BCLAF1 (BCL2 associated transcription factor 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 9774 |
| Gene name | BCL2 associated transcription factor 1 |
| Gene symbol | BCLAF1 |
| Synonyms (NCBI Gene) |
BTFbK211L9.1
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| Chromosome | 6 |
| Chromosome location | 6q23.3 |
| Summary | This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-lik |
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miRNA
miRNA information provided by mirtarbase database.
405
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9NYF8 | ||||||||||
| Protein name | Bcl-2-associated transcription factor 1 (Btf) (BCLAF1 and THRAP3 family member 1) | ||||||||||
| Protein function | Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. | ||||||||||
| PDB | 7RJN , 7RJR | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. | ||||||||||
| Sequence |
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| Sequence length | 920 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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