SLK (STE20 like kinase)

Gene

• Entrez ID: 9748
• Gene name: STE20 like kinase
• Gene symbol: SLK
• Synonyms (NCBI Gene): LOSK, STK2, bA16H23.1, se20-9
• Chromosome: 10
• Chromosome location: 10q24.33-q25.1

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs1589547463	C>T	Likely-pathogenic	Coding sequence variant, stop gained

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT031072	hsa-miR-21-5p	Microarray	20371350
MIRT031072	hsa-miR-21-5p	Microarray	18591254
MIRT051774	hsa-let-7c-5p	CLASH	23622248
MIRT042026	hsa-miR-484	CLASH	23622248
MIRT040336	hsa-miR-615-3p	CLASH	23622248
MIRT439592	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT439590	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT439592	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT726498	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT726497	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT726496	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT726495	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT439590	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT1369830	hsa-miR-101	CLIP-seq
MIRT1369831	hsa-miR-106a	CLIP-seq
MIRT1369832	hsa-miR-106b	CLIP-seq
MIRT1369833	hsa-miR-1207-5p	CLIP-seq
MIRT1369834	hsa-miR-1245	CLIP-seq
MIRT1369835	hsa-miR-1265	CLIP-seq
MIRT1369836	hsa-miR-1305	CLIP-seq
MIRT1369837	hsa-miR-132	CLIP-seq
MIRT1369838	hsa-miR-144	CLIP-seq
MIRT1369839	hsa-miR-17	CLIP-seq
MIRT1369840	hsa-miR-181a	CLIP-seq
MIRT1369841	hsa-miR-181b	CLIP-seq
MIRT1369842	hsa-miR-181c	CLIP-seq
MIRT1369843	hsa-miR-181d	CLIP-seq
MIRT1369844	hsa-miR-194	CLIP-seq
MIRT1369845	hsa-miR-200b	CLIP-seq
MIRT1369846	hsa-miR-200c	CLIP-seq
MIRT1369847	hsa-miR-20a	CLIP-seq
MIRT1369848	hsa-miR-20b	CLIP-seq
MIRT1369849	hsa-miR-212	CLIP-seq
MIRT1369850	hsa-miR-221	CLIP-seq
MIRT1369851	hsa-miR-222	CLIP-seq
MIRT1369852	hsa-miR-2276	CLIP-seq
MIRT1369853	hsa-miR-2392	CLIP-seq
MIRT1369854	hsa-miR-29a	CLIP-seq
MIRT1369855	hsa-miR-29b	CLIP-seq
MIRT1369856	hsa-miR-29c	CLIP-seq
MIRT1369857	hsa-miR-302a	CLIP-seq
MIRT1369858	hsa-miR-302b	CLIP-seq
MIRT1369859	hsa-miR-302c	CLIP-seq
MIRT1369860	hsa-miR-302d	CLIP-seq
MIRT1369861	hsa-miR-302e	CLIP-seq
MIRT1369862	hsa-miR-3124-3p	CLIP-seq
MIRT1369863	hsa-miR-3129-3p	CLIP-seq
MIRT1369864	hsa-miR-3149	CLIP-seq
MIRT1369865	hsa-miR-3161	CLIP-seq
MIRT1369866	hsa-miR-3163	CLIP-seq
MIRT1369867	hsa-miR-3171	CLIP-seq
MIRT1369868	hsa-miR-3187-3p	CLIP-seq
MIRT1369869	hsa-miR-340	CLIP-seq
MIRT1369870	hsa-miR-34b	CLIP-seq
MIRT1369871	hsa-miR-3606	CLIP-seq
MIRT1369872	hsa-miR-3607-5p	CLIP-seq
MIRT1369873	hsa-miR-3622a-5p	CLIP-seq
MIRT1369874	hsa-miR-3647-3p	CLIP-seq
MIRT1369875	hsa-miR-365	CLIP-seq
MIRT1369876	hsa-miR-3653	CLIP-seq
MIRT1369877	hsa-miR-3658	CLIP-seq
MIRT1369878	hsa-miR-3671	CLIP-seq
MIRT1369879	hsa-miR-3689a-5p	CLIP-seq
MIRT1369880	hsa-miR-3689b	CLIP-seq
MIRT1369881	hsa-miR-3689e	CLIP-seq
MIRT1369882	hsa-miR-3689f	CLIP-seq
