TESPA1 (thymocyte expressed, positive selection associated 1)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9840
Gene name Gene Name - the full gene name approved by the HGNC.
Thymocyte expressed, positive selection associated 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TESPA1
Synonyms (NCBI Gene) Gene synonyms aliases
HSPC257, ITPRID3, KIAA0748
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q13.2
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(21)
miRTarBase ID miRNA Experiments Reference
MIRT017883 hsa-miR-335-5p Microarray 18185580
MIRT642980 hsa-miR-551b-5p HITS-CLIP 23824327
MIRT642979 hsa-miR-29a-3p HITS-CLIP 23824327
MIRT642978 hsa-miR-29b-3p HITS-CLIP 23824327
MIRT642977 hsa-miR-29c-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(9)
GO ID Ontology Definition Evidence Reference
GO:0005102 Function Signaling receptor binding IEA
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005737 Component Cytoplasm ISS
GO:0005789 Component Endoplasmic reticulum membrane IEA
GO:0008180 Component COP9 signalosome IDA 22561606
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
615664 29109 ENSG00000135426
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID A2RU30
Protein name Protein TESPA1 (Thymocyte-expressed positive selection-associated protein 1)
Protein function Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity). Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pa
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14722 KRAP_IP3R_bind 128 → 291 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Family
Sequence 
MEASVLSPTSWEKRRAWLRQSRNWQTQVLEEEAAAALQDVPDPEPSSLDDVFQEGNPINK
IEDWLQDCGYSEEGFSEEAGQFIYNGFCSHGTSFEDDLTLGAEATLLAANGKLFSRSFLE
TARPCQLLDLGCSLASSSMTGGTNKTSSSISEILDKVQEDAEDVLFSLGFGQEDHKDTSR
IPARFFTTPSQAKGIDFQLFLKSQVRRIEMEDPCLMLASRFKQVQTLAVTADAFFCLYSY
VSKTPVQKFTPSHMFWNCNHPTDVPSIRILSREPEPQSPRDRLRKAISKMCLYTCPRDRP
PPPHNTPKRNSLDQVVLEVMDKVKEEKQFLQQDSDLGQFSQEDPVPPAEGKKLPTSPYPC
VFCCEEETQQRMSTVLAPSQTLDSNPKVPCCTHSLPIEDPQWSTDPAQIRRELCSLPATN
TETHPAKDETFWKRKSRARKSLFQKNLMGRKVKSLDLSITQQKWKQSVDRPELRRSLSQQ
PQDTFDLEEVQSNSEEEQSQSRWPSRPRHPHHHQTFAGKDS
Sequence length 521
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (3)
Unknown
Disease term Disease name Evidence References Source
Asthma Asthma, Childhood asthma 30929738, 31036433 ClinVar, GWAS
Eczema Eczema GWAS
Dermatitis Dermatitis GWAS
Show/Hide Text Mining Associations (4)
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 33280515
Carcinoma Squamous Cell Associate 28099906
Inflammatory Bowel Diseases Associate 36029471
Pancreatic Neoplasms Associate 28099906