ULK2 (unc-51 like autophagy activating kinase 2)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9706 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Unc-51 like autophagy activating kinase 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ULK2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ATG1B, Unc51.2 |
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Chromosome
Chromosome number
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17 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17p11.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a cen |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q8IYT8 | |||||||||||||||
| Protein name | Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) | |||||||||||||||
| Protein function | Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback lo | |||||||||||||||
| PDB | 6QAT , 6QAU , 6QAV , 6YID | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1036 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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