Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9833
Gene name Gene Name - the full gene name approved by the HGNC.	Maternal embryonic leucine zipper kinase
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MELK
Synonyms (NCBI Gene) Gene synonyms aliases	HPK38
Chromosome Chromosome number	9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	9p13.2

Show/Hide all(349)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016391	hsa-miR-193b-3p	Microarray	20304954
MIRT628572	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT628571	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT628570	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT628569	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT628568	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT628567	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT628566	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT628565	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT656330	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT656329	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT656328	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT656327	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT656326	hsa-miR-302e	HITS-CLIP	23824327
MIRT656325	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT656324	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT656323	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT656322	hsa-miR-520b	HITS-CLIP	23824327
MIRT656321	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT656320	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT656319	hsa-miR-520e	HITS-CLIP	23824327
MIRT628564	hsa-miR-3973	HITS-CLIP	23824327
MIRT628563	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT628562	hsa-miR-520h	HITS-CLIP	23824327
MIRT628561	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT628560	hsa-miR-764	HITS-CLIP	23824327
MIRT628559	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT628558	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT628557	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT628556	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT674106	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT674105	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT674104	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT535982	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT535981	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT628555	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT628554	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT628553	hsa-miR-640	HITS-CLIP	23824327
MIRT628561	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT628560	hsa-miR-764	HITS-CLIP	23824327
MIRT628559	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT628558	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT628557	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT628556	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT535982	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT669869	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT669868	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669867	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT628555	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT628554	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT669866	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT628553	hsa-miR-640	HITS-CLIP	23824327
MIRT617360	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT617358	hsa-miR-4712-5p	HITS-CLIP	23824327
MIRT617357	hsa-miR-770-5p	HITS-CLIP	23824327
MIRT617356	hsa-miR-3925-3p	HITS-CLIP	23824327
MIRT617355	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT617354	hsa-miR-5186	HITS-CLIP	23824327
MIRT617353	hsa-miR-4252	HITS-CLIP	23824327
MIRT617352	hsa-miR-3115	HITS-CLIP	23824327
MIRT617351	hsa-miR-7703	HITS-CLIP	23824327
MIRT638505	hsa-miR-1262	HITS-CLIP	23824327
MIRT638504	hsa-miR-4701-3p	HITS-CLIP	23824327
MIRT638503	hsa-miR-6736-5p	HITS-CLIP	23824327
MIRT628572	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT628571	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT628570	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT628569	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT628568	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT628567	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT628566	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT628565	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT656330	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT656329	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT656328	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT656327	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT656326	hsa-miR-302e	HITS-CLIP	23824327
MIRT656325	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT656324	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT656323	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT656322	hsa-miR-520b	HITS-CLIP	23824327
MIRT656321	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT656320	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT656319	hsa-miR-520e	HITS-CLIP	23824327
MIRT628564	hsa-miR-3973	HITS-CLIP	23824327
MIRT628563	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT628562	hsa-miR-520h	HITS-CLIP	23824327
MIRT628561	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT628560	hsa-miR-764	HITS-CLIP	23824327
MIRT628559	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT628558	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT628557	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT628556	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT535982	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT628555	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT628554	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT628553	hsa-miR-640	HITS-CLIP	23824327
MIRT617360	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT617359	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT617358	hsa-miR-4712-5p	HITS-CLIP	23824327
MIRT617357	hsa-miR-770-5p	HITS-CLIP	23824327
MIRT617356	hsa-miR-3925-3p	HITS-CLIP	23824327
MIRT617355	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT617354	hsa-miR-5186	HITS-CLIP	23824327
MIRT617353	hsa-miR-4252	HITS-CLIP	23824327
MIRT617352	hsa-miR-3115	HITS-CLIP	23824327
MIRT617351	hsa-miR-7703	HITS-CLIP	23824327
