Gene Gene information from NCBI Gene database.
Entrez ID 9889
Gene name Zinc finger BED-type containing 4
Gene symbol ZBED4
Synonyms (NCBI Gene)
-
Chromosome 22
Chromosome location 22q13.33
miRNA miRNA information provided by mirtarbase database.
414
miRTarBase ID miRNA Experiments Reference
MIRT016619 hsa-miR-484 Sequencing 20371350
MIRT027812 hsa-miR-98-5p Microarray 19088304
MIRT439261 ebv-miR-BART4-5p HITS-CLIP 22473208
MIRT439261 ebv-miR-BART4-5p HITS-CLIP 22473208
MIRT1501754 hsa-miR-1 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
24
GO ID Ontology Definition Evidence Reference
GO:0000785 Component Chromatin ISA
GO:0000976 Function Transcription cis-regulatory region binding IEA
GO:0000976 Function Transcription cis-regulatory region binding ISS
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding ISS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612552 20721 ENSG00000100426
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O75132
Protein name Zinc finger BED domain-containing protein 4
Protein function Transcriptional regulator that binds to poly-guanine tracts in gene promoters and activates transcription (By similarity). Able to bind single- and double-stranded DNA and RNA (By similarity).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02892 zf-BED 118 166 BED zinc finger Domain
PF02892 zf-BED 288 336 BED zinc finger Domain
PF02892 zf-BED 459 506 BED zinc finger Domain
PF02892 zf-BED 561 609 BED zinc finger Domain
PF05699 Dimer_Tnp_hAT 1086 1164 hAT family C-terminal dimerisation region Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in testis, heart, lung, and weakly expressed in brain, liver, muscle, placenta and small intestine (PubMed:19369242). Expressed in the retina, found in the cone photoreceptors, Mueller cells, cone pedicles and in the innermos
Sequence
MENNLKTCPKEDGDFVSDKIKFKIEEEDDDGIPPDSLERMDFKSEQEDMKQTDSGGERAG
LGGTGCSCKPPGKYLSAESEDDYGALFSQYSSTLYDVAMEAVTQSLLSSRNMSSRKKSPA
WKHFFISPRDSTKAICMYCVKEFSRGKNEKDLSTSCLMRHVRRAHP
TVLIQENGSVSAVS
SFPSPSLLLPPQPADAGDLSTILSPIKLVQKVASKIPSPDRITEESVSVVSSEEISSDMS
VSEKCGREEALVGSSPHLPALHYDEPAENLAEKSLPLPKSTSGSRRRSAVWKHFYLSPLD
NSKAVCIHCMNEFSRGKNGKDLGTSCLIRHMWRAHR
AIVLQENGGTGIPPLYSTPPTLLP
SLLPPEGELSSVSSSPVKPVRESPSASSSPDRLTEDLQSHLNPGDGLMEDVAAFSSSDDI
GEASASSPEKQQADGLSPRLFESGAIFQQNKKVMKRLKSEVWHHFSLAPMDSLKAECRYC
GCAISRGKKGDVGTSCLMRHLYRRHP
EVVGSQKGFLGASLANSPYATLASAESSSSKLTD
LPTVVTKNNQVMFPVNSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCL
LRHLQRFHS
NVLKTEVSETARPSSPDTRVPRGTELSGASSFDDTNEKFYDSHPVAKKITS
LIAEMIALDLQPYSFVDNVGFNRLLEYLKPQYSLPAPSYFSRTAIPGMYDNVKQIIMSHL
KEAESGVIHFTSGIWMSNQTREYLTLTAHWVSFESPARPRCDDHHCSALLDVSQVDCDYS
GNSIQKQLECWWEAWVTSTGLQVGITVTDNASIGKTLNEGEHSSVQCFSHTVNLIVSEAI
KSQRMVQNLLSLARKICERVHRSPKAKEKLAELQREYALPQHHLIQDVPSKWSTSFHMLE
RLIEQKRAINEMSVECNFRELISCDQWEVMQSVCRALKPFEAASREMSTQMSTLSQVIPM
VHILNRKVEMLFEETMGIDTMLRSLKEAMVSRLSATLHDPRYVFATLLDPRYKASLFTEE
EAEQYKQDLIRELELMNSTSEDVAASHRCDAGSPSKDSAAEENLWSLVAKVKKKDPREKL
PEAMVLAYLEEEVLEHSCDPLTYWNLKKASWPGLSALAVRFLGCPPSIVPSEKLFNTPTE
NGSLGQSRLMMEHFEKLIFLKVNL
PLIYFQY
Sequence length 1171
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
2
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Short stature Pathogenic rs1333906033 RCV000736165
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Familial cancer of breast Uncertain significance rs200372064 RCV005932643