RALGPS1 (Ral GEF with PH domain and SH3 binding motif 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 9649 |
| Gene name | Ral GEF with PH domain and SH3 binding motif 1 |
| Gene symbol | RALGPS1 |
| Synonyms (NCBI Gene) |
RALGEF2RALGPS1A
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| Chromosome | 9 |
| Chromosome location | 9q33.3 |
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miRNA
miRNA information provided by mirtarbase database.
449
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
13
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q5JS13 | |||||||||||||||
| Protein name | Ras-specific guanine nucleotide-releasing factor RalGPS1 (Ral GEF with PH domain and SH3-binding motif 1) (Ral guanine nucleotide exchange factor 2) (RalGEF 2) (RalA exchange factor RalGPS1) | |||||||||||||||
| Protein function | Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for. | |||||||||||||||
| PDB | 3QXL | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lowe | |||||||||||||||
| Sequence |
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| Sequence length | 557 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
2
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