ZFYVE16 (zinc finger FYVE-type containing 16)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
9765 |
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Zinc finger FYVE-type containing 16 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
ZFYVE16 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
PPP1R69 |
Chromosome
Chromosome number
|
5 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
5q14.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor |
SNPs
SNP information provided by dbSNP.
|
|||||||||
|
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
Protein | ||||||||||||||||
UniProt ID | Q7Z3T8 | |||||||||||||||
Protein name | Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein) | |||||||||||||||
Protein function | May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes. | |||||||||||||||
PDB | 3T7L , 5MK0 | |||||||||||||||
Family and domains |
Pfam
|
|||||||||||||||
Tissue specificity | TISSUE SPECIFICITY: Widely expressed. Highly expressed in kidney, placenta and lung. Expressed at intermediate level in heart, brain, skeletal muscle, spleen and liver. Weakly expressed in colon, thymus and peripheral blood lymphocytes. {ECO:0000269|PubMe | |||||||||||||||
Sequence |
|
|||||||||||||||
Sequence length | 1539 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||||||||
|
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
|
||||||||||||||||
|
||||||||||||||||
|