MIRT1369883	hsa-miR-372	CLIP-seq
MIRT1369884	hsa-miR-373	CLIP-seq
MIRT1369885	hsa-miR-374c	CLIP-seq
MIRT1369886	hsa-miR-377	CLIP-seq
MIRT1369887	hsa-miR-382	CLIP-seq
MIRT1369888	hsa-miR-410	CLIP-seq
MIRT1369889	hsa-miR-4262	CLIP-seq
MIRT1369890	hsa-miR-4275	CLIP-seq
MIRT1369891	hsa-miR-4282	CLIP-seq
MIRT1369892	hsa-miR-429	CLIP-seq
MIRT1369893	hsa-miR-4291	CLIP-seq
MIRT1369894	hsa-miR-4310	CLIP-seq
MIRT1369895	hsa-miR-4328	CLIP-seq
MIRT1369896	hsa-miR-4423-3p	CLIP-seq
MIRT1369897	hsa-miR-4435	CLIP-seq
MIRT1369898	hsa-miR-4477a	CLIP-seq
MIRT1369899	hsa-miR-4514	CLIP-seq
MIRT1369900	hsa-miR-4539	CLIP-seq
MIRT1369901	hsa-miR-4643	CLIP-seq
MIRT1369902	hsa-miR-4666-5p	CLIP-seq
MIRT1369903	hsa-miR-4670-3p	CLIP-seq
MIRT1369904	hsa-miR-4692	CLIP-seq
MIRT1369905	hsa-miR-4696	CLIP-seq
MIRT1369906	hsa-miR-4699-5p	CLIP-seq
MIRT1369907	hsa-miR-4701-5p	CLIP-seq
MIRT1369908	hsa-miR-4719	CLIP-seq
MIRT1369909	hsa-miR-4736	CLIP-seq
MIRT1369910	hsa-miR-4762-3p	CLIP-seq
MIRT1369911	hsa-miR-4762-5p	CLIP-seq
MIRT1369912	hsa-miR-4763-3p	CLIP-seq
MIRT1369913	hsa-miR-4775	CLIP-seq
MIRT1369914	hsa-miR-4778-5p	CLIP-seq
MIRT1369915	hsa-miR-4799-5p	CLIP-seq
MIRT1369916	hsa-miR-495	CLIP-seq
MIRT1369917	hsa-miR-513a-3p	CLIP-seq
MIRT1369918	hsa-miR-513b	CLIP-seq
MIRT1369919	hsa-miR-519d	CLIP-seq
MIRT1369920	hsa-miR-520a-3p	CLIP-seq
MIRT1369921	hsa-miR-520b	CLIP-seq
MIRT1369922	hsa-miR-520c-3p	CLIP-seq
MIRT1369923	hsa-miR-520d-3p	CLIP-seq
MIRT1369924	hsa-miR-520e	CLIP-seq
MIRT1369925	hsa-miR-548l	CLIP-seq
MIRT1369926	hsa-miR-548n	CLIP-seq
MIRT1369927	hsa-miR-548s	CLIP-seq
MIRT1369928	hsa-miR-548v	CLIP-seq
MIRT1369929	hsa-miR-553	CLIP-seq
MIRT1369930	hsa-miR-561	CLIP-seq
MIRT1369931	hsa-miR-568	CLIP-seq
MIRT1369932	hsa-miR-583	CLIP-seq
MIRT1369933	hsa-miR-586	CLIP-seq
MIRT1369934	hsa-miR-588	CLIP-seq
MIRT1369935	hsa-miR-595	CLIP-seq
MIRT1369936	hsa-miR-607	CLIP-seq
MIRT1369937	hsa-miR-624	CLIP-seq
MIRT1369938	hsa-miR-630	CLIP-seq
MIRT1369939	hsa-miR-651	CLIP-seq
MIRT1369940	hsa-miR-655	CLIP-seq
MIRT1369941	hsa-miR-802	CLIP-seq
MIRT1369942	hsa-miR-921	CLIP-seq
MIRT1369943	hsa-miR-93	CLIP-seq
MIRT1369944	hsa-miR-944	CLIP-seq
MIRT2109785	hsa-miR-1226	CLIP-seq
MIRT2109786	hsa-miR-1273g	CLIP-seq
MIRT2109787	hsa-miR-186	CLIP-seq
MIRT2109788	hsa-miR-197	CLIP-seq
MIRT1369845	hsa-miR-200b	CLIP-seq
MIRT1369846	hsa-miR-200c	CLIP-seq
MIRT2109789	hsa-miR-203	CLIP-seq
MIRT1369862	hsa-miR-3124-3p	CLIP-seq
MIRT2109790	hsa-miR-3133	CLIP-seq
MIRT1369870	hsa-miR-34b	CLIP-seq
MIRT2109791	hsa-miR-371b-5p	CLIP-seq
MIRT2109792	hsa-miR-3941	CLIP-seq
MIRT2109793	hsa-miR-4263	CLIP-seq
MIRT2109794	hsa-miR-4274	CLIP-seq
MIRT1369892	hsa-miR-429	CLIP-seq
MIRT1369893	hsa-miR-4291	CLIP-seq
MIRT1369895	hsa-miR-4328	CLIP-seq
MIRT2109795	hsa-miR-4420	CLIP-seq
MIRT2109796	hsa-miR-4462	CLIP-seq
MIRT2109797	hsa-miR-4475	CLIP-seq
MIRT2109798	hsa-miR-4509	CLIP-seq
MIRT2109799	hsa-miR-4519	CLIP-seq
MIRT1369902	hsa-miR-4666-5p	CLIP-seq