MIRT638505	hsa-miR-1262	HITS-CLIP	23824327
MIRT638504	hsa-miR-4701-3p	HITS-CLIP	23824327
MIRT638503	hsa-miR-6736-5p	HITS-CLIP	23824327
MIRT617360	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT617359	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT617358	hsa-miR-4712-5p	HITS-CLIP	23824327
MIRT617357	hsa-miR-770-5p	HITS-CLIP	23824327
MIRT617356	hsa-miR-3925-3p	HITS-CLIP	23824327
MIRT617355	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT617354	hsa-miR-5186	HITS-CLIP	23824327
MIRT617353	hsa-miR-4252	HITS-CLIP	23824327
MIRT617352	hsa-miR-3115	HITS-CLIP	23824327
MIRT617351	hsa-miR-7703	HITS-CLIP	23824327
MIRT638505	hsa-miR-1262	HITS-CLIP	23824327
MIRT638504	hsa-miR-4701-3p	HITS-CLIP	23824327
MIRT638503	hsa-miR-6736-5p	HITS-CLIP	23824327
MIRT628572	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT628571	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT628570	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT628569	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT628568	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT628567	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT628566	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT628565	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT628564	hsa-miR-3973	HITS-CLIP	23824327
MIRT628563	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT628562	hsa-miR-520h	HITS-CLIP	23824327
MIRT628561	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT628560	hsa-miR-764	HITS-CLIP	23824327
MIRT628559	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT628558	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT628557	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT628556	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT535982	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT628555	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT628554	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT628553	hsa-miR-640	HITS-CLIP	23824327
MIRT628006	hsa-miR-6800-3p	HITS-CLIP	23824327
MIRT628005	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT628004	hsa-miR-10b-3p	HITS-CLIP	23824327
MIRT628003	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT628002	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT628001	hsa-miR-4330	HITS-CLIP	23824327
MIRT628000	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT627999	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT627998	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT627997	hsa-miR-891b	HITS-CLIP	23824327
MIRT627996	hsa-miR-4284	HITS-CLIP	23824327
MIRT617360	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT617359	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT617358	hsa-miR-4712-5p	HITS-CLIP	23824327
MIRT617357	hsa-miR-770-5p	HITS-CLIP	23824327
MIRT617356	hsa-miR-3925-3p	HITS-CLIP	23824327
MIRT617355	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT617354	hsa-miR-5186	HITS-CLIP	23824327
MIRT617353	hsa-miR-4252	HITS-CLIP	23824327
MIRT617352	hsa-miR-3115	HITS-CLIP	23824327
MIRT617351	hsa-miR-7703	HITS-CLIP	23824327
MIRT535982	hsa-miR-371a-5p	PAR-CLIP	22012620
MIRT535981	hsa-miR-372-5p	PAR-CLIP	22012620
MIRT535979	hsa-miR-4668-5p	PAR-CLIP	22012620
MIRT628572	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT628571	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT628570	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT628569	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT628568	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT628567	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT628566	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT628565	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT656330	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT656329	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT656328	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT656327	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT656326	hsa-miR-302e	HITS-CLIP	23824327
MIRT656325	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT656324	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT656323	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT656322	hsa-miR-520b	HITS-CLIP	23824327
MIRT656321	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT656320	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT656319	hsa-miR-520e	HITS-CLIP	23824327
MIRT628564	hsa-miR-3973	HITS-CLIP	23824327
MIRT628563	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT628562	hsa-miR-520h	HITS-CLIP	23824327
MIRT628561	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT628560	hsa-miR-764	HITS-CLIP	23824327
MIRT628559	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT628558	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT628557	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT628556	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT674106	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT674105	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT674104	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT535982	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT535981	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT628555	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT628554	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT628553	hsa-miR-640	HITS-CLIP	23824327
MIRT628561	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT628560	hsa-miR-764	HITS-CLIP	23824327
MIRT628559	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT628558	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT628557	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT628556	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT535982	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT669869	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT669868	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669867	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT628555	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT628554	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT669866	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT628553	hsa-miR-640	HITS-CLIP	23824327
MIRT617360	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT617358	hsa-miR-4712-5p	HITS-CLIP	23824327
MIRT617357	hsa-miR-770-5p	HITS-CLIP	23824327
MIRT617356	hsa-miR-3925-3p	HITS-CLIP	23824327
