Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9839
Gene name Gene Name - the full gene name approved by the HGNC.	Zinc finger E-box binding homeobox 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ZEB2
Synonyms (NCBI Gene) Gene synonyms aliases	HSPC082, SIP-1, SIP1, SMADIP1, ZFHX1B
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2q22.3
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene

Show/Hide all(173)

SNP ID	Visualize variation	Clinical significance	Consequence
rs6711223	G>A,T	Likely-benign, pathogenic, benign	Genic downstream transcript variant, coding sequence variant, stop gained, synonymous variant
rs111724246	G>C,T	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs137852980	T>A,G	Pathogenic	Synonymous variant, stop gained, coding sequence variant, genic downstream transcript variant
rs137852981	G>A	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs137852982	G>A,C	Pathogenic	Missense variant, stop gained, coding sequence variant, genic downstream transcript variant
rs137852983	T>C	Pathogenic	Missense variant, coding sequence variant, genic downstream transcript variant
rs139944383	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic downstream transcript variant, coding sequence variant, synonymous variant
rs141674976	C>A,T	Benign, conflicting-interpretations-of-pathogenicity, uncertain-significance, likely-benign	Genic downstream transcript variant, coding sequence variant, synonymous variant
rs146394306	G>C	Likely-benign, conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant, non coding transcript variant
rs147693839	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Missense variant, coding sequence variant, genic downstream transcript variant
rs149882004	C>G,T	Likely-benign, conflicting-interpretations-of-pathogenicity, benign, uncertain-significance	Missense variant, coding sequence variant, synonymous variant, non coding transcript variant
rs185223937	T>A,C	Benign, likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, synonymous variant, coding sequence variant
rs199951665	T>C	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Coding sequence variant, genic downstream transcript variant, missense variant
rs201109457	T>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic downstream transcript variant, missense variant
rs397515448	A>G	Pathogenic	Coding sequence variant, missense variant, genic downstream transcript variant
rs397515449	T>C	Pathogenic	Coding sequence variant, missense variant, genic downstream transcript variant
rs398124274	G>A	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs398124275	->G	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs398124276	G>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs398124277	A>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs398124278	->GAGT	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs398124280	AGTACC>CATTA	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs398124281	TAGCCCCGGTCGCAGTA>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs398124282	A>G	Pathogenic, likely-pathogenic	Splice donor variant
rs398124283	AC>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs398124284	G>A	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs587776603	GTTT>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs587776604	->T	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs587776605	TG>-,TGTG	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs587776606	->A	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs587776607	T>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs587776608	->CA	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs587776609	->GG	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs587776610	TGT>-	Pathogenic, uncertain-significance	Inframe deletion, genic downstream transcript variant, coding sequence variant
rs587776611	A>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs587776612	C>T	Pathogenic	Splice acceptor variant
rs587784563	G>A,T	Pathogenic	Stop gained, genic downstream transcript variant, coding sequence variant, synonymous variant
rs587784565	T>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs587784566	G>A	Pathogenic	Stop gained, genic downstream transcript variant, coding sequence variant
rs587784568	TGGCGTGCCAAGGCGAGAC>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs587784570	G>A,C	Pathogenic	Stop gained, genic downstream transcript variant, coding sequence variant, missense variant
rs587784571	G>A	Pathogenic	Stop gained, genic downstream transcript variant, coding sequence variant
rs727503784	A>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs727504223	G>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs727504224	C>A,T	Pathogenic, uncertain-significance	Stop gained, genic downstream transcript variant, coding sequence variant, missense variant
rs727504226	T>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs727504228	C>A	Pathogenic	Stop gained, genic downstream transcript variant, coding sequence variant
rs730881186	G>A	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic downstream transcript variant, intron variant
rs730881208	T>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs730881209	A>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs730881211	GA>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs730881212	C>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs730881213	->T	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs730881215	TAGCTGGACTCGT>AAC	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs730881217	T>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs730881218	T>-	Pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant
rs756686919	G>A,C,T	Pathogenic	Stop gained, genic downstream transcript variant, coding sequence variant, missense variant
rs778851716	G>A	Conflicting-interpretations-of-pathogenicity	Synonymous variant, coding sequence variant, genic downstream transcript variant
rs786200997	->T	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786203990	->A	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786203991	C>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786203992	A>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786203993	C>A	Pathogenic	Splice acceptor variant, genic downstream transcript variant
rs786204801	C>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786204802	->A	Pathogenic	Frameshift variant, coding sequence variant, non coding transcript variant
rs786204803	G>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786204804	->GT	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786204805	TGGTTCTGTTT>CATTAATTTTAAGTCA	Pathogenic	Coding sequence variant, inframe indel, stop gained, genic downstream transcript variant
rs786204806	C>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786204807	A>C	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs786204808	G>T	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs786204809	A>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786204810	AA>-,A	Likely-pathogenic, pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786204811	A>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786204812	AGAGCTT>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786204813	C>-	Pathogenic	Coding sequence variant, non coding transcript variant, splice donor variant
rs786204814	CCTGG>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786204815	G>A	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs786204816	CCCTCGGCAT>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786204817	C>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786204818	AT>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786204819	T>-	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs786204820	G>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs786204821	AAGA>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs794727924	G>A,C	Pathogenic	Coding sequence variant, stop gained, missense variant, genic downstream transcript variant
rs797046117	A>T	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs797046118	A>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs797046119	AGTG>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs797046120	A>T	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs797046121	G>T	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs797046122	G>T	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs863224942	C>A	Likely-pathogenic	Coding sequence variant, missense variant, genic downstream transcript variant
rs878853016	T>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs878855329	GGTTTGG>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs886039655	G>-	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs886041338	G>A	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs886041489	G>-	Pathogenic	Coding sequence variant, genic downstream transcript variant, frameshift variant, intron variant
rs886041601	->TG	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs886041698	G>T	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs886041989	G>A	Pathogenic-likely-pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs886044396	A>T	Likely-pathogenic	Coding sequence variant, genic downstream transcript variant, missense variant
rs1057518156	G>C	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs1057518185	G>A	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs1057518193	TCAT>-	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1060499770	ACCCTCC>-	Likely-pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1060500653	C>-	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1114167349	T>G	Pathogenic	Missense variant, coding sequence variant, genic downstream transcript variant
rs1131691309	->A	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant, intron variant
rs1131691714	C>T	Pathogenic	Splice donor variant, genic downstream transcript variant
rs1131691756	T>-	Pathogenic	Coding sequence variant, frameshift variant, non coding transcript variant
rs1131691912	->T	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1135401790	C>T	Pathogenic	Missense variant, coding sequence variant, genic downstream transcript variant
rs1135402759	T>C	Likely-pathogenic	Missense variant, coding sequence variant, genic downstream transcript variant
rs1423851170	G>T	Likely-pathogenic	Genic downstream transcript variant, coding sequence variant, stop gained
rs1553960776	->C	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553960778	G>T	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs1553960788	G>A	Likely-pathogenic	Missense variant, coding sequence variant, genic downstream transcript variant
rs1553960793	T>A	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs1553961332	A>C	Likely-pathogenic	Missense variant, coding sequence variant, genic downstream transcript variant
rs1553961343	CT>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553961487	C>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553961510	->T	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553961516	G>T	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs1553961580	A>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553961585	->GGAG	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553961598	->TGGGAGCTAACGGCTTGGAGCTTCTTTCCAGGGATGGGGACCTGGAATTTGAGTACTGGTAGACTTTTCGTTGTTCAAACCATTCCTTCACAAATTCCTGAGGAAGGCCCACAGC	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant, inframe indel
rs1553961610	C>T	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs1553961655	C>A	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs1553961660	G>C	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs1553961695	->T	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553961697	G>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553961702	G>A	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs1553961705	A>T	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs1553961746	GTTTT>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553961747	T>-	Likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553961749	->AAGT	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant, inframe indel
rs1553961777	T>A	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs1553962048	GT>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553962069	C>A,T	Uncertain-significance, pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant, missense variant
rs1553962198	C>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553964145	->C	Likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553964147	CA>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553971826	->T	Pathogenic	Non coding transcript variant, frameshift variant, coding sequence variant
rs1560602156	G>T	Pathogenic	Coding sequence variant, genic downstream transcript variant, stop gained
rs1560602214	A>G	Likely-pathogenic	Coding sequence variant, genic downstream transcript variant, missense variant
rs1560604977	G>A	Pathogenic	Coding sequence variant, genic downstream transcript variant, stop gained
rs1560605892	C>-	Pathogenic	Coding sequence variant, genic downstream transcript variant, frameshift variant
rs1560606294	C>-	Pathogenic	Coding sequence variant, genic downstream transcript variant, frameshift variant
rs1560606974	->T	Pathogenic	Coding sequence variant, genic downstream transcript variant, frameshift variant
rs1560607925	T>C	Pathogenic	Splice acceptor variant, genic downstream transcript variant
rs1560609721	G>A	Pathogenic	Coding sequence variant, genic downstream transcript variant, stop gained
rs1560609810	->A	Pathogenic	Coding sequence variant, genic downstream transcript variant, stop gained
rs1560618505	A>T	Pathogenic	Coding sequence variant, genic downstream transcript variant, intron variant, stop gained
rs1560620837	GGCA>-	Pathogenic	Coding sequence variant, genic downstream transcript variant, stop gained
rs1573708153	T>C	Likely-pathogenic	Coding sequence variant, missense variant, genic downstream transcript variant
rs1573708180	T>-	Likely-pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1573713430	C>T	Likely-pathogenic	Coding sequence variant, missense variant, genic downstream transcript variant
rs1573713477	ATACATGC>-	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs1573715510	->AG	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1573716158	G>A	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs1573716795	G>C	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs1573717173	C>-	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1573717593	GAAGAA>TTCTT	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1573717685	A>-	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1573718595	T>C	Likely-pathogenic	Coding sequence variant, missense variant, genic downstream transcript variant
rs1573718600	TC>AT	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs1573718630	CT>-	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1573721065	TC>-	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1573721242	C>-	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1573722122	T>-	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1573722407	CTGAT>-	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1573743888	G>-	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1573743951	AC>-	Pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant

Show/Hide all(384)

miRTarBase ID	miRNA	Experiments	Reference
MIRT000316	hsa-miR-141-3p	qRT-PCR	18925646
MIRT000316	hsa-miR-141-3p	qRT-PCR	18925646
MIRT001036	hsa-miR-200c-3p	qRT-PCR	18925646
MIRT001036	hsa-miR-200c-3p	qRT-PCR	18925646
MIRT001035	hsa-miR-200a-3p	qRT-PCR, Western blot	19703993
MIRT001036	hsa-miR-200c-3p	qRT-PCR, Luciferase reporter assay, Western blot	18381893
MIRT001035	hsa-miR-200a-3p	qRT-PCR, Luciferase reporter assay, Western blot	18381893
MIRT001035	hsa-miR-200a-3p	Review	19574400
MIRT001035	hsa-miR-200a-3p	Review	19574400
MIRT001036	hsa-miR-200c-3p	Review	19574400
MIRT001036	hsa-miR-200c-3p	Review	19574400
MIRT000723	hsa-miR-200b-3p	Review	19574400
MIRT000723	hsa-miR-200b-3p	Review	19574400
MIRT000316	hsa-miR-141-3p	Luciferase reporter assay	19854497
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay	18829540
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay	19854497
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay	18829540
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay	19839049
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay	19854497
MIRT001036	hsa-miR-200c-3p	Luciferase reporter assay	19839049
MIRT001036	hsa-miR-200c-3p	Luciferase reporter assay	19854497
MIRT000048	hsa-miR-429	Luciferase reporter assay	18829540
MIRT000048	hsa-miR-429	Luciferase reporter assay	19854497
MIRT003666	hsa-miR-205-5p	immunoblot, qRT-PCR	19244118
MIRT003666	hsa-miR-205-5p	immunoblot, qRT-PCR	19244118
MIRT001035	hsa-miR-200a-3p	qRT-PCR	19854497
MIRT000723	hsa-miR-200b-3p	qRT-PCR	19854497
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay	19854497
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay	19854497
MIRT000048	hsa-miR-429	intrarenal expression	19910931
MIRT001035	hsa-miR-200a-3p	intrarenal expression	19910931
MIRT000723	hsa-miR-200b-3p	intrarenal expression	19910931
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	19931509
MIRT000048	hsa-miR-429	Review	20130964
MIRT003666	hsa-miR-205-5p	Review	20026422
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR	19854497
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay, qRT-PCR	19854497
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR	18411277
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay, qRT-PCR	18411277
MIRT000048	hsa-miR-429	Luciferase reporter assay, qRT-PCR	18411277
MIRT000316	hsa-miR-141-3p	Luciferase reporter assay, qRT-PCR	18411277
MIRT001036	hsa-miR-200c-3p	Luciferase reporter assay, qRT-PCR	18411277
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, Microarray, Western blot	18376396
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay, Microarray, Western blot	18376396
MIRT003666	hsa-miR-205-5p	Luciferase reporter assay, Microarray, Western blot	18376396
MIRT000316	hsa-miR-141-3p	Luciferase reporter assay, qRT-PCR, Western blot	19830559
MIRT000316	hsa-miR-141-3p	Luciferase reporter assay, qRT-PCR, Western blot	19830559
MIRT001036	hsa-miR-200c-3p	Immunoblot, Luciferase reporter assay, qRT-PCR	21294122
MIRT001036	hsa-miR-200c-3p	Luciferase reporter assay	20620960
MIRT001036	hsa-miR-200c-3p	Luciferase reporter assay	20620960
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	21049046
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay, qRT-PCR, Western blot	21049046
MIRT001036	hsa-miR-200c-3p	Luciferase reporter assay, qRT-PCR, Western blot	21049046
MIRT000723	hsa-miR-200b-3p	Immunohistochemistry, qRT-PCR	21125666
MIRT001035	hsa-miR-200a-3p	Immunohistochemistry, qRT-PCR	21125666
MIRT001036	hsa-miR-200c-3p	Immunohistochemistry, qRT-PCR	21125666
MIRT006035	hsa-miR-203a-3p	Immunoblot, In situ hybridization, Luciferase reporter assay, qRT-PCR, Western blot	21159887
MIRT001035	hsa-miR-200a-3p	qRT-PCR, Western blot	21389093
MIRT000723	hsa-miR-200b-3p	qRT-PCR, Western blot	21389093
MIRT001036	hsa-miR-200c-3p	qRT-PCR, Western blot	21389093
MIRT006140	hsa-miR-708-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	21852381
MIRT006140	hsa-miR-708-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	21852381
MIRT001036	hsa-miR-200c-3p	qRT-PCR, Western blot	21874049
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay	22311119
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	21529905
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	21529905
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	21529905
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	21529905
MIRT000723	hsa-miR-200b-3p	Immunohistochemistry, qRT-PCR	21125666
MIRT001035	hsa-miR-200a-3p	Immunohistochemistry, qRT-PCR	21125666
MIRT001036	hsa-miR-200c-3p	Immunohistochemistry, qRT-PCR	21125666
MIRT006035	hsa-miR-203a-3p	Immunoblot, In situ hybridization, Luciferase reporter assay, qRT-PCR, Western blot	21159887
MIRT001035	hsa-miR-200a-3p	qRT-PCR, Western blot	21389093
MIRT000723	hsa-miR-200b-3p	qRT-PCR, Western blot	21389093
MIRT001036	hsa-miR-200c-3p	qRT-PCR, Western blot	21389093
MIRT006140	hsa-miR-708-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	21852381