MIRT2109800	hsa-miR-4709-5p	CLIP-seq
MIRT2109801	hsa-miR-4733-3p	CLIP-seq
MIRT2109802	hsa-miR-4744	CLIP-seq
MIRT1369915	hsa-miR-4799-5p	CLIP-seq
MIRT2109803	hsa-miR-5096	CLIP-seq
MIRT1369917	hsa-miR-513a-3p	CLIP-seq
MIRT2109804	hsa-miR-515-5p	CLIP-seq
MIRT1369926	hsa-miR-548n	CLIP-seq
MIRT1369928	hsa-miR-548v	CLIP-seq
MIRT2109805	hsa-miR-563	CLIP-seq
MIRT1369937	hsa-miR-624	CLIP-seq
MIRT1369830	hsa-miR-101	CLIP-seq
MIRT1369831	hsa-miR-106a	CLIP-seq
MIRT1369832	hsa-miR-106b	CLIP-seq
MIRT2109785	hsa-miR-1226	CLIP-seq
MIRT1369834	hsa-miR-1245	CLIP-seq
MIRT2109786	hsa-miR-1273g	CLIP-seq
MIRT2333203	hsa-miR-1276	CLIP-seq
MIRT1369838	hsa-miR-144	CLIP-seq
MIRT1369839	hsa-miR-17	CLIP-seq
MIRT1369840	hsa-miR-181a	CLIP-seq
MIRT1369841	hsa-miR-181b	CLIP-seq
MIRT1369842	hsa-miR-181c	CLIP-seq
MIRT1369843	hsa-miR-181d	CLIP-seq
MIRT2109787	hsa-miR-186	CLIP-seq
MIRT1369844	hsa-miR-194	CLIP-seq
MIRT2109788	hsa-miR-197	CLIP-seq
MIRT1369845	hsa-miR-200b	CLIP-seq
MIRT1369846	hsa-miR-200c	CLIP-seq
MIRT2109789	hsa-miR-203	CLIP-seq
MIRT2333204	hsa-miR-204	CLIP-seq
MIRT1369847	hsa-miR-20a	CLIP-seq
MIRT1369848	hsa-miR-20b	CLIP-seq
MIRT2333205	hsa-miR-211	CLIP-seq
MIRT1369850	hsa-miR-221	CLIP-seq
MIRT1369851	hsa-miR-222	CLIP-seq
MIRT2333206	hsa-miR-224	CLIP-seq
MIRT1369852	hsa-miR-2276	CLIP-seq
MIRT2333207	hsa-miR-300	CLIP-seq
MIRT1369857	hsa-miR-302a	CLIP-seq
MIRT1369858	hsa-miR-302b	CLIP-seq
MIRT1369859	hsa-miR-302c	CLIP-seq
MIRT1369860	hsa-miR-302d	CLIP-seq
MIRT1369861	hsa-miR-302e	CLIP-seq
MIRT2333208	hsa-miR-3120-5p	CLIP-seq
MIRT2109790	hsa-miR-3133	CLIP-seq
MIRT2333209	hsa-miR-3140-5p	CLIP-seq
MIRT1369864	hsa-miR-3149	CLIP-seq
MIRT1369865	hsa-miR-3161	CLIP-seq
MIRT1369867	hsa-miR-3171	CLIP-seq
MIRT2333210	hsa-miR-329	CLIP-seq
MIRT1369871	hsa-miR-3606	CLIP-seq
MIRT1369872	hsa-miR-3607-5p	CLIP-seq
MIRT2333211	hsa-miR-362-3p	CLIP-seq
MIRT1369874	hsa-miR-3647-3p	CLIP-seq
MIRT1369879	hsa-miR-3689a-5p	CLIP-seq
MIRT1369880	hsa-miR-3689b	CLIP-seq
MIRT1369881	hsa-miR-3689e	CLIP-seq
MIRT1369882	hsa-miR-3689f	CLIP-seq
MIRT1369883	hsa-miR-372	CLIP-seq
MIRT1369884	hsa-miR-373	CLIP-seq
MIRT1369885	hsa-miR-374c	CLIP-seq
MIRT2333212	hsa-miR-381	CLIP-seq
MIRT2109792	hsa-miR-3941	CLIP-seq
MIRT1369888	hsa-miR-410	CLIP-seq
MIRT1369889	hsa-miR-4262	CLIP-seq
MIRT2109793	hsa-miR-4263	CLIP-seq
MIRT2109794	hsa-miR-4274	CLIP-seq
MIRT1369892	hsa-miR-429	CLIP-seq
MIRT1369894	hsa-miR-4310	CLIP-seq
MIRT1369895	hsa-miR-4328	CLIP-seq
MIRT2333213	hsa-miR-4427	CLIP-seq
MIRT2333214	hsa-miR-4446-5p	CLIP-seq
MIRT2109796	hsa-miR-4462	CLIP-seq
MIRT2109797	hsa-miR-4475	CLIP-seq
MIRT1369898	hsa-miR-4477a	CLIP-seq
MIRT2109798	hsa-miR-4509	CLIP-seq
MIRT2109799	hsa-miR-4519	CLIP-seq
MIRT2333215	hsa-miR-466	CLIP-seq
MIRT2333216	hsa-miR-4666-3p	CLIP-seq
MIRT2333217	hsa-miR-4672	CLIP-seq
MIRT1369905	hsa-miR-4696	CLIP-seq
MIRT2109800	hsa-miR-4709-5p	CLIP-seq
MIRT2109801	hsa-miR-4733-3p	CLIP-seq
MIRT2109802	hsa-miR-4744	CLIP-seq
