Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9726
Gene name Gene Name - the full gene name approved by the HGNC.	Zinc finger protein 646
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ZNF646
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	16p11.2

Show/Hide all(103)

miRTarBase ID	miRNA	Experiments	Reference
MIRT046158	hsa-miR-30b-5p	CLASH	23622248
MIRT044630	hsa-miR-320a	CLASH	23622248
MIRT044002	hsa-miR-378a-5p	CLASH	23622248
MIRT442704	hsa-miR-22-3p	PAR-CLIP	22291592
MIRT442703	hsa-miR-4803	PAR-CLIP	22291592
MIRT442702	hsa-miR-3190-5p	PAR-CLIP	22291592
MIRT442701	hsa-miR-1254	PAR-CLIP	22291592
MIRT442700	hsa-miR-3116	PAR-CLIP	22291592
MIRT442699	hsa-miR-661	PAR-CLIP	22291592
MIRT442698	hsa-miR-6882-3p	PAR-CLIP	22291592
MIRT442697	hsa-miR-6828-5p	PAR-CLIP	22291592
MIRT442696	hsa-miR-671-5p	PAR-CLIP	22291592
MIRT442695	hsa-miR-3926	PAR-CLIP	22291592
MIRT442693	hsa-miR-6079	PAR-CLIP	22291592
MIRT442694	hsa-miR-548s	PAR-CLIP	22291592
MIRT442704	hsa-miR-22-3p	PAR-CLIP	22100165
MIRT442703	hsa-miR-4803	PAR-CLIP	22100165
MIRT442702	hsa-miR-3190-5p	PAR-CLIP	22100165
MIRT442701	hsa-miR-1254	PAR-CLIP	22100165
MIRT442700	hsa-miR-3116	PAR-CLIP	22100165
MIRT442699	hsa-miR-661	PAR-CLIP	22100165
MIRT442698	hsa-miR-6882-3p	PAR-CLIP	22100165
MIRT442697	hsa-miR-6828-5p	PAR-CLIP	22100165
MIRT442696	hsa-miR-671-5p	PAR-CLIP	22100165
MIRT442695	hsa-miR-3926	PAR-CLIP	22100165
MIRT442693	hsa-miR-6079	PAR-CLIP	22100165
MIRT442694	hsa-miR-548s	PAR-CLIP	22100165
MIRT442704	hsa-miR-22-3p	PAR-CLIP	22100165
MIRT442703	hsa-miR-4803	PAR-CLIP	22100165
MIRT442702	hsa-miR-3190-5p	PAR-CLIP	22100165
MIRT442701	hsa-miR-1254	PAR-CLIP	22100165
MIRT442700	hsa-miR-3116	PAR-CLIP	22100165
MIRT442699	hsa-miR-661	PAR-CLIP	22100165
MIRT442698	hsa-miR-6882-3p	PAR-CLIP	22100165
MIRT442697	hsa-miR-6828-5p	PAR-CLIP	22100165
MIRT442696	hsa-miR-671-5p	PAR-CLIP	22100165
MIRT442695	hsa-miR-3926	PAR-CLIP	22100165
MIRT442693	hsa-miR-6079	PAR-CLIP	22100165
MIRT442694	hsa-miR-548s	PAR-CLIP	22100165
MIRT442704	hsa-miR-22-3p	PAR-CLIP	22291592
MIRT442703	hsa-miR-4803	PAR-CLIP	22291592
MIRT442702	hsa-miR-3190-5p	PAR-CLIP	22291592
MIRT442701	hsa-miR-1254	PAR-CLIP	22291592
MIRT442700	hsa-miR-3116	PAR-CLIP	22291592
MIRT442699	hsa-miR-661	PAR-CLIP	22291592
MIRT442698	hsa-miR-6882-3p	PAR-CLIP	22291592
MIRT442697	hsa-miR-6828-5p	PAR-CLIP	22291592
MIRT442696	hsa-miR-671-5p	PAR-CLIP	22291592
MIRT442695	hsa-miR-3926	PAR-CLIP	22291592
MIRT442693	hsa-miR-6079	PAR-CLIP	22291592
MIRT442694	hsa-miR-548s	PAR-CLIP	22291592
MIRT442704	hsa-miR-22-3p	PAR-CLIP	22100165
MIRT442703	hsa-miR-4803	PAR-CLIP	22100165
MIRT442702	hsa-miR-3190-5p	PAR-CLIP	22100165
MIRT442701	hsa-miR-1254	PAR-CLIP	22100165
MIRT442700	hsa-miR-3116	PAR-CLIP	22100165
MIRT442699	hsa-miR-661	PAR-CLIP	22100165
MIRT442698	hsa-miR-6882-3p	PAR-CLIP	22100165
MIRT442697	hsa-miR-6828-5p	PAR-CLIP	22100165
MIRT442696	hsa-miR-671-5p	PAR-CLIP	22100165
MIRT442695	hsa-miR-3926	PAR-CLIP	22100165
MIRT442693	hsa-miR-6079	PAR-CLIP	22100165
MIRT442694	hsa-miR-548s	PAR-CLIP	22100165
MIRT442704	hsa-miR-22-3p	PAR-CLIP	22100165
MIRT442703	hsa-miR-4803	PAR-CLIP	22100165
MIRT442702	hsa-miR-3190-5p	PAR-CLIP	22100165
MIRT442701	hsa-miR-1254	PAR-CLIP	22100165
MIRT442700	hsa-miR-3116	PAR-CLIP	22100165
MIRT442699	hsa-miR-661	PAR-CLIP	22100165
MIRT442698	hsa-miR-6882-3p	PAR-CLIP	22100165
MIRT442697	hsa-miR-6828-5p	PAR-CLIP	22100165
MIRT442696	hsa-miR-671-5p	PAR-CLIP	22100165
MIRT442695	hsa-miR-3926	PAR-CLIP	22100165
MIRT442693	hsa-miR-6079	PAR-CLIP	22100165
MIRT442694	hsa-miR-548s	PAR-CLIP	22100165
MIRT1533392	hsa-miR-3121-3p	CLIP-seq
MIRT1533393	hsa-miR-3692	CLIP-seq
MIRT1533394	hsa-miR-4287	CLIP-seq
MIRT1533395	hsa-miR-4685-3p	CLIP-seq
MIRT1533396	hsa-miR-4742-5p	CLIP-seq
MIRT1533397	hsa-miR-520d-5p	CLIP-seq
MIRT1533398	hsa-miR-524-5p	CLIP-seq
MIRT1533399	hsa-miR-548p	CLIP-seq
MIRT1533400	hsa-miR-891b	CLIP-seq
MIRT2161373	hsa-miR-1253	CLIP-seq
MIRT2161374	hsa-miR-3150b-3p	CLIP-seq
MIRT2161375	hsa-miR-3175	CLIP-seq
MIRT2161376	hsa-miR-4434	CLIP-seq
MIRT2161377	hsa-miR-4457	CLIP-seq
MIRT2161378	hsa-miR-4516	CLIP-seq
MIRT2161379	hsa-miR-4784	CLIP-seq
MIRT2161380	hsa-miR-513b	CLIP-seq
MIRT2397654	hsa-miR-3153	CLIP-seq
MIRT2397655	hsa-miR-3189-3p	CLIP-seq
MIRT2397656	hsa-miR-4668-5p	CLIP-seq
MIRT2464475	hsa-miR-324-5p	CLIP-seq
MIRT1533394	hsa-miR-4287	CLIP-seq
MIRT2464476	hsa-miR-4292	CLIP-seq
MIRT2464477	hsa-miR-4308	CLIP-seq
MIRT2464478	hsa-miR-4469	CLIP-seq
MIRT2464479	hsa-miR-4684-3p	CLIP-seq
MIRT1533395	hsa-miR-4685-3p	CLIP-seq
MIRT2464480	hsa-miR-4694-5p	CLIP-seq

