIP-seq
MIRT2632533	hsa-miR-3915	CLIP-seq
MIRT2632534	hsa-miR-3928	CLIP-seq
MIRT2691963	hsa-miR-4260	CLIP-seq
MIRT2691964	hsa-miR-4261	CLIP-seq
MIRT2632537	hsa-miR-4471	CLIP-seq
MIRT2691965	hsa-miR-4476	CLIP-seq
MIRT2691966	hsa-miR-4496	CLIP-seq
MIRT2338958	hsa-miR-4533	CLIP-seq
MIRT2632540	hsa-miR-4688	CLIP-seq
MIRT2691967	hsa-miR-4691-3p	CLIP-seq
MIRT2632543	hsa-miR-4795-5p	CLIP-seq
MIRT2632544	hsa-miR-486-3p	CLIP-seq
MIRT2632545	hsa-miR-505	CLIP-seq
MIRT2632546	hsa-miR-515-3p	CLIP-seq
MIRT2632547	hsa-miR-519e	CLIP-seq
MIRT2691968	hsa-miR-939	CLIP-seq

Show/Hide all(13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005096	Function	GTPase activator activity	IBA
GO:0005096	Function	GTPase activator activity	IEA
GO:0005096	Function	GTPase activator activity	TAS
GO:0005515	Function	Protein binding	IPI	17500595, 25819436
GO:0005829	Component	Cytosol	TAS
GO:0007165	Process	Signal transduction	IEA
GO:0007399	Process	Nervous system development	IBA
GO:0030336	Process	Negative regulation of cell migration	IBA
GO:0045202	Component	Synapse	IEA
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	TAS
GO:0051963	Process	Regulation of synapse assembly	IBA
GO:0098794	Component	Postsynapse	IDA	30123108
GO:0098794	Component	Postsynapse	IMP	30123108

MIM	HGNC	e!Ensembl
606525	19744	ENSG00000196220

Protein

UniProt ID

O43295

Protein name

SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (Mental disorder-associated GAP) (Rho GTPase-activating protein 14) (WAVE-associated Rac GTPase-activating protein) (WRP)

Protein function

GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00611	FCH	31 → 115	Fes/CIP4, and EFC/F-BAR homology domain	Family
PF00620	RhoGAP	520 → 672	RhoGAP domain	Domain
PF00018	SH3_1	750 → 795	SH3 domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in adult and fetal brain. Expressed at low levels in kidney. Isoform 3 is expressed in the kidney but is absent in the brain. {ECO:0000269|PubMed:12195014, ECO:0000269|PubMed:12447388}.

Sequence

MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIE
LEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIF
MNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESK
LKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKAR
NDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLD
VIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYH
QLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYM
SKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTTRP
PCLPPKPQKMRRPRPLSVYSHKLFNGSMEAFIKDSGQAIPLVVESCIRYINLYGLQQQGI
FRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDL
ISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFG
PTLMHIPDGQDPVSCQAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPH
SEPGAIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLYHRASED
WWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTE
HISDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIP
LTRGRIESPEKRRMATFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEAL
AEDIEKTMSTALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPVSSEPASPLHTIVIRD
PDAAMRRSSSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPA
VTPTEKMFPNSSADKSGTM

Sequence length

1099

Interactions

View interactions

	KEGG		Reactome
	Axon guidance		Rho GTPase cycle

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Astrocytoma	Pilocytic astrocytoma	N/A	N/A	GWAS
Breast Cancer	Breast cancer	N/A	N/A	GWAS
Metabolic Syndrome	Metabolic syndrome	N/A	N/A	GWAS

Show/Hide Text Mining Associations (10)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	30151992
Asthma	Associate	35205259
Carcinoma Hepatocellular	Associate	35913371
Cognition Disorders	Associate	23040932
Hemangioma	Associate	40416971
Inflammation	Associate	35205259
Intellectual Disability	Associate	23040932
Parkinson Disease	Associate	20035503
Rumination Syndrome	Associate	30886212
Status Asthmaticus	Associate	35205259

SRGAP3 (SLIT-ROBO Rho GTPase activating protein 3)