MIRT617355	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT617354	hsa-miR-5186	HITS-CLIP	23824327
MIRT617353	hsa-miR-4252	HITS-CLIP	23824327
MIRT617352	hsa-miR-3115	HITS-CLIP	23824327
MIRT617351	hsa-miR-7703	HITS-CLIP	23824327
MIRT638505	hsa-miR-1262	HITS-CLIP	23824327
MIRT638504	hsa-miR-4701-3p	HITS-CLIP	23824327
MIRT638503	hsa-miR-6736-5p	HITS-CLIP	23824327
MIRT628572	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT628571	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT628570	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT628569	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT628568	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT628567	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT628566	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT628565	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT656330	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT656329	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT656328	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT656327	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT656326	hsa-miR-302e	HITS-CLIP	23824327
MIRT656325	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT656324	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT656323	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT656322	hsa-miR-520b	HITS-CLIP	23824327
MIRT656321	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT656320	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT656319	hsa-miR-520e	HITS-CLIP	23824327
MIRT628564	hsa-miR-3973	HITS-CLIP	23824327
MIRT628563	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT628562	hsa-miR-520h	HITS-CLIP	23824327
MIRT628561	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT628560	hsa-miR-764	HITS-CLIP	23824327
MIRT628559	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT628558	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT628557	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT628556	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT535982	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT628555	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT628554	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT628553	hsa-miR-640	HITS-CLIP	23824327
MIRT617360	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT617359	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT617358	hsa-miR-4712-5p	HITS-CLIP	23824327
MIRT617357	hsa-miR-770-5p	HITS-CLIP	23824327
MIRT617356	hsa-miR-3925-3p	HITS-CLIP	23824327
MIRT617355	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT617354	hsa-miR-5186	HITS-CLIP	23824327
MIRT617353	hsa-miR-4252	HITS-CLIP	23824327
MIRT617352	hsa-miR-3115	HITS-CLIP	23824327
MIRT617351	hsa-miR-7703	HITS-CLIP	23824327
MIRT638505	hsa-miR-1262	HITS-CLIP	23824327
MIRT638504	hsa-miR-4701-3p	HITS-CLIP	23824327
MIRT638503	hsa-miR-6736-5p	HITS-CLIP	23824327
MIRT617360	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT617359	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT617358	hsa-miR-4712-5p	HITS-CLIP	23824327
MIRT617357	hsa-miR-770-5p	HITS-CLIP	23824327
MIRT617356	hsa-miR-3925-3p	HITS-CLIP	23824327
MIRT617355	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT617354	hsa-miR-5186	HITS-CLIP	23824327
MIRT617353	hsa-miR-4252	HITS-CLIP	23824327
MIRT617352	hsa-miR-3115	HITS-CLIP	23824327
MIRT617351	hsa-miR-7703	HITS-CLIP	23824327
MIRT638505	hsa-miR-1262	HITS-CLIP	23824327
MIRT638504	hsa-miR-4701-3p	HITS-CLIP	23824327
MIRT638503	hsa-miR-6736-5p	HITS-CLIP	23824327
MIRT628572	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT628571	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT628570	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT628569	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT628568	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT628567	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT628566	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT628565	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT628564	hsa-miR-3973	HITS-CLIP	23824327
MIRT628563	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT628562	hsa-miR-520h	HITS-CLIP	23824327
MIRT628561	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT628560	hsa-miR-764	HITS-CLIP	23824327
MIRT628559	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT628558	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT628557	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT628556	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT535982	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT628555	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT628554	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT628553	hsa-miR-640	HITS-CLIP	23824327
MIRT628006	hsa-miR-6800-3p	HITS-CLIP	23824327
MIRT628005	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT628004	hsa-miR-10b-3p	HITS-CLIP	23824327
MIRT628003	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT628002	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT628001	hsa-miR-4330	HITS-CLIP	23824327
MIRT628000	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT627999	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT627998	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT627997	hsa-miR-891b	HITS-CLIP	23824327
MIRT627996	hsa-miR-4284	HITS-CLIP	23824327
MIRT617360	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT617359	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT617358	hsa-miR-4712-5p	HITS-CLIP	23824327
MIRT617357	hsa-miR-770-5p	HITS-CLIP	23824327
MIRT617356	hsa-miR-3925-3p	HITS-CLIP	23824327
MIRT617355	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT617354	hsa-miR-5186	HITS-CLIP	23824327
MIRT617353	hsa-miR-4252	HITS-CLIP	23824327
MIRT617352	hsa-miR-3115	HITS-CLIP	23824327
MIRT617351	hsa-miR-7703	HITS-CLIP	23824327
MIRT535982	hsa-miR-371a-5p	PAR-CLIP	22012620
MIRT535981	hsa-miR-372-5p	PAR-CLIP	22012620
MIRT535979	hsa-miR-4668-5p	PAR-CLIP	22012620
MIRT1142859	hsa-miR-323-3p	CLIP-seq
MIRT1142860	hsa-miR-330-3p	CLIP-seq
MIRT1142861	hsa-miR-3941	CLIP-seq
MIRT1142862	hsa-miR-3942-3p	CLIP-seq
MIRT1142863	hsa-miR-4643	CLIP-seq
MIRT1142864	hsa-miR-4645-3p	CLIP-seq
MIRT1142865	hsa-miR-466	CLIP-seq
MIRT1142866	hsa-miR-4668-3p	CLIP-seq
MIRT1142867	hsa-miR-4672	CLIP-seq
MIRT1142868	hsa-miR-4789-3p	CLIP-seq
MIRT1142869	hsa-miR-4803	CLIP-seq
MIRT1142870	hsa-miR-802	CLIP-seq
MIRT2270385	hsa-miR-2392	CLIP-seq
MIRT2270386	hsa-miR-7	CLIP-seq

