Gene Gene information from NCBI Gene database.
Entrez ID 9697
Gene name Translocation associated membrane protein 2
Gene symbol TRAM2
Synonyms (NCBI Gene)
-
Chromosome 6
Chromosome location 6p12.2
Summary TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum (ER) membrane.[supplied by OMIM, Jul 2004]
miRNA miRNA information provided by mirtarbase database.
1912
miRTarBase ID miRNA Experiments Reference
MIRT023369 hsa-miR-122-5p Microarray 17612493
MIRT025874 hsa-miR-7-5p Sequencing 20371350
MIRT027751 hsa-miR-98-5p Microarray 19088304
MIRT029785 hsa-miR-26b-5p Microarray 19088304
MIRT520514 hsa-miR-32-5p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
8
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 14749390
GO:0005789 Component Endoplasmic reticulum membrane IBA
GO:0006616 Process SRP-dependent cotranslational protein targeting to membrane, translocation IEA
GO:0015031 Process Protein transport IEA
GO:0016020 Component Membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608485 16855 ENSG00000065308
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q15035
Protein name Translocating chain-associated membrane protein 2
Protein function Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) co
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF08390 TRAM1 46 110 TRAM1-like protein Family
PF03798 TRAM_LAG1_CLN8 113 312 TLC domain Domain
Sequence
Sequence length 370
Interactions View interactions