MIRT006140	hsa-miR-708-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	21852381
MIRT001036	hsa-miR-200c-3p	qRT-PCR, Western blot	21874049
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay	22311119
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	21529905
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	21529905
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	21529905
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	21529905
MIRT000723	hsa-miR-200b-3p	Immunohistochemistry, qRT-PCR	21125666
MIRT001035	hsa-miR-200a-3p	Immunohistochemistry, qRT-PCR	21125666
MIRT001036	hsa-miR-200c-3p	Immunohistochemistry, qRT-PCR	21125666
MIRT006035	hsa-miR-203a-3p	Immunoblot, In situ hybridization, Luciferase reporter assay, qRT-PCR, Western blot	21159887
MIRT001035	hsa-miR-200a-3p	qRT-PCR, Western blot	21389093
MIRT000723	hsa-miR-200b-3p	qRT-PCR, Western blot	21389093
MIRT001036	hsa-miR-200c-3p	qRT-PCR, Western blot	21389093
MIRT006140	hsa-miR-708-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	21852381
MIRT006140	hsa-miR-708-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	21852381
MIRT001036	hsa-miR-200c-3p	qRT-PCR, Western blot	21874049
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay	22311119
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	21529905
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	21529905
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	21529905
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, qRT-PCR, Western blot	21529905
MIRT001036	hsa-miR-200c-3p	Luciferase reporter assay, Western blot	22569286
MIRT007099	hsa-miR-153-3p	Luciferase reporter assay, qRT-PCR, Western blot	23188671
MIRT001035	hsa-miR-200a-3p	Western blot;qRT-PCR	19931509
MIRT021691	hsa-miR-138-5p	Reporter assay;qRT-PCR	21770894
MIRT024209	hsa-miR-221-3p	Reporter assay;Western blot;qRT-PCR	20516212
MIRT047309	hsa-miR-181a-5p	CLASH	23622248
MIRT044428	hsa-miR-320a	CLASH	23622248
MIRT000316	hsa-miR-141-3p	Luciferase reporter assay	24245745
MIRT000723	hsa-miR-200b-3p	qRT-PCR	22294131
MIRT052961	hsa-miR-215-5p	Microarray, qRT-PCR, Western blot	22033272
MIRT053133	hsa-miR-335-5p	Luciferase reporter assay, qRT-PCR, Western blot	24829139
MIRT001035	hsa-miR-200a-3p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	23386720
MIRT000723	hsa-miR-200b-3p	In situ hybridization, qRT-PCR, Western blot	22012804
MIRT001036	hsa-miR-200c-3p	Microarray	23807165
MIRT001035	hsa-miR-200a-3p	Immunofluorescence, Immunohistochemistry, In situ hybridization, qRT-PCR, Western blot	23381389
MIRT000723	hsa-miR-200b-3p	Immunohistochemistry, Luciferase reporter assay, Microarray, Western blot	25270520
MIRT000723	hsa-miR-200b-3p	Immunohistochemistry, Microarray, qRT-PCR, Western blot	25411357
MIRT001036	hsa-miR-200c-3p	Luciferase reporter assay, qRT-PCR, Western blot	25502084
MIRT001036	hsa-miR-200c-3p	Luciferase reporter assay, qRT-PCR, Western blot	25502084
MIRT000316	hsa-miR-141-3p	Luciferase reporter assay, qRT-PCR, Western blot	25502084
MIRT000316	hsa-miR-141-3p	Luciferase reporter assay, qRT-PCR, Western blot	25502084
MIRT054444	hsa-miR-4782-3p	Luciferase reporter assay, qRT-PCR, Western blot	24556800
MIRT054444	hsa-miR-4782-3p	Luciferase reporter assay, qRT-PCR, Western blot	24556800
MIRT001035	hsa-miR-200a-3p	Flow, Immunohistochemistry, Luciferase reporter assay, Microarray, qRT-PCR, Western blot	24518294
MIRT001035	hsa-miR-200a-3p	Immunofluorescence, Microarray, qRT-PCR, Western blot	22012804
MIRT001035	hsa-miR-200a-3p	Immunoblot, In situ hybridization, Microarray	24280074
MIRT054930	hsa-miR-101-3p	Immunofluorescence, Luciferase reporter assay, Western blot	24677166
MIRT003666	hsa-miR-205-5p	ChIP-seq, LacZ reporter assay	23474752
MIRT003666	hsa-miR-205-5p	ChIP-seq, LacZ reporter assay	23474752
MIRT003666	hsa-miR-205-5p	ChIP-seq, LacZ reporter assay	23474752
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay, qRT-PCR, Western blot	23408168
MIRT000723	hsa-miR-200b-3p	Flow, Immunohistochemistry, Luciferase reporter assay, Microarray, qRT-PCR, Western blot	24769353
MIRT000723	hsa-miR-200b-3p	Flow, Immunohistochemistry, Luciferase reporter assay, Microarray, qRT-PCR, Western blot	24769353
MIRT001035	hsa-miR-200a-3p	qRT-PCR, Western blot	24127332
MIRT001035	hsa-miR-200a-3p	qRT-PCR, Western blot	24127332
MIRT001036	hsa-miR-200c-3p	qRT-PCR, Western blot	24127332
MIRT438341	hsa-miR-338-3p	Immunohistochemistry, In situ hybridization, Luciferase reporter assay, qRT-PCR, Western blot	25945841
MIRT438341	hsa-miR-338-3p	Immunohistochemistry, In situ hybridization, Luciferase reporter assay, qRT-PCR, Western blot	25945841
MIRT000316	hsa-miR-141-3p	Luciferase reporter assay, qRT-PCR, Western blot	25975736
MIRT000316	hsa-miR-141-3p	Luciferase reporter assay, qRT-PCR, Western blot	25975736
MIRT001035	hsa-miR-200a-3p	qRT-PCR, Western blot	24127332
MIRT001035	hsa-miR-200a-3p	qRT-PCR, Western blot	24127332
MIRT001036	hsa-miR-200c-3p	qRT-PCR, Western blot	24127332
