Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9733
Gene name Gene Name - the full gene name approved by the HGNC.	Spliceosome associated factor 3, U4/U6 recycling protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SART3
Synonyms (NCBI Gene) Gene synonyms aliases	DSAP1, P100, RP11-13G14, TIP110, p110, p110(nrb)
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12q23.3
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be use

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miRTarBase ID	miRNA	Experiments	Reference
MIRT051408	hsa-let-7f-5p	CLASH	23622248
MIRT049146	hsa-miR-92a-3p	CLASH	23622248
MIRT046568	hsa-let-7g-5p	CLASH	23622248
MIRT043962	hsa-miR-378a-5p	CLASH	23622248
MIRT552236	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT552235	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT552234	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT552233	hsa-miR-6856-3p	PAR-CLIP	21572407
MIRT552232	hsa-miR-4323	PAR-CLIP	21572407
MIRT552231	hsa-miR-3163	PAR-CLIP	21572407
MIRT552229	hsa-miR-5692b	PAR-CLIP	21572407
MIRT552230	hsa-miR-5692c	PAR-CLIP	21572407
MIRT552228	hsa-miR-3189-5p	PAR-CLIP	21572407
MIRT552236	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT552235	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT552234	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT552233	hsa-miR-6856-3p	PAR-CLIP	21572407
MIRT552232	hsa-miR-4323	PAR-CLIP	21572407
MIRT552231	hsa-miR-3163	PAR-CLIP	21572407
MIRT552229	hsa-miR-5692b	PAR-CLIP	21572407
MIRT552230	hsa-miR-5692c	PAR-CLIP	21572407
MIRT552228	hsa-miR-3189-5p	PAR-CLIP	21572407
MIRT1326377	hsa-miR-1203	CLIP-seq
MIRT1326378	hsa-miR-1260	CLIP-seq
MIRT1326379	hsa-miR-1260b	CLIP-seq
MIRT1326380	hsa-miR-1284	CLIP-seq
MIRT1326381	hsa-miR-1305	CLIP-seq
MIRT1326382	hsa-miR-132	CLIP-seq
MIRT1326383	hsa-miR-188-3p	CLIP-seq
MIRT1326384	hsa-miR-193a-3p	CLIP-seq
MIRT1326385	hsa-miR-193b	CLIP-seq
MIRT1326386	hsa-miR-212	CLIP-seq
MIRT1326387	hsa-miR-214	CLIP-seq
MIRT1326388	hsa-miR-219-1-3p	CLIP-seq
MIRT1326389	hsa-miR-300	CLIP-seq
MIRT1326390	hsa-miR-3150b-3p	CLIP-seq
MIRT1326391	hsa-miR-3156-3p	CLIP-seq
MIRT1326392	hsa-miR-330-3p	CLIP-seq
MIRT1326393	hsa-miR-337-3p	CLIP-seq
MIRT1326394	hsa-miR-3545-3p	CLIP-seq
MIRT1326395	hsa-miR-3619-5p	CLIP-seq
