Gene Gene information from NCBI Gene database.
Entrez ID 9689
Gene name Basic leucine zipper and W2 domains 1
Gene symbol BZW1
Synonyms (NCBI Gene)
5MP2BZAP45Nbla10236
Chromosome 2
Chromosome location 2q33.1
miRNA miRNA information provided by mirtarbase database.
1905
miRTarBase ID miRNA Experiments Reference
MIRT031563 hsa-miR-16-5p Proteomics 18668040
MIRT050244 hsa-miR-25-3p CLASH 23622248
MIRT052785 hsa-miR-1260b CLASH 23622248
MIRT705176 hsa-miR-4293 HITS-CLIP 23313552
MIRT352034 hsa-miR-4459 HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
10
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0005515 Function Protein binding IPI 32814053
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IDA 10942595, 25468996
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
619252 18380 ENSG00000082153
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7L1Q6
Protein name eIF5-mimic protein 2 (Basic leucine zipper and W2 domain-containing protein 1) (Protein Orf)
Protein function Translation initiation regulator which represses repeat-associated non-AUG (RAN) initiated translation probably by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function (PubMed:29470543, PubMed:34260931)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02020 W2 337 414 eIF4-gamma/eIF5/eIF2-epsilon Family
Sequence
MNNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAK
LDYRRYAETLFDILVAGGMLAPGGTLADDMMRTDVCVFAAQEDLETMQAFAQVFNKLIRR
YKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGVLLANGTLNASILNSLYNENLVKEG
VSAAFAVKLFKSWINEKDINAVAASLRKVSMDNRLMELFPANKQSVEHFTKYFTEAGLKE
LSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNIPEPVVIGIVWSSV
MSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQ
KIVVLFYKAEVLSEEPILKWYKDAHVAKGKSVFLEQMKKFVEWLKNAEEESESE
AEEGD
Sequence length 419
Interactions View interactions