MIRT2333218	hsa-miR-4755-5p	CLIP-seq
MIRT1369911	hsa-miR-4762-5p	CLIP-seq
MIRT2333219	hsa-miR-4766-5p	CLIP-seq
MIRT2333220	hsa-miR-4776-3p	CLIP-seq
MIRT2333221	hsa-miR-4793-5p	CLIP-seq
MIRT2109803	hsa-miR-5096	CLIP-seq
MIRT1369917	hsa-miR-513a-3p	CLIP-seq
MIRT2109804	hsa-miR-515-5p	CLIP-seq
MIRT1369919	hsa-miR-519d	CLIP-seq
MIRT1369920	hsa-miR-520a-3p	CLIP-seq
MIRT1369921	hsa-miR-520b	CLIP-seq
MIRT1369922	hsa-miR-520c-3p	CLIP-seq
MIRT1369923	hsa-miR-520d-3p	CLIP-seq
MIRT2333222	hsa-miR-520d-5p	CLIP-seq
MIRT1369924	hsa-miR-520e	CLIP-seq
MIRT2333223	hsa-miR-524-5p	CLIP-seq
MIRT1369928	hsa-miR-548v	CLIP-seq
MIRT2109805	hsa-miR-563	CLIP-seq
MIRT1369931	hsa-miR-568	CLIP-seq
MIRT1369935	hsa-miR-595	CLIP-seq
MIRT2333224	hsa-miR-603	CLIP-seq
MIRT2333225	hsa-miR-623	CLIP-seq
MIRT2333226	hsa-miR-634	CLIP-seq
MIRT1369940	hsa-miR-655	CLIP-seq
MIRT1369941	hsa-miR-802	CLIP-seq
MIRT1369942	hsa-miR-921	CLIP-seq
MIRT1369943	hsa-miR-93	CLIP-seq
MIRT2109786	hsa-miR-1273g	CLIP-seq
MIRT2394846	hsa-miR-145	CLIP-seq
MIRT2109789	hsa-miR-203	CLIP-seq
MIRT2333208	hsa-miR-3120-5p	CLIP-seq
MIRT2394847	hsa-miR-3180-5p	CLIP-seq
MIRT2109793	hsa-miR-4263	CLIP-seq
MIRT2109796	hsa-miR-4462	CLIP-seq
MIRT2109797	hsa-miR-4475	CLIP-seq
MIRT2394848	hsa-miR-450b-5p	CLIP-seq
MIRT2333220	hsa-miR-4776-3p	CLIP-seq
MIRT2109805	hsa-miR-563	CLIP-seq
MIRT1369830	hsa-miR-101	CLIP-seq
MIRT2433313	hsa-miR-1260	CLIP-seq
MIRT2433314	hsa-miR-1260b	CLIP-seq
MIRT1369838	hsa-miR-144	CLIP-seq
MIRT1369840	hsa-miR-181a	CLIP-seq
MIRT1369841	hsa-miR-181b	CLIP-seq
MIRT1369842	hsa-miR-181c	CLIP-seq
MIRT1369843	hsa-miR-181d	CLIP-seq
MIRT2433315	hsa-miR-188-3p	CLIP-seq
MIRT2433316	hsa-miR-3156-3p	CLIP-seq
MIRT1369865	hsa-miR-3161	CLIP-seq
MIRT1369872	hsa-miR-3607-5p	CLIP-seq
MIRT1369879	hsa-miR-3689a-5p	CLIP-seq
MIRT1369880	hsa-miR-3689b	CLIP-seq
MIRT1369881	hsa-miR-3689e	CLIP-seq
MIRT1369882	hsa-miR-3689f	CLIP-seq
MIRT2433317	hsa-miR-4255	CLIP-seq
MIRT1369889	hsa-miR-4262	CLIP-seq
MIRT2433318	hsa-miR-4517	CLIP-seq
MIRT1369917	hsa-miR-513a-3p	CLIP-seq
MIRT1369935	hsa-miR-595	CLIP-seq
MIRT1369941	hsa-miR-802	CLIP-seq
MIRT1369831	hsa-miR-106a	CLIP-seq
MIRT1369832	hsa-miR-106b	CLIP-seq
MIRT1369836	hsa-miR-1305	CLIP-seq
MIRT1369839	hsa-miR-17	CLIP-seq
MIRT1369847	hsa-miR-20a	CLIP-seq
MIRT1369848	hsa-miR-20b	CLIP-seq
MIRT1369850	hsa-miR-221	CLIP-seq
MIRT1369851	hsa-miR-222	CLIP-seq
MIRT1369852	hsa-miR-2276	CLIP-seq
MIRT1369857	hsa-miR-302a	CLIP-seq
MIRT1369858	hsa-miR-302b	CLIP-seq
MIRT1369859	hsa-miR-302c	CLIP-seq
MIRT1369860	hsa-miR-302d	CLIP-seq
MIRT1369861	hsa-miR-302e	CLIP-seq
MIRT1369878	hsa-miR-3671	CLIP-seq
MIRT1369883	hsa-miR-372	CLIP-seq
MIRT1369884	hsa-miR-373	CLIP-seq
MIRT1369893	hsa-miR-4291	CLIP-seq
MIRT1369894	hsa-miR-4310	CLIP-seq
MIRT1369905	hsa-miR-4696	CLIP-seq
MIRT1369919	hsa-miR-519d	CLIP-seq
MIRT1369920	hsa-miR-520a-3p	CLIP-seq
MIRT1369921	hsa-miR-520b	CLIP-seq
MIRT1369922	hsa-miR-520c-3p	CLIP-seq