MIRT1326396	hsa-miR-3646	CLIP-seq
MIRT1326397	hsa-miR-3665	CLIP-seq
MIRT1326398	hsa-miR-381	CLIP-seq
MIRT1326399	hsa-miR-3926	CLIP-seq
MIRT1326400	hsa-miR-3938	CLIP-seq
MIRT1326401	hsa-miR-4422	CLIP-seq
MIRT1326402	hsa-miR-4435	CLIP-seq
MIRT1326403	hsa-miR-4487	CLIP-seq
MIRT1326404	hsa-miR-4520a-3p	CLIP-seq
MIRT1326405	hsa-miR-4520b-3p	CLIP-seq
MIRT1326406	hsa-miR-4529-3p	CLIP-seq
MIRT1326407	hsa-miR-4539	CLIP-seq
MIRT1326408	hsa-miR-455-3p	CLIP-seq
MIRT1326409	hsa-miR-4666-3p	CLIP-seq
MIRT1326410	hsa-miR-4677-3p	CLIP-seq
MIRT1326411	hsa-miR-4679	CLIP-seq
MIRT1326412	hsa-miR-4689	CLIP-seq
MIRT1326413	hsa-miR-4711-3p	CLIP-seq
MIRT1326414	hsa-miR-4719	CLIP-seq
MIRT1326415	hsa-miR-4724-5p	CLIP-seq
MIRT1326416	hsa-miR-4743	CLIP-seq
MIRT1326417	hsa-miR-4778-5p	CLIP-seq
MIRT1326418	hsa-miR-4784	CLIP-seq
MIRT1326419	hsa-miR-494	CLIP-seq
MIRT1326420	hsa-miR-548ae	CLIP-seq
MIRT1326421	hsa-miR-548aj	CLIP-seq
MIRT1326422	hsa-miR-548am	CLIP-seq
MIRT1326423	hsa-miR-548s	CLIP-seq
MIRT1326424	hsa-miR-548x	CLIP-seq
MIRT1326425	hsa-miR-549	CLIP-seq
MIRT1326426	hsa-miR-570	CLIP-seq
MIRT1326427	hsa-miR-577	CLIP-seq
MIRT1326428	hsa-miR-607	CLIP-seq
MIRT1326429	hsa-miR-617	CLIP-seq
MIRT1326430	hsa-miR-624	CLIP-seq
MIRT1326431	hsa-miR-642a	CLIP-seq
MIRT1326432	hsa-miR-662	CLIP-seq
MIRT1326433	hsa-miR-761	CLIP-seq
MIRT1326434	hsa-miR-892a	CLIP-seq
MIRT2096884	hsa-miR-1207-3p	CLIP-seq
MIRT1326382	hsa-miR-132	CLIP-seq
MIRT2096885	hsa-miR-1825	CLIP-seq
MIRT2096886	hsa-miR-1911	CLIP-seq
MIRT1326384	hsa-miR-193a-3p	CLIP-seq
MIRT1326385	hsa-miR-193b	CLIP-seq
MIRT2096887	hsa-miR-2052	CLIP-seq
MIRT1326386	hsa-miR-212	CLIP-seq
MIRT1326387	hsa-miR-214	CLIP-seq
MIRT2096888	hsa-miR-223	CLIP-seq
MIRT2096889	hsa-miR-297	CLIP-seq
MIRT2096890	hsa-miR-3126-5p	CLIP-seq
MIRT2096891	hsa-miR-3140-3p	CLIP-seq
MIRT2096892	hsa-miR-3150a-3p	CLIP-seq
MIRT2096893	hsa-miR-3175	CLIP-seq
MIRT2096894	hsa-miR-320a	CLIP-seq
MIRT2096895	hsa-miR-320b	CLIP-seq
MIRT2096896	hsa-miR-320c	CLIP-seq
MIRT2096897	hsa-miR-320d	CLIP-seq
MIRT2096898	hsa-miR-33a	CLIP-seq
MIRT2096899	hsa-miR-33b	CLIP-seq
MIRT1326394	hsa-miR-3545-3p	CLIP-seq
MIRT2096900	hsa-miR-3545-5p	CLIP-seq
MIRT2096901	hsa-miR-3609	CLIP-seq
MIRT2096902	hsa-miR-3613-3p	CLIP-seq
MIRT2096903	hsa-miR-3616-5p	CLIP-seq
MIRT1326395	hsa-miR-3619-5p	CLIP-seq