Show/Hide all(26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000086	Process	G2/M transition of mitotic cell cycle	TAS	12400006
GO:0004674	Function	Protein serine/threonine kinase activity	IBA	21873635
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	12400006, 15908796, 16216881, 17280616
GO:0004715	Function	Non-membrane spanning protein tyrosine kinase activity	IBA	21873635
GO:0004715	Function	Non-membrane spanning protein tyrosine kinase activity	IDA	16216881
GO:0005509	Function	Calcium ion binding	IDA	16216881
GO:0005515	Function	Protein binding	IPI	12400006, 15908796, 17280616
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005886	Component	Plasma membrane	IDA	21145462
GO:0005938	Component	Cell cortex	IDA	16159311
GO:0006468	Process	Protein phosphorylation	IBA	21873635
GO:0006915	Process	Apoptotic process	IDA	17280616
GO:0008283	Process	Cell population proliferation	IDA	17280616
GO:0008289	Function	Lipid binding	IEA
GO:0008631	Process	Intrinsic apoptotic signaling pathway in response to oxidative stress	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0018108	Process	Peptidyl-tyrosine phosphorylation	IEA
GO:0030097	Process	Hemopoiesis	ISS
GO:0035556	Process	Intracellular signal transduction	IBA	21873635
GO:0043065	Process	Positive regulation of apoptotic process	ISS
GO:0046777	Process	Protein autophosphorylation	IDA	16216881
GO:0061351	Process	Neural precursor cell proliferation	ISS
GO:0106310	Function	Protein serine kinase activity	IEA
GO:0106311	Function	Protein threonine kinase activity	IEA

