N4BP1 (NEDD4 binding protein 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9683 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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NEDD4 binding protein 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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N4BP1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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Chromosome
Chromosome number
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16 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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16q12.1 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | O75113 | ||||||||||
Protein name | NEDD4-binding protein 1 (N4BP1) (EC 3.1.-.-) | ||||||||||
Protein function | Potent suppressor of cytokine production that acts as a regulator of innate immune signaling and inflammation. Acts as a key negative regulator of select cytokine and chemokine responses elicited by TRIF-independent Toll-like receptors (TLRs), t | ||||||||||
PDB | 6Q3V | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Detected in heart, lung, brain, liver, skeletal muscle, pancreas, kidney, spleen, testis and ovary. {ECO:0000269|PubMed:9734811}. | ||||||||||
Sequence |
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Sequence length | 896 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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