MIRT2096904	hsa-miR-3647-5p	CLIP-seq
MIRT1326397	hsa-miR-3665	CLIP-seq
MIRT2096905	hsa-miR-3925-5p	CLIP-seq
MIRT1326399	hsa-miR-3926	CLIP-seq
MIRT2096906	hsa-miR-3973	CLIP-seq
MIRT2096907	hsa-miR-4252	CLIP-seq
MIRT2096908	hsa-miR-4290	CLIP-seq
MIRT2096909	hsa-miR-4291	CLIP-seq
MIRT2096910	hsa-miR-4302	CLIP-seq
MIRT2096911	hsa-miR-4328	CLIP-seq
MIRT2096912	hsa-miR-4419a	CLIP-seq
MIRT2096913	hsa-miR-4429	CLIP-seq
MIRT2096914	hsa-miR-4501	CLIP-seq
MIRT2096915	hsa-miR-4510	CLIP-seq
MIRT2096916	hsa-miR-4517	CLIP-seq
MIRT2096917	hsa-miR-451b	CLIP-seq
MIRT1326408	hsa-miR-455-3p	CLIP-seq
MIRT2096918	hsa-miR-4670-3p	CLIP-seq
MIRT2096919	hsa-miR-4682	CLIP-seq
MIRT2096920	hsa-miR-4694-3p	CLIP-seq
MIRT1326414	hsa-miR-4719	CLIP-seq
MIRT2096921	hsa-miR-4727-5p	CLIP-seq
MIRT2096922	hsa-miR-4738-3p	CLIP-seq
MIRT2096923	hsa-miR-4742-3p	CLIP-seq
MIRT2096924	hsa-miR-4769-3p	CLIP-seq
MIRT1326417	hsa-miR-4778-5p	CLIP-seq
MIRT2096925	hsa-miR-4793-5p	CLIP-seq
MIRT2096926	hsa-miR-520g	CLIP-seq
MIRT2096927	hsa-miR-520h	CLIP-seq
MIRT2096928	hsa-miR-522	CLIP-seq
MIRT2096929	hsa-miR-544	CLIP-seq
MIRT2096930	hsa-miR-545	CLIP-seq
MIRT2096931	hsa-miR-548ah	CLIP-seq
MIRT1326423	hsa-miR-548s	CLIP-seq
MIRT2096932	hsa-miR-567	CLIP-seq
MIRT1326426	hsa-miR-570	CLIP-seq
MIRT2096933	hsa-miR-573	CLIP-seq
MIRT1326433	hsa-miR-761	CLIP-seq
MIRT2096934	hsa-miR-939	CLIP-seq
MIRT2321228	hsa-miR-1257	CLIP-seq
MIRT2321229	hsa-miR-3120-5p	CLIP-seq
MIRT2096890	hsa-miR-3126-5p	CLIP-seq
MIRT2321230	hsa-miR-3618	CLIP-seq
MIRT2096908	hsa-miR-4290	CLIP-seq
MIRT2096912	hsa-miR-4419a	CLIP-seq
MIRT2096915	hsa-miR-4510	CLIP-seq
MIRT2096916	hsa-miR-4517	CLIP-seq
MIRT2321231	hsa-miR-452	CLIP-seq
MIRT2321232	hsa-miR-4661-5p	CLIP-seq
MIRT2321233	hsa-miR-4676-3p	CLIP-seq
MIRT1326410	hsa-miR-4677-3p	CLIP-seq
MIRT1326411	hsa-miR-4679	CLIP-seq
MIRT2321234	hsa-miR-4693-5p	CLIP-seq
MIRT2096922	hsa-miR-4738-3p	CLIP-seq
MIRT1326417	hsa-miR-4778-5p	CLIP-seq
MIRT2321235	hsa-miR-550a	CLIP-seq
MIRT2321236	hsa-miR-934	CLIP-seq
MIRT2096890	hsa-miR-3126-5p	CLIP-seq
MIRT2096908	hsa-miR-4290	CLIP-seq
MIRT2096912	hsa-miR-4419a	CLIP-seq
MIRT2096915	hsa-miR-4510	CLIP-seq
MIRT2096916	hsa-miR-4517	CLIP-seq
MIRT2321228	hsa-miR-1257	CLIP-seq
MIRT2617383	hsa-miR-1273g	CLIP-seq
MIRT1326380	hsa-miR-1284	CLIP-seq
