ULK2 (unc-51 like autophagy activating kinase 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 9706 |
| Gene name | Unc-51 like autophagy activating kinase 2 |
| Gene symbol | ULK2 |
| Synonyms (NCBI Gene) |
ATG1BUnc51.2
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| Chromosome | 17 |
| Chromosome location | 17p11.2 |
| Summary | This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a cen |
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SNPs
SNP information provided by dbSNP.
1
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miRNA
miRNA information provided by mirtarbase database.
638
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
44
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8IYT8 | |||||||||||||||
| Protein name | Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) | |||||||||||||||
| Protein function | Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback lo | |||||||||||||||
| PDB | 6QAT , 6QAU , 6QAV , 6YID | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1036 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
2
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