Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9697
Gene name Gene Name - the full gene name approved by the HGNC.
Translocation associated membrane protein 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TRAM2
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6p12.2
Summary Summary of gene provided in NCBI Entrez Gene.
TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum (ER) membrane.[supplied by OMIM, Jul 2004]
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT023369 hsa-miR-122-5p Microarray 17612493
MIRT025874 hsa-miR-7-5p Sequencing 20371350
MIRT027751 hsa-miR-98-5p Microarray 19088304
MIRT029785 hsa-miR-26b-5p Microarray 19088304
MIRT520514 hsa-miR-32-5p PAR-CLIP 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 14749390
GO:0006616 Process SRP-dependent cotranslational protein targeting to membrane, translocation IEA
GO:0030176 Component Integral component of endoplasmic reticulum membrane IBA 21873635
GO:0032964 Process Collagen biosynthetic process IMP 14749390
GO:0045048 Process Protein insertion into ER membrane IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
608485 16855 ENSG00000065308
Protein
UniProt ID Q15035
Protein name Translocating chain-associated membrane protein 2
Protein function Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) co
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF08390 TRAM1 46 110 TRAM1-like protein Family
PF03798 TRAM_LAG1_CLN8 113 312 TLC domain Domain
Sequence
Sequence length 370
Interactions View interactions