MIRT438341	hsa-miR-338-3p	Immunohistochemistry, In situ hybridization, Luciferase reporter assay, qRT-PCR, Western blot	25945841
MIRT438341	hsa-miR-338-3p	Immunohistochemistry, In situ hybridization, Luciferase reporter assay, qRT-PCR, Western blot	25945841
MIRT000316	hsa-miR-141-3p	Luciferase reporter assay, qRT-PCR, Western blot	25975736
MIRT000316	hsa-miR-141-3p	Luciferase reporter assay, qRT-PCR, Western blot	25975736
MIRT439136	hsa-let-7d-5p	TRAP	24510096
MIRT439109	hsa-miR-125a-5p	TRAP	24510096
MIRT000316	hsa-miR-141-3p	TRAP	24510096
MIRT439106	hsa-miR-16-5p	TRAP	24510096
MIRT001036	hsa-miR-200c-3p	TRAP	24510096
MIRT439100	hsa-miR-222-3p	TRAP	24510096
MIRT439098	hsa-miR-30c-5p	TRAP	24510096
MIRT439095	hsa-miR-30e-5p	TRAP	24510096
MIRT439094	hsa-miR-34a-5p	TRAP	24510096
MIRT439136	hsa-let-7d-5p	TRAP	24510096
MIRT439109	hsa-miR-125a-5p	TRAP	24510096
MIRT000316	hsa-miR-141-3p	TRAP	24510096
MIRT439106	hsa-miR-16-5p	TRAP	24510096
MIRT001036	hsa-miR-200c-3p	TRAP	24510096
MIRT439100	hsa-miR-222-3p	TRAP	24510096
MIRT439098	hsa-miR-30c-5p	TRAP	24510096
MIRT439095	hsa-miR-30e-5p	TRAP	24510096
MIRT439094	hsa-miR-34a-5p	TRAP	24510096
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay, qRT-PCR, Western blot	26648487
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay, qRT-PCR, Western blot	26648487
MIRT731798	hsa-miR-144-3p	Luciferase reporter assay, qRT-PCR, Western blot	27785072
MIRT731798	hsa-miR-144-3p	Luciferase reporter assay, qRT-PCR, Western blot	27785072
MIRT000048	hsa-miR-429	Luciferase reporter assay, qRT-PCR, Western blot	26472725
MIRT000048	hsa-miR-429	Luciferase reporter assay, qRT-PCR, Western blot	26472725
MIRT000723	hsa-miR-200b-3p	Western blot	27373709
MIRT203612	hsa-miR-590-3p	Luciferase reporter assay, qRT-PCR, Western blot	26556542
MIRT203612	hsa-miR-590-3p	Luciferase reporter assay, qRT-PCR, Western blot	26556542
MIRT054930	hsa-miR-101-3p	Microarray	28416776
MIRT054930	hsa-miR-101-3p	Luciferase reporter assay, qRT-PCR, Western blot	28109909
MIRT000316	hsa-miR-141-3p	Microarray, RNA-seq, qRT-PCR	31665050
MIRT003666	hsa-miR-205-5p	Microarray, RNA-seq, qRT-PCR	31665050
MIRT000723	hsa-miR-200b-3p	Microarray, RNA-seq, qRT-PCR	31665050
MIRT000723	hsa-miR-200b-3p	Microarray, RNA-seq, qRT-PCR	31665050
MIRT732779	hsa-miR-132-3p	Western blotting, qRT-PCR, Flow cytometry	32500672
MIRT735581	hsa-miR-545-3p	Luciferase reporter assay, Western blotting, qRT-PCR, ELISA	32104945
MIRT736050	hsa-miR-192-5p	Western blotting, qRT-PCR	33066331
MIRT439100	hsa-miR-222-3p	Western blotting, qRT-PCR	34018840
MIRT736670	hsa-miR-493-5p	Luciferase reporter assay, Western blotting, qRT-PCR	32463882
MIRT737400	hsa-miR-124-3p	Luciferase reporter assay, RNA-seq, qRT-PCR	32046742
MIRT736050	hsa-miR-192-5p	Luciferase reporter assay, Western blotting, qRT-PCR	34880446
MIRT000723	hsa-miR-200b-3p	Luciferase reporter assay, Western blotting, qRT-PCR	34880446
MIRT001035	hsa-miR-200a-3p	Luciferase reporter assay, Western blotting, qRT-PCR	34880446
MIRT000723	hsa-miR-200b-3p	Western blotting, qRT-PCR	37681509
MIRT756206	hsa-miR-30a-5p	Western blotting, Microarray, qRT-PCR	37915096
MIRT006035	hsa-miR-203a-3p	qRT-PCR	35453574
MIRT1509255	hsa-miR-1301	CLIP-seq
MIRT1509256	hsa-miR-3622a-3p	CLIP-seq
MIRT1509257	hsa-miR-3622b-3p	CLIP-seq
MIRT1509258	hsa-miR-3671	CLIP-seq
MIRT1509259	hsa-miR-4457	CLIP-seq
MIRT1509260	hsa-miR-4520a-3p	CLIP-seq
MIRT1509261	hsa-miR-4520b-3p	CLIP-seq
MIRT1509262	hsa-miR-4660	CLIP-seq
MIRT1509263	hsa-miR-4661-5p	CLIP-seq
MIRT1509264	hsa-miR-4679	CLIP-seq
MIRT1509265	hsa-miR-5047	CLIP-seq
MIRT1509266	hsa-miR-5096	CLIP-seq
MIRT1509267	hsa-miR-513b	CLIP-seq
MIRT1509268	hsa-miR-556-3p	CLIP-seq
MIRT1509269	hsa-miR-1245b-5p	CLIP-seq
MIRT1509270	hsa-miR-1295	CLIP-seq
MIRT1509271	hsa-miR-129-5p	CLIP-seq
MIRT1509272	hsa-miR-141	CLIP-seq
MIRT1509273	hsa-miR-200a	CLIP-seq
MIRT1509274	hsa-miR-3142	CLIP-seq
MIRT1509275	hsa-miR-3150a-5p	CLIP-seq
MIRT1509276	hsa-miR-3150b-5p	CLIP-seq
MIRT1509277	hsa-miR-3653	CLIP-seq
MIRT1509278	hsa-miR-3658	CLIP-seq
MIRT1509279	hsa-miR-3921	CLIP-seq
MIRT1509280	hsa-miR-410	CLIP-seq
MIRT1509281	hsa-miR-4282	CLIP-seq
MIRT1509282	hsa-miR-4328	CLIP-seq
MIRT1509283	hsa-miR-4424	CLIP-seq
MIRT1509284	hsa-miR-4474-5p	CLIP-seq
MIRT1509260	hsa-miR-4520a-3p	CLIP-seq
MIRT1509261	hsa-miR-4520b-3p	CLIP-seq
MIRT1509285	hsa-miR-4539	CLIP-seq
MIRT1509286	hsa-miR-4653-5p	CLIP-seq
MIRT1509263	hsa-miR-4661-5p	CLIP-seq
MIRT1509287	hsa-miR-513a-3p	CLIP-seq
MIRT1509288	hsa-miR-548aa	CLIP-seq
MIRT1509289	hsa-miR-548ac	CLIP-seq
MIRT1509290	hsa-miR-548d-3p	CLIP-seq
MIRT1509291	hsa-miR-548z	CLIP-seq
MIRT1509292	hsa-miR-582-5p	CLIP-seq
MIRT1509293	hsa-miR-593	CLIP-seq
MIRT1509281	hsa-miR-4282	CLIP-seq
MIRT2153392	hsa-miR-1305	CLIP-seq
MIRT2153393	hsa-miR-1825	CLIP-seq
MIRT2153394	hsa-miR-199a-5p	CLIP-seq
MIRT2153395	hsa-miR-199b-5p	CLIP-seq
MIRT1509277	hsa-miR-3653	CLIP-seq
MIRT1509278	hsa-miR-3658	CLIP-seq
MIRT1509258	hsa-miR-3671	CLIP-seq
MIRT2153396	hsa-miR-3942-3p	CLIP-seq
