Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9686
Gene name Gene Name - the full gene name approved by the HGNC.
Vestigial like family member 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
VGLL4
Synonyms (NCBI Gene) Gene synonyms aliases
VGL-4
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p25.3-p25.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019746 hsa-miR-375 Microarray 20215506
MIRT052473 hsa-let-7a-5p CLASH 23622248
MIRT051646 hsa-let-7e-5p CLASH 23622248
MIRT438320 hsa-miR-222-3p ChIP-seq, Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot 26045994
MIRT438320 hsa-miR-222-3p ChIP-seq, Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot 26045994
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001223 Function Transcription coactivator binding IBA 21873635
GO:0005515 Function Protein binding IPI 21044950, 24525233, 28051067, 32296183
GO:0005634 Component Nucleus ISS
GO:0030178 Process Negative regulation of Wnt signaling pathway IDA 28051067
GO:0030308 Process Negative regulation of cell growth IDA 28051067
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
618692 28966 ENSG00000144560
Protein
UniProt ID Q14135
Protein name Transcription cofactor vestigial-like protein 4 (Vgl-4)
Protein function May act as a specific coactivator for the mammalian TEFs.
PDB 8YTF
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15245 VGLL4 4 224 Transcription cofactor vestigial-like protein 4 Family
Sequence
Sequence length 290
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Chronic obstructive pulmonary disease Chronic Obstructive Airway Disease 30804561 ClinVar
Anorexia Anorexia GWAS
Ischemic Stroke Ischemic Stroke GWAS
Insomnia Insomnia GWAS
Associations from Text Mining
Disease Name Relationship Type References
Atherosclerosis Associate 33456372
Breast Neoplasms Associate 30760814, 36606584
Carcinoma Hepatocellular Associate 29950605, 32323824
Carcinoma Squamous Cell Inhibit 34004031
Cardiovascular Diseases Associate 33456372
Corneal Endothelial Cell Loss Inhibit 33456372
Endometrial Neoplasms Associate 26689674
Inflammation Associate 33456372
Neoplasms Associate 30760814, 32323824, 33456372, 35766997
Neoplasms Inhibit 34004031