MIM	HGNC	e!Ensembl
607025	16870	ENSG00000165304

Protein

UniProt ID

Q14680

Protein name

Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)

Protein function

Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622

PDB

4BKY , 4BKZ , 4BL1 , 4D2P , 4D2T , 4D2V , 4D2W , 4IXP , 4UMP , 4UMQ , 4UMR , 4UMT , 4UMU , 5IH8 , 5IH9 , 5IHA , 5IHC , 5K00 , 5M5A , 5MAF , 5MAG , 5MAH , 5MAI , 5TVT , 5TWL , 5TWU , 5TWY , 5TWZ , 5TX3 , 6GVX , 6VXR , 9F31

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	11 → 263	Protein kinase domain	Domain
PF02149	KA1	607 → 651	Kinase associated domain 1	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in placenta, kidney, thymus, testis, ovary and intestine. {ECO:0000269|PubMed:8724849}.

Sequence

MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEA
LKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAV
AYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELI
QGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLL
QQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQT
MEDLISLWQYDHLTATYLLLLAKKARGKPVRLRLSSFSCGQASATPFTDIKSNNWSLEDV
TASDKNYVAGLIDYDWCEDDLSTGAATPRTSQFTKYWTESNGVESKSLTPALCRTPANKL
KNKENVYTPKSAVKNEEYFMFPEPKTPVNKNQHKREILTTPNRYTTPSKARNQCLKETPI
KIPVNSTGTDKLMTGVISPERRCRSVELDLNQAHMEETPKRKGAKVFGSLERGLDKVITV
LTRSKRKGSARDGPRRLKLHYNVTTTRLVNPDQLLNEIMSILPKKHVDFVQKGYTLKCQT
QSDFGKVTMQFELEVCQLQKPDVVGIRRQRLKGDAWVYKRLVEDILSSCKV

Sequence length

651

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Evidence	Source
Unknown
Colorectal Cancer	Colorectal Cancer	In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1.	GWAS, CBGDA
Alzheimer disease	Alzheimer disease		GWAS

Show/Hide Text Mining Associations (52)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma	Associate	26683690, 28640357
Adenocarcinoma of Lung	Associate	23357462, 34304612
Adenocarcinoma of Lung	Stimulate	38376289
Adrenal Gland Neoplasms	Associate	29790920
Adrenocortical Carcinoma	Associate	29790920
Ascites	Associate	33078598
Breast Neoplasms	Stimulate	17280616
Breast Neoplasms	Associate	19671159, 25756514, 28214016, 28337968, 28926338, 30732163, 31352007, 35749404, 36096037, 36757135, 36930083, 37713876
Carcinogenesis	Associate	17280616, 21338529, 35440604, 37949877
Carcinoma Ductal	Associate	35749404
Carcinoma Hepatocellular	Associate	29192136, 32722976, 33102593, 33879119, 35511171, 37008632, 37949877, 39596041
Carcinoma Hepatocellular	Stimulate	38376289
Carcinoma Intraductal Noninfiltrating	Associate	35880695
Carcinoma Ovarian Epithelial	Associate	28214016
Carcinoma Renal Cell	Associate	28260099, 35896362, 36793506, 37340189, 38376289
Carcinoma Renal Cell	Stimulate	31813279
Cell Transformation Neoplastic	Associate	31352007
Colorectal Neoplasms	Associate	31358735, 35440604
DNA Repair Deficiency Disorders	Associate	36757135
GATA2 Deficiency	Associate	31434700
Glioblastoma	Stimulate	21691733
Glioblastoma	Associate	31352007, 38167429
Glioma	Associate	31434700
Hepatitis B	Associate	25756514, 33102593
Hypoxia Brain	Associate	29790920
Inflammation	Associate	37589542
Kidney Neoplasms	Associate	26933922
Leukemia	Associate	25365263, 26308964
Leukemia Myeloid Acute	Associate	25365263
Lymphatic Metastasis	Stimulate	33962400
Melanoma	Associate	17611626, 29212029
Mouth Neoplasms	Associate	37589542
Multiple Myeloma	Associate	31289205
Necrosis	Associate	37589542
Neoplasm Metastasis	Associate	27574806
Neoplasm Metastasis	Stimulate	38376289
Neoplasms	Stimulate	21338529, 25365263, 26701722, 28235006
Neoplasms	Associate	26431963, 26468983, 26871945, 26933922, 27574806, 28337968, 28926338, 29192136, 29790920, 30334367, 31352007, 31896573, 33078598, 33235818, 35511171 View all (8 more)
Neoplasms	Inhibit	33962400
Oligodendroglioma	Associate	26468983
Osteoarthritis	Associate	35992546
Ovarian Neoplasms	Associate	28214016, 33078598, 33235818
Pancreatic Neoplasms	Associate	31412643
Prostatic Neoplasms	Associate	26501111, 37888771
Small Cell Lung Carcinoma	Associate	26871945
Squamous Cell Carcinoma of Head and Neck	Associate	33962400
Stomach Neoplasms	Associate	26701722, 27920471, 38376289
Triple Negative Breast Neoplasms	Associate	28235006, 35749404, 36998242
Urinary Bladder Neoplasms	Associate	36181054
Uterine Cervical Dysplasia	Stimulate	30334367
Uterine Cervical Dysplasia	Associate	35008799
Uterine Cervical Neoplasms	Associate	21338529, 30334367, 33235818, 33829064

MELK (maternal embryonic leucine zipper kinase)