MIRT2153397	hsa-miR-4307	CLIP-seq
MIRT2153398	hsa-miR-4519	CLIP-seq
MIRT2153399	hsa-miR-4659a-3p	CLIP-seq
MIRT2153400	hsa-miR-4659b-3p	CLIP-seq
MIRT2153401	hsa-miR-4716-5p	CLIP-seq
MIRT2153402	hsa-miR-498	CLIP-seq
MIRT2153403	hsa-miR-576-5p	CLIP-seq
MIRT2153404	hsa-miR-577	CLIP-seq
MIRT2153405	hsa-miR-656	CLIP-seq
MIRT2153392	hsa-miR-1305	CLIP-seq
MIRT2373673	hsa-miR-1913	CLIP-seq
MIRT2373674	hsa-miR-3127-3p	CLIP-seq
MIRT2373675	hsa-miR-324-3p	CLIP-seq
MIRT2373676	hsa-miR-4313	CLIP-seq
MIRT2153398	hsa-miR-4519	CLIP-seq
MIRT2373677	hsa-miR-487a	CLIP-seq
MIRT2153402	hsa-miR-498	CLIP-seq
MIRT1509281	hsa-miR-4282	CLIP-seq
MIRT2463894	hsa-miR-297	CLIP-seq
MIRT2463895	hsa-miR-4652-3p	CLIP-seq
MIRT2463896	hsa-miR-501-5p	CLIP-seq
MIRT2463897	hsa-miR-567	CLIP-seq
MIRT2666343	hsa-miR-1236	CLIP-seq
MIRT2666344	hsa-miR-1243	CLIP-seq
MIRT2666345	hsa-miR-1263	CLIP-seq
MIRT2666346	hsa-miR-1273d	CLIP-seq
MIRT2666347	hsa-miR-127-5p	CLIP-seq
MIRT2153392	hsa-miR-1305	CLIP-seq
MIRT2666348	hsa-miR-138	CLIP-seq
MIRT1509272	hsa-miR-141	CLIP-seq
MIRT2666349	hsa-miR-142-3p	CLIP-seq
MIRT2666350	hsa-miR-153	CLIP-seq
MIRT2666351	hsa-miR-154	CLIP-seq
MIRT2666352	hsa-miR-183	CLIP-seq
MIRT2666353	hsa-miR-19a	CLIP-seq
MIRT2666354	hsa-miR-19b	CLIP-seq
MIRT1509273	hsa-miR-200a	CLIP-seq
MIRT2666355	hsa-miR-223	CLIP-seq
MIRT2666356	hsa-miR-2392	CLIP-seq
MIRT2666357	hsa-miR-25	CLIP-seq
MIRT2666358	hsa-miR-298	CLIP-seq
MIRT2666359	hsa-miR-302f	CLIP-seq
MIRT2666360	hsa-miR-30a	CLIP-seq
MIRT2666361	hsa-miR-30b	CLIP-seq
MIRT2666362	hsa-miR-30c	CLIP-seq
MIRT2666363	hsa-miR-30d	CLIP-seq
MIRT2666364	hsa-miR-30e	CLIP-seq
MIRT2666365	hsa-miR-3119	CLIP-seq
MIRT2373674	hsa-miR-3127-3p	CLIP-seq
MIRT2666366	hsa-miR-3133	CLIP-seq
MIRT2666367	hsa-miR-3148	CLIP-seq
MIRT2666368	hsa-miR-3152-5p	CLIP-seq
MIRT2666369	hsa-miR-32	CLIP-seq
MIRT2666370	hsa-miR-320e	CLIP-seq
MIRT2666371	hsa-miR-33a	CLIP-seq
MIRT2666372	hsa-miR-33b	CLIP-seq
MIRT2666373	hsa-miR-3613-3p	CLIP-seq
MIRT2666374	hsa-miR-3622a-5p	CLIP-seq
MIRT2666375	hsa-miR-363	CLIP-seq
MIRT2666376	hsa-miR-3654	CLIP-seq
MIRT2666377	hsa-miR-367	CLIP-seq
MIRT2666378	hsa-miR-3678-3p	CLIP-seq
MIRT2666379	hsa-miR-380	CLIP-seq
MIRT2666380	hsa-miR-3977	CLIP-seq
MIRT2153397	hsa-miR-4307	CLIP-seq
MIRT2666381	hsa-miR-4464	CLIP-seq
MIRT2666382	hsa-miR-4476	CLIP-seq
MIRT2666383	hsa-miR-448	CLIP-seq
MIRT2666384	hsa-miR-4495	CLIP-seq
MIRT2153398	hsa-miR-4519	CLIP-seq
MIRT2666385	hsa-miR-4521	CLIP-seq
MIRT2666386	hsa-miR-4666-5p	CLIP-seq
MIRT2666387	hsa-miR-4697-3p	CLIP-seq
MIRT2153401	hsa-miR-4716-5p	CLIP-seq
MIRT2666388	hsa-miR-4748	CLIP-seq
MIRT2666389	hsa-miR-4773	CLIP-seq
MIRT2666390	hsa-miR-4792	CLIP-seq
MIRT2666391	hsa-miR-4804-3p	CLIP-seq
MIRT2153402	hsa-miR-498	CLIP-seq
MIRT2666392	hsa-miR-517b	CLIP-seq
MIRT2666393	hsa-miR-518a-5p	CLIP-seq
MIRT2666394	hsa-miR-527	CLIP-seq
MIRT2666395	hsa-miR-548ag	CLIP-seq
MIRT2666396	hsa-miR-548ai	CLIP-seq
MIRT2666397	hsa-miR-548k	CLIP-seq
MIRT2666398	hsa-miR-548m	CLIP-seq
MIRT2666399	hsa-miR-548n	CLIP-seq
MIRT2666400	hsa-miR-548q	CLIP-seq
MIRT2666401	hsa-miR-586	CLIP-seq
MIRT2666402	hsa-miR-624	CLIP-seq
MIRT2153405	hsa-miR-656	CLIP-seq
MIRT2666403	hsa-miR-875-3p	CLIP-seq
MIRT2666404	hsa-miR-92a	CLIP-seq
MIRT2666405	hsa-miR-92b	CLIP-seq
MIRT1509272	hsa-miR-141	CLIP-seq
MIRT1509273	hsa-miR-200a	CLIP-seq
MIRT2666343	hsa-miR-1236	CLIP-seq
MIRT2666346	hsa-miR-1273d	CLIP-seq
MIRT2666347	hsa-miR-127-5p	CLIP-seq
MIRT2153392	hsa-miR-1305	CLIP-seq
MIRT2666348	hsa-miR-138	CLIP-seq
MIRT1509272	hsa-miR-141	CLIP-seq
MIRT2666350	hsa-miR-153	CLIP-seq
MIRT2666352	hsa-miR-183	CLIP-seq
MIRT2666353	hsa-miR-19a	CLIP-seq
MIRT2666354	hsa-miR-19b	CLIP-seq
MIRT1509273	hsa-miR-200a	CLIP-seq
MIRT2666356	hsa-miR-2392	CLIP-seq
MIRT2666357	hsa-miR-25	CLIP-seq
MIRT2666358	hsa-miR-298	CLIP-seq
MIRT2666359	hsa-miR-302f	CLIP-seq
MIRT2666366	hsa-miR-3133	CLIP-seq
MIRT2666369	hsa-miR-32	CLIP-seq
MIRT2666370	hsa-miR-320e	CLIP-seq
MIRT2666373	hsa-miR-3613-3p	CLIP-seq
MIRT2666374	hsa-miR-3622a-5p	CLIP-seq
MIRT2666375	hsa-miR-363	CLIP-seq
MIRT2666377	hsa-miR-367	CLIP-seq
MIRT2666378	hsa-miR-3678-3p	CLIP-seq
MIRT2666380	hsa-miR-3977	CLIP-seq
MIRT2153397	hsa-miR-4307	CLIP-seq
MIRT2666381	hsa-miR-4464	CLIP-seq
MIRT2666383	hsa-miR-448	CLIP-seq
MIRT2153398	hsa-miR-4519	CLIP-seq
MIRT2666386	hsa-miR-4666-5p	CLIP-seq
MIRT2153401	hsa-miR-4716-5p	CLIP-seq
MIRT2666388	hsa-miR-4748	CLIP-seq
MIRT2666389	hsa-miR-4773	CLIP-seq
MIRT2666390	hsa-miR-4792	CLIP-seq
MIRT2666391	hsa-miR-4804-3p	CLIP-seq
MIRT2153402	hsa-miR-498	CLIP-seq
MIRT2666392	hsa-miR-517b	CLIP-seq
MIRT2666393	hsa-miR-518a-5p	CLIP-seq
MIRT2666394	hsa-miR-527	CLIP-seq
MIRT2666395	hsa-miR-548ag	CLIP-seq
MIRT2666396	hsa-miR-548ai	CLIP-seq
MIRT2666397	hsa-miR-548k	CLIP-seq
MIRT2666398	hsa-miR-548m	CLIP-seq
MIRT2666399	hsa-miR-548n	CLIP-seq
MIRT2666400	hsa-miR-548q	CLIP-seq
MIRT2666402	hsa-miR-624	CLIP-seq
MIRT2666404	hsa-miR-92a	CLIP-seq
MIRT2666405	hsa-miR-92b	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
PCGF2	Repression	23474752