MIRT1326382	hsa-miR-132	CLIP-seq
MIRT2617384	hsa-miR-1323	CLIP-seq
MIRT2617385	hsa-miR-151-5p	CLIP-seq
MIRT2617386	hsa-miR-151b	CLIP-seq
MIRT2617387	hsa-miR-1909	CLIP-seq
MIRT2096886	hsa-miR-1911	CLIP-seq
MIRT2096887	hsa-miR-2052	CLIP-seq
MIRT1326386	hsa-miR-212	CLIP-seq
MIRT1326387	hsa-miR-214	CLIP-seq
MIRT2096888	hsa-miR-223	CLIP-seq
MIRT1326389	hsa-miR-300	CLIP-seq
MIRT2321229	hsa-miR-3120-5p	CLIP-seq
MIRT2096890	hsa-miR-3126-5p	CLIP-seq
MIRT2617388	hsa-miR-3127-3p	CLIP-seq
MIRT2096891	hsa-miR-3140-3p	CLIP-seq
MIRT2617389	hsa-miR-3190	CLIP-seq
MIRT2617390	hsa-miR-3200-5p	CLIP-seq
MIRT1326393	hsa-miR-337-3p	CLIP-seq
MIRT2617391	hsa-miR-338-3p	CLIP-seq
MIRT1326395	hsa-miR-3619-5p	CLIP-seq
MIRT1326397	hsa-miR-3665	CLIP-seq
MIRT1326398	hsa-miR-381	CLIP-seq
MIRT2096905	hsa-miR-3925-5p	CLIP-seq
MIRT2617392	hsa-miR-3944-5p	CLIP-seq
MIRT2617393	hsa-miR-409-3p	CLIP-seq
MIRT2096907	hsa-miR-4252	CLIP-seq
MIRT2096908	hsa-miR-4290	CLIP-seq
MIRT2096909	hsa-miR-4291	CLIP-seq
MIRT2617394	hsa-miR-4307	CLIP-seq
MIRT2096911	hsa-miR-4328	CLIP-seq
MIRT2096912	hsa-miR-4419a	CLIP-seq
MIRT2617395	hsa-miR-4509	CLIP-seq
MIRT2096915	hsa-miR-4510	CLIP-seq
MIRT2096916	hsa-miR-4517	CLIP-seq
MIRT2096917	hsa-miR-451b	CLIP-seq
MIRT2617396	hsa-miR-4530	CLIP-seq
MIRT1326408	hsa-miR-455-3p	CLIP-seq
MIRT2617397	hsa-miR-4650-5p	CLIP-seq
MIRT2617398	hsa-miR-4652-3p	CLIP-seq
MIRT1326409	hsa-miR-4666-3p	CLIP-seq
MIRT1326410	hsa-miR-4677-3p	CLIP-seq
MIRT1326411	hsa-miR-4679	CLIP-seq
MIRT2096919	hsa-miR-4682	CLIP-seq
MIRT2617399	hsa-miR-4684-3p	CLIP-seq
MIRT2617400	hsa-miR-4709-3p	CLIP-seq
MIRT1326414	hsa-miR-4719	CLIP-seq
MIRT2617401	hsa-miR-4729	CLIP-seq
MIRT2617402	hsa-miR-4733-3p	CLIP-seq
MIRT2617403	hsa-miR-4737	CLIP-seq
MIRT2096922	hsa-miR-4738-3p	CLIP-seq
MIRT2617404	hsa-miR-4744	CLIP-seq
MIRT2617405	hsa-miR-4766-5p	CLIP-seq
MIRT1326417	hsa-miR-4778-5p	CLIP-seq
MIRT2617406	hsa-miR-488	CLIP-seq
MIRT2617407	hsa-miR-508-5p	CLIP-seq
MIRT2617408	hsa-miR-518a-5p	CLIP-seq
MIRT2617409	hsa-miR-520d-5p	CLIP-seq
MIRT2617410	hsa-miR-524-5p	CLIP-seq
MIRT2617411	hsa-miR-527	CLIP-seq
MIRT2096930	hsa-miR-545	CLIP-seq
MIRT2617412	hsa-miR-548o	CLIP-seq
MIRT1326426	hsa-miR-570	CLIP-seq
MIRT2617413	hsa-miR-616	CLIP-seq
MIRT1326429	hsa-miR-617	CLIP-seq
MIRT1326431	hsa-miR-642a	CLIP-seq
