PPM1F (protein phosphatase, Mg2+/Mn2+ dependent 1F)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 9647 |
| Gene name | Protein phosphatase, Mg2+/Mn2+ dependent 1F |
| Gene symbol | PPM1F |
| Synonyms (NCBI Gene) |
CAMKPCaMKPaseFEM-2POPX2hFEM-2
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| Chromosome | 22 |
| Chromosome location | 22q11.22 |
| Summary | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange f |
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miRNA
miRNA information provided by mirtarbase database.
519
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
37
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P49593 | ||||||||||
| Protein name | Protein phosphatase 1F (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (Protein fem-2 homolog) (hFem-2) | ||||||||||
| Protein function | Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis. | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 454 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
2
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