ARHGAP11A (Rho GTPase activating protein 11A)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9824 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Rho GTPase activating protein 11A |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ARHGAP11A |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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GAP (1-12) |
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Chromosome
Chromosome number
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15 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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15q13.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q6P4F7 | ||||||||||
| Protein name | Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A) | ||||||||||
| Protein function | GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | ||||||||||
| PDB | 3EAP | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1023 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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