MIRT2617414	hsa-miR-7	CLIP-seq
MIRT1326433	hsa-miR-761	CLIP-seq
MIRT2617415	hsa-miR-766	CLIP-seq
MIRT2617383	hsa-miR-1273g	CLIP-seq
MIRT1326380	hsa-miR-1284	CLIP-seq
MIRT1326382	hsa-miR-132	CLIP-seq
MIRT2617384	hsa-miR-1323	CLIP-seq
MIRT2617385	hsa-miR-151-5p	CLIP-seq
MIRT2617386	hsa-miR-151b	CLIP-seq
MIRT2617387	hsa-miR-1909	CLIP-seq
MIRT2096886	hsa-miR-1911	CLIP-seq
MIRT2096887	hsa-miR-2052	CLIP-seq
MIRT1326386	hsa-miR-212	CLIP-seq
MIRT1326387	hsa-miR-214	CLIP-seq
MIRT1326389	hsa-miR-300	CLIP-seq
MIRT2321229	hsa-miR-3120-5p	CLIP-seq
MIRT2096890	hsa-miR-3126-5p	CLIP-seq
MIRT2617388	hsa-miR-3127-3p	CLIP-seq
MIRT2617389	hsa-miR-3190	CLIP-seq
MIRT2617390	hsa-miR-3200-5p	CLIP-seq
MIRT1326393	hsa-miR-337-3p	CLIP-seq
MIRT2617391	hsa-miR-338-3p	CLIP-seq
MIRT1326395	hsa-miR-3619-5p	CLIP-seq
MIRT1326397	hsa-miR-3665	CLIP-seq
MIRT1326398	hsa-miR-381	CLIP-seq
MIRT2617392	hsa-miR-3944-5p	CLIP-seq
MIRT2096907	hsa-miR-4252	CLIP-seq
MIRT2096908	hsa-miR-4290	CLIP-seq
MIRT2096909	hsa-miR-4291	CLIP-seq
MIRT2617394	hsa-miR-4307	CLIP-seq
MIRT2096912	hsa-miR-4419a	CLIP-seq
MIRT2617395	hsa-miR-4509	CLIP-seq
MIRT2096915	hsa-miR-4510	CLIP-seq
MIRT2096916	hsa-miR-4517	CLIP-seq
MIRT2096917	hsa-miR-451b	CLIP-seq
MIRT2617396	hsa-miR-4530	CLIP-seq
MIRT1326408	hsa-miR-455-3p	CLIP-seq
MIRT2617397	hsa-miR-4650-5p	CLIP-seq
MIRT2617398	hsa-miR-4652-3p	CLIP-seq
MIRT1326409	hsa-miR-4666-3p	CLIP-seq
MIRT1326410	hsa-miR-4677-3p	CLIP-seq
MIRT1326411	hsa-miR-4679	CLIP-seq
MIRT2096919	hsa-miR-4682	CLIP-seq
MIRT1326414	hsa-miR-4719	CLIP-seq
MIRT2617401	hsa-miR-4729	CLIP-seq
MIRT2617402	hsa-miR-4733-3p	CLIP-seq
MIRT2617403	hsa-miR-4737	CLIP-seq
MIRT2096922	hsa-miR-4738-3p	CLIP-seq
MIRT2617404	hsa-miR-4744	CLIP-seq
MIRT2617405	hsa-miR-4766-5p	CLIP-seq
MIRT1326417	hsa-miR-4778-5p	CLIP-seq
MIRT2617406	hsa-miR-488	CLIP-seq
MIRT2617407	hsa-miR-508-5p	CLIP-seq
MIRT2617409	hsa-miR-520d-5p	CLIP-seq
MIRT2617410	hsa-miR-524-5p	CLIP-seq
MIRT2096930	hsa-miR-545	CLIP-seq
MIRT2617412	hsa-miR-548o	CLIP-seq
MIRT1326426	hsa-miR-570	CLIP-seq
MIRT2617413	hsa-miR-616	CLIP-seq
MIRT1326429	hsa-miR-617	CLIP-seq
MIRT1326431	hsa-miR-642a	CLIP-seq
MIRT2617414	hsa-miR-7	CLIP-seq
MIRT1326433	hsa-miR-761	CLIP-seq
MIRT2617415	hsa-miR-766	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
MYC	Unknown	21447833