MIRT1369923	hsa-miR-520d-3p	CLIP-seq
MIRT1369924	hsa-miR-520e	CLIP-seq
MIRT1369928	hsa-miR-548v	CLIP-seq
MIRT1369930	hsa-miR-561	CLIP-seq
MIRT1369936	hsa-miR-607	CLIP-seq
MIRT1369937	hsa-miR-624	CLIP-seq
MIRT1369943	hsa-miR-93	CLIP-seq
MIRT2627411	hsa-miR-103b	CLIP-seq
MIRT1369831	hsa-miR-106a	CLIP-seq
MIRT1369832	hsa-miR-106b	CLIP-seq
MIRT2109785	hsa-miR-1226	CLIP-seq
MIRT2433313	hsa-miR-1260	CLIP-seq
MIRT2433314	hsa-miR-1260b	CLIP-seq
MIRT2109786	hsa-miR-1273g	CLIP-seq
MIRT1369836	hsa-miR-1305	CLIP-seq
MIRT1369839	hsa-miR-17	CLIP-seq
MIRT2627412	hsa-miR-185	CLIP-seq
MIRT2433315	hsa-miR-188-3p	CLIP-seq
MIRT2109788	hsa-miR-197	CLIP-seq
MIRT2109789	hsa-miR-203	CLIP-seq
MIRT2627413	hsa-miR-2052	CLIP-seq
MIRT1369847	hsa-miR-20a	CLIP-seq
MIRT1369848	hsa-miR-20b	CLIP-seq
MIRT1369850	hsa-miR-221	CLIP-seq
MIRT1369851	hsa-miR-222	CLIP-seq
MIRT1369852	hsa-miR-2276	CLIP-seq
MIRT1369854	hsa-miR-29a	CLIP-seq
MIRT1369855	hsa-miR-29b	CLIP-seq
MIRT1369856	hsa-miR-29c	CLIP-seq
MIRT1369857	hsa-miR-302a	CLIP-seq
MIRT1369858	hsa-miR-302b	CLIP-seq
MIRT1369859	hsa-miR-302c	CLIP-seq
MIRT1369860	hsa-miR-302d	CLIP-seq
MIRT1369861	hsa-miR-302e	CLIP-seq
MIRT2627414	hsa-miR-3119	CLIP-seq
MIRT2627415	hsa-miR-3155	CLIP-seq
MIRT2627416	hsa-miR-3155b	CLIP-seq
MIRT2433316	hsa-miR-3156-3p	CLIP-seq
MIRT2627417	hsa-miR-3160-3p	CLIP-seq
MIRT2333210	hsa-miR-329	CLIP-seq
MIRT2627418	hsa-miR-338-5p	CLIP-seq
MIRT1369870	hsa-miR-34b	CLIP-seq
MIRT2627419	hsa-miR-3591-5p	CLIP-seq
MIRT1369873	hsa-miR-3622a-5p	CLIP-seq
MIRT2333211	hsa-miR-362-3p	CLIP-seq
MIRT1369874	hsa-miR-3647-3p	CLIP-seq
MIRT1369876	hsa-miR-3653	CLIP-seq
MIRT1369877	hsa-miR-3658	CLIP-seq
MIRT1369878	hsa-miR-3671	CLIP-seq
MIRT2109791	hsa-miR-371b-5p	CLIP-seq
MIRT1369883	hsa-miR-372	CLIP-seq
MIRT1369884	hsa-miR-373	CLIP-seq
MIRT2109792	hsa-miR-3941	CLIP-seq
MIRT2627420	hsa-miR-421	CLIP-seq
MIRT2433317	hsa-miR-4255	CLIP-seq
MIRT2109793	hsa-miR-4263	CLIP-seq
MIRT2627421	hsa-miR-4267	CLIP-seq
MIRT1369890	hsa-miR-4275	CLIP-seq
MIRT1369893	hsa-miR-4291	CLIP-seq
MIRT2627422	hsa-miR-4301	CLIP-seq
MIRT2627423	hsa-miR-4302	CLIP-seq
MIRT2627424	hsa-miR-4306	CLIP-seq
MIRT1369894	hsa-miR-4310	CLIP-seq
MIRT2109795	hsa-miR-4420	CLIP-seq
MIRT1369896	hsa-miR-4423-3p	CLIP-seq
MIRT2627425	hsa-miR-4426	CLIP-seq
MIRT2333214	hsa-miR-4446-5p	CLIP-seq
MIRT2109796	hsa-miR-4462	CLIP-seq
MIRT2109797	hsa-miR-4475	CLIP-seq
MIRT2627426	hsa-miR-4484	CLIP-seq
MIRT2433318	hsa-miR-4517	CLIP-seq
MIRT2627427	hsa-miR-4534	CLIP-seq
MIRT2627428	hsa-miR-4644	CLIP-seq
MIRT2627429	hsa-miR-4647	CLIP-seq
MIRT2333215	hsa-miR-466	CLIP-seq
MIRT2627430	hsa-miR-4662b	CLIP-seq
MIRT2333217	hsa-miR-4672	CLIP-seq
MIRT2627431	hsa-miR-4678	CLIP-seq
MIRT1369905	hsa-miR-4696	CLIP-seq
MIRT2109800	hsa-miR-4709-5p	CLIP-seq
MIRT2627432	hsa-miR-4712-3p	CLIP-seq
MIRT2627433	hsa-miR-4729	CLIP-seq
MIRT2109801	hsa-miR-4733-3p	CLIP-seq
MIRT2627434	hsa-miR-4733-5p	CLIP-seq
MIRT2627435	hsa-miR-4753-3p	CLIP-seq