Show/Hide all(70)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	12837246, 20516212
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IMP	24769727
GO:0000785	Component	Chromatin	IDA	20516212
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	20516212
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	20516212
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IEA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IEA
GO:0001755	Process	Neural crest cell migration	IEA
GO:0001756	Process	Somitogenesis	IEA
GO:0001843	Process	Neural tube closure	IEA
GO:0001935	Process	Endothelial cell proliferation	IEA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	26028330
GO:0005634	Component	Nucleus	IDA	24769727
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005694	Component	Chromosome	IEA
GO:0005730	Component	Nucleolus	IDA
GO:0005886	Component	Plasma membrane	IDA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007399	Process	Nervous system development	NAS	11279515
GO:0007417	Process	Central nervous system development	IBA
GO:0007417	Process	Central nervous system development	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0010764	Process	Negative regulation of fibroblast migration	IEA
GO:0019208	Function	Phosphatase regulator activity	NAS	11477103
GO:0021540	Process	Corpus callosum morphogenesis	IEA
GO:0021766	Process	Hippocampus development	IEA
GO:0021846	Process	Cell proliferation in forebrain	IEA
GO:0021957	Process	Corticospinal tract morphogenesis	IEA
GO:0030177	Process	Positive regulation of Wnt signaling pathway	IEA
GO:0030177	Process	Positive regulation of Wnt signaling pathway	IEA
GO:0030511	Process	Positive regulation of transforming growth factor beta receptor signaling pathway	IMP	30592286
GO:0036446	Process	Myofibroblast differentiation	IEA
GO:0043149	Process	Stress fiber assembly	IEA
GO:0043542	Process	Endothelial cell migration	IEA
GO:0045636	Process	Positive regulation of melanocyte differentiation	IEA
GO:0045636	Process	Positive regulation of melanocyte differentiation	ISS	24769727
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IMP	24769727
GO:0046872	Function	Metal ion binding	IEA
GO:0048023	Process	Positive regulation of melanin biosynthetic process	IC	24769727
GO:0048023	Process	Positive regulation of melanin biosynthetic process	IEA
GO:0048066	Process	Developmental pigmentation	IEA
GO:0048066	Process	Developmental pigmentation	ISS	24769727
GO:0048143	Process	Astrocyte activation	IEA
GO:0048598	Process	Embryonic morphogenesis	IEA
GO:0048668	Process	Collateral sprouting	IEA
GO:0050772	Process	Positive regulation of axonogenesis	IEA
GO:0061373	Process	Mammillary axonal complex development	IEA
GO:0070269	Process	Pyroptotic inflammatory response	IEA
GO:0070412	Function	R-SMAD binding	IEA
GO:0072537	Process	Fibroblast activation	IEA
GO:0090263	Process	Positive regulation of canonical Wnt signaling pathway	IMP	30592286
GO:0090649	Process	Response to oxygen-glucose deprivation	IEA
GO:0097324	Process	Melanocyte migration	IEA
GO:0097324	Process	Melanocyte migration	ISS	24769727
GO:1902748	Process	Positive regulation of lens fiber cell differentiation	IEA
GO:1903056	Process	Regulation of melanosome organization	IEA
GO:1903056	Process	Regulation of melanosome organization	ISS	24769727
GO:1904330	Process	Positive regulation of myofibroblast contraction	IEA
GO:1904520	Process	Regulation of myofibroblast cell apoptotic process	IEA
GO:1905603	Process	Regulation of blood-brain barrier permeability	IEA