Show/Hide all(44)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000244	Process	Spliceosomal tri-snRNP complex assembly	IDA	12032085, 20595234
GO:0000387	Process	Spliceosomal snRNP assembly	IDA	15314151
GO:0000387	Process	Spliceosomal snRNP assembly	IDA	14749385, 15314151
GO:0000398	Process	MRNA splicing, via spliceosome	IBA
GO:0000398	Process	MRNA splicing, via spliceosome	IDA	15314151
GO:0000902	Process	Cell morphogenesis	IEA
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	11477570, 15314151, 16713569, 17932509, 20595234, 25544563, 32296183, 33961781
GO:0005634	Component	Nucleus	IDA	32839293
GO:0005634	Component	Nucleus	IDA	24526689
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IBA
GO:0005654	Component	Nucleoplasm	IDA	12578909
GO:0005654	Component	Nucleoplasm	IEA
GO:0005691	Component	U6atac snRNP	IDA	14749385
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0006334	Process	Nucleosome assembly	IDA	24526689
GO:0006396	Process	RNA processing	IEA
GO:0006397	Process	MRNA processing	IEA
GO:0008380	Process	RNA splicing	IEA
GO:0010468	Process	Regulation of gene expression	IDA	21447833
GO:0015030	Component	Cajal body	IDA	12578909
GO:0015030	Component	Cajal body	IEA
GO:0016607	Component	Nuclear speck	IEA
GO:0017070	Function	U6 snRNA binding	IDA	15314151
GO:0017070	Function	U6 snRNA binding	IDA	12032085, 14749385, 15314151
GO:0030621	Function	U4 snRNA binding	IDA	15314151
GO:0030621	Function	U4 snRNA binding	IDA	12032085, 14749385
GO:0030624	Function	U6atac snRNA binding	IDA	14749385
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	32839293
GO:0042393	Function	Histone binding	IDA	24526689
GO:0046540	Component	U4/U6 x U5 tri-snRNP complex	IDA	12032085
GO:0048872	Process	Homeostasis of number of cells	IEA
GO:0051252	Process	Regulation of RNA metabolic process	IDA	32839293
GO:0051252	Process	Regulation of RNA metabolic process	IDA	32839293
GO:0061574	Component	ASAP complex	IBA
GO:0071001	Component	U4/U6 snRNP	IDA	12032085
GO:0071002	Component	U4atac/U6atac snRNP	IDA	14749385
GO:0071425	Process	Hematopoietic stem cell proliferation	IEA
GO:0140673	Process	Transcription elongation-coupled chromatin remodeling	IDA	24526689
GO:1990381	Function	Ubiquitin-specific protease binding	IPI	20595234, 24526689