MIRT1369911	hsa-miR-4762-5p	CLIP-seq
MIRT2627436	hsa-miR-4768-5p	CLIP-seq
MIRT1369913	hsa-miR-4775	CLIP-seq
MIRT2627437	hsa-miR-4795-3p	CLIP-seq
MIRT2627438	hsa-miR-4797-5p	CLIP-seq
MIRT1369915	hsa-miR-4799-5p	CLIP-seq
MIRT2627439	hsa-miR-487a	CLIP-seq
MIRT2627440	hsa-miR-505	CLIP-seq
MIRT2109803	hsa-miR-5096	CLIP-seq
MIRT1369917	hsa-miR-513a-3p	CLIP-seq
MIRT2627441	hsa-miR-514	CLIP-seq
MIRT2627442	hsa-miR-514b-3p	CLIP-seq
MIRT1369919	hsa-miR-519d	CLIP-seq
MIRT1369920	hsa-miR-520a-3p	CLIP-seq
MIRT1369921	hsa-miR-520b	CLIP-seq
MIRT1369922	hsa-miR-520c-3p	CLIP-seq
MIRT1369923	hsa-miR-520d-3p	CLIP-seq
MIRT1369924	hsa-miR-520e	CLIP-seq
MIRT2627443	hsa-miR-539	CLIP-seq
MIRT2627444	hsa-miR-548an	CLIP-seq
MIRT1369926	hsa-miR-548n	CLIP-seq
MIRT1369928	hsa-miR-548v	CLIP-seq
MIRT1369930	hsa-miR-561	CLIP-seq
MIRT2109805	hsa-miR-563	CLIP-seq
MIRT2627445	hsa-miR-576-5p	CLIP-seq
MIRT1369932	hsa-miR-583	CLIP-seq
MIRT2627446	hsa-miR-590-3p	CLIP-seq
MIRT2333224	hsa-miR-603	CLIP-seq
MIRT1369936	hsa-miR-607	CLIP-seq
MIRT2627447	hsa-miR-616	CLIP-seq
MIRT1369937	hsa-miR-624	CLIP-seq
MIRT2333226	hsa-miR-634	CLIP-seq
MIRT2627448	hsa-miR-640	CLIP-seq
MIRT2627449	hsa-miR-888	CLIP-seq
MIRT1369943	hsa-miR-93	CLIP-seq
MIRT1369944	hsa-miR-944	CLIP-seq
MIRT1369831	hsa-miR-106a	CLIP-seq
MIRT1369832	hsa-miR-106b	CLIP-seq
MIRT2109785	hsa-miR-1226	CLIP-seq
MIRT2433313	hsa-miR-1260	CLIP-seq
MIRT2433314	hsa-miR-1260b	CLIP-seq
MIRT2691345	hsa-miR-1263	CLIP-seq
MIRT2109786	hsa-miR-1273g	CLIP-seq
MIRT1369836	hsa-miR-1305	CLIP-seq
MIRT1369839	hsa-miR-17	CLIP-seq
MIRT2627412	hsa-miR-185	CLIP-seq
MIRT2433315	hsa-miR-188-3p	CLIP-seq
MIRT2109789	hsa-miR-203	CLIP-seq
MIRT2627413	hsa-miR-2052	CLIP-seq
MIRT1369847	hsa-miR-20a	CLIP-seq
MIRT1369848	hsa-miR-20b	CLIP-seq
MIRT1369850	hsa-miR-221	CLIP-seq
MIRT1369851	hsa-miR-222	CLIP-seq
MIRT1369852	hsa-miR-2276	CLIP-seq
MIRT1369854	hsa-miR-29a	CLIP-seq
MIRT1369855	hsa-miR-29b	CLIP-seq
MIRT1369856	hsa-miR-29c	CLIP-seq
MIRT1369857	hsa-miR-302a	CLIP-seq
MIRT1369858	hsa-miR-302b	CLIP-seq
MIRT1369859	hsa-miR-302c	CLIP-seq
MIRT1369860	hsa-miR-302d	CLIP-seq
MIRT1369861	hsa-miR-302e	CLIP-seq
MIRT2627414	hsa-miR-3119	CLIP-seq
MIRT2627415	hsa-miR-3155	CLIP-seq
MIRT2627416	hsa-miR-3155b	CLIP-seq
MIRT2433316	hsa-miR-3156-3p	CLIP-seq
MIRT2333210	hsa-miR-329	CLIP-seq
MIRT1369870	hsa-miR-34b	CLIP-seq
MIRT2627419	hsa-miR-3591-5p	CLIP-seq
MIRT1369873	hsa-miR-3622a-5p	CLIP-seq
MIRT2333211	hsa-miR-362-3p	CLIP-seq
MIRT1369874	hsa-miR-3647-3p	CLIP-seq
MIRT1369876	hsa-miR-3653	CLIP-seq
MIRT1369877	hsa-miR-3658	CLIP-seq
MIRT1369878	hsa-miR-3671	CLIP-seq
MIRT1369883	hsa-miR-372	CLIP-seq
MIRT1369884	hsa-miR-373	CLIP-seq
MIRT2109792	hsa-miR-3941	CLIP-seq
MIRT2433317	hsa-miR-4255	CLIP-seq
MIRT2109793	hsa-miR-4263	CLIP-seq
MIRT2627421	hsa-miR-4267	CLIP-seq
MIRT1369890	hsa-miR-4275	CLIP-seq
MIRT1369893	hsa-miR-4291	CLIP-seq
MIRT2627422	hsa-miR-4301	CLIP-seq
MIRT2627423	hsa-miR-4302	CLIP-seq
