ZNF516 (zinc finger protein 516)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 9658 |
| Gene name | Zinc finger protein 516 |
| Gene symbol | ZNF516 |
| Synonyms (NCBI Gene) |
HsT287
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| Chromosome | 18 |
| Chromosome location | 18q23 |
| Summary | Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a zinc-finger protein, and belongs to the krueppel C2H2-type zinc-finger protei |
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miRNA
miRNA information provided by mirtarbase database.
424
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q92618 | ||||||||||||||||||||||||||||||
| Protein name | Zinc finger protein 516 | ||||||||||||||||||||||||||||||
| Protein function | Transcriptional regulator that binds to the promoter and activates the transcription of genes promoting brown adipose tissue (BAT) differentiation. Among brown adipose tissue-specific genes, binds the proximal region of the promoter of the UCP1 | ||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1163 | ||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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