MIM	HGNC	e!Ensembl
605802	14881	ENSG00000169554

Protein

UniProt ID

O60315

Protein name

Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (SMADIP1) (Zinc finger homeobox protein 1b)

Protein function

Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters (PubMed:16061479, PubMed:20516212). Represses transcription of E-cadherin (PubMed:16061479). Represses expression of MEOX2 (PubMed:20516212). {ECO:0000269|Pu

PDB

2DA7

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05605	zf-Di19	209 → 270	Drought induced 19 protein (Di19), zinc-binding	Domain
PF00096	zf-C2H2	282 → 304	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	310 → 331	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	1055 → 1076	Zinc finger, C2H2 type	Domain

Sequence

MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQET
SPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTM
GPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAP
EELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEEN
FSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEH
LRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSS
PTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGL
GATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKA
EEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACL
QSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHE
RYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLK
AYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSN
PPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRS
NTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKAS
SISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPP
QSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQG
FQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYE
HTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSY
CKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEH
EKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKME
TKSDHEEDNMEDGM

Sequence length

1214

Interactions

View interactions

	KEGG
	MicroRNAs in cancer

Show/Hide Causal Diseases (2)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Mowat-Wilson Syndrome	mowat-wilson syndrome	rs786204814, rs398124274, rs1553961598, rs1553961747, rs1560604977, rs794727924, rs727504226, rs587776605, rs1573716158, rs886041989, rs786204810, rs786204807, rs398124280, rs1553961510, rs1553964145 View all (100 more)	N/A
Mental retardation	intellectual disability	rs587784566, rs886041989	N/A

