Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9668
Gene name Gene Name - the full gene name approved by the HGNC.	Zinc finger protein 432
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ZNF432
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19q13.41

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miRTarBase ID	miRNA	Experiments	Reference
MIRT044843	hsa-miR-320a	CLASH	23622248
MIRT043010	hsa-miR-324-3p	CLASH	23622248
MIRT035850	hsa-miR-1260a	CLASH	23622248
MIRT706582	hsa-miR-1245a	HITS-CLIP	21572407
MIRT706580	hsa-miR-8079	HITS-CLIP	21572407
MIRT706581	hsa-miR-6513-3p	HITS-CLIP	21572407
MIRT706579	hsa-miR-6843-3p	HITS-CLIP	21572407
MIRT706578	hsa-miR-6848-3p	HITS-CLIP	21572407
MIRT451132	hsa-miR-4731-3p	PAR-CLIP	23592263
MIRT451133	hsa-miR-4801	PAR-CLIP	23592263
MIRT451131	hsa-miR-3120-3p	PAR-CLIP	23592263
MIRT451130	hsa-miR-4719	PAR-CLIP	23592263
MIRT706582	hsa-miR-1245a	HITS-CLIP	21572407
MIRT706580	hsa-miR-8079	HITS-CLIP	21572407
MIRT706581	hsa-miR-6513-3p	HITS-CLIP	21572407
MIRT706579	hsa-miR-6843-3p	HITS-CLIP	21572407
MIRT706578	hsa-miR-6848-3p	HITS-CLIP	21572407
MIRT451132	hsa-miR-4731-3p	PAR-CLIP	23592263
MIRT451133	hsa-miR-4801	PAR-CLIP	23592263
MIRT451131	hsa-miR-3120-3p	PAR-CLIP	23592263
MIRT451130	hsa-miR-4719	PAR-CLIP	23592263
MIRT2670311	hsa-miR-1243	CLIP-seq
MIRT2670312	hsa-miR-1284	CLIP-seq
MIRT2670313	hsa-miR-1290	CLIP-seq
MIRT2670314	hsa-miR-141	CLIP-seq
MIRT2670315	hsa-miR-200a	CLIP-seq
MIRT2670316	hsa-miR-203	CLIP-seq
MIRT2670317	hsa-miR-216b	CLIP-seq
MIRT2670318	hsa-miR-3167	CLIP-seq
MIRT2670319	hsa-miR-3668	CLIP-seq
MIRT2670320	hsa-miR-4318	CLIP-seq
MIRT2670321	hsa-miR-4517	CLIP-seq
MIRT2670322	hsa-miR-4643	CLIP-seq
MIRT2670323	hsa-miR-466	CLIP-seq
MIRT2670324	hsa-miR-4693-5p	CLIP-seq
MIRT2670325	hsa-miR-4789-3p	CLIP-seq
MIRT2670326	hsa-miR-4797-3p	CLIP-seq
MIRT2670327	hsa-miR-485-3p	CLIP-seq
MIRT2670328	hsa-miR-510	CLIP-seq
MIRT2670329	hsa-miR-512-5p	CLIP-seq
MIRT2670330	hsa-miR-876-5p	CLIP-seq
MIRT2670331	hsa-miR-892a	CLIP-seq
MIRT2670311	hsa-miR-1243	CLIP-seq
MIRT2670312	hsa-miR-1284	CLIP-seq
MIRT2670313	hsa-miR-1290	CLIP-seq
MIRT2670314	hsa-miR-141	CLIP-seq
MIRT2670315	hsa-miR-200a	CLIP-seq
MIRT2670316	hsa-miR-203	CLIP-seq
MIRT2670318	hsa-miR-3167	CLIP-seq
MIRT2670319	hsa-miR-3668	CLIP-seq
MIRT2670321	hsa-miR-4517	CLIP-seq
MIRT2670322	hsa-miR-4643	CLIP-seq
MIRT2670323	hsa-miR-466	CLIP-seq
MIRT2670325	hsa-miR-4789-3p	CLIP-seq
MIRT2670326	hsa-miR-4797-3p	CLIP-seq
MIRT2670327	hsa-miR-485-3p	CLIP-seq
MIRT2670328	hsa-miR-510	CLIP-seq
MIRT2670329	hsa-miR-512-5p	CLIP-seq
MIRT2670330	hsa-miR-876-5p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0003684	Function	Damaged DNA binding	IDA	37823600
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IDA	37823600
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005730	Component	Nucleolus	IDA	37823600
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006974	Process	DNA damage response	IDA	37823600
GO:0008270	Function	Zinc ion binding	IEA
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	37823600
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
620554	20810	ENSG00000256087

Protein

UniProt ID

O94892

Protein name

Zinc finger protein 432

Protein function

Homologous recombination repressor that functions as a poly(ADP-ribose) (PAR) reader regulating DNA damage response and PARP inhibition. Once recruited to DNA lesions via DNA-, in a PAR-dependent mechanism, stimulates PARP1 activity (PubMed:3782

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	7 → 48	KRAB box	Family
PF00096	zf-C2H2	205 → 227	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	233 → 255	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	261 → 283	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	289 → 311	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	317 → 339	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	345 → 367	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	373 → 395	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	401 → 423	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	429 → 451	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	457 → 479	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	485 → 507	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	513 → 535	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	541 → 563	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	597 → 619	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	625 → 647	Zinc finger, C2H2 type	Domain

Sequence

MINAQELLTLEDVTVEFTWEEWQLLGPFQKDLYRDVMLEIYSNLLSMGYQVSKPDALSKL
ERGEEPWTMEDERHSRICPENNEVDDHLQDHLENQRMLKSVEQYHEHNAFGNTASQTKSL
CLFRENHDTFELYIKTLKSNLSLVNQNKSCEINNSTKFSGDGKSFLHGNYEELYSAAKFS
VSTKANSTKSQVSKHQRTHEIEKNHVCSECGKAFVKKSQLTDHERVHTGEKPYGCTLCAK
VFSRKSRLNEHQRIHKREKSFICSECGKVFTMKSRLIEHQRTHTGEKPYICNECGKGFPG
KRNLIVHQRNHTGEKSYICSECGKGFTGKSMLIIHQRTHTGEKPYICSECGKGFTTKHYV
IIHQRNHTGEKPYICNECGKGFTMKSRMIEHQRTHTGEKPYICSECGKGFPRKSNLIVHQ
RNHTVEKSYLCSECGKGFTVKSMLIIHQRTHTGEKPYTCSECGKGFPLKSRLIVHQRTHT
GEKPYRCSECGKGFIVNSGLMLHQRTHTGEKPYICNECGKGFAFKSNLVVHQRTHTGEKP
FMCSECGKGFTMKRYLIVHQQIHTEEKSCICSECGRGFAKETELALHKQVHTGEKPYGCN
ECGKGFTMKSRLIVHQRTHTGEKPFVCSECRKAFSSKRNLIVHQRTHNGNKP

Sequence length

652

Interactions

View interactions

	Reactome
			Generic Transcription Pathway

ZNF432 (zinc finger protein 432)