MIRT2627424	hsa-miR-4306	CLIP-seq
MIRT1369894	hsa-miR-4310	CLIP-seq
MIRT2109795	hsa-miR-4420	CLIP-seq
MIRT1369896	hsa-miR-4423-3p	CLIP-seq
MIRT2627425	hsa-miR-4426	CLIP-seq
MIRT2333214	hsa-miR-4446-5p	CLIP-seq
MIRT2109796	hsa-miR-4462	CLIP-seq
MIRT2109797	hsa-miR-4475	CLIP-seq
MIRT2627426	hsa-miR-4484	CLIP-seq
MIRT2433318	hsa-miR-4517	CLIP-seq
MIRT2627427	hsa-miR-4534	CLIP-seq
MIRT2627428	hsa-miR-4644	CLIP-seq
MIRT2627429	hsa-miR-4647	CLIP-seq
MIRT2333215	hsa-miR-466	CLIP-seq
MIRT2627430	hsa-miR-4662b	CLIP-seq
MIRT2333217	hsa-miR-4672	CLIP-seq
MIRT2627431	hsa-miR-4678	CLIP-seq
MIRT1369905	hsa-miR-4696	CLIP-seq
MIRT2627433	hsa-miR-4729	CLIP-seq
MIRT2627437	hsa-miR-4795-3p	CLIP-seq
MIRT2627438	hsa-miR-4797-5p	CLIP-seq
MIRT1369915	hsa-miR-4799-5p	CLIP-seq
MIRT1369918	hsa-miR-513b	CLIP-seq
MIRT2627441	hsa-miR-514	CLIP-seq
MIRT2627442	hsa-miR-514b-3p	CLIP-seq
MIRT1369919	hsa-miR-519d	CLIP-seq
MIRT1369920	hsa-miR-520a-3p	CLIP-seq
MIRT1369921	hsa-miR-520b	CLIP-seq
MIRT1369922	hsa-miR-520c-3p	CLIP-seq
MIRT1369923	hsa-miR-520d-3p	CLIP-seq
MIRT1369924	hsa-miR-520e	CLIP-seq
MIRT2627443	hsa-miR-539	CLIP-seq
MIRT2627444	hsa-miR-548an	CLIP-seq
MIRT1369928	hsa-miR-548v	CLIP-seq
MIRT1369930	hsa-miR-561	CLIP-seq
MIRT2109805	hsa-miR-563	CLIP-seq
MIRT2627445	hsa-miR-576-5p	CLIP-seq
MIRT1369932	hsa-miR-583	CLIP-seq
MIRT2333224	hsa-miR-603	CLIP-seq
MIRT1369936	hsa-miR-607	CLIP-seq
MIRT1369937	hsa-miR-624	CLIP-seq
MIRT2333226	hsa-miR-634	CLIP-seq
MIRT1369943	hsa-miR-93	CLIP-seq
MIRT1369944	hsa-miR-944	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	18239682
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	25882817, 26094769
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	18287541, 26094769
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006915	Process	Apoptotic process	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030334	Process	Regulation of cell migration	IBA
GO:0030334	Process	Regulation of cell migration	IEA
GO:0030334	Process	Regulation of cell migration	IMP	26818812
GO:0030334	Process	Regulation of cell migration	ISS
GO:0031122	Process	Cytoplasmic microtubule organization	IMP	18287541
GO:0031252	Component	Cell leading edge	IEA
GO:0031252	Component	Cell leading edge	ISS
GO:0035556	Process	Intracellular signal transduction	IBA
GO:0042802	Function	Identical protein binding	IPI	18239682
GO:0042803	Function	Protein homodimerization activity	IDA	18239682, 22203681
GO:0042981	Process	Regulation of apoptotic process	IBA
GO:0042981	Process	Regulation of apoptotic process	IDA	22203681
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0046777	Process	Protein autophosphorylation	IDA	18239682
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	26094769
GO:0051893	Process	Regulation of focal adhesion assembly	IDA	23128389
GO:0070062	Component	Extracellular exosome	HDA	19056867, 19199708
GO:0106310	Function	Protein serine kinase activity	IEA