Show/Hide Unknown Diseases (7)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Coronary artery disease	Coronary artery disease	N/A	N/A	GWAS
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Heart Failure	Heart failure	N/A	N/A	GWAS
Lennox-Gastaut Syndrome	lennox-gastaut syndrome	N/A	N/A	ClinVar
Myocardial Infarction	Myocardial infarction	N/A	N/A	GWAS
Renal Carcinoma	Renal cell carcinoma	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (127)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Abdominal Pain	Associate	37735378
Adenocarcinoma Mucinous	Associate	32840168
Adenocarcinoma of Lung	Associate	27733346
Adenocarcinoma of Lung	Inhibit	29116025
Agenesis of Corpus Callosum	Associate	11595972, 27831545
Alcoholism	Associate	28040410
Anisometropia	Associate	37266952
Ascites	Associate	34211089
Astigmatism	Associate	36676725
Atherosclerosis	Associate	36720950
Axial osteomalacia	Associate	37266952
Bicuspid Aortic Valve Disease	Associate	30280445
Brain Neoplasms	Associate	33572092
Breast Neoplasms	Associate	15742334, 16314317, 16568083, 25053741, 25762639, 26823172, 28107418, 28247944, 29368542, 29666469, 30979827, 31257481, 33280520, 34231077, 34582659, 35986741, 37575267, 38078907 View all (3 more)
Breast Neoplasms	Stimulate	37088469
Carcinogenesis	Associate	21645397
Carcinoma Ductal	Associate	30760857
Carcinoma Embryonal	Associate	12175509
Carcinoma Endometrioid	Associate	29060924
Carcinoma Hepatocellular	Associate	15026811, 21645397, 22393452, 25008569, 25797260, 26156804, 27748842, 27861158, 31298368, 32965165, 34018840, 34496784, 37138218, 38538524
Carcinoma Hepatocellular	Inhibit	37564197
Carcinoma Non Small Cell Lung	Associate	19846957, 24626466, 27453416, 31244281, 31799665, 32329850, 34107856, 34839824, 37566546
Carcinoma Non Small Cell Lung	Stimulate	31695021, 32611283
Carcinoma Non Small Cell Lung	Inhibit	36969247
Carcinoma Ovarian Epithelial	Inhibit	28623900
Carcinoma Ovarian Epithelial	Associate	34211089
Carcinoma Renal Cell	Associate	17060462, 23658743, 31257481, 31599407, 32046742
Carcinoma Squamous Cell	Associate	36969247
Cataract	Associate	36676725
Cholangiocarcinoma	Associate	28423728
Cirrhosis Familial	Associate	28423728
Colorectal Neoplasms	Associate	23372686, 24914372, 29504907, 30646224, 31364113, 31698657, 32391554, 33084522, 34965191
Colorectal Neoplasms	Stimulate	32277632
Congenital Abnormalities	Associate	21712996, 37735378, 38350246
Coronary Artery Disease	Associate	32919281
COVID 19	Associate	35866388
Death	Associate	32150457
Developmental Disabilities	Associate	11592033, 26993267
Down Syndrome	Associate	33318568
Drug Related Side Effects and Adverse Reactions	Inhibit	33572092
Endometrial Neoplasms	Associate	33457409
Endometrial Neoplasms	Inhibit	34970423
Endometriosis	Associate	32802844
Enteritis	Associate	12175509
Epilepsy	Associate	11592033, 26993267, 27831545, 33870748, 38350246
Esophageal Squamous Cell Carcinoma	Associate	21426561, 32194853, 32495874, 34551777, 34866524
Facial Dysmorphism with Multiple Malformations	Associate	11595972
Fetal akinesia syndrome X linked	Associate	31680123
Gingival Overgrowth	Associate	32471743
Gingivitis	Associate	32471743
Glioblastoma	Associate	25833697, 29476046, 33572092, 36762036
Glioma	Associate	22761708, 33572092
Glioma	Inhibit	32857719
Heart Defects Congenital	Associate	12175509, 25205790, 37735378
Heterotaxy Syndrome	Associate	24401652
Hirschsprung Disease	Associate	11592033, 11595972, 12175509, 17932455, 19925665, 21712996, 37679133
Hypospadias	Associate	11595972
Hypoxia Brain	Associate	38563293
Immunologic Deficiency Syndromes	Associate	11592033
Inflammation	Associate	25762639
Inflammatory Breast Neoplasms	Associate	32708601
Intellectual Disability	Associate	11592033, 11595972, 24058414, 26933844, 38350246
Leiomyoma	Associate	22685266
Leukemia Biphenotypic Acute	Associate	37981088
Leukemia Myeloid Acute	Associate	26186352, 37313984
Leukemia Prolymphocytic T Cell	Associate	33596640
Lung Neoplasms	Associate	20980099, 24626466, 29371906
Lung Neoplasms	Inhibit	33627769
Lymphatic Metastasis	Stimulate	25989272, 31695021
Lymphatic Metastasis	Associate	27748842
Melanoma	Associate	37475109
Mental Disorders	Associate	37735378
Mental Retardation Autosomal Dominant 3	Associate	11592033
Methylmalonic Aciduria and Homocystinuria CblF Type	Associate	35709987
Microcephaly	Associate	11595972
Midline granulomatosis	Associate	12175509
Mohr Tranebjaerg syndrome	Associate	27733346
Mouth Neoplasms	Associate	36849997
Mowat Wilson syndrome	Associate	17932455, 18812405, 20125191, 20145308, 20428734, 24058414, 25608121, 27831545, 29300384, 31376723, 32519765, 32539836, 33982229, 35709987, 36676725, 37735378, 37890485, 38350246 View all (3 more)
Myopia	Associate	28848321, 38243264
Nasopharyngeal Carcinoma	Associate	30353102, 31257481
Neoplasm Metastasis	Associate	19706487, 23150175, 24914372, 25053741, 25797260, 25833697, 25894377, 26646296, 27453416, 31298368, 34231077, 34573283, 38078907
Neoplasm Metastasis	Stimulate	25409617, 31128021, 32277632, 34211089
Neoplasm Metastasis	Inhibit	27748842, 37564197
Neoplasms	Associate	12414534, 15742334, 17855508, 18381893, 19486012, 19846957, 22586443, 23150175, 23376074, 24796549, 24814677, 25913622, 26136338, 26646296, 26764010 View all (16 more)
Neoplasms	Stimulate	15026811, 25989272, 30646224, 31128021, 31698657, 32277632
Neoplasms	Inhibit	27748842, 36969247, 37566546
Neural crest tumor	Associate	37890485
Nevus	Associate	37475109
Nevus Pigmented	Associate	30359577
Obesity	Associate	25630869
Optic Atrophy	Associate	36676725
Optic Nerve Diseases	Associate	36676725
Oral Submucous Fibrosis	Associate	29893466
Organizing Pneumonia	Associate	38350246
Osteosarcoma	Associate	30692230, 32633340
Ovarian Diseases	Associate	34211089
Ovarian Neoplasms	Associate	19486012, 19854497, 24677166, 25894377, 26136338, 26824454, 27563817, 29952249, 32316405, 34211089, 35953860
Pancreatic Neoplasms	Associate	20551052, 25409617, 25989272, 30318866
Pancreatic Neoplasms	Stimulate	36420274
Pelvic Inflammatory Disease	Associate	33457409
Periodontitis	Associate	25630869
Peripheral Arterial Disease	Associate	31070467
Peritonitis	Associate	34211089
Pleural Effusion	Associate	15742334
Pre Eclampsia	Associate	33318568
Precursor B Cell Lymphoblastic Leukemia Lymphoma	Associate	30487223
Prostatic Neoplasms	Associate	23024790, 28133913
Rectal Neoplasms	Associate	33124951
Rubinstein Taybi Syndrome	Associate	20125191
Sarcoma Ewing	Associate	37597508
Self Mutilation	Associate	26933844
Small Cell Lung Carcinoma	Associate	35927660
Spastic Paraplegia Hereditary	Associate	28040410
Squamous Cell Carcinoma of Head and Neck	Associate	26214683, 29150940
Squamous Cell Carcinoma of Head and Neck	Stimulate	30957184
Stomach Diseases	Associate	28485807
Stomach Neoplasms	Associate	12414534, 16314317, 24885194, 25913622, 25945841, 25975736, 28485807, 29138864, 31128021, 33124951, 35874675, 36580668
Strabismus	Associate	36676725
Tertiary Lymphoid Structures	Associate	24814677
Thakker Donnai syndrome	Associate	12175509
Triple Negative Breast Neoplasms	Associate	25762639
Urinary Bladder Neoplasms	Associate	19706487, 26152796, 26544536, 26646296, 30352837, 31746333
Urogenital Abnormalities	Associate	37735378
Uterine Cervical Neoplasms	Associate	29523224
Vascular System Injuries	Associate	28551696
Vision Disorders	Associate	36676725

ZEB2 (zinc finger E-box binding homeobox 2)