GREB1 (growth regulating estrogen receptor binding 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9687 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Growth regulating estrogen receptor binding 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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GREB1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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Chromosome
Chromosome number
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2 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2p25.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q4ZG55 | ||||||||||
| Protein name | Protein GREB1 (Gene regulated in breast cancer 1 protein) | ||||||||||
| Protein function | May play a role in estrogen-stimulated cell proliferation. Acts as a regulator of hormone-dependent cancer growth in breast and prostate cancers. | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in proliferating prostatic tissue and prostate cancer. {ECO:0000269|PubMed:16496412}. | ||||||||||
| Sequence |
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| Sequence length | 1949 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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