Other IDs

• MIM: 616563
• HGNC: 11088
• e!Ensembl: ENSG00000065613

Protein

• UniProt ID: Q9H2G2
• Protein name: STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)
• Protein function: Mediates apoptosis and actin stress fiber dissolution.
• PDB: 2J51, 2JFL, 2JFM, 2UV2, 4USF, 6HVD, 8BEM
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00069	Pkinase	34 → 292	Protein kinase domain	Domain
  PF12474	PKK	852 → 990	Polo kinase kinase	Family
  PF12474	PKK	1020 → 1160	Polo kinase kinase	Family

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle. {ECO:0000269|PubMed:10699464}.
• Sequence:

  MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLA
  AAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVM
  LELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKN
  TRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNP
  MRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTVDSNKPI
  RELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQNACIL
  ESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDRTAVIK
  ENEREKRPKLENLPDTEDQETVDINSVSEGKENNIMITLETNIEHNLKSEEEKDQEKQQM
  FENKLIKSEEIKDTILQTVDLVSQETGEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKD
  VISNTSDVIGTCEAADVAQKVDEDSAEDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEV
  PIKEIVEMNEIEEGKNKEQAINSSENIMDINEEPGTTEGEEITESSSTEEMEVRSVVADT
  DQKALGSEVQDASKVTTQIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSG
  ENKEEIGSLSKTETILPPESENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSI
  SLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKE
  EQRAQQQLNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRL
  RDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQE
  QEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKH
  QLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAK
  TRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDLQLQCEA
  NVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQ
  EVFFKMTGESECLNPSTQSRISKFYPIPSLHSTGS

• Sequence length: 1235

Pathways

KEGG:

Oocyte meiosis

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Acute myeloid leukemia	Likely benign	rs775328978	RCV005905306
Malignant tumor of esophagus	Likely benign	rs775328978	RCV005905307
Thymoma	Likely benign	rs775328978	RCV005905308

Associations from Text Mining
Disease Name	Relationship Type	References
Adenocarcinoma of Lung	Associate	35982906
Leiomyoma	Associate	35689443
Lung Neoplasms	Associate	28204826
Neoplasms	Inhibit	21944251, 23594797
Neoplasms	Associate	37240218, 39780110
Prostatic Neoplasms	Associate	32859632
Prostatitis	Associate	10660600