Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	9668
Gene name	Zinc finger protein 432
Gene symbol	ZNF432
Synonyms (NCBI Gene)	-
Chromosome	19
Chromosome location	19q13.41

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miRTarBase ID	miRNA	Experiments	Reference
MIRT044843	hsa-miR-320a	CLASH	23622248
MIRT043010	hsa-miR-324-3p	CLASH	23622248
MIRT035850	hsa-miR-1260a	CLASH	23622248
MIRT706582	hsa-miR-1245a	HITS-CLIP	21572407
MIRT706580	hsa-miR-8079	HITS-CLIP	21572407
MIRT706581	hsa-miR-6513-3p	HITS-CLIP	21572407
MIRT706579	hsa-miR-6843-3p	HITS-CLIP	21572407
MIRT706578	hsa-miR-6848-3p	HITS-CLIP	21572407
MIRT451132	hsa-miR-4731-3p	PAR-CLIP	23592263
MIRT451133	hsa-miR-4801	PAR-CLIP	23592263
MIRT451131	hsa-miR-3120-3p	PAR-CLIP	23592263
MIRT451130	hsa-miR-4719	PAR-CLIP	23592263
MIRT706582	hsa-miR-1245a	HITS-CLIP	21572407
MIRT706580	hsa-miR-8079	HITS-CLIP	21572407
MIRT706581	hsa-miR-6513-3p	HITS-CLIP	21572407
MIRT706579	hsa-miR-6843-3p	HITS-CLIP	21572407
MIRT706578	hsa-miR-6848-3p	HITS-CLIP	21572407
MIRT451132	hsa-miR-4731-3p	PAR-CLIP	23592263
MIRT451133	hsa-miR-4801	PAR-CLIP	23592263
MIRT451131	hsa-miR-3120-3p	PAR-CLIP	23592263
MIRT451130	hsa-miR-4719	PAR-CLIP	23592263
MIRT2670311	hsa-miR-1243	CLIP-seq
MIRT2670312	hsa-miR-1284	CLIP-seq
MIRT2670313	hsa-miR-1290	CLIP-seq
MIRT2670314	hsa-miR-141	CLIP-seq
MIRT2670315	hsa-miR-200a	CLIP-seq
MIRT2670316	hsa-miR-203	CLIP-seq
MIRT2670317	hsa-miR-216b	CLIP-seq
MIRT2670318	hsa-miR-3167	CLIP-seq
MIRT2670319	hsa-miR-3668	CLIP-seq
MIRT2670320	hsa-miR-4318	CLIP-seq
MIRT2670321	hsa-miR-4517	CLIP-seq
MIRT2670322	hsa-miR-4643	CLIP-seq
MIRT2670323	hsa-miR-466	CLIP-seq
MIRT2670324	hsa-miR-4693-5p	CLIP-seq
MIRT2670325	hsa-miR-4789-3p	CLIP-seq
MIRT2670326	hsa-miR-4797-3p	CLIP-seq
MIRT2670327	hsa-miR-485-3p	CLIP-seq
MIRT2670328	hsa-miR-510	CLIP-seq
MIRT2670329	hsa-miR-512-5p	CLIP-seq
MIRT2670330	hsa-miR-876-5p	CLIP-seq
MIRT2670331	hsa-miR-892a	CLIP-seq
MIRT2670311	hsa-miR-1243	CLIP-seq
MIRT2670312	hsa-miR-1284	CLIP-seq
MIRT2670313	hsa-miR-1290	CLIP-seq
MIRT2670314	hsa-miR-141	CLIP-seq
MIRT2670315	hsa-miR-200a	CLIP-seq
MIRT2670316	hsa-miR-203	CLIP-seq
MIRT2670318	hsa-miR-3167	CLIP-seq
MIRT2670319	hsa-miR-3668	CLIP-seq
MIRT2670321	hsa-miR-4517	CLIP-seq
MIRT2670322	hsa-miR-4643	CLIP-seq
MIRT2670323	hsa-miR-466	CLIP-seq
MIRT2670325	hsa-miR-4789-3p	CLIP-seq
MIRT2670326	hsa-miR-4797-3p	CLIP-seq
MIRT2670327	hsa-miR-485-3p	CLIP-seq
MIRT2670328	hsa-miR-510	CLIP-seq
MIRT2670329	hsa-miR-512-5p	CLIP-seq
MIRT2670330	hsa-miR-876-5p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0003684	Function	Damaged DNA binding	IDA	37823600
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IDA	37823600
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005730	Component	Nucleolus	IDA	37823600
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006974	Process	DNA damage response	IDA	37823600
GO:0008270	Function	Zinc ion binding	IEA
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	37823600
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
620554	20810	ENSG00000256087

O94892

Protein name

Zinc finger protein 432

Protein function

Homologous recombination repressor that functions as a poly(ADP-ribose) (PAR) reader regulating DNA damage response and PARP inhibition. Once recruited to DNA lesions via DNA-, in a PAR-dependent mechanism, stimulates PARP1 activity (PubMed:3782

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	7 → 48	KRAB box	Family
PF00096	zf-C2H2	205 → 227	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	233 → 255	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	261 → 283	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	289 → 311	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	317 → 339	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	345 → 367	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	373 → 395	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	401 → 423	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	429 → 451	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	457 → 479	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	485 → 507	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	513 → 535	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	541 → 563	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	597 → 619	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	625 → 647	Zinc finger, C2H2 type	Domain

Sequence

MINAQELLTLEDVTVEFTWEEWQLLGPFQKDLYRDVMLEIYSNLLSMGYQVSKPDALSKL
ERGEEPWTMEDERHSRICPENNEVDDHLQDHLENQRMLKSVEQYHEHNAFGNTASQTKSL
CLFRENHDTFELYIKTLKSNLSLVNQNKSCEINNSTKFSGDGKSFLHGNYEELYSAAKFS
VSTKANSTKSQVSKHQRTHEIEKNHVCSECGKAFVKKSQLTDHERVHTGEKPYGCTLCAK
VFSRKSRLNEHQRIHKREKSFICSECGKVFTMKSRLIEHQRTHTGEKPYICNECGKGFPG
KRNLIVHQRNHTGEKSYICSECGKGFTGKSMLIIHQRTHTGEKPYICSECGKGFTTKHYV
IIHQRNHTGEKPYICNECGKGFTMKSRMIEHQRTHTGEKPYICSECGKGFPRKSNLIVHQ
RNHTVEKSYLCSECGKGFTVKSMLIIHQRTHTGEKPYTCSECGKGFPLKSRLIVHQRTHT
GEKPYRCSECGKGFIVNSGLMLHQRTHTGEKPYICNECGKGFAFKSNLVVHQRTHTGEKP
FMCSECGKGFTMKRYLIVHQQIHTEEKSCICSECGRGFAKETELALHKQVHTGEKPYGCN
ECGKGFTMKSRLIVHQRTHTGEKPFVCSECRKAFSSKRNLIVHQRTHNGNKP

Sequence length

652

Interactions

View interactions

	Reactome
			Generic Transcription Pathway

ZNF432 (zinc finger protein 432)