Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9637
Gene name Gene Name - the full gene name approved by the HGNC.
Fasciculation and elongation protein zeta 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
FEZ2
Synonyms (NCBI Gene) Gene synonyms aliases
HUM3CL
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2p22.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin. [provided by RefSeq, Jul
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT528032 hsa-miR-4282 PAR-CLIP 22012620
MIRT528031 hsa-miR-634 PAR-CLIP 22012620
MIRT528030 hsa-miR-302a-5p PAR-CLIP 22012620
MIRT528029 hsa-miR-3682-5p PAR-CLIP 22012620
MIRT528027 hsa-miR-4477a PAR-CLIP 22012620
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 14690447, 24705354, 32296183, 32814053
GO:0005737 Component Cytoplasm IBA 21873635
GO:0007165 Process Signal transduction TAS 9096408
GO:0007399 Process Nervous system development TAS 9096408
GO:0007411 Process Axon guidance TAS 9096408
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
604826 3660 ENSG00000171055
Protein
UniProt ID Q9UHY8
Protein name Fasciculation and elongation protein zeta-2 (Zygin II) (Zygin-2)
Protein function Involved in axonal outgrowth and fasciculation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07763 FEZ 51 286 FEZ-like protein Family
Tissue specificity TISSUE SPECIFICITY: Expressed in nonneural tissues, such as heart, lung, spleen, muscle, testis, placenta and melanocytes.
Sequence
Sequence length 353
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Metabolic Syndrome Metabolic Syndrome GWAS
Associations from Text Mining
Disease Name Relationship Type References
Bipolar Disorder Associate 33168801
Ovarian Neoplasms Associate 35038288