MIM	HGNC	e!Ensembl
611684	16860	ENSG00000075856

Protein

UniProt ID

Q15020

Protein name

Spliceosome associated factor 3, U4/U6 recycling protein (Squamous cell carcinoma antigen recognized by T-cells 3) (SART-3) (Tat-interacting protein of 110 kDa) (Tip110) (p110 nuclear RNA-binding protein)

Protein function

U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation (PubMed:12032085). Also binds U6atac

PDB

2DO4 , 5CTQ , 5CTR , 5CTT , 5JJW , 5JJX , 5JPZ , 7XX8 , 7XX9

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00076	RRM_1	706 → 775	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain
PF00076	RRM_1	803 → 872	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain
PF16605	LSM_int_assoc	877 → 938		Disordered
PF05391	Lsm_interact	944 → 962	Lsm interaction motif	Motif

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:11959860}.

Sequence

MATAAETSASEPEAESKAGPKADGEEDEVKAARTRRKVLSRAVAAATYKTMGPAWDQQEE
GVSESDGDEYAMASSAESSPGEYEWEYDEEEEKNQLEIERLEEQLSINVYDYNCHVDLIR
LLRLEGELTKVRMARQKMSEIFPLTEELWLEWLHDEISMAQDGLDREHVYDLFEKAVKDY
ICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLALWEAYREFESAIVE
AARLEKVHSLFRRQLAIPLYDMEATFAEYEEWSEDPIPESVIQNYNKALQQLEKYKPYEE
ALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKV
KDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEI
WQAYLDYLRRRVDFKQDSSKELEELRAAFTRALEYLKQEVEERFNESGDPSCVIMQNWAR
IEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSD
YPEHVCEVLLTMERTEGSLEDWDIAVQKTETRLARVNEQRMKAAEKEAALVQQEEEKAEQ
RKRARAEKKALKKKKKIRGPEKRGADEDDEKEWGDDEEEQPSKRRRVENSIPAAGETQNV
EVAAGPAGKCAAVDVEPPSKQKEKAASLKRDMPKVLHDSSKDSITVFVSNLPYSMQEPDT
KLRPLFEACGEVVQIRPIFSNRGDFRGYCYVEFKEEKSALQALEMDRKSVEGRPMFVSPC
VDKSKNPDFKVFRYSTSLEKHKLFISGLPFSCTKEELEEICKAHGTVKDLRLVTNRAGKP
KGLAYVEYENESQASQAVMKMDGMTIKENIIKVAISNPPQRKVPEKPETRKAPGGPMLLP
QTYGARGKGRTQLSLLPRALQRPSAAAPQAENGPAAAPAVAAPAATEAPKMSNADFAKLF
LRK

Sequence length

963

Interactions

View interactions

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disseminated Superficial Actinic Porokeratosis	disseminated superficial actinic porokeratosis	N/A	N/A	GenCC
Neurodevelopmental Disorders	complex neurodevelopmental disorder	N/A	N/A	GenCC
Porokeratosis	Porokeratosis 3, disseminated superficial actinic type	N/A	N/A	ClinVar

Show/Hide Text Mining Associations (25)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Breast Neoplasms	Associate	11286471, 25990212
Carcinoma Hepatocellular	Associate	37632835
Carcinoma Non Small Cell Lung	Associate	31619517
Choline Deficiency	Inhibit	15147518
Colonic Neoplasms	Associate	11920522
Colorectal Neoplasms	Associate	11920522
Drug Hypersensitivity	Inhibit	29590477
Esophageal Neoplasms	Associate	11402621
Glioma	Inhibit	26047657
Histiocytic Sarcoma	Associate	11398844
Hypoxia Brain	Inhibit	30119675
Liver Neoplasms	Associate	36789492
Lung Neoplasms	Associate	31619517
Melanoma	Associate	30119675
Mitochondrial Diseases	Inhibit	23239023
Mouth Neoplasms	Associate	11402621
Musculoskeletal Diseases	Associate	11398844
Neoplasm Metastasis	Associate	30119675
Neoplasms	Associate	10760694, 11092984, 11286471, 11398844, 11920522, 23822148, 29590477
Non alcoholic Fatty Liver Disease	Associate	37993474
Osteosarcoma	Associate	11398844
Ovarian Neoplasms	Associate	32385243
Seminoma	Associate	11073819
Sleep Deprivation	Inhibit	23239023
Stomach Neoplasms	Associate	10760694

SART3 (spliceosome associated factor 3, U4/U6 recycling protein)