Show/Hide all(7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	21873635
GO:0005515	Function	Protein binding	IPI	16189514, 19060904, 25416956, 31515488, 32296183
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of transcription, DNA-templated	IBA	21873635
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
619299	29004	ENSG00000167395

Protein

UniProt ID

O15015

Protein name

Zinc finger protein 646

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00096	zf-C2H2	48 → 70	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	75 → 97	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	239 → 261	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	374 → 396	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	617 → 639	Zinc finger, C2H2 type	Domain
PF13912	zf-C2H2_6	847 → 873		Domain
PF00096	zf-C2H2	1203 → 1225	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	1258 → 1280	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	1299 → 1321	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	1326 → 1348	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	1364 → 1386	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	1585 → 1607	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	1677 → 1699	Zinc finger, C2H2 type	Domain
PF13912	zf-C2H2_6	1731 → 1755		Domain

Sequence

MEDTPPSLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHP
GSLVNHRRTHETGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGE
TVSTDSWGQRLGSSEGWENQTKHTEETPDCESVPDPRAASGTWEDLPTRQREGLASHPGP
EDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYK
CSQCGKTYKHAGSLTNHRQSHTLGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCP
RVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTS
GELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGVYPCSLCSKQLFNAAALKNHV
RAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSL
VNHRHSHRTGEYQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPD
PVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAG
EKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFSCGACAKHFHTMAAMK
NHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAE
GNLESDGDCLQAESEGDKCGLERDETHFQGDKESGGTGEGLERKDASLLDNLDIPGEEGG
GTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHR
PCHPPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHR
RQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHIC
GCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGG
DAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGDFL
CPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMA
EEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSE
RPFSCEVCGRSYKHAGSLINHRQSHQTGHFGCQACSKGFSNLMSLKNHRRIHADPRRFRC
SECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRS
HETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLE
RHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERS
QSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHA
GDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTDRHYCL
LCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEE
ARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCT
QCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKA
FRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEEWTVAGSGAPVAPVT
GRGDLPLPPPPTPTTPLLDPSPQWPADLSFSL

Sequence length

1832

Interactions

View interactions

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158 View all (309 more)
Parkinson disease	Parkinson Disease	rs33939927, rs35801418, rs34805604, rs35870237, rs34995376, rs74315355, rs28940284, rs74315356, rs74315357, rs28940285, rs730880302, rs750664040, rs74315359, rs74315360, rs45539432 View all (84 more)	22451204

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Neuroticism	Neuroticism			GWAS

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining
Parkinson Disease	Associate	33436766

ZNF646 (zinc finger protein 646)